GWAS859669_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS859669_H (cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS859669 (human)) Homo sapiens

Symbol: GWAS859669_H
Name: cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS859669 (human)
RGD ID: 407210693
Trait: cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 5.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38629,936,214 - 29,936,215RGD_MAPPER_PIPELINEGRCh38
GRCh37629,903,991 - 29,903,992RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS859669_HHumanblood low density lipoprotein cholesterol level  IAGPrs9259970405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS859669_HHumancholesterol:total lipids ratio  IAGPrs9259970405850206 GWAS_CATALOGPMID:35213538
GWAS859669_HHumanlow density lipoprotein cholesterol measurement  IAGPrs9259970405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
151673698LOC124901298uncharacterized LOC12490129862992819829945593Human

Position Markers

Peak: (rs9259970)
Human AssemblyChrPosition (strand)Source
GRCh38629,936,214 - 29,936,215RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407210693GWAS859669_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS859669 (human)5e-08cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)62993621429936215Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
407081928GWAS730904_Htriglycerides to total lipids in small VLDL percentage QTL GWAS730904 (human)3e-11triglycerides to total lipids in small VLDL percentage 62993621429936215Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
407204938GWAS853914_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS853914 (human)4e-15very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)62993621429936215Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
407159600GWAS808576_Hcholesterol:total lipids ratio, intermediate density lipoprotein measurement QTL GWAS808576 (human)6e-10cholesterol:total lipids ratio, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)62993621429936215Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human
407079549GWAS728525_Hcholesterol to total lipids in small VLDL percentage QTL GWAS728525 (human)5e-12cholesterol to total lipids in small VLDL percentage 62993621429936215Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS728525_H GCST90269697 Cholesterol to total lipids in small VLDL percentage (UKB data field 23600) 88,329 European ancestry individuals A 0.27728 5E-12 11.302 rs9259970 0.0396882 cholesterol to total lipids in small VLDL percentage (EFO:0022242)
 PMID:36764567
GWAS730904_H GCST90269700 Triglycerides to total lipids in small VLDL percentage (UKB data field 23603) 88,329 European ancestry individuals A 0.27728 3E-11 10.523 rs9259970 0.0378288 triglycerides to total lipids in small VLDL percentage (EFO:0022338)
 PMID:36764567
GWAS808576_H GCST90092832 Cholesterol to total lipids ratio in IDL 115,082 European ancestry individuals G 0.717498 6E-10 9.222 rs9259970 0.0286546 cholesterol:total lipids ratio (EFO:0020943)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS853914_H GCST90093033 Free cholesterol to total lipids ratio in very small VLDL 115,082 European ancestry individuals G 0.717498 4E-15 14.398 rs9259970 0.0371322 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS859669_H GCST90092905 Cholesterol to total lipids ratio in medium LDL 115,082 European ancestry individuals G 0.717498 5E-8 7.302 rs9259970 0.0259759 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90092905 GWAS Catalog

RGD Curation Notes
Note Type Note Reference