Vertebrate Trait Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | GWAS578228_H | Human | blood lipid amount | | IAGP | rs11591147 | 405850206 | Based on the EFO term ID | GWAS_CATALOG | PMID:35213538 | |
|
Vertebrate Trait Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | GWAS578228_H | Human | blood lipid amount | | IAGP | rs11591147 | 405850206 | Based on the EFO term ID | GWAS_CATALOG | PMID:35213538 | |
|
# | Reference Title | Reference Citation |
1. | RGD GWAS Catalog Import Pipeline | RGD pipeline to import data from GWAS Catalog and create human variant and QTL records |
The following Genes overlap with this region. | Full Report | CSV | TAB | Printer | Analysis Tools |
Peak: (rs11591147) |
|
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
Data has come from the GWAS Catalog | ||
The highlighted row represents the current QTL |
QTL | GWAS Catalog Study | Disease Trait | Study Size | Risk Allele | Risk Allele Frequency | P Value | P Value MLOG | Peak Marker | Reported Odds Ratio or Beta-coefficient | Ontology Accession | PubMed |
GWAS553241_H | GCST90244655 | Total cholesterol levels | 29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals | ? | NR | 2E-67 | 66.699 | rs11591147 | 22.988142 | total cholesterol measurement (EFO:0004574) |
PMID:36220816 |
GWAS553456_H | GCST90244653 | Low density lipoprotein cholesterol levels | 29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals | ? | NR | 6E-78 | 77.222 | rs11591147 | 22.96128 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36220816 |
GWAS554635_H | GCST90245141 | Cholesterol levels | 14,296 European ancestry individuals | T | 0.018 | 1E-15 | 15 | rs11591147 | 0.3054436 | total cholesterol measurement (EFO:0004574) |
PMID:36357675 |
GWAS558568_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.987 | 6E-70 | 69.222 | rs11591147 | 0.475 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS558569_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.989 | 2E-12 | 11.699 | rs11591147 | 0.507 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS558606_H | GCST007141 | Low density lipoprotein cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | NR | 3E-12 | 11.523 | rs11591147 | 0.493 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:29507422 |
GWAS566442_H | GCST008676 | LDL cholesterol levels | up to 23,353 African ancestry individuals, 13,171 Asian ancestry individuals, up to 82,522 European ancestry individuals, 6,646 Hispanic individuals | T | 0.0159 | 1E-51 | 51 | rs11591147 | 14.3865 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30926973 |
GWAS566810_H | GCST010245 | LDL cholesterol levels | 440,546 European ancestry individuals | G | 0.982532 | 2E-421 | 420.699 | rs11591147 | 0.348511 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:32203549 |
GWAS569977_H | GCST010204 | Low density lipoprotein cholesterol levels | 324,708 British ancestry individuals | ? | NR | 3E-563 | 562.523 | rs11591147 | 0.4704 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:32154731 |
GWAS572460_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 1E-8 | 8 | rs11591147 | 0.0835896 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS572461_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 2E-8 | 7.699 | rs11591147 | 0.08388951 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS572529_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 3E-8 | 7.523 | rs11591147 | 0.08225315 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS573175_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000001 | 6 | rs11591147 | 0.072261296 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000001 | 6 | rs11591147 | 0.0714336 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS573189_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000002 | 5.699 | rs11591147 | 0.07026635 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS573408_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 8E-16 | 15.097 | rs11591147 | 0.101447664 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS573411_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-17 | 17 | rs11591147 | 0.10599908 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS573439_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-16 | 16 | rs11591147 | 0.066919476 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS574029_H | GCST007284 | LDL cholesterol x physical activity interaction (2df test) | 7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals | T | 0.0194 | 6E-158 | 157.222 | rs11591147 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) physical activity (EFO:0003940) |
PMID:30670697 |
GWAS574139_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-14 | 13.699 | rs11591147 | 0.07545552 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS574140_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-24 | 24 | rs11591147 | 0.0731577 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS574710_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 3E-23 | 22.523 | rs11591147 | 0.07225063 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS574744_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 4E-9 | 8.398 | rs11591147 | 0.07191426 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 3E-8 | 7.523 | rs11591147 | 0.08128867 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS575226_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 9E-8 | 7.046 | rs11591147 | 0.07932203 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS575331_H | GCST006284 | Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease | 2,022 European ancestry individuals without statin treatment, 1,268 European ancestry individuals with statin treatment | T | 0.0121655389057751 | 2E-17 | 16.699 | rs11591147 | 0.315 | PCSK9 protein measurement (EFO:0006899) |
PMID:29748315 |
GWAS575408_H | GCST006284 | Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease | 2,022 European ancestry individuals without statin treatment, 1,268 European ancestry individuals with statin treatment | T | 0.0123626399604352 | 6E-16 | 15.222 | rs11591147 | 0.374259 | PCSK9 protein measurement (EFO:0006899) |
PMID:29748315 |
GWAS575686_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 2E-10 | 9.699 | rs11591147 | 0.09421623 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS575701_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 3E-10 | 9.523 | rs11591147 | 0.09339385 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576006_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 7E-25 | 24.155 | rs11591147 | 0.08232603 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576072_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-20 | 19.398 | rs11591147 | 0.067575164 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576171_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 4E-11 | 10.398 | rs11591147 | 0.09737745 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576174_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 6E-11 | 10.222 | rs11591147 | 0.09691767 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-17 | 16.699 | rs11591147 | 0.074171774 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576584_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-19 | 18.699 | rs11591147 | 0.054627746 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576589_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 5E-11 | 10.302 | rs11591147 | 0.055473983 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-16 | 16 | rs11591147 | 0.05168364 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576656_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-13 | 12.699 | rs11591147 | 0.053519048 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576688_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000007 | 5.155 | rs11591147 | 0.06626444 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS576691_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 4E-13 | 12.398 | rs11591147 | 0.107789345 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 4E-13 | 12.398 | rs11591147 | 0.107046075 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577450_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-22 | 21.398 | rs11591147 | 0.06969179 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577452_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 3E-13 | 12.523 | rs11591147 | 0.090329915 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577463_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 7E-26 | 25.155 | rs11591147 | 0.08650212 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577514_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 3E-17 | 16.523 | rs11591147 | 0.070111126 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577518_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 9E-11 | 10.046 | rs11591147 | 0.05538142 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577611_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 5E-17 | 16.302 | rs11591147 | 0.09798073 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577682_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-21 | 20.699 | rs11591147 | 0.10510873 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577688_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 3E-21 | 20.523 | rs11591147 | 0.101035945 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS577750_H | GCST010243 | Apolipoprotein B levels | 439,214 European ancestry individuals | G | 0.982548 | 3E-418 | 417.523 | rs11591147 | 0.345975 | apolipoprotein B measurement (EFO:0004615) |
PMID:32203549 |
None Available | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-24 | 24 | rs11591147 | 0.093113914 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS578196_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-23 | 22.398 | rs11591147 | 0.09172767 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS578228_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-10 | 10 | rs11591147 | 0.049240064 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS578310_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 5E-18 | 17.302 | rs11591147 | 0.06261891 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS578312_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-17 | 16.398 | rs11591147 | 0.06315279 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS578314_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 7E-20 | 19.155 | rs11591147 | 0.06511056 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS578322_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-16 | 15.699 | rs11591147 | 0.07088224 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS579910_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 9E-16 | 15.046 | rs11591147 | 0.06311606 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS580149_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-16 | 15.398 | rs11591147 | 0.07213569 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS580361_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 8E-20 | 19.097 | rs11591147 | 0.066583015 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 6E-11 | 10.222 | rs11591147 | 0.049032982 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS580702_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-18 | 18 | rs11591147 | 0.07048526 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS580704_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 5E-20 | 19.302 | rs11591147 | 0.06443847 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS580707_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 2E-18 | 17.699 | rs11591147 | 0.05720689 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS581332_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-10 | 9.398 | rs11591147 | 0.076375164 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS581430_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 3E-16 | 15.523 | rs11591147 | 0.09282211 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS581441_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 1E-12 | 12 | rs11591147 | 0.06434394 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS583316_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-12 | 11.398 | rs11591147 | 0.079863556 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS583391_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 9E-18 | 17.046 | rs11591147 | 0.0823401 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 4E-20 | 19.398 | rs11591147 | 0.09586883 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS584306_H | GCST009240 | Serum metabolite levels (CMS) | 6,263 Finnish ancestry men | ? | NR | 8E-19 | 18.097 | rs11591147 | 0.09666114 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS605614_H | GCST002898 | LDL cholesterol | up 62,166 European ancestry individuals | G | 0.98 | 2E-92 | 91.699 | rs11591147 | 0.528 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:25961943 |
None Available | GCST004209 | Cholesterol, total | 19,259 British ancestry individuals from 6863 families. | T | 0.0169 | 2E-17 | 16.699 | rs11591147 | 0.36090583 | total cholesterol measurement (EFO:0004574) |
PMID:28270201 |
GWAS619005_H | GCST90248898 | Proprotein convertase subtilisin/kexin type 9 levels | 10,708 European ancestry individuals | T | 0.02 | 2E-64 | 63.699 | rs11591147 | 0.883 | proprotein convertase subtilisin/kexin type 9 measurement (EFO:0009312) |
PMID:34648354 |
None Available | GCST011365 | Myocardial infarction | 14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls | G | 0.984027 | 2E-16 | 15.699 | rs11591147 | 1.34 | myocardial infarction (EFO:0000612) |
PMID:33532862 |
GWAS630257_H | GCST011364 | Myocardial infarction | 14,825 European ancestry cases, 2,680 cases, 380,970 European ancestry controls, 73,242 controls | G | 0.983216 | 8E-11 | 10.097 | rs11591147 | 1.31 | myocardial infarction (EFO:0000612) |
PMID:33532862 |
GWAS637004_H | GCST008037 | Low density lipoprotein cholesterol levels | 9,720 African American individuals, 17,373 Hispanic/Latino individuals, 2,316 Asian ancestry individuals, 1,900 Native Hawaiian ancestry individuals, 591 Native American ancestry individuals, 321 individuals | ? | NR | 4E-32 | 31.398 | rs11591147 | 21.51406 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:31217584 |
GWAS638043_H | GCST008045 | Total cholesterol levels | 10,137 African American individuals, 17,802 Hispanic/Latino individuals, 2,387 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals | ? | NR | 9E-25 | 24.046 | rs11591147 | 21.17191 | total cholesterol measurement (EFO:0004574) |
PMID:31217584 |
GWAS642131_H | GCST011346 | Total cholesterol levels | 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals | ? | NR | 2E-59 | 58.699 | rs11591147 | 0.4533 | total cholesterol measurement (EFO:0004574) |
PMID:33339817 |
None Available | GCST011347 | Low density lipoprotein cholesterol levels | 76,081 European ancestry individuals, 127,395 Japanese ancestry individuals | ? | NR | 2E-67 | 66.699 | rs11591147 | 0.4795 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:33339817 |
None Available | GCST011495 | Abdominal aortic aneurysm | 7,642 European ancestry cases, 172,172 European ancestry controls | G | 0.9839 | 6E-11 | 10.222 | rs11591147 | 1.58 | Abdominal Aortic Aneurysm (EFO:0004214) |
PMID:32981348 |
GWAS659539_H | GCST006612 | LDL cholesterol | 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals | T | 0.0149 | 3E-257 | 256.523 | rs11591147 | 0.3952 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30275531 |
GWAS660293_H | GCST006614 | Total cholesterol levels | 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals | T | 0.015 | 8E-175 | 174.097 | rs11591147 | 0.325 | total cholesterol measurement (EFO:0004574) |
PMID:30275531 |
GWAS663395_H | GCST007931 | Medication use (HMG CoA reductase inhibitors) | 73,475 European ancestry cases, 216,910 European ancestry controls | T | 0.017203 | 9E-64 | 63.046 | rs11591147 | 0.362324 | HMG CoA reductase inhibitor use measurement (EFO:0009932) |
PMID:31015401 |
GWAS665244_H | GCST007848 | LDL cholesterol | up to 42,208 European ancestry individuals, up to 14,330 African ancestry individuals | ? | 0.0154 | 3E-59 | 58.523 | rs11591147 | 17.0 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:24507774 |
