GWAS702982_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS702982_H (heel bone mineral density QTL GWAS702982 (human)) Homo sapiens

Symbol: GWAS702982_H
Name: heel bone mineral density QTL GWAS702982 (human)
RGD ID: 407054006
Trait: heel bone mineral density
Measurement Type: bone mineral density   (CMO:0001226)    
LOD Score: Not Available
P Value: 2.0E-21
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,110,074 - 11,110,075RGD_MAPPER_PIPELINEGRCh38
GRCh37111,170,131 - 11,170,132RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS702982_HHumanbone mineral density  IAGPrs2261434405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS702982_HHumanheel bone mineral density  IAGPrs2261434405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
68533MTORmechanistic target of rapamycin kinase11110653511262551Human


Peak: (rs2261434)
Human AssemblyChrPosition (strand)Source
GRCh38111,110,074 - 11,110,075RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407054006GWAS702982_Hheel bone mineral density QTL GWAS702982 (human)2e-21heel bone mineral densitybone mineral density (CMO:0001226)11111007411110075Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS702982_H GCST007066 Heel bone mineral density approximately 446,000 European ancestry individuals ? NR 2E-21 20.699 rs2261434 N/A heel bone mineral density (EFO:0009270)
 PMID:30595370
GWAS1775342_H GCST90245846 Height 293,593 African ancestry individuals A 0.76309 4E-9 8.398 rs2261434 0.02298 body height (OBA:VT0001253)
 PMID:36224396
Database
Acc Id
Source(s)
GWAS Catalog GCST007066 GWAS Catalog

Note Type Note Reference