GWAS689998_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS689998_H (body mass index QTL GWAS689998 (human)) Homo sapiens

Symbol: GWAS689998_H
Name: body mass index QTL GWAS689998 (human)
RGD ID: 407041022
Trait: body mass index
Measurement Type: body mass index (BMI)   (CMO:0000105)    
LOD Score: Not Available
P Value: 9.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,224,279 - 11,224,280RGD_MAPPER_PIPELINEGRCh38
GRCh37111,284,336 - 11,284,337RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS689998_HHumanbody mass index (BMI)  IAGPrs10779751405850206Based on the EFO term IDGWAS_CATALOGPMID:25673413

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS689998_HHumanbody mass index  IAGPrs10779751405850206 GWAS_CATALOGPMID:25673413
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
68533MTORmechanistic target of rapamycin kinase11110653511262551Human

Position Markers

Peak: (rs10779751)
Human AssemblyChrPosition (strand)Source
GRCh38111,224,279 - 11,224,280RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406949168GWAS598144_Hbody mass index QTL GWAS598144 (human)0.000002body mass indexbody mass index (BMI) (CMO:0000105)11122427911224280Human
406973669GWAS622645_Hbody mass index QTL GWAS622645 (human)2e-13body mass indexbody mass index (BMI) (CMO:0000105)11122427911224280Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407041022GWAS689998_Hbody mass index QTL GWAS689998 (human)0.000009body mass indexbody mass index (BMI) (CMO:0000105)11122427911224280Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407047228GWAS696204_Hbody mass index QTL GWAS696204 (human)6e-14body mass indexbody mass index (BMI) (CMO:0000105)11122427911224280Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS598144_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals A 0.29 0.000002 5.699 rs10779751 0.016 body mass index (EFO:0004340)
 PMID:25673413
GWAS622645_H GCST90179150 Body mass index (MTAG) 694,649 European ancestry individuals A NR 2E-13 12.699 rs10779751 0.013128 body mass index (EFO:0004340)
 PMID:36376304
GWAS689998_H GCST002783 Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals A 0.277 0.000009 5.046 rs10779751 0.015 body mass index (EFO:0004340)
 PMID:25673413
GWAS696204_H GCST90255621 Body mass index 1,122,049 European ancestry individuals G NR 6E-14 13.222 rs10779751 0.0123 body mass index (EFO:0004340)
 PMID:36581621
None Available GCST90446645 Body mass index 650,000 European ancestry individuals A 0.2789 2E-12 11.699 rs10779751 0.0136 body mass index (EFO:0004340)
 PMID:39375568
Database Acc Id Source(s)
GWAS Catalog GCST002783 GWAS Catalog

RGD Curation Notes
Note Type Note Reference