GWAS672293_H | GCST90269684 | Free cholesterol to total lipids in very large VLDL percentage (UKB data field 23587) | 87,620 European ancestry individuals | T | 0.0172506 | 5E-35 | 34.302 | rs11591147 | 0.217578 | free cholesterol to total lipids in very large VLDL percentage (EFO:0022289) |
PMID:36764567 |
GWAS672458_H | GCST90269687 | Cholesterol to total lipids in large VLDL percentage (UKB data field 23590) | 88,321 European ancestry individuals | T | 0.0173288 | 9E-42 | 41.046 | rs11591147 | 0.240473 | cholesterol to total lipids in large VLDL percentage (EFO:0022236) |
PMID:36764567 |
GWAS672581_H | GCST90269685 | Triglycerides to total lipids in very large VLDL percentage (UKB data field 23588) | 87,620 European ancestry individuals | T | 0.0172506 | 5E-45 | 44.302 | rs11591147 | 0.24845 | triglycerides to total lipids in very large VLDL percentage (EFO:0022340) |
PMID:36764567 |
GWAS672900_H | GCST90269683 | Cholesteryl esters to total lipids in very large VLDL percentage (UKB data field 23586) | 87,620 European ancestry individuals | T | 0.0172506 | 1E-32 | 32 | rs11591147 | 0.207503 | cholesteryl esters to total lipids in very large VLDL percentage (EFO:0022258) |
PMID:36764567 |
GWAS673587_H | GCST90269705 | Triglycerides to total lipids in very small VLDL percentage (UKB data field 23608) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-52 | 51.398 | rs11591147 | 0.262392 | triglycerides to total lipids in very small VLDL percentage (EFO:0022341) |
PMID:36764567 |
None Available | GCST90269704 | Free cholesterol to total lipids in very small VLDL percentage (UKB data field 23607) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-51 | 51 | rs11591147 | 0.273122 | free cholesterol to total lipids in very small VLDL percentage (EFO:0022290) |
PMID:36764567 |
GWAS674913_H | GCST000134 | LDL cholesterol | 2,758 European ancestry individuals | T | 0.01 | 2E-44 | 43.699 | rs11591147 | 0.47 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:18193044 |
GWAS678426_H | GCST90269502 | LDL cholesterol levels (UKB data field 23405) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-65 | 64.302 | rs11591147 | 0.307335 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
None Available | GCST90277245 | Sterol ester (27:1/18:1) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 2E-10 | 9.699 | rs11591147 | 0.298324 | PMID:37907536 | |
None Available | GCST90277246 | Sterol ester (27:1/18:2) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 2E-14 | 13.699 | rs11591147 | 0.358123 | PMID:37907536 | |
None Available | GCST90277240 | Sterol ester (27:1/16:0) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 5E-17 | 16.302 | rs11591147 | 0.390076 | PMID:37907536 | |
GWAS678749_H | GCST90269620 | Concentration of IDL particles (UKB data field 23523) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-85 | 84.523 | rs11591147 | 0.350591 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:36764567 |
GWAS679066_H | GCST90269617 | Cholesteryl esters in very small VLDL (UKB data field 23520) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-75 | 74.302 | rs11591147 | 0.320411 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS679372_H | GCST90269618 | Free cholesterol in very small VLDL (UKB data field 23521) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-61 | 61 | rs11591147 | 0.294005 | free cholesterol in very small VLDL measurement (EFO:0022275) |
PMID:36764567 |
None Available | GCST90269652 | Cholesteryl esters in very large HDL (UKB data field 23555) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-16 | 15.699 | rs11591147 | 0.135774 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
None Available | GCST90269514 | Cholesteryl esters in LDL (UKB data field 23417) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-59 | 58.699 | rs11591147 | 0.293904 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS679575_H | GCST90302117 | Total cholines levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-60 | 59.699 | rs11591147 | 0.2394 | choline measurement (EFO:0010116) |
PMID:38448586 |
None Available | GCST90269529 | Average diameter for LDL particles (UKB data field 23432) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-17 | 16.699 | rs11591147 | 0.14952 | low density lipoprotein particle size measurement (EFO:0008593) |
PMID:36764567 |
None Available | GCST90269649 | Total lipids in very large HDL (UKB data field 23552) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-13 | 12.699 | rs11591147 | 0.121125 | total lipids in very large HDL measurement (EFO:0022312) |
PMID:36764567 |
GWAS679967_H | GCST90269616 | Cholesterol in very small VLDL (UKB data field 23519) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-72 | 72 | rs11591147 | 0.316515 | cholesterol in very small VLDL measurement (EFO:0022231) |
PMID:36764567 |
GWAS680230_H | GCST90269621 | Total lipids in IDL (UKB data field 23524) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-78 | 77.523 | rs11591147 | 0.328522 | total lipids in IDL (EFO:0022161) |
PMID:36764567 |
GWAS680496_H | GCST90269653 | Free cholesterol in very large HDL (UKB data field 23556) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-29 | 28.302 | rs11591147 | 0.190158 | free cholesterol in very large HDL measurement (EFO:0022273) |
PMID:36764567 |
GWAS680859_H | GCST90269516 | Total free cholesterol levels (UKB data field 23419) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-60 | 59.523 | rs11591147 | 0.290144 | free cholesterol measurement (EFO:0008591) |
PMID:36764567 |
GWAS680986_H | GCST90269501 | Clinical LDL cholesterol levels (UKB data field 23404) | 88,329 European ancestry individuals | T | 0.0173273 | 8E-74 | 73.097 | rs11591147 | 0.327715 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS681065_H | GCST90302111 | Concentration of small VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 7E-21 | 20.155 | rs11591147 | 0.1364 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90269651 | Cholesterol in very large HDL (UKB data field 23554) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-19 | 18.699 | rs11591147 | 0.149168 | cholesterol in very large HDL measurement (EFO:0022229) |
PMID:36764567 |
GWAS681492_H | GCST90302112 | Phospholipids in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 4E-21 | 20.398 | rs11591147 | 0.1373 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:38448586 |
GWAS681941_H | GCST90269518 | Free cholesterol in LDL (UKB data field 23421) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-76 | 75.302 | rs11591147 | 0.331354 | free cholesterol in LDL measurement (EFO:0022266) |
PMID:36764567 |
GWAS682457_H | GCST90269526 | Concentration of LDL particles (UKB data field 23429) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-69 | 68.699 | rs11591147 | 0.31906 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS682552_H | GCST90269642 | Total lipids in small LDL (UKB data field 23545) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-63 | 62.699 | rs11591147 | 0.304821 | total lipids in small LDL (EFO:0022168) |
PMID:36764567 |
GWAS682893_H | GCST90302119 | Total phosphoglycerides levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 6E-41 | 40.222 | rs11591147 | 0.1958 | phosphoglycerides measurement (EFO:0022291) |
PMID:38448586 |
GWAS683124_H | GCST90269615 | Phospholipids in very small VLDL (UKB data field 23518) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-48 | 47.699 | rs11591147 | 0.260167 | phospholipids in very small VLDL measurement (EFO:0022300) |
PMID:36764567 |
None Available | GCST90269641 | Concentration of small LDL particles (UKB data field 23544) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-59 | 58.699 | rs11591147 | 0.294658 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS683465_H | GCST90269638 | Cholesteryl esters in medium LDL (UKB data field 23541) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-44 | 44 | rs11591147 | 0.254639 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS683770_H | GCST90269639 | Free cholesterol in medium LDL (UKB data field 23542) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-67 | 66.302 | rs11591147 | 0.31334 | free cholesterol in medium LDL measurement (EFO:0022268) |
PMID:36764567 |
GWAS683909_H | GCST90269648 | Concentration of very large HDL particles (UKB data field 23551) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-19 | 19 | rs11591147 | 0.149474 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:36764567 |
GWAS684166_H | GCST90269512 | Total esterified cholesterol levels (UKB data field 23415) | 88,329 European ancestry individuals | T | 0.0173273 | 9E-56 | 55.046 | rs11591147 | 0.275524 | esterified cholesterol measurement (EFO:0008589) |
PMID:36764567 |
GWAS684190_H | GCST90269610 | Cholesteryl esters in small VLDL (UKB data field 23513) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-44 | 43.302 | rs11591147 | 0.251957 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS684502_H | GCST90269609 | Cholesterol in small VLDL (UKB data field 23512) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-49 | 48.699 | rs11591147 | 0.267991 | cholesterol in small VLDL measurement (EFO:0022228) |
PMID:36764567 |
GWAS684833_H | GCST90269646 | Free cholesterol in small LDL (UKB data field 23549) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-75 | 75 | rs11591147 | 0.333343 | free cholesterol in small LDL measurement (EFO:0022271) |
PMID:36764567 |
GWAS685237_H | GCST90269498 | Total cholesterol minus HDL-C levels (UKB data field 23401) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-67 | 67 | rs11591147 | 0.313452 | total cholesterol measurement (EFO:0004574) |
PMID:36764567 |
GWAS685582_H | GCST90269614 | Total lipids in very small VLDL (UKB data field 23517) | 88,329 European ancestry individuals | T | 0.0173273 | 6E-51 | 50.222 | rs11591147 | 0.266407 | total lipids in very small VLDL measurement (EFO:0022156) |
PMID:36764567 |
None Available | GCST90277250 | Sterol ester (27:1/20:4) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 1E-10 | 10 | rs11591147 | 0.297311 | PMID:37907536 | |
GWAS685726_H | GCST90269611 | Free cholesterol in small VLDL (UKB data field 23514) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-57 | 56.699 | rs11591147 | 0.289534 | free cholesterol in small VLDL measurement (EFO:0022272) |
PMID:36764567 |
GWAS685733_H | GCST90269645 | Cholesteryl esters in small LDL (UKB data field 23548) | 88,329 European ancestry individuals | T | 0.0173273 | 8E-54 | 53.097 | rs11591147 | 0.280118 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS685951_H | GCST90269513 | Cholesteryl esters in VLDL (UKB data field 23416) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-51 | 50.302 | rs11591147 | 0.272273 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS685976_H | GCST90302118 | Total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-49 | 48.302 | rs11591147 | 0.2148 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
GWAS686327_H | GCST90269644 | Cholesterol in small LDL (UKB data field 23547) | 88,329 European ancestry individuals | T | 0.0173273 | 9E-63 | 62.046 | rs11591147 | 0.303386 | cholesterol in small LDL measurement (EFO:0022227) |
PMID:36764567 |
GWAS686413_H | GCST90269499 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) levels (UKB data field 23402) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-66 | 65.398 | rs11591147 | 0.30915 | remnant cholesterol measurement (EFO:0010815) |
PMID:36764567 |
None Available | GCST90269643 | Phospholipids in small LDL (UKB data field 23546) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-76 | 75.302 | rs11591147 | 0.33392 | phospholipids in small LDL measurement (EFO:0022297) |
PMID:36764567 |
GWAS687092_H | GCST90269613 | Concentration of very small VLDL particles (UKB data field 23516) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-57 | 56.398 | rs11591147 | 0.28394 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:36764567 |
GWAS687279_H | GCST90269497 | Total cholesterol levels (UKB data field 23400) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-57 | 57 | rs11591147 | 0.281182 | total cholesterol measurement (EFO:0004574) |
PMID:36764567 |
GWAS687390_H | GCST90269602 | Cholesterol in medium VLDL (UKB data field 23505) | 88,329 European ancestry individuals | T | 0.0173273 | 7E-72 | 71.155 | rs11591147 | 0.32402 | cholesterol in medium VLDL measurement (EFO:0022225) |
PMID:36764567 |
None Available | GCST90277370 | Sphingomyelin (d34:1) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 2E-19 | 18.699 | rs11591147 | 0.418933 | PMID:37907536 | |
None Available | GCST90277372 | Sphingomyelin (d36:1) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 3E-8 | 7.523 | rs11591147 | 0.258634 | PMID:37907536 | |
None Available | GCST90277376 | Sphingomyelin (d40:1) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 1E-12 | 12 | rs11591147 | 0.331697 | PMID:37907536 | |
None Available | GCST90277377 | Sphingomyelin (d40:2) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 3E-8 | 7.523 | rs11591147 | 0.259172 | PMID:37907536 | |
GWAS687444_H | GCST90277378 | Sphingomyelin (d42:2) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 8E-15 | 14.097 | rs11591147 | 0.361828 | PMID:37907536 | |
GWAS687490_H | GCST90269535 | Sphingomyelins levels (UKB data field 23438) | 88,268 European ancestry individuals | T | 0.0173336 | 2E-45 | 44.699 | rs11591147 | 0.240039 | sphingomyelin measurement (EFO:0010118) |
PMID:36764567 |
GWAS687538_H | GCST90269634 | Concentration of medium LDL particles (UKB data field 23537) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-50 | 49.699 | rs11591147 | 0.271347 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36764567 |
GWAS687552_H | GCST90269632 | Free cholesterol in large LDL (UKB data field 23535) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-77 | 77 | rs11591147 | 0.33274 | free cholesterol in large LDL measurement (EFO:0022176) |
PMID:36764567 |
GWAS687606_H | GCST90269522 | Total lipids in LDL (UKB data field 23425) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-64 | 63.523 | rs11591147 | 0.30595 | total lipids in LDL measurement (EFO:0022308) |
PMID:36764567 |
GWAS687921_H | GCST90269601 | Phospholipids in medium VLDL (UKB data field 23504) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-42 | 42 | rs11591147 | 0.247288 | phospholipids in medium VLDL measurement (EFO:0022154) |
PMID:36764567 |
GWAS687926_H | GCST90269631 | Cholesteryl esters in large LDL (UKB data field 23534) | 88,329 European ancestry individuals | T | 0.0173273 | 6E-64 | 63.222 | rs11591147 | 0.303448 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS688050_H | GCST90269637 | Cholesterol in medium LDL (UKB data field 23540) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-52 | 51.302 | rs11591147 | 0.275495 | cholesterol in medium LDL measurement (EFO:0022224) |
PMID:36764567 |
GWAS688179_H | GCST90269630 | Cholesterol in large LDL (UKB data field 23533) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-68 | 67.699 | rs11591147 | 0.313709 | cholesterol in large LDL measurement (EFO:0021901) |
PMID:36764567 |
GWAS688522_H | GCST90269608 | Phospholipids in small VLDL (UKB data field 23511) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-40 | 40 | rs11591147 | 0.241076 | phospholipids in small VLDL measurement (EFO:0022146) |
PMID:36764567 |
GWAS689448_H | GCST90269636 | Phospholipids in medium LDL (UKB data field 23539) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-56 | 55.699 | rs11591147 | 0.287122 | phospholipids in medium LDL measurement (EFO:0022183) |
PMID:36764567 |
None Available | GCST90277374 | Sphingomyelin (d38:1) levels | 7,174 Finnish ancestry individuals | T | 0.0332154 | 1E-10 | 10 | rs11591147 | 0.300649 | PMID:37907536 | |
GWAS690221_H | GCST90269603 | Cholesteryl esters in medium VLDL (UKB data field 23506) | 88,329 European ancestry individuals | T | 0.0173273 | 7E-82 | 81.155 | rs11591147 | 0.344177 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
GWAS690242_H | GCST90269628 | Total lipids in large LDL (UKB data field 23531) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-68 | 67.302 | rs11591147 | 0.313025 | total lipids in large LDL (EFO:0022163) |
PMID:36764567 |
GWAS690353_H | GCST90269635 | Total lipids in medium LDL (UKB data field 23538) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-51 | 50.699 | rs11591147 | 0.27401 | total lipids in medium LDL (EFO:0022180) |
PMID:36764567 |
