Agpat4 (1-acylglycerol-3-phosphate O-acyltransferase 4) - Rat Genome Database

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Gene: Agpat4 (1-acylglycerol-3-phosphate O-acyltransferase 4) Rattus norvegicus
Analyze
Symbol: Agpat4
Name: 1-acylglycerol-3-phosphate O-acyltransferase 4
RGD ID: 619916
Description: Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endomembrane system and mitochondrial outer membrane. Orthologous to human AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase delta); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta); 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); 1-AGP acyltransferase 4; 1-AGPAT 4; LPAAT-delta; lysophosphatidic acid acyltransferase delta; MGC93227
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8151,075,081 - 51,181,548 (-)NCBIGRCr8
mRatBN7.2148,525,131 - 48,633,798 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl148,527,323 - 48,633,345 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx149,218,910 - 49,324,839 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,203,981 - 55,309,606 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,294,411 - 49,400,333 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,716,094 - 48,826,292 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,719,633 - 48,825,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0150,929,133 - 51,035,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,986,809 - 43,096,390 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,989,754 - 43,099,335 (-)NCBI
Celera144,317,112 - 44,422,634 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Agpat4Rat3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome  ISOAGPAT4 (Homo sapiens)8554872ClinVar Annotator: match by term: 3-methylglutaconic aciduria with deafness more ...ClinVarPMID:15220921 more ...

1 to 20 of 76 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Agpat4Rat1,2-dimethylhydrazine multiple interactionsISOAgpat4 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AGPAT4 mRNACTDPMID:22206623
Agpat4Rat1,2-dimethylhydrazine decreases expressionISOAgpat4 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of AGPAT4 mRNACTDPMID:22206623
Agpat4Rat17alpha-ethynylestradiol multiple interactionsISOAgpat4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AGPAT4 mRNACTDPMID:17942748
Agpat4Rat17beta-estradiol multiple interactionsISOAGPAT4 (Homo sapiens)6480464[Progesterone co-treated with Estradiol] results in decreased expression of AGPAT4 mRNACTDPMID:17404688
Agpat4Rat2,2',4,4',5,5'-hexachlorobiphenyl decreases expressionISOAgpat4 (Mus musculus)64804642 more ...CTDPMID:20005886
Agpat4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOAgpat4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AGPAT4 mRNACTDPMID:17942748
Agpat4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of AGPAT4 mRNACTDPMID:33387578
Agpat4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of AGPAT4 mRNACTDPMID:34747641
Agpat4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOAgpat4 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of AGPAT4 mRNACTDPMID:28238261
Agpat4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOAgpat4 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of AGPAT4 mRNACTDPMID:21354282
Agpat4Rat2-hydroxypropanoic acid decreases expressionISOAGPAT4 (Homo sapiens)6480464Lactic Acid results in decreased expression of AGPAT4 mRNACTDPMID:30851411
Agpat4Rat2-methylcholine affects expressionISOAGPAT4 (Homo sapiens)6480464beta-methylcholine affects the expression of AGPAT4 mRNACTDPMID:21179406
Agpat4Rat4,4'-sulfonyldiphenol multiple interactionsISOAGPAT4 (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in increased methylation of AGPAT4 geneCTDPMID:31601247
Agpat4Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of AGPAT4 mRNACTDPMID:36041667
Agpat4Rat4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid increases expressionISOAGPAT4 (Homo sapiens)6480464Am 580 results in increased expression of AGPAT4 mRNACTDPMID:16982809
Agpat4Rat4-hydroxyphenyl retinamide decreases expressionISOAgpat4 (Mus musculus)6480464Fenretinide results in decreased expression of AGPAT4 mRNACTDPMID:28973697
Agpat4Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of AGPAT4 mRNACTDPMID:31881176
Agpat4Ratall-trans-retinoic acid decreases expressionISOAGPAT4 (Homo sapiens)6480464Tretinoin results in decreased expression of AGPAT4 mRNACTDPMID:33167477
Agpat4Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of AGPAT4 mRNACTDPMID:16483693
Agpat4Rataristolochic acid A decreases expressionISOAGPAT4 (Homo sapiens)6480464aristolochic acid I results in decreased expression of AGPAT4 mRNACTDPMID:33212167

