Vertebrate Trait Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | GWAS929349_H | Human | blood lipid amount | | IAGP | rs15285 | 405850206 | Based on the EFO term ID | GWAS_CATALOG | PMID:35213538 | |
|
Vertebrate Trait Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | GWAS929349_H | Human | blood lipid amount | | IAGP | rs15285 | 405850206 | Based on the EFO term ID | GWAS_CATALOG | PMID:35213538 | |
|
# | Reference Title | Reference Citation |
1. | RGD GWAS Catalog Import Pipeline | RGD pipeline to import data from GWAS Catalog and create human variant and QTL records |
The following Genes overlap with this region. | Full Report | CSV | TAB | Printer | Analysis Tools |
Peak: (rs15285) |
|
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
Data has come from the GWAS Catalog | ||
The highlighted row represents the current QTL |
QTL | GWAS Catalog Study | Disease Trait | Study Size | Risk Allele | Risk Allele Frequency | P Value | P Value MLOG | Peak Marker | Reported Odds Ratio or Beta-coefficient | Ontology Accession | PubMed |
GWAS547365_H | GCST007140 | High density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.7 | 1E-110 | 110 | rs15285 | 0.091 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29507422 |
GWAS547366_H | GCST007140 | High density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.705 | 1E-16 | 16 | rs15285 | 0.111 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29507422 |
GWAS547367_H | GCST007140 | High density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.803 | 1E-10 | 10 | rs15285 | 0.109 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29507422 |
GWAS547368_H | GCST007140 | High density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | NR | 3E-139 | 138.523 | rs15285 | 0.094 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29507422 |
GWAS573444_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-14 | 14 | rs15285 | 0.08341065 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577744_H | GCST010173 | Triglyceride levels | 324,694 British ancestry individuals | ? | NR | 2E-459 | 458.699 | rs15285 | 0.1223 | triglyceride measurement (EFO:0004530) |
PMID:32154731 |
GWAS580234_H | GCST009368 | HDL cholesterol levels x long total sleep time interaction (2df test) | 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls | ? | NR | 7E-126 | 125.155 | rs15285 | 0.02406 | sleep duration (EFO:0005271) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:31719535 |
GWAS607214_H | GCST004207 | HDL cholesterol | 19,223 British ancestry individuals from 6863 families. | T | 0.2675 | 1E-18 | 18 | rs15285 | 0.109238155 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:28270201 |
GWAS633496_H | GCST008035 | High density lipoprotein cholesterol levels | 10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals | ? | NR | 5E-40 | 39.302 | rs15285 | 1.587487 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:31217584 |
GWAS641486_H | GCST008046 | Triglyceride levels | 9,980 African American individuals, 17,856 Hispanic/Latino individuals, 2,381 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 360 individuals | ? | NR | 6E-40 | 39.222 | rs15285 | 0.05650247 | triglyceride measurement (EFO:0004530) |
PMID:31217584 |
GWAS649217_H | GCST90132304 | Coronary artery disease | 27,021 African American or Afro-Caribbean cases, 102,305 African American or Afro-Caribbean controls | ? | NR | 5E-9 | 8.302 | rs15285 | 0.0593 | coronary artery disease (EFO:0001645) |
PMID:35915156 |
GWAS658662_H | GCST009450 | Parental longevity (father's age at death or father's attained age) | up to 699,000 European ancestry individuals | G | NR | 8E-10 | 9.097 | rs15285 | N/A | parental longevity (EFO:0007796) |
PMID:31484785 |
GWAS663408_H | GCST007931 | Medication use (HMG CoA reductase inhibitors) | 73,475 European ancestry cases, 216,910 European ancestry controls | T | 0.28486 | 3E-21 | 20.523 | rs15285 | 0.058676165 | HMG CoA reductase inhibitor use measurement (EFO:0009932) |
PMID:31015401 |
GWAS672344_H | GCST90269667 | Free cholesterol in medium HDL (UKB data field 23570) | 88,329 European ancestry individuals | T | 0.287182 | 2E-81 | 80.699 | rs15285 | 0.0914045 | free cholesterol in medium HDL measurement (EFO:0022267) |