GWAS690669_H | GCST90250902 | Medication use for hyperlipidemia (number of purchases) | 567,671 European ancestry individuals | ? | NR | 2E-215 | 214.699 | rs11591147 | 0.140028 | antihyperlipidemic drug use measurement (EFO:0803367) |
PMID:36653479 |
None Available | GCST90269627 | Concentration of large LDL particles (UKB data field 23530) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-75 | 75 | rs11591147 | 0.332597 | concentration of large LDL particles measurement (EFO:0022160) |
PMID:36764567 |
GWAS690942_H | GCST90269604 | Free cholesterol in medium VLDL (UKB data field 23507) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-52 | 51.699 | rs11591147 | 0.275776 | free cholesterol in medium VLDL measurement (EFO:0022269) |
PMID:36764567 |
GWAS690957_H | GCST90269629 | Phospholipids in large LDL (UKB data field 23532) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-70 | 69.398 | rs11591147 | 0.318746 | phospholipids in large LDL measurement (EFO:0022174) |
PMID:36764567 |
GWAS692627_H | GCST90302110 | Total lipids in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-26 | 25.523 | rs11591147 | 0.1542 | total lipids in small VLDL (EFO:0022148) |
PMID:38448586 |
GWAS692656_H | GCST90302109 | Free cholesterol to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 1E-9 | 9 | rs11591147 | 0.0887 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS694257_H | GCST90302113 | Phospholipids to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 8E-36 | 35.097 | rs11591147 | 0.1784 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS694540_H | GCST90302108 | Free cholesterol in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 9E-30 | 29.046 | rs11591147 | 0.1649 | free cholesterol in small VLDL measurement (EFO:0022272) |
PMID:38448586 |
None Available | GCST90302115 | Triglycerides to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 5E-67 | 66.302 | rs11591147 | 0.2472 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS701940_H | GCST90302124 | Mean diameter of VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 2E-11 | 10.699 | rs11591147 | 0.0961 | very low density lipoprotein particle size measurement (EFO:0008594) |
PMID:38448586 |
GWAS702475_H | GCST90302168 | Total lipid levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-13 | 12.302 | rs11591147 | 0.1055 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:38448586 |
GWAS702840_H | GCST90302156 | Total lipids in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-134 | 133.699 | rs11591147 | 0.3591 | total lipids in very small VLDL measurement (EFO:0022156) |
PMID:38448586 |
GWAS703336_H | GCST90302158 | Phospholipids in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-179 | 178.699 | rs11591147 | 0.416 | phospholipids in VLDL measurement (EFO:0022301) |
PMID:38448586 |
GWAS703908_H | GCST90302165 | Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0292 | 1E-41 | 41 | rs11591147 | 0.2128 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
None Available | GCST90302126 | Total cholesterol levels in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-17 | 16.523 | rs11591147 | 0.1228 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS705086_H | GCST90302170 | Phospholipid levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 6E-10 | 9.222 | rs11591147 | 0.0903 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:38448586 |
GWAS705254_H | GCST90302159 | Phospholipids to total lipids ratio in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 2E-85 | 84.699 | rs11591147 | 0.285 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS705598_H | GCST90302123 | Total cholesterol levels in VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 7E-62 | 61.155 | rs11591147 | 0.2415 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS705942_H | GCST90301957 | Esterified cholesterol levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 8E-159 | 158.097 | rs11591147 | 0.3918 | esterified cholesterol measurement (EFO:0008589) |
PMID:38448586 |
GWAS706335_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 8E-12 | 11.097 | rs11591147 | 0.081472576 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS706414_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 2E-7 | 6.699 | rs11591147 | 0.07703123 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS707486_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 7E-14 | 13.155 | rs11591147 | 0.11047237 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS707488_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 1E-13 | 13 | rs11591147 | 0.10913579 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 2E-13 | 12.699 | rs11591147 | 0.1093784 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 4E-10 | 9.398 | rs11591147 | 0.09261733 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 4E-10 | 9.398 | rs11591147 | 0.091919355 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS707777_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 7E-10 | 9.155 | rs11591147 | 0.09137215 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 2E-13 | 12.699 | rs11591147 | 0.10846748 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS707827_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 7E-13 | 12.155 | rs11591147 | 0.08888055 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS708877_H | GCST010337 | Low density lipoprotein cholesterol levels (on statin treatment) | 28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals | T | 0.011 | 8E-10 | 9.097 | rs11591147 | 0.073 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:31969989 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 8E-10 | 9.097 | rs11591147 | 0.09094943 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 1E-9 | 9 | rs11591147 | 0.08981017 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST90302169 | Concentration of chylomicrons and extremely large VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-13 | 12.699 | rs11591147 | 0.1071 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS710017_H | GCST001408 | Response to statins (LDL cholesterol change) | 6,989 European ancestry individuals | ? | NR | 5E-9 | 8.302 | rs11591147 | 5.0 | response to statin (GO:0036273) LDL cholesterol change measurement (EFO:0007804) |
PMID:22331829 |
None Available | GCST90301955 | Docosahexaenoic acid (22:6) levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-18 | 17.699 | rs11591147 | 0.1278 | docosahexaenoic acid measurement (EFO:0007761) |
PMID:38448586 |
None Available | GCST90301958 | Estimated description of fatty acid chain length not actual carbon number | 74,743 Non-Finnish European ancestry individuals | T | 0.0172 | 1E-19 | 19 | rs11591147 | 0.2019 | fatty acid change measurement (EFO:0020875) |
PMID:38448586 |
None Available | GCST010241 | Apolipoprotein A1 levels | 393,193 European ancestry individuals | G | 0.982588 | 1E-12 | 12 | rs11591147 | 0.0532417 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:32203549 |
GWAS710364_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000003 | 5.523 | rs11591147 | 0.06926624 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000003 | 5.523 | rs11591147 | 0.06899652 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000003 | 5.523 | rs11591147 | 0.06904491 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS710367_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 0.000004 | 5.398 | rs11591147 | 0.06872299 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
GWAS710696_H | GCST009242 | Serum metabolite levels | 6,263 Finnish ancestry men | ? | NR | 7E-7 | 6.155 | rs11591147 | 0.0735147 | serum metabolite measurement (EFO:0005653) |
PMID:31636271 |
None Available | GCST90301970 | Total cholesterol in HDL3 | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 2E-18 | 17.699 | rs11591147 | 0.1271 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90000616 | Serum 25-Hydroxyvitamin D levels | 417,580 European ancestry individuals | G | 0.981959 | 4E-10 | 9.398 | rs11591147 | 0.046 | vitamin D measurement (EFO:0004631) |
PMID:32242144 |
None Available | GCST90245341 | N-palmitoyl-sphingosine (d18:1/16:0) levels | 14,296 European ancestry individuals | T | 0.018 | 1E-8 | 8 | rs11591147 | 0.21982628 | N-palmitoyl-sphingosine (d18:1/16:0) measurement (EFO:0800607) |
PMID:36357675 |
None Available | GCST90302160 | Triglycerides in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-17 | 17 | rs11591147 | 0.1243 | triglycerides in very small VLDL measurement (EFO:0022144) |
PMID:38448586 |
GWAS715875_H | GCST005194 | Coronary artery disease | 34,541 cases, 261,984 controls | T | 0.016 | 2E-25 | 24.699 | rs11591147 | 0.282 | coronary artery disease (EFO:0001645) |
PMID:29212778 |
GWAS716121_H | GCST90302162 | Total cholesterol levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-19 | 18.523 | rs11591147 | 0.1306 | chylomicron measurement (EFO:0008596) total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS716376_H | GCST90302161 | Triglycerides to total lipids ratio in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0285 | 3E-53 | 52.523 | rs11591147 | 0.219 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS716403_H | GCST90302173 | Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0286 | 7E-19 | 18.155 | rs11591147 | 0.1369 | chylomicron measurement (EFO:0008596) triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS716926_H | GCST90301975 | Total Cholesterol in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-220 | 219.699 | rs11591147 | 0.4612 | total cholesterol in IDL (EFO:0022184) |
PMID:38448586 |
GWAS717594_H | GCST90302172 | Triglyceride levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-12 | 11.302 | rs11591147 | 0.1004 | chylomicron measurement (EFO:0008596) triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS717670_H | GCST90302164 | Cholesteryl ester levels in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-31 | 30.699 | rs11591147 | 0.1697 | cholesteryl ester measurement (EFO:0010351) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS718879_H | GCST90302163 | Total cholesterol to total lipids ratio in chylomicrons and extremely large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0285 | 6E-23 | 22.222 | rs11591147 | 0.1498 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:38448586 |
GWAS719478_H | GCST90301947 | Ratio of apolipoprotein B to apolipoprotein A1 levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-91 | 91 | rs11591147 | 0.2952 | apolipoprotein A 1 measurement (EFO:0004614) apolipoprotein B measurement (EFO:0004615) |
PMID:38448586 |
None Available | GCST90301945 | Apolipoprotein A-I levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 1E-10 | 10 | rs11591147 | 0.094 | apolipoprotein A 1 measurement (EFO:0004614) |
PMID:38448586 |
GWAS720856_H | GCST008079 | LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) | 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers | T | NR | 2E-175 | 174.699 | rs11591147 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) alcohol drinking (EFO:0004329) |
PMID:30698716 |
GWAS721703_H | GCST90301946 | Apolipoprotein B levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-142 | 141.302 | rs11591147 | 0.3693 | apolipoprotein B measurement (EFO:0004615) |
PMID:38448586 |
GWAS722726_H | GCST90301959 | Omega-3 fatty acids levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 5E-31 | 30.302 | rs11591147 | 0.1698 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:38448586 |
GWAS722825_H | GCST90244372 | Sterol ester (27:1/16:0) levels | 4,642 European ancestry women | T | NR | 6E-9 | 8.222 | rs11591147 | 0.3512 | PMID:36193934 | |
GWAS723131_H | GCST90270119 | Multi-trait sum score | 141,980 European ancestry males | ? | NR | 5E-10 | 9.302 | rs11591147 | N/A | complex trait (EFO:0010578) |
PMID:37277458 |
GWAS723290_H | GCST90269681 | Phospholipids to total lipids in very large VLDL percentage (UKB data field 23584) | 87,620 European ancestry individuals | T | 0.0172506 | 7E-37 | 36.155 | rs11591147 | 0.229637 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS723856_H | GCST90269678 | Cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23581) | 85,701 European ancestry individuals | T | 0.0172693 | 6E-14 | 13.222 | rs11591147 | 0.137351 | cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (EFO:0022246) |
PMID:36764567 |
None Available | GCST90244330 | Sphingomyelin (d40:2) levels | 2,624 European ancestry men | T | NR | 0.000001 | 6 | rs11591147 | 0.3934 | PMID:36193934 | |
GWAS724386_H | GCST90301977 | Cholesterol esters in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 6E-214 | 213.222 | rs11591147 | 0.4543 | esterified cholesterol measurement (EFO:0008589) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
None Available | GCST90245276 | Lactosyl-N-palmitoyl-sphingosine levels | 14,296 European ancestry individuals | T | 0.018 | 2E-13 | 12.699 | rs11591147 | 0.28556582 | metabolite measurement (EFO:0004725) |
PMID:36357675 |
None Available | GCST90301962 | Ratio of omega-6 fatty acids to total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0298 | 2E-10 | 9.699 | rs11591147 | 0.0956 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
GWAS725157_H | GCST90244323 | Sphingomyelin (d34:1) levels | 2,624 European ancestry men | T | NR | 7E-11 | 10.155 | rs11591147 | 0.523323 | PMID:36193934 | |
GWAS725269_H | GCST90301963 | Free cholesterol levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 6E-183 | 182.222 | rs11591147 | 0.4208 | free cholesterol measurement (EFO:0008591) |
PMID:38448586 |
GWAS725310_H | GCST90301978 | Cholesteryl esters to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.029 | 1E-31 | 31 | rs11591147 | 0.1696 | cholesteryl esters:total lipids ratio (EFO:0020944) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS725391_H | GCST90269682 | Cholesterol to total lipids in very large VLDL percentage (UKB data field 23585) | 87,620 European ancestry individuals | T | 0.0172506 | 6E-35 | 34.222 | rs11591147 | 0.215307 | cholesterol to total lipids in very large VLDL percentage (EFO:0022244) |
PMID:36764567 |
None Available | GCST90244327 | Sphingomyelin (d38:1) levels | 2,624 European ancestry men | T | NR | 1E-8 | 8 | rs11591147 | 0.4577 | PMID:36193934 | |
GWAS726152_H | GCST90301961 | Omega-6 fatty acids levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 7E-87 | 86.155 | rs11591147 | 0.2883 | omega-6 polyunsaturated fatty acid measurement (EFO:0005680) |
PMID:38448586 |
None Available | GCST90244502 | Sphingomyelin (d34:1) levels | 4,642 European ancestry women | T | NR | 1E-9 | 9 | rs11591147 | 0.3681 | PMID:36193934 | |
GWAS726903_H | GCST90269700 | Triglycerides to total lipids in small VLDL percentage (UKB data field 23603) | 88,329 European ancestry individuals | T | 0.0173273 | 9E-68 | 67.046 | rs11591147 | 0.306218 | triglycerides to total lipids in small VLDL percentage (EFO:0022338) |
PMID:36764567 |
GWAS727046_H | GCST90269710 | Triglycerides to total lipids in IDL percentage (UKB data field 23613) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-34 | 33.398 | rs11591147 | 0.213387 | triglycerides to total lipids in IDL percentage (EFO:0022329) |
PMID:36764567 |
None Available | GCST004787 | Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) | 18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls | G | 0.984 | 3E-10 | 9.523 | rs11591147 | 1.25 | coronary artery disease (EFO:0001645) |
PMID:28714975 |
GWAS728236_H | GCST90269697 | Cholesterol to total lipids in small VLDL percentage (UKB data field 23600) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-69 | 68.523 | rs11591147 | 0.311596 | cholesterol to total lipids in small VLDL percentage (EFO:0022242) |
PMID:36764567 |
GWAS728656_H | GCST90302049 | Total lipid levels in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-192 | 192 | rs11591147 | 0.4311 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:38448586 |
None Available | GCST90302022 | Cholesteryl esters to total lipids ratio in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0282 | 2E-18 | 17.699 | rs11591147 | 0.1358 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS728851_H | GCST90269698 | Cholesteryl esters to total lipids in small VLDL percentage (UKB data field 23601) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-64 | 64 | rs11591147 | 0.304631 | cholesteryl esters to total lipids in small VLDL percentage (EFO:0022256) |
