QTL |
GWAS Catalog Study |
Disease Trait |
Study Size |
Risk Allele |
Risk Allele Frequency |
P Value |
P Value MLOG |
Peak Marker |
Reported Odds Ratio or Beta-coefficient |
Ontology Accession |
PubMed |
GWAS547365_H |
GCST007140 |
High density lipoprotein cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.7 |
1E-110 |
110 |
rs15285 |
0.091 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:29507422 |
GWAS547366_H |
GCST007140 |
High density lipoprotein cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.705 |
1E-16 |
16 |
rs15285 |
0.111 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:29507422 |
GWAS547367_H |
GCST007140 |
High density lipoprotein cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.803 |
1E-10 |
10 |
rs15285 |
0.109 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:29507422 |
GWAS547368_H |
GCST007140 |
High density lipoprotein cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
NR |
3E-139 |
138.523 |
rs15285 |
0.094 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:29507422 |
GWAS573444_H |
GCST009240 |
Serum metabolite levels (CMS) |
6,263 Finnish ancestry men |
? |
NR |
1E-14 |
14 |
rs15285 |
0.08341065 |
serum metabolite measurement (EFO:0005653)
|
PMID:31636271 |
GWAS577744_H |
GCST010173 |
Triglyceride levels |
324,694 British ancestry individuals |
? |
NR |
2E-459 |
458.699 |
rs15285 |
0.1223 |
triglyceride measurement (EFO:0004530)
|
PMID:32154731 |
GWAS580234_H |
GCST009368 |
HDL cholesterol levels x long total sleep time interaction (2df test) |
2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls |
? |
NR |
7E-126 |
125.155 |
rs15285 |
0.02406 |
sleep duration (EFO:0005271) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:31719535 |
GWAS607214_H |
GCST004207 |
HDL cholesterol |
19,223 British ancestry individuals from 6863 families. |
T |
0.2675 |
1E-18 |
18 |
rs15285 |
0.109238155 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:28270201 |
GWAS633496_H |
GCST008035 |
High density lipoprotein cholesterol levels |
10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals |
? |
NR |
5E-40 |
39.302 |
rs15285 |
1.587487 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:31217584 |
GWAS641486_H |
GCST008046 |
Triglyceride levels |
9,980 African American individuals, 17,856 Hispanic/Latino individuals, 2,381 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 360 individuals |
? |
NR |
6E-40 |
39.222 |
rs15285 |
0.05650247 |
triglyceride measurement (EFO:0004530)
|
PMID:31217584 |
GWAS649217_H |
GCST90132304 |
Coronary artery disease |
27,021 African American or Afro-Caribbean cases, 102,305 African American or Afro-Caribbean controls |
? |
NR |
5E-9 |
8.302 |
rs15285 |
0.0593 |
coronary artery disease (EFO:0001645)
|
PMID:35915156 |
GWAS658662_H |
GCST009450 |
Parental longevity (father's age at death or father's attained age) |
up to 699,000 European ancestry individuals |
G |
NR |
8E-10 |
9.097 |
rs15285 |
N/A |
parental longevity (EFO:0007796)
|
PMID:31484785 |
GWAS663408_H |
GCST007931 |
Medication use (HMG CoA reductase inhibitors) |
73,475 European ancestry cases, 216,910 European ancestry controls |
T |
0.28486 |
3E-21 |
20.523 |
rs15285 |
0.058676165 |
HMG CoA reductase inhibitor use measurement (EFO:0009932)
|
PMID:31015401 |
GWAS672344_H |
GCST90269667 |
Free cholesterol in medium HDL (UKB data field 23570) |
88,329 European ancestry individuals |
T |
0.287182 |
2E-81 |
80.699 |
rs15285 |
0.0914045 |
free cholesterol in medium HDL measurement (EFO:0022267)
|
PMID:36764567 |
GWAS672570_H |
GCST90269666 |
Cholesteryl esters in medium HDL (UKB data field 23569) |
88,329 European ancestry individuals |
T |
0.287182 |
7E-111 |
110.155 |
