Msantd7 (Myb/SANT DNA binding domain containing 7) - Rat Genome Database

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Gene: Msantd7 (Myb/SANT DNA binding domain containing 7) Rattus norvegicus
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Symbol: Msantd7
Name: Myb/SANT DNA binding domain containing 7
RGD ID: 7640129
Description: Orthologous to human MSANTD7 (Myb/SANT DNA binding domain containing 7); INTERACTS WITH 1,2-dimethylhydrazine (ortholog); 17alpha-ethynylestradiol (ortholog); 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102547897; uncharacterized LOC102547897; uncharacterized protein LOC102547897; zinc finger and SCAN domain containing 29
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,638,088 - 79,644,688 (+)NCBIGRCr8
mRatBN7.21774,728,927 - 74,735,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,728,811 - 74,736,094 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01778,739,291 - 78,743,299 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,739,389 - 78,741,032 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,383,117 - 80,387,119 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1774,118,504 - 74,122,512 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Msantd7Rat1,2-dimethylhydrazine multiple interactionsISOHspa14 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HSPA14 mRNACTDPMID:22206623
Msantd7Rat17alpha-ethynylestradiol increases expressionISOHspa14 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of HSPA14 mRNACTDPMID:17942748
Msantd7Rat4,4'-sulfonyldiphenol increases expressionISOHspa14 (Mus musculus)6480464bisphenol S results in increased expression of HSPA14 mRNACTDPMID:39298647
Msantd7Ratarsenite(3-) decreases expressionISOHspa14 (Mus musculus)6480464arsenite results in decreased expression of HSPA14 mRNACTDPMID:33053406
Msantd7Ratchlorpyrifos decreases expressionISOHspa14 (Mus musculus)6480464Chlorpyrifos results in decreased expression of HSPA14 mRNACTDPMID:37019170
Msantd7Ratdibenzo[a,l]pyrene decreases expressionISOHspa14 (Mus musculus)6480464dibenzo(a and l)pyrene results in decreased expression of HSPA14 mRNACTDPMID:25908611
Msantd7Ratdibutyl phthalate decreases expressionISOHspa14 (Mus musculus)6480464Dibutyl Phthalate results in decreased expression of HSPA14 mRNACTDPMID:21266533
Msantd7Ratethanol affects expressionISOHspa14 (Mus musculus)6480464Ethanol affects the expression of HSPA14 mRNACTDPMID:30319688
Msantd7Ratfolic acid multiple interactionsISOHspa14 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HSPA14 mRNACTDPMID:22206623
Msantd7Ratniclosamide decreases expressionISOMSANTD7 (Homo sapiens)6480464Niclosamide results in decreased expression of MSANTD7 mRNACTDPMID:36318118
Msantd7Ratpirinixic acid multiple interactionsISOHspa14 (Mus musculus)6480464PPARA protein affects the reaction [pirinixic acid results in increased expression of HSPA14 mRNA]CTDPMID:21318169
Msantd7Ratpirinixic acid increases expressionISOHspa14 (Mus musculus)6480464pirinixic acid results in increased expression of HSPA14 mRNACTDPMID:21318169
Msantd7Ratpregnenolone 16alpha-carbonitrile increases expressionISOHspa14 (Mus musculus)6480464Pregnenolone Carbonitrile results in increased expression of HSPA14 mRNACTDPMID:28903501
Msantd7Ratsodium arsenate increases expressionISOHspa14 (Mus musculus)6480464sodium arsenate results in increased expression of HSPA14 mRNACTDPMID:30953684
Msantd7Rattitanium dioxide decreases methylationISOHspa14 (Mus musculus)6480464titanium dioxide results in decreased methylation of HSPA14 geneCTDPMID:35295148