1 to 20 of 76 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Agpat4RatCDP-diacylglycerol biosynthetic process involved_inIEAUniPathway:UPA005571600115GO_REF:0000041UniProtGO_REF:0000041
Agpat4Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Agpat4Ratphospholipid biosynthetic process involved_inIEAUniProtKB-KW:KW-05941600115GO_REF:0000043UniProtGO_REF:0000043
Agpat4Ratphospholipid metabolic process involved_inIEAUniProtKB:Q8K4X7 and ensembl:ENSMUSP000000245941600115GO_REF:0000107EnsemblGO_REF:0000107
Agpat4Ratphospholipid metabolic process involved_inISOAgpat4 (Mus musculus)1624291MGI:5007015 PMID:26417903RGDPMID:26417903

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Agpat4Ratendomembrane system is_active_inIBAMGI:1336186 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Agpat4Ratendoplasmic reticulum located_inISOAgpat4 (Mus musculus)1624291 PMID:24333445RGDPMID:24333445
Agpat4Ratendoplasmic reticulum located_inIEAUniProtKB:Q8K4X7 and ensembl:ENSMUSP000000245941600115GO_REF:0000107EnsemblGO_REF:0000107
Agpat4Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Agpat4Ratendoplasmic reticulum located_inISSUniProtKB:Q8K4X71600115GO_REF:0000024UniProtGO_REF:0000024
Agpat4Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Agpat4Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Agpat4Ratmitochondrial outer membrane is_active_inIBAMGI:1915512 and PANTHER:PTN0025907911600115GO_REF:0000033GO_CentralGO_REF:0000033
Agpat4Ratmitochondrial outer membrane is_active_inIEAUniProtKB:Q8K4X7 and ensembl:ENSMUSP000000245941600115GO_REF:0000107EnsemblGO_REF:0000107
Agpat4Ratmitochondrial outer membrane is_active_inISOAgpat4 (Mus musculus)1624291 PMID:26417903RGDPMID:26417903
1 to 10 of 10 rows

Molecular Function
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
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Reference
Notes
Source
Original Reference(s)
Agpat4Rat1-acylglycerol-3-phosphate O-acyltransferase activity enablesIEAUniProtKB:Q8K4X7 and ensembl:ENSMUSP000000245941600115GO_REF:0000107EnsemblGO_REF:0000107
Agpat4Rat1-acylglycerol-3-phosphate O-acyltransferase activity enablesIBAMGI:1915512 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Agpat4Rat1-acylglycerol-3-phosphate O-acyltransferase activity enablesIEAEC:2.3.1.511600115GO_REF:0000003UniProtGO_REF:0000003
Agpat4Rat1-acylglycerol-3-phosphate O-acyltransferase activity enablesIEARHEA:197091600115GO_REF:0000116RHEAGO_REF:0000116
Agpat4Rat1-acylglycerol-3-phosphate O-acyltransferase activity enablesISOAgpat4 (Mus musculus)1624291 PMID:24333445RGDPMID:24333445
Agpat4Rat1-acylglycerol-3-phosphate O-acyltransferase activity enablesISSUniProtKB:Q8K4X71600115GO_REF:0000024UniProtGO_REF:0000024
Agpat4Ratacyltransferase activity enablesIEAInterPro:IPR0021231600115GO_REF:0000002InterProGO_REF:0000002
Agpat4Ratacyltransferase activity enablesIEAUniProtKB-KW:KW-00121600115GO_REF:0000043UniProtGO_REF:0000043
Agpat4Ratacyltransferase activity enablesIEAARBA:ARBA000277181600115GO_REF:0000117UniProtGO_REF:0000117
Agpat4Ratlysophosphatidic acid acyltransferase activity enablesISOAgpat4 (Mus musculus)1624291 PMID:26417903RGDPMID:26417903
Agpat4Ratlysophosphatidic acid acyltransferase activity enablesIEAUniProtKB:Q8K4X7 and ensembl:ENSMUSP000000245941600115GO_REF:0000107EnsemblGO_REF:0000107
Agpat4Ratprotein binding enablesISOAGPAT4 (Homo sapiens)1624291UniProtKB:A6NM10-2 more ...RGDPMID:25416956 and PMID:32296183
Agpat4Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 13 of 13 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Agpat4Ratglycerolipid metabolic pathway  IEA 6907045 KEGGrno:00561
Agpat4Ratglycerophospholipid metabolic pathway  IEA 6907045 KEGGrno:00564

