GWAS810039_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS810039_H (hypertension QTL GWAS810039 (human)) Homo sapiens

Symbol: GWAS810039_H
Name: hypertension QTL GWAS810039 (human)
RGD ID: 407161063
Trait: hypertension
LOD Score: Not Available
P Value: 7.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810102,856,906 - 102,856,907RGD_MAPPER_PIPELINEGRCh38
GRCh3710104,616,663 - 104,616,664RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Hypertension  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7365766BORCS7-ASMTBORCS7-ASMT readthrough (NMD candidate)10102854210102901899Human
1323417BORCS7BLOC-1 related complex subunit 710102854259102864961Human

Position Markers

Peak: (rs4409766)
Human AssemblyChrPosition (strand)Source
GRCh3810102,856,906 - 102,856,907RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407115173GWAS764149_Hpulse pressure measurement QTL GWAS764149 (human)2e-11pulse pressure measurementpulse pressure (CMO:0000292)10102856906102856907Human
407146278GWAS795254_Hbody mass index QTL GWAS795254 (human)5e-11body mass indexbody mass index (BMI) (CMO:0000105)10102856906102856907Human
407161063GWAS810039_Hhypertension QTL GWAS810039 (human)7e-13hypertension10102856906102856907Human
407112289GWAS761265_Hhypertension QTL GWAS761265 (human)4e-10hypertension10102856906102856907Human
407179811GWAS828787_Hwellbeing measurement QTL GWAS828787 (human)2e-08wellbeing measurement10102856906102856907Human
407145836GWAS794812_Hbody mass index QTL GWAS794812 (human)6e-17systolic blood pressuresystolic blood pressure (CMO:0000004)10102856906102856907Human
407166063GWAS815039_Hdiastolic blood pressure QTL GWAS815039 (human)8e-09diastolic blood pressurediastolic blood pressure (CMO:0000005)10102856906102856907Human
407161066GWAS810042_Hdiastolic blood pressure QTL GWAS810042 (human)6e-13diastolic blood pressurediastolic blood pressure (CMO:0000005)10102856906102856907Human
407246632GWAS895608_Hangina pectoris QTL GWAS895608 (human)3e-10angina pectoris10102856906102856907Human
2314551GLUCO52_HGlucose level QTL 52 (human)1.4Glucose level1077605006103605006Human
407166064GWAS815040_Hmean arterial pressure QTL GWAS815040 (human)1e-11mean arterial pressuremean arterial blood pressure (CMO:0000009)10102856906102856907Human
407212944GWAS861920_Hbody mass index QTL GWAS861920 (human)2e-12body mass indexbody mass index (BMI) (CMO:0000105)10102856906102856907Human
407208632GWAS857608_Hsystolic blood pressure QTL GWAS857608 (human)0.000009systolic blood pressuresystolic blood pressure (CMO:0000004)10102856906102856907Human
407112027GWAS761003_Hsystolic blood pressure QTL GWAS761003 (human)3e-12systolic blood pressuresystolic blood pressure (CMO:0000004)10102856906102856907Human
407111195GWAS760171_Hmean arterial pressure QTL GWAS760171 (human)3e-08mean arterial pressuremean arterial blood pressure (CMO:0000009)10102856906102856907Human
407245305GWAS894281_Hbody mass index QTL GWAS894281 (human)6e-12body mass indexbody mass index (BMI) (CMO:0000105)10102856906102856907Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS760171_H GCST007706 Mean arterial pressure 130,777 Japanese ancestry individuals T 0.7171 3E-8 7.523 rs4409766 0.325 mean arterial pressure (EFO:0006340)
 PMID:30487518
GWAS761003_H GCST007703 Systolic blood pressure 130,777 Japanese ancestry individuals T 0.72 3E-12 11.523 rs4409766 0.5793 systolic blood pressure (EFO:0006335)
 PMID:30487518
GWAS761265_H GCST007707 Hypertension 22,566 Japanese ancestry cases, 28,226 Japanese ancestry controls T 0.7171 4E-10 9.398 rs4409766 0.0934 hypertension (EFO:0000537)
 PMID:30487518
GWAS764149_H GCST007705 Pulse pressure 130,777 Japanese ancestry individuals T 0.7171 2E-11 10.699 rs4409766 0.3848 pulse pressure measurement (EFO:0005763)
 PMID:30487518
GWAS794812_H GCST004904 Body mass index up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men C 0.09 6E-17 16.222 rs4409766 0.026 body mass index (EFO:0004340)
 PMID:28892062
GWAS795254_H GCST004904 Body mass index up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men C 0.282 5E-11 10.302 rs4409766 0.025 body mass index (EFO:0004340)
 PMID:28892062
None Available GCST002630 Systolic blood pressure 11,816 Han Chinese ancestry individuals T 0.71 6E-17 16.222 rs4409766 1.24 systolic blood pressure (EFO:0006335)
 PMID:25249183
GWAS810039_H GCST002627 Hypertension 5,065 Han Chinese ancestry cases, 4,404 Han Chinese ancestry controls T 0.71 7E-13 12.155 rs4409766 N/A hypertension (EFO:0000537)
 PMID:25249183
GWAS810042_H GCST002631 Diastolic blood pressure 11,816 Han Chinese ancestry individuals T 0.71 6E-13 12.222 rs4409766 0.59 diastolic blood pressure (EFO:0006336)
 PMID:25249183
GWAS815039_H GCST004258 Diastolic blood pressure (long-term average) 18,422 East Asian ancestry individuals T 0.72 8E-9 8.097 rs4409766 0.4 diastolic blood pressure (EFO:0006336)
 PMID:28348047
GWAS815040_H GCST004259 Mean arterial pressure (long-term average) 18,422 East Asian ancestry individuals T 0.72 1E-11 11 rs4409766 0.54 mean arterial pressure (EFO:0006340)
 PMID:28348047
GWAS828787_H GCST007341 Well-being spectrum (multivariate analysis) 2,083,151 European ancestry individuals C 0.0897670258775019 2E-8 7.699 rs4409766 0.009066736 wellbeing measurement (EFO:0007869)
 PMID:30643256
GWAS857608_H GCST008044 Systolic blood pressure 11,380 African American individuals, 21,549 Hispanic/Latino individuals, 1,086 Asian ancestry individuals, 636 Native American ancestry individuals, 782 individuals ? NR 0.000009 5.046 rs4409766 0.8108596 systolic blood pressure (EFO:0006335)
 PMID:31217584
GWAS861920_H GCST006368 Body mass index 315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals T NR 2E-12 11.699 rs4409766 0.029 body mass index (EFO:0004340)
 PMID:30108127
GWAS894281_H GCST90018727 Body mass index 163,835 East Asian ancestry individuals C 0.28207 6E-12 11.222 rs4409766 0.0242431 body mass index (EFO:0004340)
 PMID:34594039
GWAS895608_H GCST90018932 Unstable angina pectoris 9,481 European ancestry cases, 446,987 European ancestry controls, 5,891 East Asian ancestry cases, 146,214 East Asian ancestry controls C NR 3E-10 9.523 rs4409766 0.1084 angina pectoris (EFO:0003913)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST002627 GWAS Catalog

RGD Curation Notes
Note Type Note Reference