rs15285 |
0.108596 |
cholesteryl ester measurement (EFO:0010351)
|
PMID:36764567 |
GWAS673022_H |
GCST90269665 |
Cholesterol in medium HDL (UKB data field 23568) |
88,329 European ancestry individuals |
T |
0.287182 |
8E-106 |
105.097 |
rs15285 |
0.105676 |
cholesterol in medium HDL measurement (EFO:0021903)
|
PMID:36764567 |
None Available |
GCST001004 |
Triglycerides-Blood Pressure (TG-BP) |
22,161 European ancestry individuals |
A |
NR |
1E-10 |
10 |
rs15285 |
0.27 |
triglyceride measurement (EFO:0004530) blood pressure (EFO:0004325)
|
PMID:21386085 |
GWAS680175_H |
GCST90269527 |
Concentration of HDL particles (UKB data field 23430) |
88,329 European ancestry individuals |
T |
0.287182 |
6E-67 |
66.222 |
rs15285 |
0.0850471 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:36764567 |
GWAS681734_H |
GCST90269523 |
Total lipids in HDL (UKB data field 23426) |
88,329 European ancestry individuals |
T |
0.287182 |
2E-80 |
79.699 |
rs15285 |
0.0899288 |
total lipids in HDL measurement (EFO:0022307)
|
PMID:36764567 |
GWAS683638_H |
GCST90277415 |
Triacylglycerol (58:7) levels |
5,403 Finnish ancestry individuals |
T |
0.261072 |
2E-8 |
7.699 |
rs15285 |
0.123238 |
triacylglycerol 58:7 measurement (EFO:0010441)
|
PMID:37907536 |
None Available |
GCST90277402 |
Triacylglycerol (53:3) levels |
7,113 Finnish ancestry individuals |
T |
0.261072 |
5E-9 |
8.302 |
rs15285 |
0.111495 |
|
PMID:37907536 |
GWAS686556_H |
GCST90269511 |
Phospholipids in HDL (UKB data field 23414) |
88,329 European ancestry individuals |
T |
0.287182 |
1E-71 |
71 |
rs15285 |
0.0850499 |
phospholipids in HDL measurement (EFO:0022293)
|
PMID:36764567 |
GWAS690276_H |
GCST90277394 |
Triacylglycerol (51:3) levels |
7,119 Finnish ancestry individuals |
T |
0.261072 |
3E-8 |
7.523 |
rs15285 |
0.105751 |
|
PMID:37907536 |
None Available |
GCST90277396 |
Triacylglycerol (52:2) levels |
7,168 Finnish ancestry individuals |
T |
0.261072 |
2E-8 |
7.699 |
rs15285 |
0.106116 |
triacylglycerol 52:2 measurement (EFO:0010414)
|
PMID:37907536 |
GWAS690840_H |
GCST90269633 |
Triglycerides in large LDL (UKB data field 23536) |
88,329 European ancestry individuals |
T |
0.287182 |
2E-49 |
48.699 |
rs15285 |
0.076103 |
triglycerides in large LDL measurement (EFO:0022319)
|
PMID:36764567 |
GWAS699409_H |
GCST90302113 |
Phospholipids to total lipids ratio in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
1E-96 |
96 |
rs15285 |
0.0921 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
GWAS706338_H |
GCST009242 |
Serum metabolite levels |
6,263 Finnish ancestry men |
? |
NR |
9E-12 |
11.046 |
rs15285 |
0.08500996 |
serum metabolite measurement (EFO:0005653)
|
PMID:31636271 |
GWAS711706_H |
GCST90301971 |
Total cholesterol levels in HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
3E-150 |
149.523 |
rs15285 |
0.1149 |
total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS711841_H |
GCST90301969 |
Total cholesterol in HDL2 |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
9E-161 |
160.046 |
rs15285 |
0.1188 |
total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS713628_H |
GCST90301972 |
Mean diameter of HDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
3E-129 |
128.523 |
rs15285 |
0.1065 |
high density lipoprotein particle size measurement (EFO:0008592)
|
PMID:38448586 |
GWAS716334_H |
GCST005194 |
Coronary artery disease |
34,541 cases, 261,984 controls |
T |
0.29 |
8E-14 |
13.097 |
rs15285 |
0.052 |
coronary artery disease (EFO:0001645)
|
PMID:29212778 |
GWAS721065_H |
GCST90301945 |
Apolipoprotein A-I levels |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2787 |
1E-72 |
72 |
rs15285 |
0.0791 |
apolipoprotein A 1 measurement (EFO:0004614)
