Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ddx46 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Ddx46 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of DDX46 mRNA | CTD | PMID:22206623 | Ddx46 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Ddx46 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DDX46 mRNA | CTD | PMID:17942748 | Ddx46 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ddx46 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DDX46 mRNA | CTD | PMID:17942748 | Ddx46 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DDX46 mRNA | CTD | PMID:34747641 | Ddx46 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ddx46 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DDX46 mRNA | CTD | PMID:21570461 and PMID:26377647 | Ddx46 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Ddx46 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of DDX46 mRNA | CTD | PMID:21346803 | Ddx46 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of DDX46 mRNA | CTD | PMID:21346803 | Ddx46 | Rat | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of DDX46 mRNA | CTD | PMID:19162173 | Ddx46 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | DDX46 (Homo sapiens) | 6480464 | Decitabine affects the expression of DDX46 mRNA | CTD | PMID:23300844 | Ddx46 | Rat | acrolein | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DDX46 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DDX46 mRNA | CTD | PMID:32699268 | Ddx46 | Rat | aflatoxin B1 | increases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of DDX46 mRNA | CTD | PMID:19770486 | Ddx46 | Rat | aflatoxin B1 | increases methylation | ISO | DDX46 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of DDX46 intron | CTD | PMID:30157460 | Ddx46 | Rat | allethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DDX46 protein | CTD | PMID:34896426 | Ddx46 | Rat | alpha-pinene | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DDX46 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DDX46 mRNA | CTD | PMID:32699268 | Ddx46 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DDX46 mRNA | CTD | PMID:16483693 | Ddx46 | Rat | aristolochic acid A | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DDX46 mRNA | CTD | PMID:33212167 | Ddx46 | Rat | Aroclor 1254 | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of DDX46 mRNA | CTD | PMID:23650126 | Ddx46 | Rat | atrazine | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of DDX46 mRNA | CTD | PMID:22378314 | Ddx46 | Rat | benzo[a]pyrene | increases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DDX46 mRNA | CTD | PMID:22228805 | Ddx46 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DDX46 mRNA | CTD | PMID:25181051 more ... | Ddx46 | Rat | bisphenol A | decreases methylation | ISO | DDX46 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of DDX46 gene | CTD | PMID:31601247 | Ddx46 | Rat | bisphenol A | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of DDX46 protein | CTD | PMID:31675489 | Ddx46 | Rat | bisphenol A | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DDX46 mRNA | CTD | PMID:33221593 | Ddx46 | Rat | bisphenol A | affects expression | ISO | DDX46 (Homo sapiens) | 6480464 | bisphenol A affects the expression of DDX46 mRNA | CTD | PMID:33670352 | Ddx46 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of DDX46 gene | CTD | PMID:28505145 | Ddx46 | Rat | butanal | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of DDX46 mRNA | CTD | PMID:26079696 | Ddx46 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of DDX46 promoter | CTD | PMID:22457795 | Ddx46 | Rat | caffeine | affects phosphorylation | ISO | DDX46 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of DDX46 protein | CTD | PMID:35688186 | Ddx46 | Rat | cannabidiol | increases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of DDX46 protein | CTD | PMID:34122009 | Ddx46 | Rat | carbon nanotube | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Ddx46 | Rat | carbon nanotube | increases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of DDX46 mRNA | CTD | PMID:25620056 | Ddx46 | Rat | CGP 52608 | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DDX46 gene] | CTD | PMID:28238834 | Ddx46 | Rat | cisplatin | affects expression | ISO | DDX46 (Homo sapiens) | 6480464 | Cisplatin affects the expression of DDX46 mRNA | CTD | PMID:23300844 | Ddx46 | Rat | clozapine | increases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Clozapine results in increased expression of DDX46 protein | CTD | PMID:34122009 | Ddx46 | Rat | copper atom | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of DDX46 mRNA | CTD | PMID:20971185 | Ddx46 | Rat | copper(0) | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of DDX46 mRNA | CTD | PMID:20971185 | Ddx46 | Rat | coumarin | increases phosphorylation | ISO | DDX46 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of DDX46 protein | CTD | PMID:35688186 | Ddx46 | Rat | Cuprizon | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Haloperidol] results in increased expression of DDX46 protein | CTD | PMID:34122009 | Ddx46 | Rat | cyclosporin A | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of DDX46 mRNA | CTD | PMID:25562108 | Ddx46 | Rat | cyhalothrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DDX46 protein | CTD | PMID:34896426 | Ddx46 | Rat | cylindrospermopsin | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | cylindrospermopsin results in decreased