GWAS980701_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS980701_H (very low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS980701 (human)) Homo sapiens

Symbol: GWAS980701_H
Name: very low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS980701 (human)
RGD ID: 407331725
Trait: very low density lipoprotein cholesterol measurement, phospholipid measurement
Measurement Type: blood very low density lipoprotein cholesterol level   (CMO:0000648)    
LOD Score: Not Available
P Value: 4.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,680,500 - 58,680,501RGD_MAPPER_PIPELINEGRCh38
GRCh371558,972,699 - 58,972,700RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS980701_HHumanblood very low density lipoprotein cholesterol level  IAGPrs80236739405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS980701_HHumanphospholipid measurement  IAGPrs80236739405850206 GWAS_CATALOGPMID:35213538
GWAS980701_HHumanvery low density lipoprotein cholesterol measurement  IAGPrs80236739405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
735847ADAM10ADAM metallopeptidase domain 10155858880958749707Human

Position Markers

Peak: (rs80236739)
Human AssemblyChrPosition (strand)Source
GRCh381558,680,500 - 58,680,501RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407192897GWAS841873_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS841873 (human)7e-25triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407199233GWAS848209_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS848209 (human)3e-11lipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407346499GWAS995475_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS995475 (human)2e-15phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407331725GWAS980701_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS980701 (human)4e-15very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155868050058680501Human
407191369GWAS840345_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS840345 (human)1e-10phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407117896GWAS766872_Htriglycerides in very large HDL measurement QTL GWAS766872 (human)2e-12total cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155868050058680501Human
407165706GWAS814682_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS814682 (human)7e-09blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407098828GWAS747804_Hfree cholesterol to total lipids in small HDL percentage QTL GWAS747804 (human)1e-15free cholesterol to total lipids in small HDL percentage 155868050058680501Human
407345687GWAS994663_Hcholesteryl ester measurement, high density lipoprotein cholesterol measurement QTL GWAS994663 (human)2e-11blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407344726GWAS993702_Hhigh density lipoprotein cholesterol measurement QTL GWAS993702 (human)1e-16high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407343702GWAS992678_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS992678 (human)6e-15lipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407333525GWAS982501_Hvery low density lipoprotein cholesterol measurement QTL GWAS982501 (human)2e-13very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155868050058680501Human
407316307GWAS965283_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS965283 (human)9e-12total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407346131GWAS995107_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS995107 (human)1e-18triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407095382GWAS744358_Hcholesterol to total lipids in very large HDL percentage QTL GWAS744358 (human)2e-14cholesterol to total lipids in very large HDL percentage 155868050058680501Human
407332191GWAS981167_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS981167 (human)1e-13phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407182492GWAS831468_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS831468 (human)6e-09free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407289498GWAS938474_Hphospholipid measurement QTL GWAS938474 (human)3e-08phospholipid measurement155868050058680501Human
407119257GWAS768233_Htriglycerides in IDL measurement QTL GWAS768233 (human)5e-11triglycerides in IDL measurementblood lipoprotein triglyceride level (CMO:0002685)155868050058680501Human
407333082GWAS982058_Hcholesteryl ester measurement, very low density lipoprotein cholesterol measurement QTL GWAS982058 (human)1e-11blood lipid amount (VT:0003949)blood very low density lipoprotein cholesterol level (CMO:0000648)155868050058680501Human
407196698GWAS845674_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS845674 (human)4e-12free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407347558GWAS996534_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS996534 (human)7e-13free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407265888GWAS914864_Hhigh density lipoprotein particle size measurement QTL GWAS914864 (human)3e-14cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407058020GWAS706996_Hapolipoprotein A 1 measurement QTL GWAS706996 (human)1e-12apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)155868050058680501Human
407333870GWAS982846_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS982846 (human)9e-15very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)155868050058680501Human
407165416GWAS814392_Hhigh density lipoprotein cholesterol measurement QTL GWAS814392 (human)7e-12high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407096562GWAS745538_Hcholesteryl esters to total lipids in small HDL percentage QTL GWAS745538 (human)5e-10cholesteryl esters to total lipids in small HDL percentage 155868050058680501Human
407342323GWAS991299_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS991299 (human)3e-18cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407270205GWAS919181_Htotal cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS919181 (human)1e-09total cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human
407320762GWAS969738_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS969738 (human)2e-21free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155868050058680501Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS706996_H GCST010241 Apolipoprotein A1 levels 393,193 European ancestry individuals A 0.950165 1E-12 12 rs80236739 0.0320701 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:32203549
GWAS744358_H GCST90269727 Cholesterol to total lipids in very large HDL percentage (UKB data field 23630) 88,307 European ancestry individuals G 0.049611 2E-14 13.699 rs80236739 0.0797094 cholesterol to total lipids in very large HDL percentage (EFO:0022243)
 PMID:36764567
GWAS745538_H GCST90269743 Cholesteryl esters to total lipids in small HDL percentage (UKB data field 23646) 88,329 European ancestry individuals G 0.04961 5E-10 9.302 rs80236739 0.0668539 cholesteryl esters to total lipids in small HDL percentage (EFO:0022254)