|
PMID:38448586 |
GWAS721895_H |
GCST90301947 |
Ratio of apolipoprotein B to apolipoprotein A1 levels |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2776 |
3E-132 |
131.523 |
rs15285 |
0.1117 |
apolipoprotein A 1 measurement (EFO:0004614) apolipoprotein B measurement (EFO:0004615)
|
PMID:38448586 |
GWAS722685_H |
GCST90301946 |
Apolipoprotein B levels |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2778 |
4E-55 |
54.398 |
rs15285 |
0.0711 |
apolipoprotein B measurement (EFO:0004615)
|
PMID:38448586 |
GWAS725375_H |
GCST008996 |
Waist-hip ratio |
697,734 European ancestry individuals |
T |
0.2629 |
2E-9 |
8.699 |
rs15285 |
0.0117 |
waist-hip ratio (EFO:0004343)
|
PMID:30239722 |
GWAS727054_H |
GCST90302002 |
Concentration of large HDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
9E-139 |
138.046 |
rs15285 |
0.1103 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS728674_H |
GCST008733 |
Waist-to-hip ratio adjusted for BMI |
660,648 European ancestry individuals |
C |
0.74 |
4E-8 |
7.398 |
rs15285 |
0.011 |
BMI-adjusted waist-hip ratio (EFO:0007788)
|
PMID:30575882 |
GWAS729278_H |
GCST008734 |
Waist-hip ratio |
663,598 European ancestry individuals |
C |
0.74 |
5E-8 |
7.302 |
rs15285 |
N/A |
waist-hip ratio (EFO:0004343)
|
PMID:30575882 |
GWAS729775_H |
GCST90302003 |
Phospholipids in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
3E-148 |
147.523 |
rs15285 |
0.1142 |
phospholipids in large HDL measurement (EFO:0022190)
|
PMID:38448586 |
GWAS731806_H |
GCST90244926 |
1-oleoyl-2-linoleoyl-glycerol (18:1/18:2) levels |
14,296 European ancestry individuals |
T |
0.294 |
4E-27 |
26.398 |
rs15285 |
0.12077009 |
lipid measurement (EFO:0004529)
|
PMID:36357675 |
GWAS732842_H |
GCST90302036 |
Free cholesterol to total lipids ratio in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2791 |
1E-74 |
74 |
rs15285 |
0.0802 |
free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS733178_H |
GCST90301986 |
Triglycerides to total lipids ratio in IDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2779 |
2E-59 |
58.699 |
rs15285 |
0.0734 |
triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:38448586 |
GWAS733239_H |
GCST90302033 |
Cholesterol esters in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2789 |
3E-99 |
98.523 |
rs15285 |
0.0934 |
esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS733814_H |
GCST90269717 |
Cholesterol to total lipids in medium LDL percentage (UKB data field 23620) |
88,329 European ancestry individuals |
T |
0.287182 |
4E-18 |
17.398 |
rs15285 |
0.0454575 |
cholesterol to total lipids in medium LDL percentage (EFO:0022238)
|
PMID:36764567 |
GWAS734493_H |
GCST90302035 |
Free cholesterol in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2788 |
5E-79 |
78.302 |
rs15285 |
0.0829 |
free cholesterol in medium HDL measurement (EFO:0022267)
|
PMID:38448586 |
GWAS735982_H |
GCST90302031 |
Total cholesterol levels in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2789 |
6E-97 |
96.222 |
rs15285 |
0.0922 |
total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS737801_H |
GCST90301985 |
Triglycerides in IDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2777 |
1E-66 |
66 |
rs15285 |
0.0785 |
triglycerides in IDL measurement (EFO:0022149)
|
PMID:38448586 |
GWAS738206_H |
GCST90301995 |
Total cholesterol in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
8E-143 |
142.097 |
rs15285 |
0.112 |
total cholesterol change measurement (EFO:0007806) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS739360_H |
GCST90302039 |
Phospholipids in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
5E-60 |
59.302 |
rs15285 |
0.0722 |