PMID:36764567 |
None Available | GCST90302024 | Free cholesterol to total lipids ratio in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0286 | 3E-10 | 9.523 | rs11591147 | 0.102 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
None Available | GCST90244860 | 1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) levels | 14,296 European ancestry individuals | T | 0.0181 | 2E-10 | 9.699 | rs11591147 | 0.2506767 | 1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement (EFO:0800466) |
PMID:36357675 |
GWAS729745_H | GCST90245359 | Palmitoyl dihydrosphingomyelin (d18:0/16:0) levels | 14,296 European ancestry individuals | T | 0.018 | 2E-24 | 23.699 | rs11591147 | 0.38922724 | palmitoyl dihydrosphingomyelin (d18:0/16:0) measurement (EFO:0800400) |
PMID:36357675 |
None Available | GCST90302006 | Triglycerides to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 4E-11 | 10.398 | rs11591147 | 0.0974 | triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS729987_H | GCST90245361 | Palmitoyl sphingomyelin (d18:1/16:0) levels | 14,296 European ancestry individuals | T | 0.018 | 7E-24 | 23.155 | rs11591147 | 0.3851659 | palmitoyl sphingomyelin (d18:1/16:0) measurement (EFO:0800300) |
PMID:36357675 |
None Available | GCST90269699 | Free cholesterol to total lipids in small VLDL percentage (UKB data field 23602) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-57 | 56.699 | rs11591147 | 0.277093 | free cholesterol to total lipids in small VLDL percentage (EFO:0022287) |
PMID:36764567 |
GWAS730304_H | GCST90301979 | Free cholesterol in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-222 | 221.302 | rs11591147 | 0.4631 | free cholesterol in IDL measurement (EFO:0022181) |
PMID:38448586 |
GWAS731141_H | GCST90301980 | Free cholesterol to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.029 | 1E-62 | 62 | rs11591147 | 0.2422 | free cholesterol:total lipids ratio (EFO:0020945) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS731615_H | GCST90302032 | Total cholesterol to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0285 | 3E-14 | 13.523 | rs11591147 | 0.1086 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS731951_H | GCST90301996 | Total cholesterol to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.028 | 3E-15 | 14.523 | rs11591147 | 0.1138 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90269708 | Cholesteryl esters to total lipids in IDL percentage (UKB data field 23611) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-17 | 17 | rs11591147 | 0.150814 | cholesteryl esters to total lipids in IDL percentage (EFO:0022247) |
PMID:36764567 |
GWAS732184_H | GCST008077 | LDL cholesterol levels | 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals | T | NR | 9E-50 | 49.046 | rs11591147 | 16.1 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30698716 |
None Available | GCST005196 | Coronary artery disease | 88,192 cases, 162,544 controls | T | 0.0163 | 2E-25 | 24.699 | rs11591147 | 0.2821 | coronary artery disease (EFO:0001645) |
PMID:29212778 |
GWAS732558_H | GCST90302008 | Total cholesterol to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 6E-171 | 170.222 | rs11591147 | 0.4051 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS732786_H | GCST90269731 | Phospholipids to total lipids in large HDL percentage (UKB data field 23634) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-37 | 37 | rs11591147 | 0.225561 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS732849_H | GCST005574 | Osteoarthritis of the knee (with total joint replacement) | 2,188 European ancestry cases, 9,939 European ancestry healthy controls | T | 0.017137 | 0.000009 | 5.046 | rs11591147 | 1.56 | osteoarthritis, knee (EFO:0004616) |
PMID:29436472 |
GWAS733737_H | GCST90301984 | Phospholipids to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 1E-28 | 28 | rs11591147 | 0.1577 | phospholipids:total lipids ratio (EFO:0020946) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS733799_H | GCST90302033 | Cholesterol esters in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0279 | 9E-12 | 11.046 | rs11591147 | 0.0988 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90269717 | Cholesterol to total lipids in medium LDL percentage (UKB data field 23620) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-15 | 14.523 | rs11591147 | 0.14305 | cholesterol to total lipids in medium LDL percentage (EFO:0022238) |
PMID:36764567 |
GWAS734999_H | GCST90302009 | Cholesterol esters in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-213 | 212.699 | rs11591147 | 0.4539 | cholesterol esters in large LDL measurement (EFO:0022165) |
PMID:38448586 |
GWAS735153_H | GCST90302050 | Concentration of medium LDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-190 | 189.699 | rs11591147 | 0.4285 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS735350_H | GCST008077 | LDL cholesterol levels | 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals | T | NR | 7E-52 | 51.155 | rs11591147 | 16.48 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30698716 |
GWAS735464_H | GCST90302051 | Phospholipids in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-167 | 166.699 | rs11591147 | 0.4015 | phospholipids in medium LDL measurement (EFO:0022183) |
PMID:38448586 |
GWAS735508_H | GCST90302007 | Total cholesterol in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-217 | 216.302 | rs11591147 | 0.4577 | total cholesterol in large LDL (EFO:0022167) |
PMID:38448586 |
None Available | GCST90301986 | Triglycerides to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 7E-52 | 51.155 | rs11591147 | 0.2151 | triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS735876_H | GCST90269707 | Cholesterol to total lipids in IDL percentage (UKB data field 23610) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-26 | 25.398 | rs11591147 | 0.186996 | cholesterol to total lipids in IDL percentage (EFO:0022233) |
PMID:36764567 |
GWAS736070_H | GCST90301998 | Cholesteryl esters to total lipids ratio in large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0281 | 7E-33 | 32.155 | rs11591147 | 0.1723 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS736136_H | GCST90302040 | Phospholipids to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0287 | 8E-13 | 12.097 | rs11591147 | 0.1032 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS736155_H | GCST90301985 | Triglycerides in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 4E-47 | 46.398 | rs11591147 | 0.21 | triglycerides in IDL measurement (EFO:0022149) |
PMID:38448586 |
GWAS736223_H | GCST90301988 | Linoleic acid (18:2) levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 6E-83 | 82.222 | rs11591147 | 0.2816 | linoleic acid measurement (EFO:0006807) |
PMID:38448586 |
GWAS736353_H | GCST90245418 | Sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0) levels | 14,296 European ancestry individuals | T | 0.018 | 7E-12 | 11.155 | rs11591147 | 0.26729846 | Sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0) measurement (EFO:0022107) |
PMID:36357675 |
None Available | GCST90245426 | Sphingomyelin (d18:2/16:0, d18:1/16:1) levels | 14,296 European ancestry individuals | T | 0.0179 | 5E-12 | 11.302 | rs11591147 | 0.26419416 | Sphingomyelin (d18:2/16:0, d18:1/16:1) measurement (EFO:0022115) |
PMID:36357675 |
GWAS736530_H | GCST90302030 | Triglycerides to total lipids ratio in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0276 | 2E-54 | 53.699 | rs11591147 | 0.2353 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS736542_H | GCST90301991 | Total cholesterol levels in LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 7E-210 | 209.155 | rs11591147 | 0.4505 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS737137_H | GCST90269694 | Free cholesterol to total lipids in medium VLDL percentage (UKB data field 23597) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-62 | 61.523 | rs11591147 | 0.288765 | free cholesterol to total lipids in medium VLDL percentage (EFO:0022284) |
PMID:36764567 |
None Available | GCST90301989 | Ratio of 18:2 linoleic acid to total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 2E-10 | 9.699 | rs11591147 | 0.0927 | fatty acid measurement (EFO:0005110) linoleic acid measurement (EFO:0006807) |
PMID:38448586 |
GWAS737580_H | GCST90302020 | Total cholesterol to total lipids ratio in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0281 | 9E-29 | 28.046 | rs11591147 | 0.1727 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:38448586 |
None Available | GCST90245417 | Sphingomyelin (d18:1/15:0, d16:1/17:0) levels | 14,296 European ancestry individuals | T | 0.018 | 4E-11 | 10.398 | rs11591147 | 0.25238475 | Sphingomyelin (d18:1/15:0, d16:1/17:0) measurement (EFO:0022106) |
PMID:36357675 |
GWAS738397_H | GCST90269696 | Phospholipids to total lipids in small VLDL percentage (UKB data field 23599) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-57 | 56.523 | rs11591147 | 0.277316 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
GWAS739073_H | GCST90302028 | Phospholipids to total lipids ratio in large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0296 | 1E-56 | 56 | rs11591147 | 0.252 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
None Available | GCST90269695 | Triglycerides to total lipids in medium VLDL percentage (UKB data field 23598) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-56 | 56 | rs11591147 | 0.27303 | triglycerides to total lipids in medium VLDL percentage (EFO:0022335) |
PMID:36764567 |
GWAS739534_H | GCST90302034 | Cholesteryl esters to total lipids ratio in medium HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 5E-23 | 22.302 | rs11591147 | 0.1413 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS739682_H | GCST005195 | Coronary artery disease | up to 122,733 cases, up to 424,528 controls | T | 0.0164 | 2E-22 | 21.699 | rs11591147 | 0.2406 | coronary artery disease (EFO:0001645) |
PMID:29212778 |
GWAS739852_H | GCST90301993 | Triglyceride levels in LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-55 | 54.523 | rs11591147 | 0.2283 | triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS739915_H | GCST90301981 | Total lipids in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-214 | 213.523 | rs11591147 | 0.4547 | total lipids in IDL (EFO:0022161) |
PMID:38448586 |
None Available | GCST90245416 | Sphingomyelin (d18:1/14:0, d16:1/16:0) levels | 14,296 European ancestry individuals | T | 0.018 | 7E-11 | 10.155 | rs11591147 | 0.2490525 | Sphingomyelin (d18:1/14:0, d16:1/16:0) measurement (EFO:0022105) |
PMID:36357675 |
GWAS740194_H | GCST90245434 | Stearoyl sphingomyelin (d18:1/18:0) levels | 14,296 European ancestry individuals | T | 0.018 | 2E-15 | 14.699 | rs11591147 | 0.30414513 | stearoyl sphingomyelin (d18:1/18:0) measurement (EFO:0800611) |
PMID:36357675 |
None Available | GCST90302012 | Free cholesterol to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 3E-23 | 22.523 | rs11591147 | 0.1411 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS740756_H | GCST90302010 | Cholesteryl esters to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.029 | 4E-173 | 172.398 | rs11591147 | 0.4076 | low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS741318_H | GCST008078 | LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) | 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers | T | NR | 4E-171 | 170.398 | rs11591147 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) alcohol consumption measurement (EFO:0007878) |
PMID:30698716 |
GWAS741639_H | GCST90269715 | Triglycerides to total lipids in large LDL percentage (UKB data field 23618) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-28 | 27.523 | rs11591147 | 0.194791 | triglycerides to total lipids in large LDL percentage (EFO:0022331) |
PMID:36764567 |
GWAS742890_H | GCST008078 | LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) | 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers | T | NR | 3E-176 | 175.523 | rs11591147 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) alcohol consumption measurement (EFO:0007878) |
PMID:30698716 |
GWAS743469_H | GCST008079 | LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) | 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers | T | NR | 6E-169 | 168.222 | rs11591147 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) alcohol drinking (EFO:0004329) |
PMID:30698716 |
GWAS743473_H | GCST90302011 | Free cholesterol in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-220 | 219.302 | rs11591147 | 0.4612 | free cholesterol in large LDL measurement (EFO:0022176) |
PMID:38448586 |
GWAS743537_H | GCST90269734 | Free cholesterol to total lipids in large HDL percentage (UKB data field 23637) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-39 | 38.523 | rs11591147 | 0.222064 | free cholesterol to total lipids in large HDL percentage (EFO:0022279) |
PMID:36764567 |
GWAS744571_H | GCST90302048 | Free cholesterol to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0283 | 2E-168 | 167.699 | rs11591147 | 0.394 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS744645_H | GCST90302047 | Free cholesterol in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-184 | 183.523 | rs11591147 | 0.4216 | free cholesterol in medium LDL measurement (EFO:0022268) |
PMID:38448586 |
GWAS744861_H | GCST90302045 | Cholesterol esters in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-201 | 201 | rs11591147 | 0.4411 | cholesterol esters in medium LDL measurement (EFO:0022186) |
PMID:38448586 |
GWAS745053_H | GCST90302046 | Cholesteryl esters to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 1E-173 | 173 | rs11591147 | 0.4084 | low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS745498_H | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.987 | 5E-56 | 55.302 | rs11591147 | 0.413 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
None Available | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | 0.989 | 9E-11 | 10.046 | rs11591147 | 0.464 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
None Available | GCST007143 | Total cholesterol levels | 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals | G | NR | 5E-11 | 10.302 | rs11591147 | 0.458 | total cholesterol measurement (EFO:0004574) |
PMID:29507422 |
GWAS745542_H | GCST90269744 | Free cholesterol to total lipids in small HDL percentage (UKB data field 23647) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-48 | 48 | rs11591147 | 0.253721 | free cholesterol to total lipids in small HDL percentage (EFO:0022285) |
PMID:36764567 |
None Available | GCST90269688 | Cholesteryl esters to total lipids in large VLDL percentage (UKB data field 23591) | 88,321 European ancestry individuals | T | 0.0173288 | 1E-41 | 41 | rs11591147 | 0.235396 | cholesteryl esters to total lipids in large VLDL percentage (EFO:0022250) |
PMID:36764567 |
None Available | GCST90269689 | Free cholesterol to total lipids in large VLDL percentage (UKB data field 23592) | 88,321 European ancestry individuals | T | 0.0173288 | 2E-22 | 21.699 | rs11591147 | 0.175084 | free cholesterol to total lipids in large VLDL percentage (EFO:0022281) |
PMID:36764567 |
GWAS746208_H | GCST90269691 | Phospholipids to total lipids in medium VLDL percentage (UKB data field 23594) | 88,329 European ancestry individuals | T | 0.0173273 | 6E-74 | 73.222 | rs11591147 | 0.317532 | phospholipids:total lipids ratio (EFO:0020946) |
PMID:36764567 |
None Available | GCST90269693 | Cholesteryl esters to total lipids in medium VLDL percentage (UKB data field 23596) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-45 | 44.699 | rs11591147 | 0.242052 | cholesteryl esters to total lipids in medium VLDL percentage (EFO:0022253) |
PMID:36764567 |
GWAS746927_H | GCST90269690 | Triglycerides to total lipids in large VLDL percentage (UKB data field 23593) | 88,321 European ancestry individuals | T | 0.0173288 | 1E-35 | 35 | rs11591147 | 0.224665 | triglycerides to total lipids in large VLDL percentage (EFO:0022332) |
PMID:36764567 |
None Available | GCST90269692 | Cholesterol to total lipids in medium VLDL percentage (UKB data field 23595) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-50 | 49.699 | rs11591147 | 0.256524 | cholesterol to total lipids in medium VLDL percentage (EFO:0022239) |
PMID:36764567 |
