GWAS866920_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS866920_H (blood protein measurement QTL GWAS866920 (human)) Homo sapiens

Symbol: GWAS866920_H
Name: blood protein measurement QTL GWAS866920 (human)
RGD ID: 407217944
Trait: blood protein measurement
Measurement Type: blood protein measurement   (CMO:0000028)    
LOD Score: Not Available
P Value: 4.0E-36
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381550,492,819 - 50,492,820RGD_MAPPER_PIPELINEGRCh38
GRCh371550,785,016 - 50,785,017RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS866920_HHumanblood protein measurement  IAGPrs148783236405850206Based on the EFO term IDGWAS_CATALOGPMID:38412862

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS866920_HHumanblood protein measurement  IAGPrs148783236405850206 GWAS_CATALOGPMID:38412862
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1312730USP8ubiquitin specific peptidase 8155042440550514421Human

Position Markers

Peak: (rs148783236)
Human AssemblyChrPosition (strand)Source
GRCh381550,492,819 - 50,492,820RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406950177GWAS599153_Hprotein measurement QTL GWAS599153 (human)4e-14protein measurement155049281950492820Human
407000867GWAS649843_Hankylosing spondylitis QTL GWAS649843 (human)1e-13ankylosing spondylitis155049281950492820Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407219170GWAS868146_Hblood protein measurement QTL GWAS868146 (human)2e-48blood protein measurementblood protein measurement (CMO:0000028)155049281950492820Human
407081384GWAS730360_Hblood protein measurement QTL GWAS730360 (human)1e-194blood protein measurementblood protein measurement (CMO:0000028)155049281950492820Human
407203790GWAS852766_Hblood protein measurement QTL GWAS852766 (human)7e-266blood protein measurementblood protein measurement (CMO:0000028)155049281950492820Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
406948396GWAS597372_Hubiquitin carboxyl-terminal hydrolase 25 measurement QTL GWAS597372 (human)2e-17ubiquitin carboxyl-terminal hydrolase 25 measurement155049281950492820Human
406955887GWAS604863_Hprotein measurement QTL GWAS604863 (human)8e-35protein measurement155049281950492820Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
406947889GWAS596865_HMHC class I polypeptide-related sequence A measurement QTL GWAS596865 (human)2e-19MHC class I polypeptide-related sequence A measurement155049281950492820Human
406947890GWAS596866_HMHC class I polypeptide-related sequence B measurement QTL GWAS596866 (human)2e-79MHC class I polypeptide-related sequence B measurement155049281950492820Human
406961685GWAS610661_Hcomplement C4 measurement QTL GWAS610661 (human)5e-40complement C4 measurement155049281950492820Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407203792GWAS852768_Hblood protein measurement QTL GWAS852768 (human)2e-250blood protein measurementblood protein measurement (CMO:0000028)155049281950492820Human
406959668GWAS608644_Hprotein measurement QTL GWAS608644 (human)1e-16protein measurement155049281950492820Human
407078683GWAS727659_Hblood protein measurement QTL GWAS727659 (human)3e-30blood protein measurementblood protein measurement (CMO:0000028)155049281950492820Human
407187929GWAS836905_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS836905 (human)3e-14aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)155049281950492820Human
407189080GWAS838056_Htotal cholesterol measurement QTL GWAS838056 (human)1e-11total cholesterol measurementblood total cholesterol level (CMO:0000051)155049281950492820Human
407217944GWAS866920_Hblood protein measurement QTL GWAS866920 (human)4e-36blood protein measurementblood protein measurement (CMO:0000028)155049281950492820Human
406951198GWAS600174_Hprotein measurement QTL GWAS600174 (human)4e-20protein measurement155049281950492820Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS596865_H GCST90248468 MHC class I polypeptide-related sequence A levels 10,708 European ancestry individuals A 0.87 2E-19 18.699 rs148783236 0.203 MHC class I polypeptide-related sequence A measurement (EFO:0008233)
 PMID:34648354
GWAS596866_H GCST90248469 MHC class I polypeptide-related sequence B levels 10,708 European ancestry individuals A 0.87 2E-79 78.699 rs148783236 0.423 MHC class I polypeptide-related sequence B measurement (EFO:0008234)
 PMID:34648354
GWAS597372_H GCST90250076 Ubiquitin carboxyl-terminal hydrolase 25 levels 10,708 European ancestry individuals A 0.87 2E-17 16.699 rs148783236 0.187 ubiquitin carboxyl-terminal hydrolase 25 measurement (EFO:0021881)
 PMID:34648354
GWAS599153_H GCST90248169 Killer cell immunoglobulin-like receptor 2DL3 levels 10,708 European ancestry individuals A 0.87 4E-14 13.398 rs148783236 0.173 protein measurement (EFO:0004747)
 PMID:34648354
GWAS600174_H GCST90247643 Ferritin, mitochondrial levels 10,708 European ancestry individuals A 0.87 4E-20 19.398 rs148783236 0.209 protein measurement (EFO:0004747)
 PMID:34648354
GWAS604863_H GCST90249784 T-cell surface glycoprotein CD8 alpha chain levels 10,708 European ancestry individuals A 0.87 8E-35 34.097 rs148783236 0.266 protein measurement (EFO:0004747)
 PMID:34648354
GWAS608644_H GCST90250016 Thioredoxin domain-containing protein 15 levels 10,708 European ancestry individuals A 0.87 1E-16 16 rs148783236 0.187 protein measurement (EFO:0004747)
 PMID:34648354
GWAS610661_H GCST90246780 Complement C4 levels 10,708 European ancestry individuals A 0.87 5E-40 39.302 rs148783236 0.301 complement C4 measurement (EFO:0004984)
 PMID:34648354
GWAS649843_H GCST007844 Ankylosing spondylitis 921 Turkish ancestry cases, 907 Turkish ancestry controls, 422 Iranian ancestry cases, 754 Iranian ancestry controls A NR 1E-13 13 rs148783236 1.724138 ankylosing spondylitis (EFO:0003898)
 PMID:30946743
GWAS727659_H GCST90315016 GZMH/KLRD1 protein level ratio 43,509 European ancestry individuals ? NR 3E-30 29.523 rs148783236 0.120393 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS730360_H GCST90315011 GZMA/KIR2DL3 protein level ratio 43,509 European ancestry individuals ? NR 1E-194 194 rs148783236 0.315125 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS836905_H GCST90019498 Aspartate aminotransferase to alanine aminotransferase ratio 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals G NR 3E-14 13.523 rs148783236 0.0278 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:33462484
GWAS838056_H GCST90019501 Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals G NR 1E-11 11 rs148783236 0.0248 total cholesterol measurement (EFO:0004574)
 PMID:33462484
GWAS852766_H GCST90313997 CDSN/LY6D protein level ratio 43,509 European ancestry individuals ? NR 7E-266 265.155 rs148783236 0.36591 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS852768_H GCST90313998 CDSN/NECTIN4 protein level ratio 43,509 European ancestry individuals ? NR 2E-250 249.699 rs148783236 0.356601 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS866920_H GCST90315117 ICAM2/IL7R protein level ratio 43,509 European ancestry individuals ? NR 4E-36 35.398 rs148783236 0.132369 blood protein measurement (EFO:0007937)
 PMID:38412862
GWAS868146_H GCST90315306 LCN2/PGLYRP1 protein level ratio 43,509 European ancestry individuals ? NR 2E-48 47.699 rs148783236 0.155795 blood protein measurement (EFO:0007937)
 PMID:38412862
Database Acc Id Source(s)
GWAS Catalog GCST90315117 GWAS Catalog

RGD Curation Notes
Note Type Note Reference