GWAS895365_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS895365_H (angina pectoris QTL GWAS895365 (human)) Homo sapiens

Symbol: GWAS895365_H
Name: angina pectoris QTL GWAS895365 (human)
RGD ID: 407246389
Trait: angina pectoris
LOD Score: Not Available
P Value: 5.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810102,876,519 - 102,876,520RGD_MAPPER_PIPELINEGRCh38
GRCh3710104,636,276 - 104,636,277RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7365766BORCS7-ASMTBORCS7-ASMT readthrough (NMD candidate)10102854210102901899Human
1350697AS3MTarsenite methyltransferase10102869470102901899Human

Position Markers

Peak: (rs77335224)
Human AssemblyChrPosition (strand)Source
GRCh3810102,876,519 - 102,876,520RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407179782GWAS828758_Hmean corpuscular volume QTL GWAS828758 (human)2e-12mean corpuscular volumemean corpuscular volume (CMO:0000038)10102876519102876520Human
407246389GWAS895365_Hangina pectoris QTL GWAS895365 (human)5e-15angina pectoris10102876519102876520Human
407234614GWAS883590_Hhip circumference QTL GWAS883590 (human)1e-08hip circumferencehip circumference (CMO:0000014)10102876519102876520Human
2314551GLUCO52_HGlucose level QTL 52 (human)1.4Glucose level1077605006103605006Human
406962293GWAS611269_Hneuroticism measurement QTL GWAS611269 (human)5e-09neuroticism measurement10102876519102876520Human
407077126GWAS726102_Hhippocampal amigdala transition area volume QTL GWAS726102 (human)2e-09hippocampal amigdala transition area volume10102876519102876520Human
407252861GWAS901837_Hangina pectoris QTL GWAS901837 (human)1e-09angina pectoris10102876519102876520Human
407236792GWAS885768_Hbody weight QTL GWAS885768 (human)5e-10body mass (VT:0001259)body weight (CMO:0000012)10102876519102876520Human
407111194GWAS760170_Hbody mass index QTL GWAS760170 (human)1e-11body mass indexbody mass index (BMI) (CMO:0000105)10102876519102876520Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS611269_H GCST006476 Neuroticism 449,484 European ancestry individuals T NR 5E-9 8.302 rs77335224 5.859 neuroticism measurement (EFO:0007660)
 PMID:29942085
GWAS726102_H GCST90267925 Hippocampal right HATA volume 38,977 European ancestry, East Asian ancestry individuals T 0.25234 2E-9 8.699 rs77335224 0.0676896 hippocampal amigdala transition area volume (EFO:0009401)
 PMID:37337106
GWAS760170_H GCST009001 Body mass index 374,756 European ancestry male individuals T 0.0901 1E-11 11 rs77335224 0.0225 body mass index (EFO:0004340)
 PMID:30239722
GWAS828758_H GCST90002397 Mean spheric corpuscular volume 408,112 British individuals T 0.086405 2E-12 11.699 rs77335224 0.027921274 mean corpuscular volume (EFO:0004526)
 PMID:32888494
GWAS883590_H GCST90278633 Hip circumference 92,615 Taiwanese ancestry individuals ? NR 1E-8 8 rs77335224 N/A hip circumference (EFO:0005093)
 PMID:38116116
GWAS885768_H GCST90278650 Weight 92,615 Taiwanese ancestry individuals ? NR 5E-10 9.302 rs77335224 N/A body weight (EFO:0004338)
 PMID:38116116
GWAS895365_H GCST90018793 Angina pectoris 30,025 European ancestry cases, 440,906 European ancestry controls, 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls T NR 5E-15 14.302 rs77335224 0.0896 angina pectoris (EFO:0003913)
 PMID:34594039
GWAS901837_H GCST90018573 Angina pectoris 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls T 0.245126703 1E-9 9 rs77335224 0.09537856 angina pectoris (EFO:0003913)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90018793 GWAS Catalog

RGD Curation Notes
Note Type Note Reference