GWAS858773_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS858773_H (triglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS858773 (human)) Homo sapiens

Symbol: GWAS858773_H
Name: triglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS858773 (human)
RGD ID: 407209797
Trait: triglyceride measurement, low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
blood triglyceride level   (CMO:0000118)    
LOD Score: Not Available
P Value: 1E-390
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,430,391 - 58,430,393RGD_MAPPER_PIPELINEGRCh38
GRCh371558,722,590 - 58,722,592RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS858773_HHumanblood low density lipoprotein cholesterol level  IAGPrs35980001405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538
GWAS858773_HHumanblood triglyceride level  IAGPrs35980001405850206Based on the EFO term IDGWAS_CATALOGPMID:35213538

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS858773_HHumanlow density lipoprotein cholesterol measurement  IAGPrs35980001405850206 GWAS_CATALOGPMID:35213538
GWAS858773_HHumantriglyceride measurement  IAGPrs35980001405850206 GWAS_CATALOGPMID:35213538
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs35980001)
Human AssemblyChrPosition (strand)Source
GRCh381558,430,391 - 58,430,393RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407209797GWAS858773_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS858773 (human)1e-390triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407217346GWAS866322_Hvitamin D measurement QTL GWAS866322 (human)6e-14vitamin D measurement155843039158430393Human
407242254GWAS891230_H1-oleoyl-GPE (18:1) measurement QTL GWAS891230 (human)4e-241-oleoyl-GPE (18:1) measurement155843039158430393Human
407252751GWAS901727_Hlow density lipoprotein cholesterol measurement QTL GWAS901727 (human)2e-18low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407157070GWAS806046_Hhigh density lipoprotein particle size measurement QTL GWAS806046 (human)1e-427high density lipoprotein particle size measurementblood high density lipoprotein particle diameter (CMO:0002692)155843039158430393Human
407206543GWAS855519_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS855519 (human)5e-80very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human
407158665GWAS807641_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS807641 (human)2e-342free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407208264GWAS857240_Hlow density lipoprotein cholesterol measurement QTL GWAS857240 (human)1e-43low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407158932GWAS807908_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS807908 (human)1e-364low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407160085GWAS809061_Hhigh density lipoprotein cholesterol measurement QTL GWAS809061 (human)1e-340high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407249362GWAS898338_Htriglyceride measurement QTL GWAS898338 (human)1e-37triglyceride measurementblood triglyceride level (CMO:0000118)155843039158430393Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407157713GWAS806689_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS806689 (human)9e-640triglyceride measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)155843039158430393Human
407201695GWAS850671_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS850671 (human)6e-612cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407154655GWAS803631_Hhigh density lipoprotein cholesterol measurement QTL GWAS803631 (human)1e-305high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407159577GWAS808553_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS808553 (human)5e-326lipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407222872GWAS871848_HC36:4 phosphatidylethanolamine measurement QTL GWAS871848 (human)3e-11C36:4 phosphatidylethanolamine measurement155843039158430393Human
407158683GWAS807659_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS807659 (human)4e-508triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407201188GWAS850164_Hlipid measurement, high density lipoprotein cholesterol measurement QTL GWAS850164 (human)2e-381very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human
407202983GWAS851959_Hvery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS851959 (human)2e-09very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human
407197542GWAS846518_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS846518 (human)2e-552cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407241445GWAS890421_H1-linoleoyl-GPE (18:2) measurement QTL GWAS890421 (human)2e-131-linoleoyl-GPE (18:2) measurement155843039158430393Human
407199841GWAS848817_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS848817 (human)7e-398phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407204384GWAS853360_Hfree cholesterol measurement, very low density lipoprotein cholesterol measurement QTL GWAS853360 (human)2e-370free cholesterol measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human
407202723GWAS851699_Hhigh density lipoprotein cholesterol measurement QTL GWAS851699 (human)6e-450high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
406903719GWAS552695_H1-arachidonoyl-GPE (20:4n6) measurement QTL GWAS552695 (human)2e-161-arachidonoyl-GPE (20:4n6) measurement155843039158430393Human
407218860GWAS867836_Hvitamin D measurement QTL GWAS867836 (human)5e-25vitamin D measurement155843039158430393Human
