GWAS1200473_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1200473_H (corneal topography QTL GWAS1200473 (human)) Homo sapiens

Symbol: GWAS1200473_H
Name: corneal topography QTL GWAS1200473 (human)
RGD ID: 597104399
Trait: corneal topography
LOD Score: Not Available
P Value: 2.0E-22
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,126,840 - 11,126,841RGD_MAPPER_PIPELINEGRCh38
GRCh37111,186,897 - 11,186,898RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1200473_HHumancorneal topography  IAGPrs3737611405850206 GWAS_CATALOGPMID:32193507

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
68533MTORmechanistic target of rapamycin kinase11110653511262551Human


Peak: (rs3737611)
Human AssemblyChrPosition (strand)Source
GRCh38111,126,840 - 11,126,841RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597104646GWAS1200720_Hcorneal topography QTL GWAS1200720 (human)7e-21corneal topography11112684011126841Human
597104399GWAS1200473_Hcorneal topography QTL GWAS1200473 (human)2e-22corneal topography11112684011126841Human
597103645GWAS1199719_Hcorneal topography QTL GWAS1199719 (human)1e-46corneal topography11112684011126841Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1200473_H GCST90012799 Corneal curvature 35,422 individuals (>=25 years old) A NR 2E-22 21.699 rs3737611 0.0425 corneal topography (EFO:0004345)
 PMID:32193507
GWAS1199719_H GCST90012795 Corneal curvature 29,580 European ancestry individuals, 14,462 Asian ancestry individuals A 0.98 1E-46 46 rs3737611 0.041 corneal topography (EFO:0004345)
 PMID:32193507
GWAS1200720_H GCST90012797 Corneal curvature 14,462 Asian ancestry individuals A 0.83 7E-21 20.155 rs3737611 0.041 corneal topography (EFO:0004345)
 PMID:32193507
Database
Acc Id
Source(s)
GWAS Catalog GCST90012799 GWAS Catalog

Note Type Note Reference