GWAS968174_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS968174_H (HbA1c measurement QTL GWAS968174 (human)) Homo sapiens

Symbol: GWAS968174_H
Name: HbA1c measurement QTL GWAS968174 (human)
RGD ID: 407319198
Trait: HbA1c measurement
Measurement Type: blood hemoglobin A1c level   (CMO:0002786)    
LOD Score: Not Available
P Value: 4.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382236,286,753 - 36,286,754RGD_MAPPER_PIPELINEGRCh38
GRCh372236,682,799 - 36,682,800RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS968174_HHumanblood hemoglobin A1c level  IAGPrs138158369405850206Based on the EFO term IDGWAS_CATALOGPMID:33462484

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS968174_HHumanHbA1c measurement  IAGPrs138158369405850206 GWAS_CATALOGPMID:33462484
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
732401MYH9myosin heavy chain 9223628128036387967Human
155775154LOC127896023H3K4me1 hESC enhancer GRCh37_chr22:36682442-36682954223628639636286908Human

Position Markers

Peak: (rs138158369)
Human AssemblyChrPosition (strand)Source
GRCh382236,286,753 - 36,286,754RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581529BP71_HBlood pressure QTL 71 (human)20.001Blood pressurepulse pressure221109496637094966Human
2289428BW313_HBody weight QTL 313 (human)2.090.0015Body weightBMI221134428437344284Human
407319198GWAS968174_HHbA1c measurement QTL GWAS968174 (human)4e-13HbA1c measurementblood hemoglobin A1c level (CMO:0002786)223628675336286754Human
407233370GWAS882346_HHbA1c measurement QTL GWAS882346 (human)8e-12HbA1c measurementblood hemoglobin A1c level (CMO:0002786)223628675336286754Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS882346_H GCST90025974 Hemoglobin A1c levels 437,749 European ancestry individuals ? NR 8E-12 11.097 rs138158369 0.263835 HbA1c measurement (EFO:0004541)
 PMID:34226706
GWAS968174_H GCST90019509 Glycated hemoglobin levels 327,177 European ancestry individuals, 4,847 African ancestry individuals, 6,895 South Asian ancestry individuals C NR 4E-13 12.398 rs138158369 0.3559 HbA1c measurement (EFO:0004541)
 PMID:33462484
Database Acc Id Source(s)
GWAS Catalog GCST90019509 GWAS Catalog

RGD Curation Notes
Note Type Note Reference