GWAS747199_H | GCST90269703 | Cholesteryl esters to total lipids in very small VLDL percentage (UKB data field 23606) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-39 | 38.699 | rs11591147 | 0.225456 | cholesteryl esters to total lipids in very small VLDL percentage (EFO:0022259) |
PMID:36764567 |
None Available | GCST90269702 | Cholesterol to total lipids in very small VLDL percentage (UKB data field 23605) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-44 | 43.302 | rs11591147 | 0.239978 | cholesterol to total lipids in very small VLDL percentage (EFO:0022245) |
PMID:36764567 |
GWAS747898_H | GCST90269722 | Cholesterol to total lipids in small LDL percentage (UKB data field 23625) | 88,329 European ancestry individuals | T | 0.0173273 | 5E-19 | 18.302 | rs11591147 | 0.161655 | cholesterol to total lipids in small LDL percentage (EFO:0022241) |
PMID:36764567 |
GWAS749015_H | GCST90269712 | Cholesterol to total lipids in large LDL percentage (UKB data field 23615) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-28 | 27.398 | rs11591147 | 0.193519 | cholesterol to total lipids in large LDL percentage (EFO:0022235) |
PMID:36764567 |
GWAS751710_H | GCST90269720 | Triglycerides to total lipids in medium LDL percentage (UKB data field 23623) | 88,329 European ancestry individuals | T | 0.0173273 | 3E-31 | 30.523 | rs11591147 | 0.206986 | triglycerides to total lipids in medium LDL percentage (EFO:0022334) |
PMID:36764567 |
GWAS752898_H | GCST007072 | Cardiovascular disease | approximately 459,000 European ancestry individuals | ? | NR | 1E-11 | 11 | rs11591147 | N/A | cardiovascular disease (EFO:0000319) |
PMID:30595370 |
GWAS754364_H | GCST90302013 | Total lipids in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 6E-210 | 209.222 | rs11591147 | 0.4501 | total lipids in large LDL (EFO:0022163) |
PMID:38448586 |
GWAS755087_H | GCST90302014 | Concentration of large LDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-205 | 205 | rs11591147 | 0.4454 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
None Available | GCST90309350 | Coronary artery disease (confirmatory factor analysis Factor 16) | 360,021 European ancestry individuals | ? | NR | 4E-17 | 16.398 | rs11591147 | N/A | coronary artery disease (EFO:0001645) |
PMID:38965376 |
GWAS758851_H | GCST90269510 | Phospholipids in LDL (UKB data field 23413) | 88,329 European ancestry individuals | T | 0.0173273 | 8E-69 | 68.097 | rs11591147 | 0.317157 | phospholipids in LDL measurement (EFO:0022294) |
PMID:36764567 |
None Available | GCST90302018 | Triglycerides to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 1E-42 | 42 | rs11591147 | 0.1941 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
None Available | GCST90269538 | Apolipoprotein B to apolipoprotein A1 ratio (UKB data field 23441) | 88,329 European ancestry individuals | T | 0.0173273 | 1E-61 | 61 | rs11591147 | 0.296127 | apolipoprotein B to apolipoprotein A1 ratio (EFO:0021897) |
PMID:36764567 |
GWAS761315_H | GCST90302017 | Triglycerides in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-60 | 60 | rs11591147 | 0.2393 | triglycerides in large LDL measurement (EFO:0022319) |
PMID:38448586 |
GWAS762030_H | GCST90269536 | Apolipoprotein B levels (UKB data field 23439) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-71 | 70.398 | rs11591147 | 0.322643 | apolipoprotein B measurement (EFO:0004615) |
PMID:36764567 |
GWAS764491_H | GCST90269625 | Free cholesterol in IDL (UKB data field 23528) | 88,329 European ancestry individuals | T | 0.0173273 | 6E-80 | 79.222 | rs11591147 | 0.332848 | free cholesterol in IDL measurement (EFO:0022181) |
PMID:36764567 |
GWAS764672_H | GCST90269624 | Cholesteryl esters in IDL (UKB data field 23527) | 88,329 European ancestry individuals | T | 0.0173273 | 4E-76 | 75.398 | rs11591147 | 0.323545 | cholesteryl ester measurement (EFO:0010351) |
PMID:36764567 |
None Available | GCST90269623 | Cholesterol in IDL (UKB data field 23526) | 88,329 European ancestry individuals | T | 0.0173273 | 6E-78 | 77.222 | rs11591147 | 0.32773 | cholesterol in IDL measurement (EFO:0021899) |
PMID:36764567 |
GWAS767789_H | GCST90301982 | Concentration of IDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 6E-208 | 207.222 | rs11591147 | 0.4479 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
GWAS767870_H | GCST90302016 | Phospholipids to total lipids ratio in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0285 | 8E-201 | 200.097 | rs11591147 | 0.4307 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS768709_H | GCST90301983 | Phospholipids in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-218 | 218 | rs11591147 | 0.4593 | phospholipids in IDL measurement (EFO:0022164) |
PMID:38448586 |
GWAS769290_H | GCST90269622 | Phospholipids in IDL (UKB data field 23525) | 88,329 European ancestry individuals | T | 0.0173273 | 2E-81 | 80.699 | rs11591147 | 0.334667 | phospholipids in IDL measurement (EFO:0022164) |
PMID:36764567 |
GWAS769365_H | GCST90302081 | Cholesterol esters in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 4E-33 | 32.398 | rs11591147 | 0.1744 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS769590_H | GCST90302075 | Serum total cholesterol levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-171 | 170.699 | rs11591147 | 0.4064 | total cholesterol measurement (EFO:0004574) |
PMID:38448586 |
GWAS769692_H | GCST90302084 | Free cholesterol to total lipids ratio in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0283 | 2E-72 | 71.699 | rs11591147 | 0.2555 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS769725_H | GCST90302094 | Cholesteryl esters to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 2E-187 | 186.699 | rs11591147 | 0.4244 | cholesterol:total lipids ratio (EFO:0020943) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS769845_H | GCST90302069 | Phosphatidylcholine and other choline levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-46 | 45.699 | rs11591147 | 0.209 | choline measurement (EFO:0010116) |
PMID:38448586 |
GWAS769857_H | GCST90302071 | Polyunsaturated fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-83 | 82.699 | rs11591147 | 0.2823 | polyunsaturated fatty acid measurement (EFO:0010733) |
PMID:38448586 |
None Available | GCST90302072 | Ratio of polyunsaturated fatty acids to total fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 4E-10 | 9.398 | rs11591147 | 0.0912 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
None Available | GCST90302080 | Total cholesterol to total lipids ratio in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.029 | 2E-81 | 80.699 | rs11591147 | 0.2773 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS770116_H | GCST90302044 | Total cholesterol to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 2E-153 | 152.699 | rs11591147 | 0.3832 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS770386_H | GCST90302066 | Phospholipids to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0287 | 2E-20 | 19.699 | rs11591147 | 0.1337 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
None Available | GCST90302097 | Total lipids in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 3E-184 | 183.523 | rs11591147 | 0.4214 | total lipids in small LDL (EFO:0022168) |
PMID:38448586 |
None Available | GCST90302083 | Free cholesterol in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 1E-32 | 32 | rs11591147 | 0.1696 | free cholesterol in small HDL measurement (EFO:0022270) |
PMID:38448586 |
GWAS770868_H | GCST90302087 | Phospholipids in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0286 | 3E-49 | 48.523 | rs11591147 | 0.2104 | phospholipids in small HDL measurement (EFO:0022296) |
PMID:38448586 |
GWAS771061_H | GCST90302077 | Saturated fatty acids | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 4E-39 | 38.398 | rs11591147 | 0.1913 | saturated fatty acids measurement (EFO:0022304) |
PMID:38448586 |
GWAS771080_H | GCST90302082 | Cholesteryl esters to total lipids ratio in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 1E-88 | 88 | rs11591147 | 0.2896 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS771332_H | GCST90302074 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-136 | 136 | rs11591147 | 0.362 | remnant cholesterol measurement (EFO:0010815) |
PMID:38448586 |
GWAS771578_H | GCST90302043 | Total cholesterol in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-200 | 199.699 | rs11591147 | 0.4399 | total cholesterol in medium LDL (EFO:0022185) |
PMID:38448586 |
GWAS771695_H | GCST90302088 | Phospholipids to total lipids ratio in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 5E-112 | 111.302 | rs11591147 | 0.3197 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS771974_H | GCST90302079 | Total cholesterol levels in small HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 3E-27 | 26.523 | rs11591147 | 0.1572 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS772667_H | GCST90302096 | Free cholesterol to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0273 | 5E-172 | 171.302 | rs11591147 | 0.4083 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS773443_H | GCST90302015 | Phospholipids in large LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 9E-205 | 204.046 | rs11591147 | 0.4444 | phospholipids in large LDL measurement (EFO:0022174) |
PMID:38448586 |
GWAS773866_H | GCST90302068 | Triglycerides to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0283 | 9E-78 | 77.046 | rs11591147 | 0.2661 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
GWAS774582_H | GCST90302057 | Total cholesterol in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 4E-24 | 23.398 | rs11591147 | 0.1475 | total cholesterol in medium VLDL (EFO:0022162) |
PMID:38448586 |
GWAS775095_H | GCST90302095 | Free cholesterol in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 8E-161 | 160.097 | rs11591147 | 0.3937 | free cholesterol in small LDL measurement (EFO:0022271) |
PMID:38448586 |
GWAS775574_H | GCST90302103 | Sphingomyelins levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0299 | 3E-96 | 95.523 | rs11591147 | 0.3146 | sphingomyelin measurement (EFO:0010118) |
PMID:38448586 |
GWAS775844_H | GCST90302098 | Concentration of small LDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 5E-179 | 178.302 | rs11591147 | 0.4156 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS775851_H | GCST90302099 | Phospholipids in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 1E-135 | 135 | rs11591147 | 0.3609 | phospholipids in small LDL measurement (EFO:0022297) |
PMID:38448586 |
GWAS775861_H | GCST90302100 | Phospholipids to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0283 | 1E-199 | 199 | rs11591147 | 0.4292 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
GWAS776162_H | GCST90302091 | Total Cholesterol in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 6E-199 | 198.222 | rs11591147 | 0.4382 | total cholesterol in small LDL (EFO:0022179) |
PMID:38448586 |
GWAS776765_H | GCST90302093 | Cholesterol esters in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-203 | 202.699 | rs11591147 | 0.443 | esterified cholesterol measurement (EFO:0008589) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
None Available | GCST90302101 | Triglycerides in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 2E-44 | 43.699 | rs11591147 | 0.2038 | triglycerides in small LDL measurement (EFO:0022323) |
PMID:38448586 |
GWAS778041_H | GCST90302092 | Total cholesterol to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 6E-173 | 172.222 | rs11591147 | 0.4073 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS778208_H | GCST90270117 | Multi-trait sum score | 161,906 European ancestry females | ? | NR | 4E-8 | 7.398 | rs11591147 | N/A | complex trait (EFO:0010578) |
PMID:37277458 |
None Available | GCST90302133 | Concentration of very large HDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.029 | 2E-13 | 12.699 | rs11591147 | 0.1077 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90302130 | Free cholesterol in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 2E-16 | 15.699 | rs11591147 | 0.1195 | free cholesterol in very large HDL measurement (EFO:0022273) |
PMID:38448586 |
None Available | GCST90302128 | Cholesterol esters in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 5E-17 | 16.302 | rs11591147 | 0.1219 | esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
None Available | GCST90302132 | Total lipids in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.029 | 1E-13 | 13 | rs11591147 | 0.1086 | total lipids in very large HDL measurement (EFO:0022312) |
PMID:38448586 |
GWAS783923_H | GCST90302052 | Phospholipids to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0283 | 8E-183 | 182.097 | rs11591147 | 0.4101 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
None Available | GCST90302053 | Triglycerides in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-57 | 56.523 | rs11591147 | 0.2324 | triglycerides in medium LDL measurement (EFO:0022322) |
PMID:38448586 |
GWAS784482_H | GCST90302060 | Cholesteryl esters to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 5E-66 | 65.302 | rs11591147 | 0.2497 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
None Available | GCST90302131 | Free cholesterol to total lipids ratio in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0287 | 6E-11 | 10.222 | rs11591147 | 0.096 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:38448586 |
GWAS784669_H | GCST90302055 | Monounsaturated fatty acids (16:1, 18:1) levels | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-20 | 19.523 | rs11591147 | 0.1346 | fatty acid measurement (EFO:0005110) |
PMID:38448586 |
GWAS785492_H | GCST90302136 | Triglycerides in very large HDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 8E-29 | 28.097 | rs11591147 | 0.1624 | triglycerides in very large HDL measurement (EFO:0022324) |
PMID:38448586 |
GWAS786831_H | GCST90302058 | Total cholesterol to total lipids ratio in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0288 | 8E-75 | 74.097 | rs11591147 | 0.2661 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:38448586 |
None Available | GCST90302139 | Total cholesterol to total lipids ratio in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0296 | 2E-22 | 21.699 | rs11591147 | 0.1583 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:38448586 |
GWAS787449_H | GCST90302054 | Triglycerides to total lipids ratio in medium LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 4E-25 | 24.398 | rs11591147 | 0.1477 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS788296_H | GCST90302059 | Cholesterol esters in medium VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-43 | 43 | rs11591147 | 0.2016 | cholesterol esters in medium VLDL measurement (EFO:0022182) |
PMID:38448586 |
None Available | GCST90302141 | Cholesteryl esters to total lipids ratio in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0294 | 8E-10 | 9.097 | rs11591147 | 0.0994 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS790587_H | GCST90302106 | Cholesterol esters in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 1E-102 | 102 | rs11591147 | 0.3128 | very low density lipoprotein cholesterol measurement (EFO:0008317) esterified cholesterol measurement (EFO:0008589) |
PMID:38448586 |
GWAS790824_H | GCST90302105 | Total cholesterol to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 7E-90 | 89.155 | rs11591147 | 0.293 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:38448586 |
GWAS791133_H | GCST90302147 | Phospholipids to total lipids ratio in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0295 | 2E-41 | 40.699 | rs11591147 | 0.2188 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:38448586 |
None Available | GCST90302102 | Triglycerides to total lipids ratio in small LDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0284 | 4E-20 | 19.398 | rs11591147 | 0.131 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:38448586 |
GWAS792015_H | GCST90302107 | Cholesteryl esters to total lipids ratio in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 5E-90 | 89.302 | rs11591147 | 0.2932 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:38448586 |
GWAS792214_H | GCST90302104 | Total cholesterol in small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 7E-76 | 75.155 | rs11591147 | 0.2682 | total cholesterol in small VLDL (EFO:0022171) |
PMID:38448586 |