PMID:36764567 |
GWAS672570_H | GCST90269666 | Cholesteryl esters in medium HDL (UKB data field 23569) | 88,329 European ancestry individuals | T | 0.287182 | 7E-111 | 110.155 | rs15285 | 0.108596 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS673022_H | GCST90269665 | Cholesterol in medium HDL (UKB data field 23568) | 88,329 European ancestry individuals | T | 0.287182 | 8E-106 | 105.097 | rs15285 | 0.105676 | cholesterol in medium HDL measurement (EFO:0021903) |
PMID:36764567 |
None Available | GCST001004 | Triglycerides-Blood Pressure (TG-BP) | 22,161 European ancestry individuals | A | NR | 1E-10 | 10 | rs15285 | 0.27 | triglyceride measurement (EFO:0004530) blood pressure (EFO:0004325) |
PMID:21386085 |
GWAS680175_H | GCST90269527 | Concentration of HDL particles (UKB data field 23430) | 88,329 European ancestry individuals | T | 0.287182 | 6E-67 | 66.222 | rs15285 | 0.0850471 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:36764567 |
GWAS681734_H | GCST90269523 | Total lipids in HDL (UKB data field 23426) | 88,329 European ancestry individuals | T | 0.287182 | 2E-80 | 79.699 | rs15285 | 0.0899288 | total lipids in HDL measurement (EFO:0022307) |
PMID:36764567 |
GWAS683638_H | GCST90277415 | Triacylglycerol (58:7) levels | 5,403 Finnish ancestry individuals | T | 0.261072 | 2E-8 | 7.699 | rs15285 | 0.123238 | triacylglycerol 58:7 measurement (EFO:0010441) |
PMID:37907536 |
None Available | GCST90277402 | Triacylglycerol (53:3) levels | 7,113 Finnish ancestry individuals | T | 0.261072 | 5E-9 | 8.302 | rs15285 | 0.111495 | PMID:37907536 | |
GWAS686556_H | GCST90269511 | Phospholipids in HDL (UKB data field 23414) | 88,329 European ancestry individuals | T | 0.287182 | 1E-71 | 71 | rs15285 | 0.0850499 | phospholipids in HDL measurement (EFO:0022293) |
PMID:36764567 |
GWAS690276_H | GCST90277394 | Triacylglycerol (51:3) levels | 7,119 Finnish ancestry individuals | T | 0.261072 | 3E-8 | 7.523 | rs15285 | 0.105751 | PMID:37907536 | |
None Available | GCST90277396 | Triacylglycerol (52:2) levels | 7,168 Finnish ancestry individuals | T | 0.261072 | 2E-8 | 7.699 | rs15285 | 0.106116 | triacylglycerol 52:2 measurement (EFO:0010414) |
PMID:37907536 |
GWAS690840_H | GCST90269633 | Triglycerides in large LDL (UKB data field 23536) | 88,329 European ancestry individuals | T | 0.287182 | 2E-49 | 48.699 | rs15285 | 0.076103 | triglycerides in large LDL measurement (EFO:0022319) |
PMID:36764567 |
GWAS699409_H | GCST90302113 | Phospholipids to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 1E-96 | 96 | rs15285 | 0.0921 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS706338_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 9E-12 | 11.046 | rs15285 | 0.08500996 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS711706_H | GCST90301971 | Total cholesterol levels in HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 3E-150 | 149.523 | rs15285 | 0.1149 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS711841_H | GCST90301969 | Total cholesterol in HDL2 | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 9E-161 | 160.046 | rs15285 | 0.1188 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS713628_H | GCST90301972 | Mean diameter of HDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 3E-129 | 128.523 | rs15285 | 0.1065 | high density lipoprotein particle size measurement (EFO:0008592) |
PMID:38448586 |
GWAS716334_H | GCST005194 | Coronary artery disease | 34,541 cases, 261,984 controls | T | 0.29 | 8E-14 | 13.097 | rs15285 | 0.052 | coronary artery disease (EFO:0001645) |
PMID:29212778 |
GWAS721065_H | GCST90301945 | Apolipoprotein A-I levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2787 | 1E-72 | 72 | rs15285 | 0.0791 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:38448586 |
GWAS721895_H | GCST90301947 | Ratio of apolipoprotein B to apolipoprotein A1 levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2776 | 3E-132 | 131.523 | rs15285 | 0.1117 | apolipoprotein A 1 measurement (EFO:0004614) apolipoprotein B measurement (EFO:0004615) |
PMID:38448586 |
GWAS722685_H | GCST90301946 | Apolipoprotein B levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2778 | 4E-55 | 54.398 | rs15285 | 0.0711 | apolipoprotein B measurement (EFO:0004615) |
