GWAS1198125_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1198125_H (low density lipoprotein cholesterol measurement QTL GWAS1198125 (human)) Homo sapiens

Symbol: GWAS1198125_H
Name: low density lipoprotein cholesterol measurement QTL GWAS1198125 (human)
RGD ID: 597102051
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 5.0E-43
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381424,402,720 - 24,402,721RGD_MAPPER_PIPELINEGRCh38
GRCh371424,871,926 - 24,871,927RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1198125_HHumanblood low density lipoprotein cholesterol level  IAGPrs11621792405850206 GWAS_CATALOGPMID:32493714

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1198125_HHumanlow density lipoprotein cholesterol measurement  IAGPrs11621792405850206 GWAS_CATALOGPMID:32493714

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1345252NYNRINNYN domain and retroviral integrase containing142439900324419283Human


Peak: (rs11621792)
Human AssemblyChrPosition (strand)Source
GRCh381424,402,720 - 24,402,721RGD_MAPPER_PIPELINE


1 to 10 of 63 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597099668GWAS1195742_Hsex hormone-binding globulin measurement QTL GWAS1195742 (human)1e-25sex hormone-binding globulin measurement142440272024402721Human
597191323GWAS1287397_Hsex hormone-binding globulin measurement QTL GWAS1287397 (human)3e-68sex hormone-binding globulin measurement142440272024402721Human
597272988GWAS1369062_Htotal cholesterol measurement QTL GWAS1369062 (human)1e-37total cholesterol measurementblood total cholesterol level (CMO:0000051)142440272024402721Human
597023251GWAS1119325_Hlow density lipoprotein cholesterol measurement QTL GWAS1119325 (human)1e-13serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)142440272024402721Human
597023250GWAS1119324_Hlow density lipoprotein cholesterol measurement QTL GWAS1119324 (human)6e-12blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)142440272024402721Human
597606169GWAS1663029_Hserum alanine aminotransferase measurement QTL GWAS1663029 (human)2e-21serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)142440272024402721Human
597150480GWAS1246554_Htotal cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS1246554 (human)4e-12low density lipoprotein cholesterol measurement, lipid measurementblood high density lipoprotein cholesterol level (CMO:0000052)142440272024402721Human
597605908GWAS1662768_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS1662768 (human)4e-14aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)142440272024402721Human
597319445GWAS1415519_Hlow density lipoprotein cholesterol measurement QTL GWAS1415519 (human)6e-55low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142440272024402721Human
597165975GWAS1262049_Hcholesteryl ester measurement, low density lipoprotein cholesterol measurement QTL GWAS1262049 (human)8e-11blood lipid amount (VT:0003949)blood low density lipoprotein cholesterol level (CMO:0000053)142440272024402721Human

1 to 10 of 63 rows


1 to 20 of 92 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1198125_H GCST90002412 Low density lipoprotein cholesterol levels 431,167 European ancestry individuals C 0.547101 5E-43 42.302 rs11621792 0.0267004 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32493714
GWAS1119324_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C 0.551 6E-12 11.222 rs11621792 0.033 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
GWAS1119325_H GCST007141 Low density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C NR 1E-13 13 rs11621792 0.033 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29507422
GWAS1131985_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals C 0.547127 1E-19 19 rs11621792 0.0191305 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS1136895_H GCST010204 Low density lipoprotein cholesterol levels 324,708 British ancestry individuals ? NR 9E-23 22.046 rs11621792 0.0255 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32154731
GWAS1159066_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C 0.551 2E-10 9.699 rs11621792 0.03 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1159067_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C NR 3E-12 11.523 rs11621792 0.031 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1655960_H GCST90479506 Alanine transaminase (ALT, maximum, inv-norm transformed) 115,123 African American or Afro-Caribbean individuals, 56,102 Hispanic or Latin American individuals, 6,054 East Asian ancestry individuals, 406,783 European ancestry individuals C 0.6358 3E-15 14.523 rs11621792 0.02042 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:39024449
GWAS1656078_H GCST90479507 Alanine transaminase (ALT, mean, inv-norm transformed) 115,128 African American or Afro-Caribbean individuals, 56,001 Hispanic or Latin American individuals, 6,050 East Asian ancestry individuals, 406,803 European ancestry individuals C 0.6358 6E-15 14.222 rs11621792 0.02065 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:39024449
GWAS1662768_H GCST90475121 Aspartate aminotransferase (AST, mean, inv-norm transformed) 389,192 European ancestry individuals C 0.5518 4E-14 13.398 rs11621792 0.02034 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:39024449
None Available GCST90475115 Alanine transaminase (ALT, minimum, inv-norm transformed) 406,784 European ancestry individuals C 0.5518 3E-15 14.523 rs11621792 0.01942 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:39024449
GWAS1663029_H GCST90475112 Alanine transaminase (ALT, mean, inv-norm transformed) 406,803 European ancestry individuals C 0.5517 2E-21 20.699 rs11621792 0.02333 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:39024449
GWAS1663221_H GCST90475109 Alanine transaminase (ALT, maximum, inv-norm transformed) 406,783 European ancestry individuals C 0.5517 4E-20 19.398 rs11621792 0.02251 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:39024449
GWAS1191026_H GCST002898 LDL cholesterol up 62,166 European ancestry individuals T 0.42 2E-8 7.699 rs11621792 0.037 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:25961943
GWAS1192409_H GCST90012108 Sex hormone-binding globulin levels adjusted for BMI 180,094 European ancestry men C 0.546324 2E-28 27.699 rs11621792 0.0127693 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS1192960_H GCST90012110 Sex hormone-binding globulin levels adjusted for BMI 368,929 European ancestry individuals C 0.547031 2E-117 116.699 rs11621792 0.0188283 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS1193261_H GCST90012113 Total testosterone levels 194,453 European ancestry men C 0.546261 7E-9 8.155 rs11621792 0.0176248 testosterone measurement (EFO:0004908)
 PMID:32042192
GWAS1194179_H GCST90012111 Sex hormone-binding globulin levels 370,125 European ancestry individuals C 0.547031 7E-90 89.155 rs11621792 0.0182549 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS1195742_H GCST90012109 Sex hormone-binding globulin levels 180,726 European ancestry men C 0.546324 1E-25 25 rs11621792 0.012749 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS1198140_H GCST90011900 Serum alkaline phosphatase levels 390,964 European ancestry individuals C 0.55 2E-29 28.699 rs11621792 11.2 alkaline phosphatase measurement (EFO:0004533)
 PMID:33547301
1 to 20 of 92 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90002412 GWAS Catalog

Note Type Note Reference