GWAS793233_H | GCST90302150 | Total cholesterol in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 2E-144 | 143.699 | rs11591147 | 0.3723 | cholesterol in very small VLDL measurement (EFO:0022231) |
PMID:38448586 |
GWAS793327_H | GCST90302143 | Free cholesterol to total lipids ratio in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0295 | 6E-25 | 24.222 | rs11591147 | 0.1667 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
None Available | GCST90302142 | Free cholesterol in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 1E-9 | 9 | rs11591147 | 0.0887 | free cholesterol in very large VLDL measurement (EFO:0022274) |
PMID:38448586 |
None Available | GCST90302149 | Triglycerides to total lipids ratio in very large VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals | T | 0.0289 | 2E-49 | 48.699 | rs11591147 | 0.2344 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90309362 | Diabetes (confirmatory factor analysis Factor 28) | 360,514 European ancestry individuals | ? | NR | 8E-11 | 10.097 | rs11591147 | N/A | diabetes mellitus (EFO:0000400) |
PMID:38965376 |
GWAS797398_H | GCST90302152 | Cholesterol esters in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 9E-139 | 138.046 | rs11591147 | 0.3649 | very low density lipoprotein cholesterol measurement (EFO:0008317) esterified cholesterol measurement (EFO:0008589) |
PMID:38448586 |
GWAS804365_H | GCST90302154 | Free cholesterol in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0291 | 3E-136 | 135.523 | rs11591147 | 0.3616 | free cholesterol in very small VLDL measurement (EFO:0022275) |
PMID:38448586 |
GWAS810108_H | GCST90302157 | Concentration of very small VLDL particles | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0292 | 3E-123 | 122.523 | rs11591147 | 0.3435 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:38448586 |
None Available | GCST90302155 | Free cholesterol to total lipids ratio in very small VLDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0288 | 3E-10 | 9.523 | rs11591147 | 0.0912 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:38448586 |
GWAS814434_H | GCST90092849 | Free cholesterol to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.982543 | 9E-49 | 48.046 | rs11591147 | 0.214652 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90010851 | Sphingomyeline C16:0 levels | 31,023 Caucasian ancestry individuals | G | 0.9827 | 2E-22 | 21.699 | rs11591147 | 9.761 | sphingomyelin measurement (EFO:0010118) |
PMID:33414548 |
GWAS817198_H | GCST90010853 | Sphingomyeline C18:0 levels | 31,120 Caucasian ancestry individuals | G | 0.9827 | 1E-14 | 14 | rs11591147 | 7.722 | sphingomyelin measurement (EFO:0010118) |
PMID:33414548 |
GWAS830174_H | GCST90092870 | Cholesteryl ester levels in large VLDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-29 | 28.398 | rs11591147 | 0.17375 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092868 | Cholesterol levels in large VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-17 | 16.699 | rs11591147 | 0.130846 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS831707_H | GCST90092869 | Cholesterol to total lipids ratio in large VLDL | 115,071 European ancestry individuals | G | 0.982546 | 8E-57 | 56.097 | rs11591147 | 0.244262 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
GWAS832075_H | GCST90018793 | Angina pectoris | 30,025 European ancestry cases, 440,906 European ancestry controls, 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls | T | NR | 6E-12 | 11.222 | rs11591147 | 0.2179 | angina pectoris (EFO:0003913) |
PMID:34594039 |
GWAS832335_H | GCST90092873 | Free cholesterol to total lipids ratio in large VLDL | 115,071 European ancestry individuals | G | 0.982546 | 3E-32 | 31.523 | rs11591147 | 0.184283 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
None Available | GCST90132314 | Coronary artery disease | 181,522 European ancestry, unknown cases, 984,168 European ancestry, unknown controls | T | 0.015 | 1E-28 | 28 | rs11591147 | 0.778 | coronary artery disease (EFO:0001645) |
PMID:36474045 |
None Available | GCST90092871 | Cholesteryl esters to total lipids ratio in large VLDL | 115,071 European ancestry individuals | G | 0.982546 | 9E-56 | 55.046 | rs11591147 | 0.236934 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS834419_H | GCST90092872 | Free cholesterol levels in large VLDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-9 | 8.155 | rs11591147 | 0.087951 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS834646_H | GCST90092863 | Concentration of large LDL particles | 115,082 European ancestry individuals | G | 0.982543 | 7E-99 | 98.155 | rs11591147 | 0.330722 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092885 | Free cholesterol levels in LDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-96 | 95.523 | rs11591147 | 0.324014 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS835765_H | GCST90092866 | Triglyceride levels in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-16 | 15.302 | rs11591147 | 0.124988 | triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092879 | Triglycerides to total lipids ratio in large VLDL | 115,071 European ancestry individuals | G | 0.982546 | 9E-50 | 49.046 | rs11591147 | 0.232351 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS837695_H | GCST90092862 | Total lipid levels in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-86 | 85.699 | rs11591147 | 0.306902 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS837953_H | GCST90092861 | Free cholesterol to total lipids ratio in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-34 | 33.699 | rs11591147 | 0.182593 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS838299_H | GCST90092857 | Cholesterol to total lipids ratio in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 9E-33 | 32.046 | rs11591147 | 0.181934 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS838979_H | GCST90018877 | Myocardial infarction | 20,917 European ancestry cases, 440,906 European ancestry controls, 14,992 East Asian ancestry cases, 146,214 East Asian ancestry controls | T | NR | 6E-17 | 16.222 | rs11591147 | 0.3174 | myocardial infarction (EFO:0000612) |
PMID:34594039 |
GWAS838983_H | GCST90092884 | Cholesteryl ester levels in LDL | 115,082 European ancestry individuals | G | 0.982543 | 8E-77 | 76.097 | rs11591147 | 0.29102 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092867 | Triglycerides to total lipids ratio in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-35 | 34.222 | rs11591147 | 0.188325 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90096812 | PCSK9 levels | 12,721 European ancestry individuals | T | 0.0144343196167133 | 9E-49 | 48.046 | rs11591147 | 0.29342 | proprotein convertase subtilisin/kexin type 9 measurement (EFO:0009312) |
PMID:34590679 |
None Available | GCST90086077 | Dyslipidemia | 30,244 European ancestry cases, 26,393 European ancestry controls | T | 0.014 | 4E-28 | 27.398 | rs11591147 | 0.52 | metabolic syndrome (EFO:0000195) |
PMID:33893285 |
None Available | GCST90096813 | PCSK9 levels | 10,186 European ancestry statin-free individuals | T | 0.0144343196167133 | 2E-46 | 45.699 | rs11591147 | 0.31965 | proprotein convertase subtilisin/kexin type 9 measurement (EFO:0009312) |
PMID:34590679 |
None Available | GCST90092853 | Phospholipids to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-45 | 44.302 | rs11591147 | 0.213601 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS841288_H | GCST90092864 | Phospholipid levels in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-90 | 89.398 | rs11591147 | 0.314459 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS842115_H | GCST90092858 | Cholesteryl ester levels in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-81 | 80.398 | rs11591147 | 0.297334 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092856 | Cholesterol levels in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-86 | 85.699 | rs11591147 | 0.306667 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS843619_H | GCST90092860 | Free cholesterol levels in large LDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-97 | 96.523 | rs11591147 | 0.323486 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092847 | Cholesteryl esters to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-10 | 9.222 | rs11591147 | 0.0927373 | cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS847693_H | GCST90019496 | Apolipoprotein B levels | 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals | T | NR | 8E-521 | 520.097 | rs11591147 | 0.4501 | apolipoprotein B measurement (EFO:0004615) |
PMID:33462484 |
None Available | GCST90088969 | Serum levels of protein PCSK9 | 5,350 Icelandic ancestry individuals | T | 0.01176 | 2E-41 | 40.699 | rs11591147 | 1.09951 | proprotein convertase subtilisin/kexin type 9 measurement (EFO:0009312) |
PMID:35078996 |
GWAS850937_H | GCST90090076 | Serum levels of protein PCSK9 | 5,363 Icelandic ancestry individuals | T | 0.01176 | 6E-32 | 31.222 | rs11591147 | 1.0396 | proprotein convertase subtilisin/kexin type 9 measurement (EFO:0009312) |
PMID:35078996 |
None Available | GCST012232 | Lipoprotein (a) levels | 348,591 European ancestry individuals, 6,000 African ancestry individuals, 9,116 Asian ancestry individuals, 7,505 individuals | G | NR | 5E-13 | 12.302 | rs11591147 | 0.039901 | lipoprotein A measurement (EFO:0006925) |
PMID:33730874 |
None Available | GCST90092889 | Average diameter for LDL particles | 115,082 European ancestry individuals | G | 0.982543 | 9E-18 | 17.046 | rs11591147 | 0.131785 | low density lipoprotein particle size measurement (EFO:0008593) |
PMID:35213538 |
None Available | GCST90092890 | Triglyceride levels in LDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-12 | 12 | rs11591147 | 0.109059 | triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS864038_H | GCST90092888 | Phospholipid levels in LDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-89 | 88.523 | rs11591147 | 0.3144 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092886 | Total lipid levels in LDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-83 | 82.222 | rs11591147 | 0.302525 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
None Available | GCST90092887 | Concentration of LDL particles | 115,082 European ancestry individuals | G | 0.982543 | 2E-92 | 91.699 | rs11591147 | 0.32044 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90139843 | Palmitoyl sphingomyelin (d18:1/16:0) levels | 6,136 Finnish ancestry individuals | T | NR | 1E-16 | 16 | rs11591147 | 0.37 | palmitoyl sphingomyelin (d18:1/16:0) measurement (EFO:0800300) |
PMID:35347128 |
GWAS885192_H | GCST90092838 | Concentration of IDL particles | 115,082 European ancestry individuals | G | 0.982543 | 8E-110 | 109.097 | rs11591147 | 0.346654 | intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS887249_H | GCST90104005 | Familial combined hyperlipidemia defined by Dutch criteria | 17,485 British ancestry cases, 331,737 British ancestry controls | G | 0.982411 | 9E-21 | 20.046 | rs11591147 | 0.450003 | PMID:34906840 | |
None Available | GCST90092841 | Triglyceride levels in IDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-11 | 10.699 | rs11591147 | 0.102722 | triglyceride measurement (EFO:0004530) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90129544 | Coronary artery disease or von Willebrand factor levels (pleiotropy) | 172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 46,354 European, African American or Hispanic individuals with measurements | ? | NR | 5E-18 | 17.302 | rs11591147 | N/A | von Willebrand factor measurement (EFO:0004629) coronary artery disease (EFO:0001645) |
PMID:35285134 |
GWAS888080_H | GCST90104006 | Familial combined hyperlipidemia defined by Consensus criteria | 39,961 British ancestry cases, 309,261 British ancestry controls | G | 0.982411 | 9E-76 | 75.046 | rs11591147 | 0.623922 | PMID:34906840 | |
GWAS888439_H | GCST90092810 | Ratio of apolipoprotein B to apolipoprotein A1 levels | 115,082 European ancestry individuals | G | 0.982543 | 1E-86 | 86 | rs11591147 | 0.305326 | apolipoprotein A 1 measurement (EFO:0004614) apolipoprotein B measurement (EFO:0004615) |
PMID:35213538 |
None Available | GCST90129543 | Coronary artery disease or factor VIII levels (pleiotropy) | 172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 32,610 European, African American, East Asian, South Asian or Hispanic individuals with measurements | ? | NR | 5E-18 | 17.302 | rs11591147 | N/A | factor VIII measurement (EFO:0004630) coronary artery disease (EFO:0001645) |
PMID:35285134 |
None Available | GCST90104007 | Familial combined hyperlipidemia defined by Mexico criteria | 5,153 British ancestry cases, 344,069 British ancestry controls | G | 0.982411 | 4E-13 | 12.398 | rs11591147 | 0.676738 | PMID:34906840 | |
None Available | GCST90092812 | Total cholines levels | 115,006 European ancestry individuals | G | 0.982536 | 1E-13 | 13 | rs11591147 | 0.109707 | choline measurement (EFO:0010116) |
PMID:35213538 |
GWAS889372_H | GCST90092839 | Phospholipid levels in IDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-103 | 102.699 | rs11591147 | 0.327491 | phospholipid measurement (EFO:0004639) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS889995_H | GCST90092834 | Cholesteryl esters to total lipids ratio in IDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-18 | 17.155 | rs11591147 | 0.1319 | cholesteryl esters:total lipids ratio (EFO:0020944) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS891704_H | GCST90092837 | Total lipid levels in IDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-98 | 97.155 | rs11591147 | 0.319329 | lipid measurement (EFO:0004529) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS893082_H | GCST90092836 | Free cholesterol to total lipids ratio in IDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-21 | 21 | rs11591147 | 0.149405 | free cholesterol:total lipids ratio (EFO:0020945) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS893341_H | GCST90092835 | Free cholesterol levels in IDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-101 | 101 | rs11591147 | 0.326041 | free cholesterol measurement (EFO:0008591) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST90104003 | Familial combined hyperlipidemia defined by Brunzell criteria | 3,838 British ancestry cases, 345,384 British ancestry controls | G | 0.982411 | 1E-8 | 8 | rs11591147 | 0.603121 | PMID:34906840 | |
None Available | GCST90104004 | Familial combined hyperlipidemia defined by Goldstein criteria | 1,688 British ancestry cases, 347,534 British ancestry controls | G | 0.982411 | 0.000009 | 5.046 | rs11591147 | 0.732224 | PMID:34906840 | |
GWAS902441_H | GCST90092915 | Triglycerides to total lipids ratio in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-40 | 39.302 | rs11591147 | 0.204022 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS902477_H | GCST90092930 | Total cholesterol minus HDL-C levels | 115,082 European ancestry individuals | G | 0.982543 | 5E-88 | 87.302 | rs11591147 | 0.311201 | total cholesterol measurement (EFO:0004574) |
PMID:35213538 |
GWAS902582_H | GCST90092933 | Omega-6 fatty acid levels | 115,006 European ancestry individuals | G | 0.982536 | 4E-27 | 26.398 | rs11591147 | 0.165697 | omega-6 polyunsaturated fatty acid measurement (EFO:0005680) |
PMID:35213538 |
None Available | GCST90092914 | Triglyceride levels in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-9 | 9 | rs11591147 | 0.0938653 | triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS903671_H | GCST90092927 | Triglycerides to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-74 | 73.699 | rs11591147 | 0.270634 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092908 | Free cholesterol levels in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-86 | 85.699 | rs11591147 | 0.309686 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092931 | Omega-3 fatty acid levels | 115,006 European ancestry individuals | G | 0.982536 | 4E-10 | 9.398 | rs11591147 | 0.0941458 | omega-3 polyunsaturated fatty acid measurement (EFO:0010119) |
PMID:35213538 |
