GWAS781886_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS781886_H (body fat percentage QTL GWAS781886 (human)) Homo sapiens

Symbol: GWAS781886_H
Name: body fat percentage QTL GWAS781886 (human)
RGD ID: 407132910
Trait: body fat percentage
Measurement Type: body fat percentage   (CMO:0000302)    
LOD Score: Not Available
P Value: 8.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38629,942,701 - 29,942,702RGD_MAPPER_PIPELINEGRCh38
GRCh37629,910,478 - 29,910,479RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS781886_HHumanbody fat percentage  IAGPrs9260127405850206Based on the EFO term IDGWAS_CATALOGPMID:33980691

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS781886_HHumanbody fat percentage  IAGPrs9260127405850206 GWAS_CATALOGPMID:33980691
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1349444HLA-Amajor histocompatibility complex, class I, A62994253229945870Human
151673698LOC124901298uncharacterized LOC12490129862992819829945593Human

Position Markers

Peak: (rs9260127)
Human AssemblyChrPosition (strand)Source
GRCh38629,942,701 - 29,942,702RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
407134215GWAS783191_Herythrocyte count QTL GWAS783191 (human)6e-12erythrocyte countred blood cell count (CMO:0000025)62994270129942702Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
407132429GWAS781405_Haspartate aminotransferase measurement QTL GWAS781405 (human)4e-17aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)62994270129942702Human
407132910GWAS781886_Hbody fat percentage QTL GWAS781886 (human)8e-12body fat percentagebody fat percentage (CMO:0000302)62994270129942702Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
407131369GWAS780345_Htriglyceride measurement QTL GWAS780345 (human)7e-14triglyceride measurementblood triglyceride level (CMO:0000118)62994270129942702Human
407131371GWAS780347_Haspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement QTL GWAS780347 (human)3e-20aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurementblood high density lipoprotein cholesterol level (CMO:0000052)62994270129942702Human
407132907GWAS781883_Hhigh density lipoprotein cholesterol measurement QTL GWAS781883 (human)4e-13high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)62994270129942702Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS780345_H GCST90020235 Triglycerides 429,011 European ancestry individuals G 0.45 7E-14 13.155 rs9260127 0.015 triglyceride measurement (EFO:0004530)
 PMID:33980691
GWAS780347_H GCST90038594 Metabolic biomarkers (multivariate analysis) 389,354 European ancestry individuals G 0.45 3E-20 19.523 rs9260127 N/A aspartate aminotransferase measurement (EFO:0004736)
serum alanine aminotransferase measurement (EFO:0004735)
low density lipoprotein triglyceride measurement (EFO:0009946)
body fat percentage (EFO:0007800)
More... 		PMID:33980691
GWAS781405_H GCST90020237 Aspartate aminotransferase levels 424,778 European ancestry individuals G 0.45 4E-17 16.398 rs9260127 0.016 aspartate aminotransferase measurement (EFO:0004736)
 PMID:33980691
GWAS781883_H GCST90020233 High density lipoprotein cholesterol levels 392,965 European ancestry individuals G 0.45 4E-13 12.398 rs9260127 0.013 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:33980691
GWAS781886_H GCST90020232 Body fat percentage 442,278 European ancestry individuals G 0.45 8E-12 11.097 rs9260127 0.01 body fat percentage (EFO:0007800)
 PMID:33980691
GWAS783191_H GCST90002403 Red blood cell count 408,112 British individuals C 0.554534 6E-12 11.222 rs9260127 0.01662031 erythrocyte count (EFO:0004305)
 PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST90020232 GWAS Catalog

RGD Curation Notes
Note Type Note Reference