GWAS721867_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS721867_H (testosterone measurement QTL GWAS721867 (human)) Homo sapiens

Symbol: GWAS721867_H
Name: testosterone measurement QTL GWAS721867 (human)
RGD ID: 407072891
Trait: testosterone measurement
Measurement Type: serum testosterone level   (CMO:0000568)    
LOD Score: Not Available
P Value: 1.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810102,863,296 - 102,863,297RGD_MAPPER_PIPELINEGRCh38
GRCh3710104,623,053 - 104,623,054RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS721867_HHumanserum testosterone level  IAGPrs11191421405850206Based on the EFO term IDGWAS_CATALOGPMID:36653534

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS721867_HHumantestosterone measurement  IAGPrs11191421405850206 GWAS_CATALOGPMID:36653534
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7365766BORCS7-ASMTBORCS7-ASMT readthrough (NMD candidate)10102854210102901899Human
1323417BORCS7BLOC-1 related complex subunit 710102854259102864961Human

Position Markers

Peak: (rs11191421)
Human AssemblyChrPosition (strand)Source
GRCh3810102,863,296 - 102,863,297RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407020787GWAS669763_Htestosterone measurement QTL GWAS669763 (human)7e-21testosterone measurementserum testosterone level (CMO:0000568)10102863296102863297Human
407179495GWAS828471_Htestosterone measurement QTL GWAS828471 (human)4e-31testosterone measurementserum testosterone level (CMO:0000568)10102863296102863297Human
407160087GWAS809063_Htestosterone measurement QTL GWAS809063 (human)8e-12testosterone measurementserum testosterone level (CMO:0000568)10102863296102863297Human
2314551GLUCO52_HGlucose level QTL 52 (human)1.4Glucose level1077605006103605006Human
407158961GWAS807937_Htestosterone measurement QTL GWAS807937 (human)6e-19testosterone measurementserum testosterone level (CMO:0000568)10102863296102863297Human
407157955GWAS806931_Htestosterone measurement QTL GWAS806931 (human)7e-19testosterone measurementserum testosterone level (CMO:0000568)10102863296102863297Human
407072891GWAS721867_Htestosterone measurement QTL GWAS721867 (human)1e-18testosterone measurementserum testosterone level (CMO:0000568)10102863296102863297Human
407033036GWAS682012_Hfree androgen index QTL GWAS682012 (human)3e-16free androgen index10102863296102863297Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS669763_H GCST90239820 Total testosterone levels 174,850 British ancestry women ? NR 7E-21 20.155 rs11191421 0.036537 testosterone measurement (EFO:0004908)
 PMID:36653534
GWAS682012_H GCST90239824 Free androgen index 158,208 British ancestry women ? NR 3E-16 15.523 rs11191421 0.0329086 free androgen index (EFO:0007005)
 PMID:36653534
GWAS721867_H GCST90239826 Free testosterone levels 158,089 British ancestry women ? NR 1E-18 18 rs11191421 0.0358311 testosterone measurement (EFO:0004908)
 PMID:36653534
GWAS806931_H GCST90104296 Testosterone levels 4,229 African ancestry individuals, 182,648 European ancestry individuals ? NR 7E-19 18.155 rs11191421 8.877 testosterone measurement (EFO:0004908)
 PMID:35192695
GWAS807937_H GCST90104272 Testosterone levels 182,648 European ancestry individuals G 0.236102 6E-19 18.222 rs11191421 0.0344424 testosterone measurement (EFO:0004908)
 PMID:35192695
GWAS809063_H GCST90104276 Testosterone levels in postmenopausal women 84,003 European ancestry individuals G 0.236102 8E-12 11.097 rs11191421 0.0389811 testosterone measurement (EFO:0004908)
 PMID:35192695
GWAS828471_H GCST90012112 Total testosterone levels 230,454 European ancestry women C 0.758129 4E-31 30.398 rs11191421 0.0374361 testosterone measurement (EFO:0004908)
 PMID:32042192
Database Acc Id Source(s)
GWAS Catalog GCST90239826 GWAS Catalog

RGD Curation Notes
Note Type Note Reference