GWAS1115244_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1115244_H (smoking status measurement, diastolic blood pressure QTL GWAS1115244 (human)) Homo sapiens

Symbol: GWAS1115244_H
Name: smoking status measurement, diastolic blood pressure QTL GWAS1115244 (human)
RGD ID: 597019170
Trait: smoking status measurement, diastolic blood pressure
Measurement Type: diastolic blood pressure   (CMO:0000005)    
LOD Score: Not Available
P Value: 6.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,818,104 - 11,818,105RGD_MAPPER_PIPELINEGRCh38
GRCh37111,878,161 - 11,878,162RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1115244_HHumandiastolic blood pressure  IAGPrs202071545405850206 GWAS_CATALOGPMID:29455858

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1115244_HHumandiastolic blood pressure  IAGPrs202071545405850206 GWAS_CATALOGPMID:29455858
GWAS1115244_HHumansmoking status measurement  IAGPrs202071545405850206 GWAS_CATALOGPMID:29455858

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1313372CLCN6chloride voltage-gated channel 611180619111843130Human


Peak: (rs202071545)
Human AssemblyChrPosition (strand)Source
GRCh38111,818,104 - 11,818,105RGD_MAPPER_PIPELINE


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
596951383GWAS1070902_Hsmoking status measurement, systolic blood pressure QTL GWAS1070902 (human)9e-20smoking status measurement, systolic blood pressure11181810411818105Human
597019840GWAS1115914_Hsmoking status measurement, diastolic blood pressure QTL GWAS1115914 (human)2e-17smoking status measurement, diastolic blood pressurediastolic blood pressure (CMO:0000005)11181810411818105Human
597019170GWAS1115244_Hsmoking status measurement, diastolic blood pressure QTL GWAS1115244 (human)6e-16smoking status measurement, diastolic blood pressurediastolic blood pressure (CMO:0000005)11181810411818105Human
597019596GWAS1115670_Hsmoking status measurement, diastolic blood pressure QTL GWAS1115670 (human)5e-16smoking status measurement, diastolic blood pressurediastolic blood pressure (CMO:0000005)11181810411818105Human
597019599GWAS1115673_Hsmoking status measurement, systolic blood pressure QTL GWAS1115673 (human)6e-18smoking status measurement, systolic blood pressuresystolic blood pressure (CMO:0000004)11181810411818105Human
597019198GWAS1115272_Hsmoking status measurement, systolic blood pressure QTL GWAS1115272 (human)9e-20smoking status measurement, systolic blood pressuresystolic blood pressure (CMO:0000004)11181810411818105Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human

1 to 10 of 11 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1115244_H GCST006193 Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 6E-16 15.222 rs202071545 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
GWAS1115272_H GCST006195 Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 9E-20 19.046 rs202071545 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
None Available GCST006195 Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 9E-20 19.046 rs202071545 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
GWAS1115670_H GCST006193 Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers ? NR 5E-16 15.302 rs202071545 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
GWAS1115673_H GCST006192 Systolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 6E-18 17.222 rs202071545 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
None Available GCST006190 Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 6E-16 15.222 rs202071545 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
None Available GCST006192 Systolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 9E-20 19.046 rs202071545 N/A smoking status measurement (EFO:0006527)
systolic blood pressure (EFO:0006335)
 PMID:29455858
GWAS1115914_H GCST006190 Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers ? NR 2E-17 16.699 rs202071545 N/A smoking status measurement (EFO:0006527)
diastolic blood pressure (EFO:0006336)
 PMID:29455858
Database
Acc Id
Source(s)
GWAS Catalog GCST006190 GWAS Catalog
  GCST006193 GWAS Catalog

Note Type Note Reference