 PMID:36764567
GWAS747804_H GCST90269744 Free cholesterol to total lipids in small HDL percentage (UKB data field 23647) 88,329 European ancestry individuals G 0.04961 1E-15 15 rs80236739 0.0836242 free cholesterol to total lipids in small HDL percentage (EFO:0022285)
 PMID:36764567
GWAS766872_H GCST90269654 Triglycerides in very large HDL (UKB data field 23557) 88,329 European ancestry individuals G 0.04961 2E-12 11.699 rs80236739 0.0752611 triglycerides in very large HDL measurement (EFO:0022324)
 PMID:36764567
GWAS768233_H GCST90269626 Triglycerides in IDL (UKB data field 23529) 88,329 European ancestry individuals G 0.04961 5E-11 10.302 rs80236739 0.070485 triglycerides in IDL measurement (EFO:0022149)
 PMID:36764567
GWAS814392_H GCST90092851 Concentration of large HDL particles 115,082 European ancestry individuals A 0.950557 7E-12 11.155 rs80236739 0.0572445 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS814682_H GCST90092846 Cholesteryl ester levels in large HDL 115,082 European ancestry individuals A 0.950557 7E-9 8.155 rs80236739 0.048916 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS831468_H GCST90092867 Triglycerides to total lipids ratio in large LDL 115,082 European ancestry individuals A 0.950557 6E-9 8.222 rs80236739 0.0539811 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS840345_H GCST90092852 Phospholipid levels in large HDL 115,082 European ancestry individuals A 0.950557 1E-10 10 rs80236739 0.053718 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS841873_H GCST90092854 Triglyceride levels in large HDL 115,082 European ancestry individuals A 0.950557 7E-25 24.155 rs80236739 0.0930218 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS845674_H GCST90092848 Free cholesterol levels in large HDL 115,082 European ancestry individuals A 0.950557 4E-12 11.398 rs80236739 0.0580771 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092849 Free cholesterol to total lipids ratio in large HDL 115,082 European ancestry individuals A 0.950557 4E-12 11.398 rs80236739 0.0615125 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS848209_H GCST90092850 Total lipid levels in large HDL 115,082 European ancestry individuals A 0.950557 3E-11 10.523 rs80236739 0.0554692 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092824 Free cholesterol levels in HDL 115,082 European ancestry individuals A 0.950557 6E-9 8.222 rs80236739 0.0491633 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS914864_H GCST90092828 Average diameter for HDL particles 115,082 European ancestry individuals A 0.950557 3E-14 13.523 rs80236739 0.064222 high density lipoprotein particle size measurement (EFO:0008592)
 PMID:35213538
GWAS919181_H GCST90092844 Cholesterol levels in large HDL 115,082 European ancestry individuals A 0.950557 1E-9 9 rs80236739 0.0511372 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90092897 Free cholesterol to total lipids ratio in medium HDL 115,082 European ancestry individuals A 0.950557 6E-9 8.222 rs80236739 0.0491377 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS938474_H GCST90092937 Phosphatidylcholine levels 115,006 European ancestry individuals A 0.950546 3E-8 7.523 rs80236739 0.0495714 phospholipid measurement (EFO:0004639)
 PMID:35213538
None Available GCST90092947 Cholesteryl esters to total lipids ratio in small HDL 115,082 European ancestry individuals A 0.950557 3E-14 13.523 rs80236739 0.0705814 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS965283_H GCST90093004 Cholesterol levels in very large HDL 115,082 European ancestry individuals A 0.950557 9E-12 11.046 rs80236739 0.0587953 total cholesterol measurement (EFO:0004574)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS969738_H GCST90092949 Free cholesterol to total lipids ratio in small HDL 115,082 European ancestry individuals A 0.950557 2E-21 20.699 rs80236739 0.0857825 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS980701_H GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals A 0.950557 4E-15 14.398 rs80236739 0.073354 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
GWAS981167_H GCST90093032 Free cholesterol levels in very small VLDL 115,082 European ancestry individuals A 0.950557 1E-13 13 rs80236739 0.0692653 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90093028 Cholesterol levels in very small VLDL 115,082 European ancestry individuals A 0.950557 2E-12 11.699 rs80236739 0.065122 total cholesterol measurement (EFO:0004574)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS982058_H GCST90093030 Cholesteryl ester levels in very small VLDL 115,082 European ancestry individuals A 0.950557 1E-11 11 rs80236739 0.0623406 cholesteryl ester measurement (EFO:0010351)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS982501_H GCST90093035 Concentration of very small VLDL particles 115,082 European ancestry individuals A 0.950557 2E-13 12.699 rs80236739 0.0689249 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
GWAS982846_H GCST90093034 Total lipid levels in very small VLDL 115,082 European ancestry individuals A 0.950557 9E-15 14.046 rs80236739 0.0723329 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
 PMID:35213538
GWAS991299_H GCST90093005 Cholesterol to total lipids ratio in very large HDL 115,056 European ancestry individuals A 0.950555 3E-18 17.523 rs80236739 0.0788291 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS992678_H GCST90093010 Total lipid levels in very large HDL 115,082 European ancestry individuals A 0.950557 6E-15 14.222 rs80236739 0.0668138 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
None Available GCST90093013 Phospholipids to total lipids ratio in very large HDL 115,056 European ancestry individuals A 0.950555 1E-13 13 rs80236739 0.0647895 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS993702_H GCST90093011 Concentration of very large HDL particles 115,082 European ancestry individuals A 0.950557 1E-16 16 rs80236739 0.0708837 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS994663_H GCST90093006 Cholesteryl ester levels in very large HDL 115,082 European ancestry individuals A 0.950557 2E-11 10.699 rs80236739 0.0574287 cholesteryl ester measurement (EFO:0010351)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS995107_H GCST90093014 Triglyceride levels in very large HDL 115,082 European ancestry individuals A 0.950557 1E-18 18 rs80236739 0.0816125 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS995475_H GCST90093012 Phospholipid levels in very large HDL 115,082 European ancestry individuals A 0.950557 2E-15 14.699 rs80236739 0.0680893 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS996534_H GCST90093009 Free cholesterol to total lipids ratio in very large HDL 115,056 European ancestry individuals A 0.950555 7E-13 12.155 rs80236739 0.0605179 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90093036 GWAS Catalog

RGD Curation Notes
Note Type Note Reference