GWAS622969_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS622969_H (QRS complex, QRS duration QTL GWAS622969 (human)) Homo sapiens

Symbol: GWAS622969_H
Name: QRS complex, QRS duration QTL GWAS622969 (human)
RGD ID: 406973993
Trait: QRS complex, QRS duration
Measurement Type: QRS duration   (CMO:0000267)    
LOD Score: Not Available
P Value: 3.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3813,342,619 - 3,342,620RGD_MAPPER_PIPELINEGRCh38
GRCh3713,259,183 - 3,259,184RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS622969_HHumanQRS duration  IAGPrs6683273405850206Based on the EFO term IDGWAS_CATALOGPMID:27659466

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS622969_HHumanQRS complex  IAGPrs6683273405850206 GWAS_CATALOGPMID:27659466
GWAS622969_HHumanQRS duration  IAGPrs6683273405850206 GWAS_CATALOGPMID:27659466
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
QRS duration  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1353101PRDM16PR/SET domain 16130692033438621Human

Position Markers

Peak: (rs6683273)
Human AssemblyChrPosition (strand)Source
GRCh3813,342,619 - 3,342,620RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
406973993GWAS622969_HQRS complex, QRS duration QTL GWAS622969 (human)3e-08QRS complex, QRS durationQRS duration (CMO:0000267)133426193342620Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS622969_H GCST003844 QRS duration 59,565 European ancestry individuals, 690 Orcadian (founder/genetic isolate) individuals ? NR 3E-8 7.523 rs6683273 N/A QRS complex (EFO:0005054)
QRS duration (EFO:0005055)
 PMID:27659466
Database Acc Id Source(s)
GWAS Catalog GCST003844 GWAS Catalog

RGD Curation Notes
Note Type Note Reference