PMID:38448586 |
GWAS725375_H | GCST008996 | Waist-hip ratio | 697,734 European ancestry individuals | T | 0.2629 | 2E-9 | 8.699 | rs15285 | 0.0117 | waist-hip ratio (EFO:0004343) |
PMID:30239722 |
GWAS727054_H | GCST90302002 | Concentration of large HDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 9E-139 | 138.046 | rs15285 | 0.1103 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS728674_H | GCST008733 | Waist-to-hip ratio adjusted for BMI | 660,648 European ancestry individuals | C | 0.74 | 4E-8 | 7.398 | rs15285 | 0.011 | BMI-adjusted waist-hip ratio (EFO:0007788) |
PMID:30575882 |
GWAS729278_H | GCST008734 | Waist-hip ratio | 663,598 European ancestry individuals | C | 0.74 | 5E-8 | 7.302 | rs15285 | N/A | waist-hip ratio (EFO:0004343) |
PMID:30575882 |
GWAS729775_H | GCST90302003 | Phospholipids in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 3E-148 | 147.523 | rs15285 | 0.1142 | phospholipids in large HDL measurement (EFO:0022190) |
PMID:38448586 |
GWAS731806_H | GCST90244926 | 1-oleoyl-2-linoleoyl-glycerol (18:1/18:2) levels | 14,296 European ancestry individuals | T | 0.294 | 4E-27 | 26.398 | rs15285 | 0.12077009 | lipid measurement (EFO:0004529) |
PMID:36357675 |
GWAS732842_H | GCST90302036 | Free cholesterol to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2791 | 1E-74 | 74 | rs15285 | 0.0802 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS733178_H | GCST90301986 | Triglycerides to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2779 | 2E-59 | 58.699 | rs15285 | 0.0734 | triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS733239_H | GCST90302033 | Cholesterol esters in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2789 | 3E-99 | 98.523 | rs15285 | 0.0934 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS733814_H | GCST90269717 | Cholesterol to total lipids in medium LDL percentage (UKB data field 23620) | 88,329 European ancestry individuals | T | 0.287182 | 4E-18 | 17.398 | rs15285 | 0.0454575 | cholesterol to total lipids in medium LDL percentage (EFO:0022238) |
PMID:36764567 |
GWAS734493_H | GCST90302035 | Free cholesterol in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2788 | 5E-79 | 78.302 | rs15285 | 0.0829 | free cholesterol in medium HDL measurement (EFO:0022267) |
PMID:38448586 |
GWAS735982_H | GCST90302031 | Total cholesterol levels in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2789 | 6E-97 | 96.222 | rs15285 | 0.0922 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS737801_H | GCST90301985 | Triglycerides in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2777 | 1E-66 | 66 | rs15285 | 0.0785 | triglycerides in IDL measurement (EFO:0022149) |
PMID:38448586 |
GWAS738206_H | GCST90301995 | Total cholesterol in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 8E-143 | 142.097 | rs15285 | 0.112 | total cholesterol change measurement (EFO:0007806) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS739360_H | GCST90302039 | Phospholipids in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 5E-60 | 59.302 | rs15285 | 0.0722 | phospholipids in medium HDL measurement (EFO:0022295) |
PMID:38448586 |
GWAS739574_H | GCST90301997 | Cholesterol esters in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 1E-141 | 141 | rs15285 | 0.1114 | cholesterol esters in large HDL measurement (EFO:0022159) |
PMID:38448586 |
GWAS739683_H | GCST90302001 | Total lipids in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 3E-141 | 140.523 | rs15285 | 0.1113 | total lipids in large HDL (EFO:0022189) |
PMID:38448586 |
GWAS739931_H | GCST90301999 | Free cholesterol in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 3E-144 | 143.523 | rs15285 | 0.1125 | free cholesterol in large HDL measurement (EFO:0022157) |
PMID:38448586 |
GWAS745044_H | GCST90269664 | Phospholipids in medium HDL (UKB data field 23567) | 88,329 European ancestry individuals | T | 0.287182 | 3E-56 | 55.523 | rs15285 | 0.0773721 | phospholipids in medium HDL measurement (EFO:0022295) |
PMID:36764567 |