phospholipids in medium HDL measurement (EFO:0022295)
|
PMID:38448586 |
GWAS739574_H |
GCST90301997 |
Cholesterol esters in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
1E-141 |
141 |
rs15285 |
0.1114 |
cholesterol esters in large HDL measurement (EFO:0022159)
|
PMID:38448586 |
GWAS739683_H |
GCST90302001 |
Total lipids in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
3E-141 |
140.523 |
rs15285 |
0.1113 |
total lipids in large HDL (EFO:0022189)
|
PMID:38448586 |
GWAS739931_H |
GCST90301999 |
Free cholesterol in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
3E-144 |
143.523 |
rs15285 |
0.1125 |
free cholesterol in large HDL measurement (EFO:0022157)
|
PMID:38448586 |
GWAS745044_H |
GCST90269664 |
Phospholipids in medium HDL (UKB data field 23567) |
88,329 European ancestry individuals |
T |
0.287182 |
3E-56 |
55.523 |
rs15285 |
0.0773721 |
phospholipids in medium HDL measurement (EFO:0022295)
|
PMID:36764567 |
GWAS745101_H |
GCST90269701 |
Phospholipids to total lipids in very small VLDL percentage (UKB data field 23604) |
88,329 European ancestry individuals |
T |
0.287182 |
1E-99 |
99 |
rs15285 |
0.10809 |
phospholipids:total lipids ratio (EFO:0020946)
|
PMID:36764567 |
GWAS745209_H |
GCST90269662 |
Concentration of medium HDL particles (UKB data field 23565) |
88,329 European ancestry individuals |
T |
0.287182 |
9E-78 |
77.046 |
rs15285 |
0.0902716 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:36764567 |
GWAS747580_H |
GCST007142 |
Triglycerides |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.7 |
9E-147 |
146.046 |
rs15285 |
0.116 |
triglyceride measurement (EFO:0004530)
|
PMID:29507422 |
GWAS747581_H |
GCST007142 |
Triglycerides |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.705 |
1E-17 |
17 |
rs15285 |
0.127 |
triglyceride measurement (EFO:0004530)
|
PMID:29507422 |
GWAS747582_H |
GCST007142 |
Triglycerides |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.803 |
5E-12 |
11.302 |
rs15285 |
0.126 |
triglyceride measurement (EFO:0004530)
|
PMID:29507422 |
GWAS747583_H |
GCST007142 |
Triglycerides |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
0.505 |
0.000008 |
5.097 |
rs15285 |
0.1 |
triglyceride measurement (EFO:0004530)
|
PMID:29507422 |
GWAS747584_H |
GCST007142 |
Triglycerides |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
C |
NR |
1E-177 |
177 |
rs15285 |
0.116 |
triglyceride measurement (EFO:0004530)
|
PMID:29507422 |
GWAS747852_H |
GCST90269663 |
Total lipids in medium HDL (UKB data field 23566) |
88,329 European ancestry individuals |
T |
0.287182 |
4E-69 |
68.398 |
rs15285 |
0.0855365 |
total lipids in medium HDL measurement (EFO:0022310)
|
PMID:36764567 |
GWAS760425_H |
GCST90269537 |
Apolipoprotein A1 levels (UKB data field 23440) |
88,329 European ancestry individuals |
T |
0.287182 |
4E-71 |
70.398 |
rs15285 |
0.0857633 |
apolipoprotein A 1 measurement (EFO:0004614)
|
PMID:36764567 |
GWAS760552_H |
GCST90302038 |
Concentration of medium HDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2786 |
2E-60 |
59.699 |
rs15285 |
0.0723 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS763582_H |
GCST90302037 |
Total lipids in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2787 |
1E-67 |
67 |
rs15285 |
0.0767 |
total lipids in medium HDL measurement (EFO:0022310)
|
PMID:38448586 |
GWAS767227_H |
GCST90270118 |
Multi-trait sex score |
141,980 European ancestry males |
? |
NR |
9E-83 |
82.046 |
rs15285 |
N/A |
sexual dimorphism measurement (EFO:0021796)
|
PMID:37277458 |
GWAS772423_H |
GCST90302068 |
Triglycerides to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2781 |
2E-33 |
32.699 |
rs15285 |
0.0543 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS777772_H |