406893739GWAS542715_Hglycerophosphoethanolamine measurement QTL GWAS542715 (human)2e-19glycerophosphoethanolamine measurement155843039158430393Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407161258GWAS810234_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS810234 (human)1e-84very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human
407218859GWAS867835_Hvitamin D measurement QTL GWAS867835 (human)1e-09vitamin D measurement155843039158430393Human
407217770GWAS866746_H1-myristoyl-2-palmitoyl-GPC (14:0/16:0) measurement QTL GWAS866746 (human)3e-091-myristoyl-2-palmitoyl-GPC (14:0/16:0) measurement155843039158430393Human
407159601GWAS808577_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS808577 (human)3e-368triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407210160GWAS859136_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS859136 (human)3e-409triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407204400GWAS853376_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS853376 (human)7e-461very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human
406896246GWAS545222_H1-palmitoyl-2-stearoyl-GPC (16:0/18:0) measurement QTL GWAS545222 (human)7e-171-palmitoyl-2-stearoyl-GPC (16:0/18:0) measurement155843039158430393Human
407202931GWAS851907_Hphospholipids:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS851907 (human)2e-385phospholipids:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407158204GWAS807180_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS807180 (human)5e-353triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843039158430393Human
407203260GWAS852236_Hvery low density lipoprotein cholesterol measurement, lipid measurement QTL GWAS852236 (human)1e-435very low density lipoprotein cholesterol measurement, lipid measurementblood lipid measurement (CMO:0000050)155843039158430393Human
407202238GWAS851214_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS851214 (human)7e-379free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843039158430393Human
407206843GWAS855819_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS855819 (human)1e-430triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155843039158430393Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS542715_H GCST90245224 Glycerophosphoethanolamine levels 14,296 European ancestry individuals ? 0.7923 2E-19 18.699 rs35980001 0.11082318 glycerophosphoethanolamine measurement (EFO:0800253)
PMID:36357675
GWAS545222_H GCST90244950 1-palmitoyl-2-stearoyl-gpc (16:0/18:0) levels 14,296 European ancestry individuals ? 0.7932 7E-17 16.155 rs35980001 0.10498361 1-palmitoyl-2-stearoyl-GPC (16:0/18:0) measurement (EFO:0800396)
PMID:36357675
GWAS552695_H GCST90102672 1-arachidonoyl-GPE (20:4n6) levels 8,809 European ancestry individuals GC NR 2E-16 15.699 rs35980001 0.151 1-arachidonoyl-GPE (20:4n6) measurement (EFO:0800248)
PMID:35050183
GWAS803631_H GCST90244005 HDL cholesterol levels 288,127 East Asian ancestry individuals GC 0.3691 1E-305 305 rs35980001 0.1597 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:36333282
GWAS806046_H GCST90092828 Average diameter for HDL particles 115,082 European ancestry individuals G 0.787529 1E-427 427 rs35980001 0.198526 high density lipoprotein particle size measurement (EFO:0008592)
PMID:35213538
GWAS806689_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals G 0.787529 9E-640 639.046 rs35980001 0.267634 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
PMID:35213538
GWAS807180_H GCST90092867 Triglycerides to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.787529 5E-353 352.302 rs35980001 0.197896 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
GWAS807641_H GCST90092848 Free cholesterol levels in large HDL 115,082 European ancestry individuals G 0.787529 2E-342 341.699 rs35980001 0.17579 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS807659_H GCST90092866 Triglyceride levels in large LDL 115,082 European ancestry individuals G 0.787529 4E-508 507.398 rs35980001 0.239458 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
GWAS807908_H GCST90092865 Phospholipids to total lipids ratio in large LDL 115,082 European ancestry individuals G 0.787529 1E-364 364 rs35980001 0.206879 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
PMID:35213538
GWAS808553_H GCST90092850 Total lipid levels in large HDL 115,082 European ancestry individuals G 0.787529 5E-326 325.302 rs35980001 0.171679 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS808577_H GCST90092829 Triglyceride levels in HDL 115,082 European ancestry individuals G 0.787529 3E-368 367.523 rs35980001 0.203532 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS809061_H GCST90092851 Concentration of large HDL particles 115,082 European ancestry individuals G 0.787529 1E-340 340 rs35980001 0.175249 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS810234_H GCST90092873 Free cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.787553 1E-84 84 rs35980001 0.09808 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
PMID:35213538