GWAS745101_H | GCST90269701 | Phospholipids to total lipids in very small VLDL percentage (UKB data field 23604) | 88,329 European ancestry individuals | T | 0.287182 | 1E-99 | 99 | rs15285 | 0.10809 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS745209_H | GCST90269662 | Concentration of medium HDL particles (UKB data field 23565) | 88,329 European ancestry individuals | T | 0.287182 | 9E-78 | 77.046 | rs15285 | 0.0902716 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:36764567 |
GWAS747580_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.7 | 9E-147 | 146.046 | rs15285 | 0.116 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS747581_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.705 | 1E-17 | 17 | rs15285 | 0.127 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS747582_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.803 | 5E-12 | 11.302 | rs15285 | 0.126 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS747583_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | 0.505 | 0.000008 | 5.097 | rs15285 | 0.1 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS747584_H | GCST007142 | Triglycerides | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | C | NR | 1E-177 | 177 | rs15285 | 0.116 | triglyceride measurement (EFO:0004530) |
PMID:29507422 |
GWAS747852_H | GCST90269663 | Total lipids in medium HDL (UKB data field 23566) | 88,329 European ancestry individuals | T | 0.287182 | 4E-69 | 68.398 | rs15285 | 0.0855365 | total lipids in medium HDL measurement (EFO:0022310) |
PMID:36764567 |
GWAS760425_H | GCST90269537 | Apolipoprotein A1 levels (UKB data field 23440) | 88,329 European ancestry individuals | T | 0.287182 | 4E-71 | 70.398 | rs15285 | 0.0857633 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:36764567 |
GWAS760552_H | GCST90302038 | Concentration of medium HDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2786 | 2E-60 | 59.699 | rs15285 | 0.0723 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS763582_H | GCST90302037 | Total lipids in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2787 | 1E-67 | 67 | rs15285 | 0.0767 | total lipids in medium HDL measurement (EFO:0022310) |
PMID:38448586 |
GWAS767227_H | GCST90270118 | Multi-trait sex score | 141,980 European ancestry males | ? | NR | 9E-83 | 82.046 | rs15285 | N/A | sexual dimorphism measurement (EFO:0021796) |
PMID:37277458 |
GWAS772423_H | GCST90302068 | Triglycerides to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2781 | 2E-33 | 32.699 | rs15285 | 0.0543 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS777772_H | GCST90302101 | Triglycerides in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2775 | 2E-56 | 55.699 | rs15285 | 0.0724 | triglycerides in small LDL measurement (EFO:0022323) |
PMID:38448586 |
GWAS778952_H | GCST90302126 | Total cholesterol levels in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2785 | 3E-66 | 65.523 | rs15285 | 0.0757 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS779592_H | GCST90302128 | Cholesterol esters in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2786 | 3E-59 | 58.523 | rs15285 | 0.0713 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS779969_H | GCST90302127 | Total cholesterol to total lipids ratio in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.279 | 6E-45 | 44.222 | rs15285 | 0.0643 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS780358_H | GCST90302130 | Free cholesterol in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2784 | 2E-79 | 78.699 | rs15285 | 0.0834 | free cholesterol in very large HDL measurement (EFO:0022273) |
PMID:38448586 |
GWAS780809_H | GCST90302129 | Cholesteryl esters to total lipids ratio in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2787 | 3E-51 | 50.523 | rs15285 | 0.0688 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90295954 | Triglyceride to HDL cholesterol ratio | 8,158 South Asian ancestry individuals | C | 0.744 | 4E-18 | 17.398 | rs15285 | 0.154 | triglyceride:HDL cholesterol ratio (EFO:0007929) |
PMID:38200128 |