GCST90302101 |
Triglycerides in small LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2775 |
2E-56 |
55.699 |
rs15285 |
0.0724 |
triglycerides in small LDL measurement (EFO:0022323)
|
PMID:38448586 |
GWAS778952_H |
GCST90302126 |
Total cholesterol levels in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2785 |
3E-66 |
65.523 |
rs15285 |
0.0757 |
total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS779592_H |
GCST90302128 |
Cholesterol esters in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2786 |
3E-59 |
58.523 |
rs15285 |
0.0713 |
esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS779969_H |
GCST90302127 |
Total cholesterol to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.279 |
6E-45 |
44.222 |
rs15285 |
0.0643 |
cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS780358_H |
GCST90302130 |
Free cholesterol in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2784 |
2E-79 |
78.699 |
rs15285 |
0.0834 |
free cholesterol in very large HDL measurement (EFO:0022273)
|
PMID:38448586 |
GWAS780809_H |
GCST90302129 |
Cholesteryl esters to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2787 |
3E-51 |
50.523 |
rs15285 |
0.0688 |
cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
None Available |
GCST90295954 |
Triglyceride to HDL cholesterol ratio |
8,158 South Asian ancestry individuals |
C |
0.744 |
4E-18 |
17.398 |
rs15285 |
0.154 |
triglyceride:HDL cholesterol ratio (EFO:0007929)
|
PMID:38200128 |
GWAS784635_H |
GCST90302133 |
Concentration of very large HDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2784 |
7E-94 |
93.155 |
rs15285 |
0.091 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS785127_H |
GCST90302060 |
Cholesteryl esters to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2786 |
1E-48 |
48 |
rs15285 |
0.0643 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS785338_H |
GCST90302135 |
Phospholipids to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2794 |
2E-84 |
83.699 |
rs15285 |
0.0857 |
phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS786228_H |
GCST90302132 |
Total lipids in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2784 |
3E-93 |
92.523 |
rs15285 |
0.0907 |
total lipids in very large HDL measurement (EFO:0022312)
|
PMID:38448586 |
GWAS789889_H |
GCST90302134 |
Phospholipids in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
T |
0.2783 |
6E-122 |
121.222 |
rs15285 |
0.1038 |
phospholipids in very large HDL measurement (EFO:0022298)
|
PMID:38448586 |
GWAS813329_H |
GCST90060511 |
Triacylglycerol_52:2_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
3E-10 |
9.523 |
rs15285 |
0.100207 |
triglyceride measurement (EFO:0004530)
|
PMID:34503513 |
GWAS813614_H |
GCST90060509 |
Triacylglycerol_52:3_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
2E-13 |
12.699 |
rs15285 |
0.116728 |
triglyceride measurement (EFO:0004530)
|
PMID:34503513 |
GWAS814766_H |
GCST90060189 |
Diacylglycerol_36:3_[M+H-H2O]1+ levels |
13,814 British ancestry individuals |
T |
NR |
3E-15 |
14.523 |
rs15285 |
0.0914561 |
diacylglycerol 36:3 measurement (EFO:0020062)
|
PMID:34503513 |
GWAS815546_H |
GCST90060240 |
Diacylglycerol_44:7_[M+H-H2O]1+ levels |
13,814 British ancestry individuals |
T |
NR |
2E-10 |
9.699 |
rs15285 |
0.0802499 |
diacylglycerol 44:7 measurement (EFO:0020069)
|
PMID:34503513 |
GWAS816514_H |
GCST90060508 |
Triacylglycerol_52:4_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
1E-11 |
11 |
rs15285 |
0.109322 |
triglyceride measurement (EFO:0004530)
|
PMID:34503513 |
None Available |
GCST90060528 |
Triacylglycerol_53:3_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
2E-10 |
9.699 |
rs15285 |