GWAS906313_H | GCST90092912 | Phospholipid levels in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-74 | 73.302 | rs11591147 | 0.286793 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092909 | Free cholesterol to total lipids ratio in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-13 | 12.398 | rs11591147 | 0.108907 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS906811_H | GCST90092918 | Cholesteryl ester levels in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-108 | 107.222 | rs11591147 | 0.344073 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS907094_H | GCST90092904 | Cholesterol levels in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-69 | 68.398 | rs11591147 | 0.27701 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90092906 | Cholesteryl ester levels in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-60 | 59.523 | rs11591147 | 0.257865 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS910326_H | GCST90092905 | Cholesterol to total lipids ratio in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-21 | 20.302 | rs11591147 | 0.14823 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS910431_H | GCST90432152 | Abdominal aortic aneurysm | 37,214 European ancestry cases, 997,776 European ancestry controls, 2,007 African ancestry cases, 88,331 African ancestry controls | ? | NR | 7E-16 | 15.155 | rs11591147 | 0.3259 | Abdominal Aortic Aneurysm (EFO:0004214) |
PMID:37845353 |
None Available | GCST90011734 | Forns index in high alcohol intake | 33,437 British ancestry individuals | ? | 0.01754 | 8E-12 | 11.097 | rs11591147 | 0.01217 | liver fibrosis measurement (EFO:0010576) |
PMID:32561361 |
None Available | GCST90090991 | Total cholesterol levels | 17,701 African American individuals, 22,954 Hispanics ancestry individuals, 2,387 East Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals, 22,912 European ancestry individuals | ? | NR | 9E-25 | 24.046 | rs11591147 | 0.48 | total cholesterol measurement (EFO:0004574) |
PMID:32226016 |
GWAS915491_H | GCST90129545 | Coronary artery disease or factor XI levels (pleiotropy) | 172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 16,169 European ancestry individuals with measurements | ? | NR | 6E-18 | 17.222 | rs11591147 | N/A | factor XI measurement (EFO:0004694) coronary artery disease (EFO:0001645) |
PMID:35285134 |
None Available | GCST90092845 | Cholesterol to total lipids ratio in large HDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-16 | 15.699 | rs11591147 | 0.121975 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90090990 | Low density lipoprotein cholesterol levels | 17,222 African American individuals, 22,406 Hispanics ancestry individuals, 2,316 East Asian ancestry individuals, 1,900 Native Hawaiian ancestry individuals, 591 Native American ancestry individuals, 321 individuals, 22,331 European ancestry individuals | ? | NR | 4E-32 | 31.398 | rs11591147 | 0.548 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:32226016 |
GWAS916988_H | GCST90129546 | Coronary artery disease or fibrinogen levels (pleiotropy) | 172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 120,246 European ancestry individuals with measurements | ? | NR | 4E-18 | 17.398 | rs11591147 | N/A | fibrinogen measurement (EFO:0004623) coronary artery disease (EFO:0001645) |
PMID:35285134 |
None Available | GCST90060507 | Sphingomyelin_42:2_[M+OAc]1- levels | 13,814 British ancestry individuals | T | NR | 3E-10 | 9.523 | rs11591147 | 0.207321 | sphingomyelin measurement (EFO:0010118) |
PMID:34503513 |
GWAS918446_H | GCST90092832 | Cholesterol to total lipids ratio in IDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-29 | 29 | rs11591147 | 0.172523 | cholesterol:total lipids ratio (EFO:0020943) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS918535_H | GCST90092831 | Cholesterol levels in IDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-96 | 96 | rs11591147 | 0.317132 | total cholesterol measurement (EFO:0004574) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS918878_H | GCST90092833 | Cholesteryl ester levels in IDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-93 | 92.699 | rs11591147 | 0.31172 | cholesteryl ester measurement (EFO:0010351) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
GWAS919143_H | GCST90092842 | Triglycerides to total lipids ratio in IDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-41 | 40.523 | rs11591147 | 0.20278 | triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:35213538 |
None Available | GCST008086 | LDL cholesterol levels in current drinkers | 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals | T | NR | 1E-101 | 101 | rs11591147 | 16.42 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30698716 |
GWAS927178_H | GCST008086 | LDL cholesterol levels in current drinkers | 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals | T | NR | 2E-97 | 96.699 | rs11591147 | 16.37 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:30698716 |
GWAS928097_H | GCST003665 | Free cholesterol levels in large LDL | 21,555 European ancestry individuals | ? | NR | 3E-61 | 60.523 | rs11591147 | 0.5335034 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:27005778 |
None Available | GCST90092900 | Phospholipid levels in medium HDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-16 | 15.222 | rs11591147 | 0.118904 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092897 | Free cholesterol to total lipids ratio in medium HDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-9 | 8.302 | rs11591147 | 0.0814009 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092898 | Total lipid levels in medium HDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-13 | 12.155 | rs11591147 | 0.104648 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092894 | Cholesteryl ester levels in medium HDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-10 | 10 | rs11591147 | 0.0939653 | cholesteryl ester measurement (EFO:0010351) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS932968_H | GCST90019501 | Total cholesterol levels | 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals | T | NR | 4E-494 | 493.398 | rs11591147 | 0.4371 | total cholesterol measurement (EFO:0004574) |
PMID:33462484 |
None Available | GCST90092917 | Cholesterol to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-66 | 65.302 | rs11591147 | 0.253651 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
None Available | GCST90092937 | Phosphatidylcholine levels | 115,006 European ancestry individuals | G | 0.982536 | 1E-8 | 8 | rs11591147 | 0.0835336 | phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092910 | Total lipid levels in medium LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-68 | 67.699 | rs11591147 | 0.275282 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS935252_H | GCST90092923 | Concentration of medium VLDL particles | 115,082 European ancestry individuals | G | 0.982543 | 6E-53 | 52.222 | rs11591147 | 0.240097 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092911 | Concentration of medium LDL particles | 115,082 European ancestry individuals | G | 0.982543 | 2E-69 | 68.699 | rs11591147 | 0.27799 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS936512_H | GCST90092924 | Phospholipid levels in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-58 | 58 | rs11591147 | 0.253243 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS936922_H | GCST90092916 | Cholesterol levels in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-96 | 95.699 | rs11591147 | 0.32703 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092938 | Phosphoglycerides levels | 115,006 European ancestry individuals | G | 0.982536 | 1E-8 | 8 | rs11591147 | 0.0841679 | phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS938381_H | GCST90092925 | Phospholipids to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-97 | 97 | rs11591147 | 0.316447 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS938890_H | GCST90092998 | Free cholesterol levels in VLDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-36 | 35.398 | rs11591147 | 0.195725 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90093001 | Phospholipid levels in VLDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-26 | 25.398 | rs11591147 | 0.163783 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092953 | Phospholipids to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-39 | 38.523 | rs11591147 | 0.199045 | phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS941740_H | GCST90092999 | Total lipid levels in VLDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-14 | 13.302 | rs11591147 | 0.116113 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
None Available | GCST90093000 | Concentration of VLDL particles | 115,082 European ancestry individuals | G | 0.982543 | 1E-41 | 41 | rs11591147 | 0.210914 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092920 | Free cholesterol levels in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-72 | 71.155 | rs11591147 | 0.281851 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS945298_H | GCST90092922 | Total lipid levels in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-36 | 36 | rs11591147 | 0.197244 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS946434_H | GCST90092997 | Cholesteryl ester levels in VLDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-70 | 69.523 | rs11591147 | 0.278681 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS947174_H | GCST90092919 | Cholesteryl esters to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 8E-59 | 58.097 | rs11591147 | 0.238043 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS947424_H | GCST90092921 | Free cholesterol to total lipids ratio in medium VLDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-83 | 82.523 | rs11591147 | 0.289129 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS949603_H | GCST90428110 | PCSK9 levels | 20,579 European ancestry individuals | G | 0.015 | 7E-189 | 188.155 | rs11591147 | 0.39 | PCSK9 protein measurement (EFO:0006899) |
PMID:37989062 |
GWAS949861_H | GCST90428111 | PCSK9 levels in statin-naive individuals | 15,390 European ancestry individuals | G | 0.015 | 5E-149 | 148.302 | rs11591147 | 0.39 | PCSK9 protein measurement (EFO:0006899) |
PMID:37989062 |
GWAS956716_H | GCST90092939 | Polyunsaturated fatty acid levels | 115,006 European ancestry individuals | G | 0.982536 | 6E-28 | 27.222 | rs11591147 | 0.167284 | polyunsaturated fatty acid measurement (EFO:0010733) |
PMID:35213538 |
None Available | GCST90092883 | LDL cholesterol levels | 115,082 European ancestry individuals | G | 0.982543 | 2E-83 | 82.699 | rs11591147 | 0.303215 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90093043 | Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL | 111,638 European ancestry individuals | G | 0.982573 | 2E-16 | 15.699 | rs11591147 | 0.131079 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
GWAS957709_H | GCST90093041 | Cholesterol to total lipids ratio in chylomicrons and extremely large VLDL | 111,638 European ancestry individuals | G | 0.982573 | 2E-9 | 8.699 | rs11591147 | 0.0954523 | chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
GWAS957876_H | GCST90092880 | Linoleic acid levels | 115,006 European ancestry individuals | G | 0.982536 | 5E-24 | 23.302 | rs11591147 | 0.155986 | linoleic acid measurement (EFO:0006807) |
PMID:35213538 |
GWAS958104_H | GCST90092985 | Total cholesterol levels | 115,082 European ancestry individuals | G | 0.982543 | 2E-71 | 70.699 | rs11591147 | 0.2722 | total cholesterol measurement (EFO:0004574) |
PMID:35213538 |
GWAS958604_H | GCST90019512 | Low density lipoprotein cholesterol levels | 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals | T | NR | 9E-591 | 590.046 | rs11591147 | 0.4782 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:33462484 |
GWAS958688_H | GCST90092809 | Apolipoprotein B levels | 115,082 European ancestry individuals | G | 0.982543 | 2E-94 | 93.699 | rs11591147 | 0.323815 | apolipoprotein B measurement (EFO:0004615) |
PMID:35213538 |
GWAS958869_H | GCST90092814 | Clinical LDL cholesterol levels | 115,082 European ancestry individuals | G | 0.982543 | 4E-95 | 94.398 | rs11591147 | 0.323797 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS958977_H | GCST90093039 | Triglycerides to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-65 | 64.699 | rs11591147 | 0.254105 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90092892 | Cholesterol levels in medium HDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-9 | 8.699 | rs11591147 | 0.0866095 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS960570_H | GCST90092988 | Total free cholesterol levels | 115,082 European ancestry individuals | G | 0.982543 | 1E-76 | 76 | rs11591147 | 0.284735 | free cholesterol measurement (EFO:0008591) |
PMID:35213538 |
None Available | GCST90140125 | Glycosyl ceramide (d18:1/20:0, d16:1/22:0) levels | 6,136 Finnish ancestry individuals | T | NR | 4E-12 | 11.398 | rs11591147 | 0.4 | glycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement (EFO:0800551) |
PMID:35347128 |
GWAS961568_H | GCST90092971 | Cholesteryl esters to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-88 | 87.155 | rs11591147 | 0.308006 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
None Available | GCST90093016 | Cholesterol levels in very large VLDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-16 | 15.398 | rs11591147 | 0.124929 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS961878_H | GCST90093029 | Cholesterol to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-55 | 54.222 | rs11591147 | 0.231585 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
None Available | GCST90132287 | Ideal cardiovascular health score (clinical and behavioral) | 119,129 European ancestry individuals, 16,495 African American individuals, 6,780 Hispanic individuals | T | 0.01 | 7E-16 | 15.155 | rs11591147 | 0.21 | clinical and behavioural ideal cardiovascular health (EFO:0007654) |
PMID:35613103 |
None Available | GCST90140166 | Palmitoyl-sphingosine-phosphoethanolamine (d18:1/16:0) levels | 6,136 Finnish ancestry individuals | T | NR | 3E-16 | 15.523 | rs11591147 | 0.38 | palmitoyl-sphingosine-phosphoethanolamine (d18:1/16:0) measurement (EFO:0800591) |
PMID:35347128 |
None Available | GCST90140208 | Cholesterol levels | 6,136 Finnish ancestry individuals | T | NR | 5E-14 | 13.302 | rs11591147 | 0.34 | total cholesterol measurement (EFO:0004574) |
PMID:35347128 |
GWAS963023_H | GCST90239655 | Low density lipoprotein cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 3E-1364 | 1363.523 | rs11591147 | N/A | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS963291_H | GCST90092974 | Total lipid levels in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 8E-28 | 27.097 | rs11591147 | 0.169587 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
None Available | GCST90092986 | Total esterified cholesterol levels | 115,082 European ancestry individuals | G | 0.982543 | 2E-68 | 67.699 | rs11591147 | 0.265257 | esterified cholesterol measurement (EFO:0008589) |
PMID:35213538 |
None Available | GCST90092972 | Free cholesterol levels in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-78 | 77.523 | rs11591147 | 0.294517 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS963713_H | GCST90140158 | Hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) levels | 6,136 Finnish ancestry individuals | T | NR | 4E-15 | 14.398 | rs11591147 | 0.35 | hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) measurement (EFO:0800583) |
PMID:35347128 |
GWAS965031_H | GCST90092958 | Cholesteryl ester levels in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-72 | 71.222 | rs11591147 | 0.282243 | cholesteryl ester measurement (EFO:0010351) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS966412_H | GCST90140027 | 1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) levels | 6,136 Finnish ancestry individuals | T | NR | 3E-11 | 10.523 | rs11591147 | 0.3 | 1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement (EFO:0800466) |
PMID:35347128 |
