GWAS746734_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS746734_H (reticulocyte count QTL GWAS746734 (human)) Homo sapiens

Symbol: GWAS746734_H
Name: reticulocyte count QTL GWAS746734 (human)
RGD ID: 407097758
Trait: reticulocyte count
Measurement Type: total reticulocyte count   (CMO:0003020)    
LOD Score: Not Available
P Value: 4.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810102,869,116 - 102,869,117RGD_MAPPER_PIPELINEGRCh38
GRCh3710104,628,873 - 104,628,874RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS746734_HHumantotal reticulocyte count  IAGPrs7085104405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS746734_HHumanreticulocyte count  IAGPrs7085104405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7365766BORCS7-ASMTBORCS7-ASMT readthrough (NMD candidate)10102854210102901899Human

Position Markers

Peak: (rs7085104)
Human AssemblyChrPosition (strand)Source
GRCh3810102,869,116 - 102,869,117RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407099345GWAS748321_Hschizophrenia QTL GWAS748321 (human)4e-13schizophrenia10102869116102869117Human
2314551GLUCO52_HGlucose level QTL 52 (human)1.4Glucose level1077605006103605006Human
407107190GWAS756166_Hschizophrenia QTL GWAS756166 (human)2e-18schizophrenia10102869116102869117Human
407098043GWAS747019_Hschizophrenia QTL GWAS747019 (human)3e-15schizophrenia10102869116102869117Human
407098298GWAS747274_Hobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa QTL GWAS747274 (human)3e-16obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa10102869116102869117Human
407097758GWAS746734_Hreticulocyte count QTL GWAS746734 (human)4e-11reticulocyte counttotal reticulocyte count (CMO:0003020)10102869116102869117Human
407096205GWAS745181_Hschizophrenia QTL GWAS745181 (human)1e-17schizophrenia10102869116102869117Human
407098252GWAS747228_Hschizophrenia QTL GWAS747228 (human)2e-16schizophrenia10102869116102869117Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS745181_H GCST007201 Schizophrenia 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls A NR 1E-17 17 rs7085104 1.1025358 PMID:30285260
GWAS746734_H GCST004628 Immature fraction of reticulocytes 170,548 European ancestry individuals G 0.3292 4E-11 10.398 rs7085104 0.02494309 reticulocyte count (EFO:0007986)
PMID:27863252
GWAS747019_H GCST010645 Schizophrenia (MTAG) 65,967 individuals ? NR 3E-15 14.523 rs7085104 N/A PMID:32606422
GWAS747228_H GCST010640 Schizophrenia (MTAG) 67,764 individuals ? NR 2E-16 15.699 rs7085104 N/A PMID:32606422
GWAS748321_H GCST002149 Schizophrenia 5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls A 0.645 4E-13 12.398 rs7085104 1.11 PMID:23974872
GWAS756166_H GCST90020095 Schizophrenia (MTAG) 940,613 European ancestry individuals ? NR 2E-18 17.699 rs7085104 N/A PMID:34159505
None Available GCST009600 Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) 19,009 European ancestry ADHD cases, 3,495 European ancestry anorexia cases, 18,381 European ancestry autism cases, 20,352 European ancestry bipolar disorder cases, 130,664 European ancestry major depression cases, 2,688 European ancestry OCD cases, 33,640 European ancestry schizophrenia cases, 4,645 European ancestry Tourette's cases, 494,162 European ancestry controls ? NR 3E-16 15.523 rs7085104 N/A obsessive-compulsive disorder (EFO:0004242)
attention deficit hyperactivity disorder (EFO:0003888)
Tourette syndrome (EFO:0004895)
autism spectrum disorder (EFO:0003756)
PMID:31835028
Database Acc Id Source(s)
GWAS Catalog GCST004628 GWAS Catalog

RGD Curation Notes
Note Type Note Reference