0.101737 |
triglyceride measurement (EFO:0004530)
|
PMID:34503513 |
GWAS817622_H |
GCST90060191 |
Diacylglycerol_36:2_[M+H-H2O]1+ levels |
13,814 British ancestry individuals |
T |
NR |
4E-13 |
12.398 |
rs15285 |
0.08266 |
diacylglycerol 36:2 measurement (EFO:0010355)
|
PMID:34503513 |
GWAS818234_H |
GCST90060188 |
Diacylglycerol_36:4_[M+H-H2O]1+ levels |
13,814 British ancestry individuals |
T |
NR |
6E-11 |
10.222 |
rs15285 |
0.0768112 |
diacylglycerol 36:4 measurement (EFO:0020063)
|
PMID:34503513 |
GWAS819008_H |
GCST90060178 |
Diacylglycerol_34:2_[M+H-H2O]1+ levels |
13,814 British ancestry individuals |
T |
NR |
4E-14 |
13.398 |
rs15285 |
0.0860777 |
diacylglycerol 34:2 measurement (EFO:0010353)
|
PMID:34503513 |
GWAS821016_H |
GCST90060179 |
Diacylglycerol_34:1_[M+H-H2O]1+ levels |
13,814 British ancestry individuals |
T |
NR |
2E-11 |
10.699 |
rs15285 |
0.0777581 |
diacylglycerol 34:1 measurement (EFO:0010352)
|
PMID:34503513 |
GWAS839074_H |
GCST90092866 |
Triglyceride levels in large LDL |
115,082 European ancestry individuals |
C |
0.713474 |
9E-65 |
64.046 |
rs15285 |
0.0759528 |
triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
GWAS842685_H |
GCST90060311 |
Phosphatidylcholine_34:0_[M+H]1+/Phosphatidylethanolamine_37:0_[M+H]1+/Phosphatidate_39:1_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
1E-13 |
13 |
rs15285 |
0.0942084 |
phosphatidylcholine measurement (EFO:0010226)
|
PMID:34503513 |
GWAS842980_H |
GCST90060307 |
Phosphatidylcholine_34:1_[M+H]1+/Phosphatidylethanolamine_37:1_[M+H]1+/Phosphatidate_39:2_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
1E-12 |
12 |
rs15285 |
0.0905636 |
phosphatidylcholine measurement (EFO:0010226)
|
PMID:34503513 |
None Available |
GCST90060356 |
Triacylglycerol_46:5_[M+NH4]1+ levels |
13,814 British ancestry individuals |
T |
NR |
1E-11 |
11 |
rs15285 |
0.101034 |
triglyceride measurement (EFO:0004530)
|
PMID:34503513 |
GWAS851441_H |
GCST90060284 |
Phosphatidylcholine-O_34:1_[M+H]1+/Phosphatidylcholine-P_34:0_[M+H]1+/Phosphatidylethanolamine-O_37:1_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
6E-13 |
12.222 |
rs15285 |
0.0891763 |
phosphatidylcholine measurement (EFO:0010226)
|
PMID:34503513 |
None Available |
GCST90060254 |
Phosphatidylcholine-O_32:1_[M+H]1+/Phosphatidylcholine-P_32:0_[M+H]1+/Phosphatidylethanolamine-O_35:1_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
4E-13 |
12.398 |
rs15285 |
0.0934852 |
phosphatidylcholine measurement (EFO:0010226)
|
PMID:34503513 |
None Available |
GCST90060318 |
Phosphatidylcholine-O_36:4_[M+H]1+/Phosphatidylcholine-P_36:3_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
3E-10 |
9.523 |
rs15285 |
0.0829364 |
phosphatidylcholine measurement (EFO:0010226)
|
PMID:34503513 |
GWAS853945_H |
GCST90060277 |
Phosphatidylcholine-O_34:3_[M+H]1+/Phosphatidylcholine-P_34:2_[M+H]1+/Phosphatidylethanolamine-P_37:2_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
4E-11 |
10.398 |
rs15285 |
0.0864822 |
phosphatidylcholine measurement (EFO:0010226)
|
PMID:34503513 |
GWAS869662_H |
GCST90315311 |
LDLR/PCSK9 protein level ratio |
43,509 European ancestry individuals |
? |
NR |
1E-51 |
51 |
rs15285 |
0.114377 |
blood protein measurement (EFO:0007937)
|
PMID:38412862 |
GWAS888773_H |
GCST90092808 |
Apolipoprotein A1 levels |
115,082 European ancestry individuals |
C |
0.713474 |
1E-85 |
85 |
rs15285 |
0.0819345 |
apolipoprotein A 1 measurement (EFO:0004614)
|
PMID:35213538 |
GWAS890150_H |
GCST90092826 |
Concentration of HDL particles |
115,082 European ancestry individuals |
C |
0.713474 |
4E-81 |
80.398 |
rs15285 |
0.081838 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
None Available |
GCST90092824 |