GWAS784635_H | GCST90302133 | Concentration of very large HDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2784 | 7E-94 | 93.155 | rs15285 | 0.091 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS785127_H | GCST90302060 | Cholesteryl esters to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2786 | 1E-48 | 48 | rs15285 | 0.0643 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS785338_H | GCST90302135 | Phospholipids to total lipids ratio in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2794 | 2E-84 | 83.699 | rs15285 | 0.0857 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS786228_H | GCST90302132 | Total lipids in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2784 | 3E-93 | 92.523 | rs15285 | 0.0907 | total lipids in very large HDL measurement (EFO:0022312) |
PMID:38448586 |
GWAS789889_H | GCST90302134 | Phospholipids in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.2783 | 6E-122 | 121.222 | rs15285 | 0.1038 | phospholipids in very large HDL measurement (EFO:0022298) |
PMID:38448586 |
GWAS813329_H | GCST90060511 | Triacylglycerol_52:2_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 3E-10 | 9.523 | rs15285 | 0.100207 | triglyceride measurement (EFO:0004530) |
PMID:34503513 |
GWAS813614_H | GCST90060509 | Triacylglycerol_52:3_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 2E-13 | 12.699 | rs15285 | 0.116728 | triglyceride measurement (EFO:0004530) |
PMID:34503513 |
GWAS814766_H | GCST90060189 | Diacylglycerol_36:3_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 3E-15 | 14.523 | rs15285 | 0.0914561 | diacylglycerol 36:3 measurement (EFO:0020062) |
PMID:34503513 |
GWAS815546_H | GCST90060240 | Diacylglycerol_44:7_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 2E-10 | 9.699 | rs15285 | 0.0802499 | diacylglycerol 44:7 measurement (EFO:0020069) |
PMID:34503513 |
GWAS816514_H | GCST90060508 | Triacylglycerol_52:4_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 1E-11 | 11 | rs15285 | 0.109322 | triglyceride measurement (EFO:0004530) |
PMID:34503513 |
None Available | GCST90060528 | Triacylglycerol_53:3_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 2E-10 | 9.699 | rs15285 | 0.101737 | triglyceride measurement (EFO:0004530) |
PMID:34503513 |
GWAS817622_H | GCST90060191 | Diacylglycerol_36:2_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 4E-13 | 12.398 | rs15285 | 0.08266 | diacylglycerol 36:2 measurement (EFO:0010355) |
PMID:34503513 |
GWAS818234_H | GCST90060188 | Diacylglycerol_36:4_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 6E-11 | 10.222 | rs15285 | 0.0768112 | diacylglycerol 36:4 measurement (EFO:0020063) |
PMID:34503513 |
GWAS819008_H | GCST90060178 | Diacylglycerol_34:2_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 4E-14 | 13.398 | rs15285 | 0.0860777 | diacylglycerol 34:2 measurement (EFO:0010353) |
PMID:34503513 |
GWAS821016_H | GCST90060179 | Diacylglycerol_34:1_[M+H-H2O]1+ levels | 13,814 British ancestry individuals | T | NR | 2E-11 | 10.699 | rs15285 | 0.0777581 | diacylglycerol 34:1 measurement (EFO:0010352) |
PMID:34503513 |
GWAS839074_H | GCST90092866 | Triglyceride levels in large LDL | 115,082 European ancestry individuals | C | 0.713474 | 9E-65 | 64.046 | rs15285 | 0.0759528 | triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS842685_H | GCST90060311 | Phosphatidylcholine_34:0_[M+H]1+/Phosphatidylethanolamine_37:0_[M+H]1+/Phosphatidate_39:1_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 1E-13 | 13 | rs15285 | 0.0942084 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
GWAS842980_H | GCST90060307 | Phosphatidylcholine_34:1_[M+H]1+/Phosphatidylethanolamine_37:1_[M+H]1+/Phosphatidate_39:2_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 1E-12 | 12 | rs15285 | 0.0905636 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
None Available | GCST90060356 | Triacylglycerol_46:5_[M+NH4]1+ levels | 13,814 British ancestry individuals | T | NR | 1E-11 | 11 | rs15285 | 0.101034 | triglyceride measurement (EFO:0004530) |
PMID:34503513 |
GWAS851441_H | GCST90060284 | Phosphatidylcholine-O_34:1_[M+H]1+/Phosphatidylcholine-P_34:0_[M+H]1+/Phosphatidylethanolamine-O_37:1_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 6E-13 | 12.222 | rs15285 | 0.0891763 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
None Available | GCST90060254 | Phosphatidylcholine-O_32:1_[M+H]1+/Phosphatidylcholine-P_32:0_[M+H]1+/Phosphatidylethanolamine-O_35:1_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 4E-13 | 12.398 | rs15285 | 0.0934852 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