GWAS846518_H GCST90092947 Cholesteryl esters to total lipids ratio in small HDL 115,082 European ancestry individuals G 0.787529 2E-552 551.699 rs35980001 0.249121 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS848817_H GCST90093012 Phospholipid levels in very large HDL 115,082 European ancestry individuals G 0.787529 7E-398 397.155 rs35980001 0.194454 phospholipid measurement (EFO:0004639)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS850164_H GCST90093010 Total lipid levels in very large HDL 115,082 European ancestry individuals G 0.787529 2E-381 380.699 rs35980001 0.190407 lipid measurement (EFO:0004529)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS850671_H GCST90093005 Cholesterol to total lipids ratio in very large HDL 115,056 European ancestry individuals G 0.787507 6E-612 611.222 rs35980001 0.255152 cholesterol:total lipids ratio (EFO:0020943)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS851214_H GCST90093009 Free cholesterol to total lipids ratio in very large HDL 115,056 European ancestry individuals G 0.787507 7E-379 378.155 rs35980001 0.186841 free cholesterol:total lipids ratio (EFO:0020945)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS851699_H GCST90093011 Concentration of very large HDL particles 115,082 European ancestry individuals G 0.787529 6E-450 449.222 rs35980001 0.207091 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS851907_H GCST90093013 Phospholipids to total lipids ratio in very large HDL 115,056 European ancestry individuals G 0.787507 2E-385 384.699 rs35980001 0.195483 phospholipids:total lipids ratio (EFO:0020946)
high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:35213538
GWAS851959_H GCST90092971 Cholesteryl esters to total lipids ratio in small VLDL 115,082 European ancestry individuals G 0.787529 2E-9 8.699 rs35980001 0.0299277 very low density lipoprotein cholesterol measurement (EFO:0008317)
cholesteryl esters:total lipids ratio (EFO:0020944)
PMID:35213538
GWAS852236_H GCST90093034 Total lipid levels in very small VLDL 115,082 European ancestry individuals G 0.787529 1E-435 435 rs35980001 0.221563 very low density lipoprotein cholesterol measurement (EFO:0008317)
lipid measurement (EFO:0004529)
PMID:35213538
None Available GCST90093035 Concentration of very small VLDL particles 115,082 European ancestry individuals G 0.787529 2E-381 380.699 rs35980001 0.208253 very low density lipoprotein cholesterol measurement (EFO:0008317)
PMID:35213538
GWAS853360_H GCST90093032 Free cholesterol levels in very small VLDL 115,082 European ancestry individuals G 0.787529 2E-370 369.699 rs35980001 0.20437 free cholesterol measurement (EFO:0008591)
very low density lipoprotein cholesterol measurement (EFO:0008317)
PMID:35213538
GWAS853376_H GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals G 0.787529 7E-461 460.155 rs35980001 0.228446 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
PMID:35213538
GWAS855519_H GCST90093025 Phospholipids to total lipids ratio in very large VLDL 114,160 European ancestry individuals G 0.78792 5E-80 79.302 rs35980001 0.0963925 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
PMID:35213538
GWAS855819_H GCST90093038 Triglyceride levels in very small VLDL 115,082 European ancestry individuals G 0.787529 1E-430 430 rs35980001 0.219129 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
PMID:35213538
GWAS857240_H GCST90002412 Low density lipoprotein cholesterol levels 431,167 European ancestry individuals G 0.786565 1E-43 43 rs35980001 0.0327125 low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:32493714
GWAS858773_H GCST90092890 Triglyceride levels in LDL 115,082 European ancestry individuals G 0.787529 1E-390 390 rs35980001 0.209814 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
GWAS859136_H GCST90092915 Triglycerides to total lipids ratio in medium LDL 115,082 European ancestry individuals G 0.787529 3E-409 408.523 rs35980001 0.21486 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:35213538
GWAS866322_H GCST90000620 Serum 25-Hydroxyvitamin D levels 162,591 European ancestry individuals GC 0.21 6E-14 13.222 rs35980001 0.0316 vitamin D measurement (EFO:0004631)
PMID:32242144
GWAS866746_H GCST90244922 1-myristoyl-2-palmitoyl-gpc (14:0/16:0) levels 14,296 European ancestry individuals ? 0.7923 3E-9 8.523 rs35980001 0.073464535 1-myristoyl-2-palmitoyl-GPC (14:0/16:0) measurement (EFO:0800191)
PMID:36357675
GWAS867835_H GCST90000621 Serum 25-Hydroxyvitamin D level variance 318,851 European ancestry individuals GC 0.21 1.0E-9 9 rs35980001 0.019 vitamin D measurement (EFO:0004631)
PMID:32242144
GWAS867836_H GCST90000619 Serum 25-Hydroxyvitamin D levels 177,082 European ancestry individuals GC 0.21 5E-25 24.302 rs35980001 0.0421 vitamin D measurement (EFO:0004631)
PMID:32242144
GWAS871848_H GCST90257357 C36:4 Phosphatidylethanolamine levels in chronic kidney disease 822 European ancestry individuals GC 0.22 3E-11 10.523 rs35980001 0.23 C36:4 phosphatidylethanolamine measurement (EFO:0801140)
PMID:35120996
GWAS890421_H GCST90299688 Metabolite levels (1-linoleoylglycerophosphoethanolamine; 1-linoleoyl-GPE (18:2); C18:2 LPE; C18_2_LPE) 11,268 European, Hispanic or African American individuals GC 0.2911 2E-13 12.699 rs35980001 0.112 1-linoleoyl-GPE (18:2) measurement (EFO:0800247)
PMID:37253714
GWAS891230_H GCST90299736 Metabolite levels (1-oleoylglycerophosphoethanolamine; 1-oleoyl-GPE (18:1); C18:1 LPE; C18_1_LPE) 11,265 European, Hispanic or African American individuals GC 0.2911 4E-24 23.398 rs35980001 0.155 1-oleoyl-GPE (18:1) measurement (EFO:0800246)
PMID:37253714
GWAS898338_H GCST90239663 Triglyceride levels 146,492 East Asian ancestry individuals GC 0.360361 1E-37 37 rs35980001 0.0762318 triglyceride measurement (EFO:0004530)
PMID:34887591
GWAS901727_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 2E-18 17.699 rs35980001 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
PMID:34887591
Database Acc Id Source(s)
GWAS Catalog GCST90092890 GWAS Catalog

RGD Curation Notes
Note Type Note Reference