GWAS966448_H | GCST90092970 | Cholesteryl ester levels in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 9E-62 | 61.046 | rs11591147 | 0.259988 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS966687_H | GCST90092957 | Cholesterol to total lipids ratio in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-24 | 23.523 | rs11591147 | 0.160412 | cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS966886_H | GCST90092956 | Cholesterol levels in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-83 | 82.398 | rs11591147 | 0.304099 | total cholesterol measurement (EFO:0004574) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS966946_H | GCST90092973 | Free cholesterol to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-73 | 73 | rs11591147 | 0.271361 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS967351_H | GCST90239659 | Low density lipoprotein cholesterol levels | 48,057 Hispanic individuals | T | 0.00828729 | 3E-38 | 37.523 | rs11591147 | 0.485403 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
None Available | GCST90092899 | Concentration of medium HDL particles | 115,082 European ancestry individuals | G | 0.982543 | 1E-9 | 9 | rs11591147 | 0.0877732 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS968281_H | GCST90239658 | Low density lipoprotein cholesterol levels | 1,320,016 European ancestry individuals | T | 0.0163157 | 7E-1039 | 1038.155 | rs11591147 | 0.433696 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34887591 |
GWAS968987_H | GCST90092949 | Free cholesterol to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-58 | 57.155 | rs11591147 | 0.238926 | free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90092945 | Cholesterol to total lipids ratio in small HDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-17 | 17 | rs11591147 | 0.132121 | cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS969624_H | GCST90092943 | Remnant cholesterol (non-HDL, non-LDL -cholesterol) | 115,082 European ancestry individuals | G | 0.982543 | 6E-87 | 86.222 | rs11591147 | 0.308882 | remnant cholesterol measurement (EFO:0010815) |
PMID:35213538 |
GWAS969648_H | GCST90092976 | Phospholipid levels in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-56 | 55.523 | rs11591147 | 0.247599 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS969658_H | GCST90092977 | Phospholipids to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 7E-74 | 73.155 | rs11591147 | 0.272239 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
GWAS970116_H | GCST90239670 | Non-HDL cholesterol levels | 1,320,016 European ancestry individuals | T | 0.016294 | 4E-655 | 654.398 | rs11591147 | 0.410741 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS971657_H | GCST90093017 | Cholesterol to total lipids ratio in very large VLDL | 114,160 European ancestry individuals | G | 0.982599 | 9E-44 | 43.046 | rs11591147 | 0.209061 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
GWAS971801_H | GCST90179148 | Low-density lipoprotein levels (MTAG) | 361,194 European ancestry individuals | T | NR | 4E-44 | 43.398 | rs11591147 | 0.07333 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36376304 |
GWAS971815_H | GCST90018961 | LDL cholesterol | 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals | T | NR | 2E-335 | 334.699 | rs11591147 | 0.3485 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:34594039 |
GWAS972371_H | GCST90093021 | Free cholesterol to total lipids ratio in very large VLDL | 114,160 European ancestry individuals | G | 0.982599 | 1E-45 | 45 | rs11591147 | 0.216328 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
None Available | GCST90093028 | Cholesterol levels in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-94 | 93.699 | rs11591147 | 0.314264 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS974184_H | GCST90239677 | Total cholesterol levels | 48,057 Hispanic individuals | T | 0.00810973 | 9E-31 | 30.046 | rs11591147 | 0.426811 | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS974335_H | GCST90239667 | Non-HDL cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 8E-875 | 874.097 | rs11591147 | N/A | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
GWAS974636_H | GCST90092968 | Cholesterol levels in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-68 | 68 | rs11591147 | 0.275018 | total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS975101_H | GCST90092962 | Total lipid levels in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 4E-84 | 83.398 | rs11591147 | 0.305666 | low density lipoprotein cholesterol measurement (EFO:0004611) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS975506_H | GCST90093018 | Cholesteryl ester levels in very large VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-27 | 26.699 | rs11591147 | 0.167989 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS975736_H | GCST90092964 | Phospholipid levels in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-99 | 99 | rs11591147 | 0.332415 | low density lipoprotein cholesterol measurement (EFO:0004611) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90092989 | Total lipid levels in lipoprotein particles | 115,082 European ancestry individuals | G | 0.982543 | 1E-40 | 40 | rs11591147 | 0.206283 | lipid measurement (EFO:0004529) lipoprotein measurement (EFO:0004732) |
PMID:35213538 |
None Available | GCST90140038 | Glycosyl-N-palmitoyl-sphingosine (d18:1/16:0) levels | 6,136 Finnish ancestry individuals | T | NR | 3E-11 | 10.523 | rs11591147 | 0.3 | glycosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement (EFO:0800476) |
PMID:35347128 |
GWAS976565_H | GCST90092967 | Triglycerides to total lipids ratio in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-35 | 34.699 | rs11591147 | 0.187938 | triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90139957 | Palmitoyl dihydrosphingomyelin (d18:0/16:0) levels | 6,136 Finnish ancestry individuals | T | NR | 2E-18 | 17.699 | rs11591147 | 0.4 | palmitoyl dihydrosphingomyelin (d18:0/16:0) measurement (EFO:0800400) |
PMID:35347128 |
GWAS976990_H | GCST90092963 | Concentration of small LDL particles | 115,082 European ancestry individuals | G | 0.982543 | 3E-81 | 80.523 | rs11591147 | 0.300449 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS977056_H | GCST90132957 | Spread type: Flora Pro-Active/Benecol (UKB data field 1428_2) | 448,696 European ancestry individuals | G | 0.982454 | 3E-9 | 8.523 | rs11591147 | 0.0346076 | diet measurement (EFO:0008111) |
PMID:32193382 |
None Available | GCST90092961 | Free cholesterol to total lipids ratio in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-17 | 16.699 | rs11591147 | 0.128726 | low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS977203_H | GCST90092969 | Cholesterol to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-92 | 91.523 | rs11591147 | 0.310713 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943) |
PMID:35213538 |
GWAS977365_H | GCST90092960 | Free cholesterol levels in small LDL | 115,082 European ancestry individuals | G | 0.982543 | 8E-98 | 97.097 | rs11591147 | 0.329559 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
GWAS977865_H | GCST90239673 | Total cholesterol levels | 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals | ? | NR | 1E-1070 | 1070 | rs11591147 | N/A | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
None Available | GCST90139919 | Sphingomyelin (d18:1/24:1, d18:2/24:0) levels | 6,136 Finnish ancestry individuals | T | NR | 3E-13 | 12.523 | rs11591147 | 0.33 | sphingomyelin measurement (EFO:0010118) |
PMID:35347128 |
None Available | GCST90092987 | Total fatty acid levels | 115,006 European ancestry individuals | G | 0.982536 | 3E-12 | 11.523 | rs11591147 | 0.10863 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
None Available | GCST90239671 | Non-HDL cholesterol levels | 48,057 Hispanic individuals | T | 0.00718718 | 4E-21 | 20.398 | rs11591147 | 0.524412 | non-high density lipoprotein cholesterol measurement (EFO:0005689) |
PMID:34887591 |
None Available | GCST90092994 | Degree of unsaturation | 115,006 European ancestry individuals | G | 0.982536 | 8E-11 | 10.097 | rs11591147 | 0.0971407 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
GWAS978557_H | GCST90092982 | Sphingomyelin levels | 115,006 European ancestry individuals | G | 0.982536 | 5E-54 | 53.302 | rs11591147 | 0.227522 | sphingomyelin measurement (EFO:0010118) |
PMID:35213538 |
GWAS978685_H | GCST90092991 | Total phospholipid levels in lipoprotein particles | 115,082 European ancestry individuals | G | 0.982543 | 8E-26 | 25.097 | rs11591147 | 0.157164 | lipoprotein measurement (EFO:0004732) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
None Available | GCST90179195 | Free cholesterol levels in IDL | 7,142 European ancestry individuals | T | 0.02 | 3E-15 | 14.523 | rs11591147 | 0.48 | free cholesterol measurement (EFO:0008591) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:32150548 |
GWAS979254_H | GCST90092975 | Concentration of small VLDL particles | 115,082 European ancestry individuals | G | 0.982543 | 5E-26 | 25.302 | rs11591147 | 0.163232 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS979513_H | GCST90092979 | Triglycerides to total lipids ratio in small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-89 | 88.699 | rs11591147 | 0.303948 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS980047_H | GCST90092996 | VLDL cholesterol levels | 115,082 European ancestry individuals | G | 0.982543 | 2E-55 | 54.699 | rs11591147 | 0.246233 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90093034 | Total lipid levels in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-67 | 66.699 | rs11591147 | 0.266913 | very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529) |
PMID:35213538 |
GWAS980351_H | GCST90093030 | Cholesteryl ester levels in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-97 | 96.222 | rs11591147 | 0.316902 | cholesteryl ester measurement (EFO:0010351) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS980703_H | GCST90093025 | Phospholipids to total lipids ratio in very large VLDL | 114,160 European ancestry individuals | G | 0.982599 | 3E-54 | 53.523 | rs11591147 | 0.244698 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946) |
PMID:35213538 |
None Available | GCST90093033 | Free cholesterol to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-68 | 68 | rs11591147 | 0.273288 | very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945) |
PMID:35213538 |
GWAS981386_H | GCST90025188 | Total Cholesteryl ester levels | 6,057 European ancestry individuals | T | NR | 9E-14 | 13.046 | rs11591147 | N/A | cholesteryl ester measurement (EFO:0010351) |
PMID:35668104 |
None Available | GCST90093019 | Cholesteryl esters to total lipids ratio in very large VLDL | 114,160 European ancestry individuals | G | 0.982599 | 1E-40 | 40 | rs11591147 | 0.200937 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
None Available | GCST90093031 | Cholesteryl esters to total lipids ratio in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-48 | 48 | rs11591147 | 0.215908 | very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944) |
PMID:35213538 |
None Available | GCST90092980 | Saturated fatty acid levels | 115,006 European ancestry individuals | G | 0.982536 | 1E-8 | 8 | rs11591147 | 0.0882842 | fatty acid measurement (EFO:0005110) |
PMID:35213538 |
None Available | GCST90093027 | Triglycerides to total lipids ratio in very large VLDL | 114,160 European ancestry individuals | G | 0.982599 | 8E-59 | 58.097 | rs11591147 | 0.246654 | triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90093036 | Phospholipid levels in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 2E-64 | 63.699 | rs11591147 | 0.261364 | very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639) |
PMID:35213538 |
GWAS982570_H | GCST90093032 | Free cholesterol levels in very small VLDL | 115,082 European ancestry individuals | G | 0.982543 | 9E-82 | 81.046 | rs11591147 | 0.294853 | free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
None Available | GCST90093035 | Concentration of very small VLDL particles | 115,082 European ancestry individuals | G | 0.982543 | 5E-76 | 75.302 | rs11591147 | 0.285235 | very low density lipoprotein cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS983346_H | GCST90239676 | Total cholesterol levels | 1,320,016 European ancestry individuals | T | 0.0161905 | 2E-779 | 778.699 | rs11591147 | 0.37713 | total cholesterol measurement (EFO:0004574) |
PMID:34887591 |
GWAS986697_H | GCST90179147 | High-density lipoprotein levels (MTAG) | 361,194 European ancestry individuals | T | NR | 1E-22 | 22 | rs11591147 | 0.09803 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:36376304 |
None Available | GCST90092816 | Docosahexaenoic acid levels | 115,006 European ancestry individuals | G | 0.982536 | 6E-14 | 13.222 | rs11591147 | 0.112079 | docosahexaenoic acid measurement (EFO:0007761) |
PMID:35213538 |
None Available | GCST90093010 | Total lipid levels in very large HDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-14 | 13.523 | rs11591147 | 0.107163 | lipid measurement (EFO:0004529) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS993550_H | GCST90093004 | Cholesterol levels in very large HDL | 115,082 European ancestry individuals | G | 0.982543 | 6E-21 | 20.222 | rs11591147 | 0.133317 | total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
GWAS994303_H | GCST90093008 | Free cholesterol levels in very large HDL | 115,082 European ancestry individuals | G | 0.982543 | 5E-34 | 33.302 | rs11591147 | 0.178287 | free cholesterol measurement (EFO:0008591) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90093012 | Phospholipid levels in very large HDL | 115,082 European ancestry individuals | G | 0.982543 | 1E-8 | 8 | rs11591147 | 0.0808208 | phospholipid measurement (EFO:0004639) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90093006 | Cholesteryl ester levels in very large HDL | 115,082 European ancestry individuals | G | 0.982543 | 3E-17 | 16.523 | rs11591147 | 0.11885 | cholesteryl ester measurement (EFO:0010351) high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90093011 | Concentration of very large HDL particles | 115,082 European ancestry individuals | G | 0.982543 | 2E-21 | 20.699 | rs11591147 | 0.134641 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:35213538 |
None Available | GCST90018989 | Medication use (HMG CoA reductase inhibitors) | 73,475 European ancestry cases, 216,910 European ancestry controls, 33,295 East Asian ancestry cases, 145,431 East Asian ancestry controls | T | NR | 9E-64 | 63.046 | rs11591147 | 0.3623 | HMG CoA reductase inhibitor use measurement (EFO:0009932) |
PMID:34594039 |
GWAS1012470_H | GCST90018974 | Total cholesterol levels | 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals | T | NR | 2E-278 | 277.699 | rs11591147 | 0.3124 | total cholesterol measurement (EFO:0004574) |
PMID:34594039 |
None Available | GCST008370 | Ischemic heart disease (PheCode 411) | 31,355 British ancestry cases, 377,103 British ancestry controls | T | 0.018 | 2E-12 | 11.699 | rs11591147 | N/A | coronary artery disease (EFO:0001645) |
PMID:30104761 |
None Available | GCST90301976 | Total cholesterol to total lipids ratio in IDL | 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals | T | 0.0289 | 9E-71 | 70.046 | rs11591147 | 0.2576 | cholesterol:total lipids ratio (EFO:0020943) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:38448586 |
None Available | GCST90448682 | 25-hydroxyvitamin D levels (skin colour stratified) | 409,654 European ancestry individuals | G | 0.98 | 1E-9 | 9 | rs11591147 | 0.046 | vitamin D measurement (EFO:0004631) |
PMID:37963177 |
None Available | GCST90446533 | Angina | 25,257 European ancestry cases, 433,881 European ancestry controls | ? | NR | 1E-9 | 9 | rs11591147 | N/A | angina pectoris (EFO:0003913) |
PMID:37947095 |
None Available | GCST90446535 | Cardiovascular disease | 44,238 European ancestry cases, 414,900 European ancestry controls | ? | NR | 6E-13 | 12.222 | rs11591147 | N/A | cardiovascular disease (EFO:0000319) |
PMID:37947095 |
None Available | GCST90446534 | Coronary heart disease | 38,687 European ancestry cases, 420,451 European ancestry controls | ? | NR | 2E-14 | 13.699 | rs11591147 | N/A | coronary artery disease (EFO:0001645) |
PMID:37947095 |
None Available | GCST90446532 | Myocardial infarction | 16,602 European ancestry cases, 442,536 European ancestry controls | ? | NR | 2E-9 | 8.699 | rs11591147 | N/A | myocardial infarction (EFO:0000612) |
PMID:37947095 |
Database | Acc Id | Source(s) |
GWAS Catalog | GCST009240 | GWAS Catalog |
GCST90092894 | GWAS Catalog | |
GCST90277250 | GWAS Catalog | |
GCST90277374 | GWAS Catalog | |
GCST90301945 | GWAS Catalog |
Note Type | Note | Reference |
---|