None Available | GCST90060318 | Phosphatidylcholine-O_36:4_[M+H]1+/Phosphatidylcholine-P_36:3_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 3E-10 | 9.523 | rs15285 | 0.0829364 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
GWAS853945_H | GCST90060277 | Phosphatidylcholine-O_34:3_[M+H]1+/Phosphatidylcholine-P_34:2_[M+H]1+/Phosphatidylethanolamine-P_37:2_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 4E-11 | 10.398 | rs15285 | 0.0864822 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
GWAS869662_H | GCST90315311 | LDLR/PCSK9 protein level ratio | 43,509 European ancestry individuals | ? | NR | 1E-51 | 51 | rs15285 | 0.114377 | blood protein measurement (EFO:0007937) |
PMID:38412862 |
GWAS888773_H | GCST90092808 | Apolipoprotein A1 levels | 115,082 European ancestry individuals | C | 0.713474 | 1E-85 | 85 | rs15285 | 0.0819345 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:35213538 |
GWAS890150_H | GCST90092826 | Concentration of HDL particles | 115,082 European ancestry individuals | C | 0.713474 | 4E-81 | 80.398 | rs15285 | 0.081838 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092824 | Free cholesterol levels in HDL | 115,082 European ancestry individuals | C | 0.713474 | 1E-96 | 96 | rs15285 | 0.0843391 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS890805_H | GCST90092825 | Total lipid levels in HDL | 115,082 European ancestry individuals | C | 0.713474 | 5E-98 | 97.302 | rs15285 | 0.0861023 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS906333_H | GCST90092905 | Cholesterol to total lipids ratio in medium LDL | 115,082 European ancestry individuals | C | 0.713474 | 1E-21 | 21 | rs15285 | 0.0438072 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90060241 | Sphingomyelin_34:0_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 2E-10 | 9.699 | rs15285 | 0.0802202 | sphingomyelin measurement (EFO:0010118) |
PMID:34503513 |
GWAS916802_H | GCST90060235 | Sphingomyelin_34:2_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 5E-11 | 10.302 | rs15285 | 0.0788278 | sphingomyelin measurement (EFO:0010118) |
PMID:34503513 |
None Available | GCST90060352 | Sphingomyelin_40:2_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 1E-11 | 11 | rs15285 | 0.101008 | sphingomyelin measurement (EFO:0010118) |
PMID:34503513 |
GWAS918157_H | GCST90092827 | Phospholipid levels in HDL | 115,082 European ancestry individuals | C | 0.713474 | 3E-86 | 85.523 | rs15285 | 0.0811327 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90060306 | Sphingomyelin_38:1_[M+H]1+ levels | 13,814 British ancestry individuals | T | NR | 4E-14 | 13.398 | rs15285 | 0.0962112 | sphingomyelin measurement (EFO:0010118) |
PMID:34503513 |
GWAS925128_H | GCST90092898 | Total lipid levels in medium HDL | 115,082 European ancestry individuals | C | 0.713474 | 4E-83 | 82.398 | rs15285 | 0.0817955 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS929253_H | GCST90092896 | Free cholesterol levels in medium HDL | 115,082 European ancestry individuals | C | 0.713474 | 7E-99 | 98.155 | rs15285 | 0.0876187 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS929349_H | GCST90092894 | Cholesteryl ester levels in medium HDL | 115,082 European ancestry individuals | C | 0.713474 | 4E-137 | 136.398 | rs15285 | 0.105123 | cholesteryl ester measurement (EFO:0010351) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS929472_H | GCST90239654 | High density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals | T | 0.248643 | 1E-43 | 43 | rs15285 | 0.116966 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34887591 |
GWAS929597_H | GCST90092900 | Phospholipid levels in medium HDL | 115,082 European ancestry individuals | C | 0.713474 | 9E-67 | 66.046 | rs15285 | 0.0736177 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS942011_H | GCST90239652 | High density lipoprotein cholesterol levels | 1,320,016 European ancestry individuals | T | 0.286591 | 5E-632 | 631.302 | rs15285 | 0.107166 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34887591 |
