GWAS742382_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS742382_H (low density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS742382 (human)) Homo sapiens

Symbol: GWAS742382_H
Name: low density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS742382 (human)
RGD ID: 407093406
Trait: low density lipoprotein cholesterol measurement, alcohol drinking
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 1.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38976,130,261 - 76,130,262RGD_MAPPER_PIPELINEGRCh38
GRCh37978,745,177 - 78,745,178RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS742382_HHumanblood low density lipoprotein cholesterol level  IAGPrs7035578405850206Based on the EFO term IDGWAS_CATALOGPMID:30698716

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS742382_HHumanalcohol drinking  IAGPrs7035578405850206 GWAS_CATALOGPMID:30698716
GWAS742382_HHumanlow density lipoprotein cholesterol measurement  IAGPrs7035578405850206 GWAS_CATALOGPMID:30698716

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
732125PCSK5proprotein convertase subtilisin/kexin type 597588980976362975Human


Peak: (rs7035578)
Human AssemblyChrPosition (strand)Source
GRCh38976,130,261 - 76,130,262RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
407084057GWAS733033_Hlow density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS733033 (human)9e-09low density lipoprotein cholesterol measurement, alcohol drinkingblood low density lipoprotein cholesterol level (CMO:0000053)97613026176130262Human
407093406GWAS742382_Hlow density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS742382 (human)1e-09low density lipoprotein cholesterol measurement, alcohol drinkingblood low density lipoprotein cholesterol level (CMO:0000053)97613026176130262Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS742382_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers A NR 1E-9 9 rs7035578 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS1713727_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers A NR 6E-9 8.222 rs7035578 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS1713907_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers A NR 3E-8 7.523 rs7035578 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS733033_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers A NR 9E-9 8.046 rs7035578 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
Database
Acc Id
Source(s)
GWAS Catalog GCST008079 GWAS Catalog

Note Type Note Reference