Free cholesterol levels in HDL |
115,082 European ancestry individuals |
C |
0.713474 |
1E-96 |
96 |
rs15285 |
0.0843391 |
free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS890805_H |
GCST90092825 |
Total lipid levels in HDL |
115,082 European ancestry individuals |
C |
0.713474 |
5E-98 |
97.302 |
rs15285 |
0.0861023 |
lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS906333_H |
GCST90092905 |
Cholesterol to total lipids ratio in medium LDL |
115,082 European ancestry individuals |
C |
0.713474 |
1E-21 |
21 |
rs15285 |
0.0438072 |
cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
None Available |
GCST90060241 |
Sphingomyelin_34:0_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
2E-10 |
9.699 |
rs15285 |
0.0802202 |
sphingomyelin measurement (EFO:0010118)
|
PMID:34503513 |
GWAS916802_H |
GCST90060235 |
Sphingomyelin_34:2_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
5E-11 |
10.302 |
rs15285 |
0.0788278 |
sphingomyelin measurement (EFO:0010118)
|
PMID:34503513 |
None Available |
GCST90060352 |
Sphingomyelin_40:2_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
1E-11 |
11 |
rs15285 |
0.101008 |
sphingomyelin measurement (EFO:0010118)
|
PMID:34503513 |
GWAS918157_H |
GCST90092827 |
Phospholipid levels in HDL |
115,082 European ancestry individuals |
C |
0.713474 |
3E-86 |
85.523 |
rs15285 |
0.0811327 |
phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
None Available |
GCST90060306 |
Sphingomyelin_38:1_[M+H]1+ levels |
13,814 British ancestry individuals |
T |
NR |
4E-14 |
13.398 |
rs15285 |
0.0962112 |
sphingomyelin measurement (EFO:0010118)
|
PMID:34503513 |
GWAS925128_H |
GCST90092898 |
Total lipid levels in medium HDL |
115,082 European ancestry individuals |
C |
0.713474 |
4E-83 |
82.398 |
rs15285 |
0.0817955 |
lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS929253_H |
GCST90092896 |
Free cholesterol levels in medium HDL |
115,082 European ancestry individuals |
C |
0.713474 |
7E-99 |
98.155 |
rs15285 |
0.0876187 |
free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS929349_H |
GCST90092894 |
Cholesteryl ester levels in medium HDL |
115,082 European ancestry individuals |
C |
0.713474 |
4E-137 |
136.398 |
rs15285 |
0.105123 |
cholesteryl ester measurement (EFO:0010351) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS929472_H |
GCST90239654 |
High density lipoprotein cholesterol levels |
40,963 South Asian ancestry individuals |
T |
0.248643 |
1E-43 |
43 |
rs15285 |
0.116966 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34887591 |
GWAS929597_H |
GCST90092900 |
Phospholipid levels in medium HDL |
115,082 European ancestry individuals |
C |
0.713474 |
9E-67 |
66.046 |
rs15285 |
0.0736177 |
phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS942011_H |
GCST90239652 |
High density lipoprotein cholesterol levels |
1,320,016 European ancestry individuals |
T |
0.286591 |
5E-632 |
631.302 |
rs15285 |
0.107166 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34887591 |
GWAS959602_H |
GCST90093049 |
Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL |
111,638 European ancestry individuals |
C |
0.7143 |
1E-55 |
55 |
rs15285 |
0.0719734 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:35213538 |
GWAS960227_H |
GCST90092892 |
Cholesterol levels in medium HDL |
115,082 European ancestry individuals |
C |
0.713474 |
2E-130 |
129.699 |
rs15285 |
0.10211 |
total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS968491_H |
GCST90092899 |
Concentration of medium HDL particles |
115,082 European ancestry individuals |
C |
0.713474 |
6E-94 |
93.222 |
rs15285 |
0.0864395 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS978549_H |
GCST90092990 |