GWAS959602_H | GCST90093049 | Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL | 111,638 European ancestry individuals | C | 0.7143 | 1E-55 | 55 | rs15285 | 0.0719734 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS960227_H | GCST90092892 | Cholesterol levels in medium HDL | 115,082 European ancestry individuals | C | 0.713474 | 2E-130 | 129.699 | rs15285 | 0.10211 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS968491_H | GCST90092899 | Concentration of medium HDL particles | 115,082 European ancestry individuals | C | 0.713474 | 6E-94 | 93.222 | rs15285 | 0.0864395 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS978549_H | GCST90092990 | Total concentration of lipoprotein particles | 115,082 European ancestry individuals | C | 0.713474 | 4E-65 | 64.398 | rs15285 | 0.073236 | lipoprotein measurement (EFO:0004732) |
PMID:35213538 |
GWAS979851_H | GCST90239670 | Non-HDL cholesterol levels | 1,320,016 European ancestry individuals | T | 0.285168 | 2E-88 | 87.699 | rs15285 | 0.0422277 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS981584_H | GCST90093037 | Phospholipids to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | C | 0.713474 | 9E-126 | 125.046 | rs15285 | 0.106196 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS982898_H | GCST90018956 | HDL cholesterol | 315,133 European ancestry individuals, 74,970 East Asian ancestry individuals | T | NR | 3E-576 | 575.523 | rs15285 | 0.1194 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34594039 |
None Available | GCST90451699 | Type 2 diabetes mellitus adjusted for BMI or coronary artery disease (pleiotropy) | 50,409 European ancestry type 2 diabetes adjusted for BMI cases, 181,522 European ancestry coronary artery disease cases, 1,508,065 European ancestry controls | ? | NR | 3E-21 | 20.523 | rs15285 | N/A | coronary artery disease (EFO:0001645) |
PMID:38062574 |
None Available | GCST90091702 | Postprandial cholesterol esters in medium HDL | null | T | 0.299172533 | 8E-15 | 14.097 | rs15285 | 0.182657 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091703 | Postprandial free cholesterol in medium HDL | null | T | 0.299172533 | 1E-14 | 14 | rs15285 | 0.182135 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091704 | Postprandial total lipids in medium HDL | null | T | 0.299172533 | 2E-12 | 11.699 | rs15285 | 0.165938 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091705 | Postprandial medium HDL particle concentration | null | T | 0.299172533 | 1E-11 | 11 | rs15285 | 0.160245 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091566 | Fasting phospholipid levels in medium HDL | null | T | 0.298856083 | 1E-8 | 8 | rs15285 | 0.128135 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091565 | Fasting medium HDL particle concentration | null | T | 0.298856083 | 1E-8 | 8 | rs15285 | 0.128381 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091706 | Postprandial phospholipid levels in medium HDL | null | T | 0.299172533 | 5E-12 | 11.302 | rs15285 | 0.162458 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091701 | Postprandial total cholesterol in medium HDL | null | T | 0.299172533 | 7E-15 | 14.155 | rs15285 | 0.183179 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90292529 | Total cholesterol levels (MTAG) | 125,000 African ancestry individuals (MTAG boosted by high-density lipoprotein and triglyceride samples) | C | NR | 2E-8 | 7.699 | rs15285 | 0.019 | total cholesterol measurement (EFO:0004574) |
PMID:37669986 |
None Available | GCST90091649 | Postprandial apolipoprotein A-I | null | T | 0.299103726 | 2E-8 | 7.699 | rs15285 | 0.132809 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:34610981 |
None Available | GCST90091563 | Fasting free cholesterol in medium HDL | null | T | 0.298856083 | 8E-11 | 10.097 | rs15285 | 0.146642 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90091564 | Fasting total lipids in medium HDL | null | T | 0.298856083 | 3E-9 | 8.523 | rs15285 | 0.133507 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:34610981 |
None Available | GCST90448633 | Triglyceride levels | 38,000 South Asian ancestry individuals | T | NR | 3E-72 | 71.523 | rs15285 | 0.155 | triglyceride measurement (EFO:0004530) |
PMID:39414775 |
Note Type | Note | Reference |
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