LDLPS20_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: LDLPS20_H (Low density lipoprotein particle size QTL 21 (human)) Homo sapiens

Symbol: LDLPS20_H
Name: Low density lipoprotein particle size QTL 21 (human)
RGD ID: 1578620
Trait: LDL particle size
LOD Score: 2.04
P Value: 4.6E-4
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37152,996,788 - 78,996,788RGD_MAPPER_PIPELINEGRCh37
Build 36152,767,158 - 78,767,158RGDNCBI36
Cross Type: Not Available
Population Stats: 681 French-Canadian families in the Quebec Family Study



References

References - curated
# Reference Title Reference Citation
1. Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter. Bosse Y, etal., Circulation 2003 May 13;107(18):2361-8. Epub 2003 May 5.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (LEPR)
Human AssemblyChrPosition (strand)Source
GRCh38165,420,652 - 65,641,559 (+)NCBI
GRCh38.p14 Ensembl165,420,652 - 65,641,559 (+)Ensembl
GRCh37165,886,335 - 66,107,242 (+)NCBI
Build 36165,658,906 - 65,875,410 (+)NCBI
Build 34165,598,338 - 65,814,843NCBI
Celera164,176,916 - 64,393,787 (+)NCBI
Cytogenetic Map1p31.3NCBI
HuRef163,995,123 - 64,212,195 (+)NCBI
CHM1_1166,002,606 - 66,219,234 (+)NCBI
T2T-CHM13v2.0165,298,629 - 65,519,352 (+)NCBI


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cand_genes PLA2G2D,PLA2G2A,PLA2G5,APOER2,FABP3,CPT2,ABCD3,HMGCS2 1559066
qtl_population 681 French-Canadian families in the Quebec Family Study 1559066
qtl_population_details 236 nuclear families; 137 fathers, 194 mothers, 148 sons and 202 daughters; LDL particle size varied from 261 to 264.4 angstroms and plasma triglyceride varied from 1.27 to 1.98 mmol/L 1559066
qtl_statistics_details SAGE 4.0 and SIBPAL2; analysis was for peak particle diameter adjusted for age, and BMI 1559066