GWAS1062955_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1062955_H (diastolic blood pressure QTL GWAS1062955 (human)) Homo sapiens

Symbol: GWAS1062955_H
Name: diastolic blood pressure QTL GWAS1062955 (human)
RGD ID: 407413979
Trait: diastolic blood pressure
Measurement Type: diastolic blood pressure   (CMO:0000005)    
LOD Score: Not Available
P Value: 5.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381540,025,591 - 40,025,592RGD_MAPPER_PIPELINEGRCh38
GRCh371540,317,792 - 40,317,793RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1062955_HHumandiastolic blood pressure  IAGPrs11070245405850206Based on the EFO term IDGWAS_CATALOGPMID:38689001

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS1062955_HHumandiastolic blood pressure  IAGPrs11070245405850206 GWAS_CATALOGPMID:38689001
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1322904EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 4153993411540035591Human

Position Markers

Peak: (rs11070245)
Human AssemblyChrPosition (strand)Source
GRCh381540,025,591 - 40,025,592RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407413979GWAS1062955_Hdiastolic blood pressure QTL GWAS1062955 (human)5e-17diastolic blood pressurediastolic blood pressure (CMO:0000005)154002559140025592Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407365090GWAS1014066_Hsystolic blood pressure QTL GWAS1014066 (human)2e-16systolic blood pressuresystolic blood pressure (CMO:0000004)154002559140025592Human
407415294GWAS1064270_Hpulse pressure measurement QTL GWAS1064270 (human)0.0000003pulse pressure measurementpulse pressure (CMO:0000292)154002559140025592Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS1014066_H GCST90310294 Systolic blood pressure 1,028,980 European ancestry individuals G NR 2E-16 15.699 rs11070245 0.1989 systolic blood pressure (EFO:0006335)
 PMID:38689001
GWAS1062955_H GCST90310295 Diastolic blood pressure 1,028,980 European ancestry individuals G NR 5E-17 16.302 rs11070245 0.1264 diastolic blood pressure (EFO:0006336)
 PMID:38689001
GWAS1064270_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals G NR 3E-7 6.523 rs11070245 0.0889 pulse pressure measurement (EFO:0005763)
 PMID:38689001
Database Acc Id Source(s)
GWAS Catalog GCST90310295 GWAS Catalog

RGD Curation Notes
Note Type Note Reference