1 to 15 of 15 rows

#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


Msantd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,638,088 - 79,644,688 (+)NCBIGRCr8
mRatBN7.21774,728,927 - 74,735,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,728,811 - 74,736,094 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01778,739,291 - 78,743,299 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,739,389 - 78,741,032 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,383,117 - 80,387,119 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1774,118,504 - 74,122,512 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
MSANTD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,838,306 - 14,846,999 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,838,302 - 14,846,999 (+)EnsemblGRCh38hg38GRCh38
GRCh371014,880,305 - 14,888,998 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,920,267 - 14,953,746 (+)NCBINCBI36Build 36hg18NCBI36
Build 341014,920,345 - 14,953,744NCBI
Celera1014,808,301 - 14,841,780 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,794,951 - 14,795,473 (+)NCBIHuRef
CHM1_11014,884,703 - 14,885,225 (+)NCBICHM1_1
T2T-CHM13v2.01014,852,271 - 14,860,964 (+)NCBIT2T-CHM13v2.0
Hspa14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,489,891 - 3,513,851 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,489,887 - 3,513,851 (-)EnsemblGRCm39 Ensembl
GRCm3823,488,854 - 3,512,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,504,527 - 3,512,790 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl23,488,850 - 3,512,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv3723,406,126 - 3,430,086 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3623,406,126 - 3,430,086 (-)NCBIMGSCv36mm8
Celera23,439,507 - 3,463,457 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.97NCBI
MSANTD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,367,938 - 27,372,801 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,373,274 - 27,378,148 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,841,958 - 14,850,659 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl1015,169,747 - 15,204,263 (+)Ensemblpanpan1.1panPan2
HSPA14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,757,326 - 21,795,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,757,289 - 21,853,468 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha218,870,584 - 18,908,738 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,058,964 - 22,097,121 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,055,925 - 22,097,256 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,259,344 - 19,297,491 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,094,074 - 20,132,238 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,720,740 - 20,758,898 (-)NCBIUU_Cfam_GSD_1.0
Msantd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,857,515 - 6,861,559 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,410,338 - 1,412,221 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,410,350 - 1,414,935 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSANTD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605120,400,097 - 20,406,480 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Msantd7
28 total Variants

1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat

1 to 10 of 25 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


RefSeq Transcripts NM_001417572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020384   ⟹   ENSRNOP00000020384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1778,739,389 - 78,741,032 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099175   ⟹   ENSRNOP00000077665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1774,728,811 - 74,736,094 (+)Ensembl
RefSeq Acc Id: NM_001417572   ⟹   NP_001404501
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,638,088 - 79,644,688 (+)NCBI
mRatBN7.21774,728,927 - 74,735,527 (+)NCBI
Protein RefSeqs NP_001404501 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000077665.1
Ensembl Acc Id: ENSRNOP00000020384   ⟸   ENSRNOT00000020384
Ensembl Acc Id: ENSRNOP00000077665   ⟸   ENSRNOT00000099175
RefSeq Acc Id: NP_001404501   ⟸   NM_001417572
- UniProtKB: D3ZUB3 (UniProtKB/TrEMBL),   A6JM13 (UniProtKB/TrEMBL)
Myb/SANT-like DNA-binding

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUB3-F1-model_v2 AlphaFold D3ZUB3 1-361 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 15 of 15 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-8652 BioCyc
Ensembl Genes ENSRNOG00000015196 Ensembl
  ENSRNOG00000065772 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000099175.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Myb_DNA-bind_4 UniProtKB/TrEMBL
NCBI Gene LOC102547897 ENTREZGENE
PANTHER HEAT SHOCK 70 KDA PROTEIN 14 UniProtKB/TrEMBL
  MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam Myb_DNA-bind_4 UniProtKB/TrEMBL
PhenoGen Msantd7 PhenoGen
RatGTEx ENSRNOG00000015196 RatGTEx
  ENSRNOG00000065772 RatGTEx
UniProt A6JM13 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUB3 ENTREZGENE, UniProtKB/TrEMBL
1 to 15 of 15 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-09 Msantd7  Myb/SANT DNA binding domain containing 7  LOC102547897  uncharacterized LOC102547897  Name and Symbol changed 629549 APPROVED
2013-12-18 LOC102547897  uncharacterized LOC102547897      Symbol and Name status set to provisional 70820 PROVISIONAL