expression of DDX46 mRNA | CTD | PMID:24921660 | Ddx46 | Rat | cypermethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DDX46 protein | CTD | PMID:34896426 | Ddx46 | Rat | cyproconazole | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | cyproconazole results in decreased expression of DDX46 mRNA | CTD | PMID:22334560 | Ddx46 | Rat | dibutyl phthalate | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of DDX46 mRNA | CTD | PMID:21266533 | Ddx46 | Rat | doxorubicin | increases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of DDX46 mRNA | CTD | PMID:29803840 | Ddx46 | Rat | enzyme inhibitor | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DDX46 protein | CTD | PMID:23301498 | Ddx46 | Rat | epoxiconazole | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of DDX46 mRNA | CTD | PMID:22334560 and PMID:23970803 | Ddx46 | Rat | ethanol | affects splicing | ISO | Ddx46 (Mus musculus) | 6480464 | Ethanol affects the splicing of DDX46 mRNA | CTD | PMID:30319688 | Ddx46 | Rat | ethyl methanesulfonate | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of DDX46 mRNA | CTD | PMID:23649840 | Ddx46 | Rat | fenvalerate | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DDX46 protein | CTD | PMID:34896426 | Ddx46 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DDX46 mRNA | CTD | PMID:24136188 | Ddx46 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of DDX46 mRNA | CTD | PMID:24793618 | Ddx46 | Rat | formaldehyde | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of DDX46 mRNA | CTD | PMID:23649840 | Ddx46 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DDX46 mRNA | CTD | PMID:22061828 | Ddx46 | Rat | haloperidol | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Haloperidol] results in increased expression of DDX46 protein | CTD | PMID:34122009 | Ddx46 | Rat | hydralazine | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of DDX46 mRNA | CTD | PMID:17183730 | Ddx46 | Rat | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Arbutin results in increased expression of DDX46 mRNA | CTD | PMID:17103032 | Ddx46 | Rat | ivermectin | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DDX46 protein | CTD | PMID:32959892 | Ddx46 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of DDX46 mRNA | CTD | PMID:30467583 | Ddx46 | Rat | ozone | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DDX46 mRNA more ... | CTD | PMID:32699268 | Ddx46 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of DDX46 mRNA | CTD | PMID:33387578 | Ddx46 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ddx46 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of DDX46 mRNA | CTD | PMID:36331819 | Ddx46 | Rat | propiconazole | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | propiconazole results in decreased expression of DDX46 mRNA | CTD | PMID:22334560 and PMID:23970803 | Ddx46 | Rat | pyrethrins | decreases expression | EXP | | 6480464 | Pyrethrins results in decreased expression of DDX46 protein | CTD | PMID:34896426 | Ddx46 | Rat | resveratrol | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of DDX46 mRNA | CTD | PMID:23557933 | Ddx46 | Rat | SB 431542 | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of DDX46 protein | CTD | PMID:37664457 | Ddx46 | Rat | sodium arsenite | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [DDX46 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | Ddx46 | Rat | succimer | multiple interactions | ISO | Ddx46 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of DDX46 mRNA | CTD | PMID:21641980 | Ddx46 | Rat | tetrachloromethane | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of DDX46 mRNA | CTD | PMID:17484886 | Ddx46 | Rat | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of DDX46 mRNA | CTD | PMID:12734012 | Ddx46 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of DDX46 mRNA | CTD | PMID:34492290 | Ddx46 | Rat | triadimefon | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | triadimefon results in decreased expression of DDX46 mRNA | CTD | PMID:23970803 | Ddx46 | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of DDX46 gene | CTD | PMID:27618143 | Ddx46 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of DDX46 mRNA | CTD | PMID:33387578 | Ddx46 | Rat | trimellitic anhydride | increases expression | ISO | Ddx46 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of DDX46 mRNA | CTD | PMID:19042947 | Ddx46 | Rat | troglitazone | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | troglitazone results in decreased expression of DDX46 mRNA | CTD | PMID:28973697 | Ddx46 | Rat | tungsten | decreases expression | ISO | Ddx46 (Mus musculus) | 6480464 | Tungsten results in decreased expression of DDX46 mRNA | CTD | PMID:30912803 | Ddx46 | Rat | tunicamycin | decreases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of DDX46 mRNA | CTD | PMID:29453283 | Ddx46 | Rat | valproic acid | multiple interactions | ISO | DDX46 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of DDX46 mRNA | CTD | PMID:17183730 | Ddx46 | Rat | valproic acid | affects expression | ISO | Ddx46 (Mus musculus) | 6480464 | Valproic Acid affects the expression of DDX46 mRNA | CTD | PMID:17963808 | Ddx46 | Rat | valproic acid | increases expression | ISO | DDX46 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of DDX46 mRNA | CTD | PMID:23179753 | Ddx46 | Rat | valproic acid | affects expression | ISO | DDX46 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DDX46 mRNA | CTD | PMID:25979313 | |