Total concentration of lipoprotein particles |
115,082 European ancestry individuals |
C |
0.713474 |
4E-65 |
64.398 |
rs15285 |
0.073236 |
lipoprotein measurement (EFO:0004732)
|
PMID:35213538 |
GWAS979851_H |
GCST90239670 |
Non-HDL cholesterol levels |
1,320,016 European ancestry individuals |
T |
0.285168 |
2E-88 |
87.699 |
rs15285 |
0.0422277 |
non-high density lipoprotein cholesterol measurement (EFO:0005689)
|
PMID:34887591 |
GWAS981584_H |
GCST90093037 |
Phospholipids to total lipids ratio in very small VLDL |
115,082 European ancestry individuals |
C |
0.713474 |
9E-126 |
125.046 |
rs15285 |
0.106196 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:35213538 |
GWAS982898_H |
GCST90018956 |
HDL cholesterol |
315,133 European ancestry individuals, 74,970 East Asian ancestry individuals |
T |
NR |
3E-576 |
575.523 |
rs15285 |
0.1194 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34594039 |
None Available |
GCST90451699 |
Type 2 diabetes mellitus adjusted for BMI or coronary artery disease (pleiotropy) |
50,409 European ancestry type 2 diabetes adjusted for BMI cases, 181,522 European ancestry coronary artery disease cases, 1,508,065 European ancestry controls |
? |
NR |
3E-21 |
20.523 |
rs15285 |
N/A |
coronary artery disease (EFO:0001645)
|
PMID:38062574 |
None Available |
GCST90091702 |
Postprandial cholesterol esters in medium HDL |
null |
T |
0.299172533 |
8E-15 |
14.097 |
rs15285 |
0.182657 |
esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091703 |
Postprandial free cholesterol in medium HDL |
null |
T |
0.299172533 |
1E-14 |
14 |
rs15285 |
0.182135 |
free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091704 |
Postprandial total lipids in medium HDL |
null |
T |
0.299172533 |
2E-12 |
11.699 |
rs15285 |
0.165938 |
lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091705 |
Postprandial medium HDL particle concentration |
null |
T |
0.299172533 |
1E-11 |
11 |
rs15285 |
0.160245 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091566 |
Fasting phospholipid levels in medium HDL |
null |
T |
0.298856083 |
1E-8 |
8 |
rs15285 |
0.128135 |
phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091565 |
Fasting medium HDL particle concentration |
null |
T |
0.298856083 |
1E-8 |
8 |
rs15285 |
0.128381 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091706 |
Postprandial phospholipid levels in medium HDL |
null |
T |
0.299172533 |
5E-12 |
11.302 |
rs15285 |
0.162458 |
phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091701 |
Postprandial total cholesterol in medium HDL |
null |
T |
0.299172533 |
7E-15 |
14.155 |
rs15285 |
0.183179 |
high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90292529 |
Total cholesterol levels (MTAG) |
125,000 African ancestry individuals (MTAG boosted by high-density lipoprotein and triglyceride samples) |
C |
NR |
2E-8 |
7.699 |
rs15285 |
0.019 |
total cholesterol measurement (EFO:0004574)
|
PMID:37669986 |
None Available |
GCST90091649 |
Postprandial apolipoprotein A-I |
null |
T |
0.299103726 |
2E-8 |
7.699 |
rs15285 |
0.132809 |
apolipoprotein A 1 measurement (EFO:0004614)
|
PMID:34610981 |
None Available |
GCST90091563 |
Fasting free cholesterol in medium HDL |
null |
T |
0.298856083 |
8E-11 |
10.097 |
rs15285 |
0.146642 |
free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90091564 |
Fasting total lipids in medium HDL |
null |
T |
0.298856083 |
3E-9 |
8.523 |
rs15285 |
0.133507 |
lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:34610981 |
None Available |
GCST90448633 |
Triglyceride levels |
38,000 South Asian ancestry individuals |
T |
NR |
3E-72 |
71.523 |
rs15285 |
0.155 |
triglyceride measurement (EFO:0004530)
|
PMID:39414775 |