GWAS1151191_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1151191_H (systolic blood pressure QTL GWAS1151191 (human)) Homo sapiens

Symbol: GWAS1151191_H
Name: systolic blood pressure QTL GWAS1151191 (human)
RGD ID: 597055117
Trait: systolic blood pressure
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38612,295,754 - 12,295,755RGD_MAPPER_PIPELINEGRCh38
GRCh37612,295,987 - 12,295,988RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1151191_HHumansystolic blood pressure  IAGPrs1630736405850206 GWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1151191_HHumansystolic blood pressure  IAGPrs1630736405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
730848EDN1endothelin 161223051612297194Human


Peak: (rs1630736)
Human AssemblyChrPosition (strand)Source
GRCh38612,295,754 - 12,295,755RGD_MAPPER_PIPELINE


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
597039572GWAS1135646_Hpulse pressure measurement QTL GWAS1135646 (human)4e-10pulse pressure measurementpulse pressure (CMO:0000292)61229575412295755Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597133201GWAS1229275_Hsystolic blood pressure QTL GWAS1229275 (human)1e-11systolic blood pressuresystolic blood pressure (CMO:0000004)61229575412295755Human
597259326GWAS1355400_Haortic measurement QTL GWAS1355400 (human)2e-12aortic measurementaorta measurement (CMO:0001474)61229575412295755Human
597244862GWAS1340936_Haortic measurement QTL GWAS1340936 (human)5e-13aortic measurementaorta measurement (CMO:0001474)61229575412295755Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human

1 to 10 of 20 rows


1 to 15 of 15 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1151191_H GCST007087 Systolic blood pressure approximately 422,000 European ancestry individuals ? NR 4E-8 7.398 rs1630736 N/A systolic blood pressure (EFO:0006335)
 PMID:30595370
GWAS1135646_H GCST007269 Pulse pressure 365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals T 0.4609 4E-10 9.398 rs1630736 0.1271 pulse pressure measurement (EFO:0005763)
 PMID:30578418
GWAS1211981_H GCST006629 Pulse pressure 757,601 European ancestry individuals T 0.464 7E-14 13.155 rs1630736 0.1319 pulse pressure measurement (EFO:0005763)
 PMID:30224653
GWAS1229275_H GCST90310294 Systolic blood pressure 1,028,980 European ancestry individuals T NR 1E-11 11 rs1630736 0.1664 systolic blood pressure (EFO:0006335)
 PMID:38689001
GWAS1752904_H GCST90094402 Ascending thoracic aortic diameter 33,637 European ancestry individuals C 0.533396 6E-14 13.222 rs1630736 0.0473982 ascending aorta diameter (OBA:2050001)
 PMID:34837083
GWAS1312060_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals T NR 2E-13 12.699 rs1630736 0.1294 pulse pressure measurement (EFO:0005763)
 PMID:38689001
GWAS1753585_H GCST90094400 Ascending thoracic aortic diameter 33,637 European ancestry individuals, 5,057 individuals C 0.54 8E-15 14.097 rs1630736 N/A ascending aorta diameter (OBA:2050001)
 PMID:34837083
GWAS1340936_H GCST90091050 Ascending aorta diameter 32,215 European ancestry individuals T 0.465 5E-13 12.302 rs1630736 0.05 aortic measurement (EFO:0020865)
 PMID:35637384
GWAS1355400_H GCST90093369 Ascending aorta maximum area 31,908 individuals C 0.536984 2E-12 11.699 rs1630736 0.0526776 aortic measurement (EFO:0020865)
 PMID:34968759
None Available GCST90093370 Ascending aorta minimum area 35,110 individuals C 0.538229 5E-13 12.302 rs1630736 0.049326 aortic measurement (EFO:0020865)
 PMID:34968759
None Available GCST90137450 Ascending aorta maximum area (MTAG) 32,590 European ancestry individuals C 0.54 2E-13 12.699 rs1630736 8.82 aortic measurement (EFO:0020865)
 PMID:35922433
GWAS1365112_H GCST90137452 Ascending aorta minimum area 15,817 European ancestry men ? NR 6E-9 8.222 rs1630736 10.59 aortic measurement (EFO:0020865)
 PMID:35922433
GWAS1365344_H GCST90137454 Ascending aorta minimum area 16,773 European ancestry women ? NR 2E-7 6.699 rs1630736 7.88 aortic measurement (EFO:0020865)
 PMID:35922433
None Available GCST90137440 Ascending aorta maximum area 32,590 European ancestry individuals C 0.54 2E-13 12.699 rs1630736 8.84 aortic measurement (EFO:0020865)
 PMID:35922433
GWAS1764536_H GCST90267390 Ascending aorta diameter 38,372 European or unknown ancestry individuals C 0.537676 8E-14 13.097 rs1630736 0.0455725 ascending aorta diameter (OBA:2050001)
 PMID:37019578
1 to 15 of 15 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST007087 GWAS Catalog

Note Type Note Reference