GWAS711662_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS711662_H (low density lipoprotein cholesterol measurement, body fat percentage QTL GWAS711662 (human)) Homo sapiens

Symbol: GWAS711662_H
Name: low density lipoprotein cholesterol measurement, body fat percentage QTL GWAS711662 (human)
RGD ID: 407062686
Trait: low density lipoprotein cholesterol measurement, body fat percentage
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
body fat percentage   (CMO:0000302)    
LOD Score: Not Available
P Value: 5.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386160,351,810 - 160,351,811RGD_MAPPER_PIPELINEGRCh38
GRCh376160,772,842 - 160,772,843RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS711662_HHumanblood low density lipoprotein cholesterol level  IAGPrs539958405850206Based on the EFO term IDGWAS_CATALOGPMID:33619380
GWAS711662_HHumanbody fat percentage  IAGPrs539958405850206Based on the EFO term IDGWAS_CATALOGPMID:33619380

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS711662_HHumanbody fat percentage  IAGPrs539958405850206 GWAS_CATALOGPMID:33619380
GWAS711662_HHumanlow density lipoprotein cholesterol measurement  IAGPrs539958405850206 GWAS_CATALOGPMID:33619380
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1351828SLC22A3solute carrier family 22 member 36160348378160452577Human

Position Markers

Peak: (rs539958)
Human AssemblyChrPosition (strand)Source
GRCh386160,351,810 - 160,351,811RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407062418GWAS711394_Hbody mass index, coronary artery disease QTL GWAS711394 (human)3e-10body mass index, coronary artery diseasebody mass index (BMI) (CMO:0000105)6160351810160351811Human
407062064GWAS711040_Htriglyceride measurement, body fat percentage QTL GWAS711040 (human)2e-12triglyceride measurement, body fat percentagebody fat percentage (CMO:0000302)6160351810160351811Human
407063536GWAS712512_Htriglyceride measurement, body mass index QTL GWAS712512 (human)1e-14triglyceride measurement, body mass indexbody mass index (BMI) (CMO:0000105)6160351810160351811Human
407286133GWAS935109_Hbody height QTL GWAS935109 (human)2e-197body height (VT:0001253)body height (CMO:0000106)6160351810160351811Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
407062111GWAS711087_Hsystolic blood pressure, body mass index QTL GWAS711087 (human)7e-10systolic blood pressure, body mass indexbody mass index (BMI) (CMO:0000105)6160351810160351811Human
407062686GWAS711662_Hlow density lipoprotein cholesterol measurement, body fat percentage QTL GWAS711662 (human)5e-10low density lipoprotein cholesterol measurement, body fat percentagebody fat percentage (CMO:0000302)6160351810160351811Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human
407063229GWAS712205_Hlow density lipoprotein cholesterol measurement, body mass index QTL GWAS712205 (human)2e-11low density lipoprotein cholesterol measurement, body mass indexbody mass index (BMI) (CMO:0000105)6160351810160351811Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS711040_H GCST011342 Body fat percentage and triglycerides (pairwise) 268,505 European ancestry individuals, 10,072 East Asian, South Asian and African American ancestry individuals T 0.4831 2E-12 11.699 rs539958 N/A triglyceride measurement (EFO:0004530)
body fat percentage (EFO:0007800)
 PMID:33619380
GWAS711087_H GCST011331 Body mass index and systole blood pressure (pairwise) 472,402 European ancestry individuals, 16,962 East Asian, South Asian, Hispanic and African American ancestry individuals T 0.4831 7E-10 9.155 rs539958 N/A systolic blood pressure (EFO:0006335)
body mass index (EFO:0004340)
 PMID:33619380
GWAS711394_H GCST011330 Body mass index and coronary artery disease (pairwise) 464,176 European ancestry individuals, 59,353 East Asian, South Asian, Hispanic and African American ancestry individuals T 0.4831 3E-10 9.523 rs539958 N/A body mass index (EFO:0004340)
coronary artery disease (EFO:0001645)
 PMID:33619380
GWAS711662_H GCST011343 Body fat percentage and LDL-C (pairwise) 263,726 European ancestry individuals, 10,061 East Asian, South Asian and African American ancestry individuals T 0.4831 5E-10 9.302 rs539958 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
body fat percentage (EFO:0007800)
 PMID:33619380
GWAS712205_H GCST011335 Body mass index and LDL-C (pairwise) 495,344 European ancestry individuals,16,962 East Asian, South Asian, Hispanic and African American ancestry individuals T 0.4831 2E-11 10.699 rs539958 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
body mass index (EFO:0004340)
 PMID:33619380
GWAS712512_H GCST011334 Body mass index and triglycerides (pairwise) 500,123 European ancestry individuals,16,962 East Asian, South Asian, Hispanic and African American ancestry individuals T 0.4831 1E-14 14 rs539958 N/A triglyceride measurement (EFO:0004530)
body mass index (EFO:0004340)
 PMID:33619380
GWAS935109_H GCST90245848 Height 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals T 0.4755 2E-197 196.699 rs539958 0.0186 body height (EFO:0004339)
 PMID:36224396
Database Acc Id Source(s)
GWAS Catalog GCST011343 GWAS Catalog

RGD Curation Notes
Note Type Note Reference