1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Information Derived from GenBank Report RGD, Sept. 2003
1 to 9 of 9 rows
PMID:12477932   PMID:15489334   PMID:24333445   PMID:26417903  



Agpat4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8151,075,081 - 51,181,548 (-)NCBIGRCr8
mRatBN7.2148,525,131 - 48,633,798 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl148,527,323 - 48,633,345 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx149,218,910 - 49,324,839 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,203,981 - 55,309,606 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,294,411 - 49,400,333 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,716,094 - 48,826,292 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,719,633 - 48,825,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0150,929,133 - 51,035,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,986,809 - 43,096,390 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,989,754 - 43,099,335 (-)NCBI
Celera144,317,112 - 44,422,634 (-)NCBICelera
Cytogenetic Map1q11NCBI
AGPAT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386161,129,967 - 161,274,061 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6161,129,967 - 161,274,061 (-)EnsemblGRCh38hg38GRCh38
GRCh376161,550,999 - 161,695,093 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366161,471,047 - 161,615,097 (-)NCBINCBI36Build 36hg18NCBI36
Build 346161,527,517 - 161,665,448NCBI
Celera6162,280,457 - 162,424,409 (-)NCBICelera
Cytogenetic Map6q26NCBI
HuRef6159,006,418 - 159,150,408 (-)NCBIHuRef
CHM1_16161,813,702 - 161,957,597 (-)NCBICHM1_1
T2T-CHM13v2.06162,488,365 - 162,632,384 (-)NCBIT2T-CHM13v2.0
Agpat4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,337,372 - 12,438,536 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1712,337,591 - 12,438,532 (+)EnsemblGRCm39 Ensembl
GRCm381712,118,485 - 12,219,649 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,118,704 - 12,219,645 (+)EnsemblGRCm38mm10GRCm38
MGSCv371712,312,150 - 12,412,506 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361711,962,642 - 12,062,998 (+)NCBIMGSCv36mm8
Celera1712,147,922 - 12,252,652 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.33NCBI
Agpat4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,050,619 - 20,132,893 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,050,619 - 20,132,893 (+)NCBIChiLan1.0ChiLan1.0
AGPAT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25181,305,186 - 181,450,074 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16179,210,769 - 179,355,480 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06159,075,360 - 159,219,887 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16164,085,970 - 164,229,696 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6164,092,522 - 164,229,696 (-)Ensemblpanpan1.1panPan2
AGPAT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,709,437 - 49,837,848 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,709,741 - 49,837,091 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,552,643 - 50,680,914 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,894,606 - 50,022,389 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,894,612 - 50,023,044 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,776,903 - 49,904,869 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,647,989 - 49,776,147 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0150,264,213 - 50,392,536 (-)NCBIUU_Cfam_GSD_1.0
Agpat4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,730,179 - 144,826,056 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,981,969 - 12,042,447 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,982,488 - 12,078,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGPAT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl16,772,417 - 6,883,551 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.116,761,734 - 6,883,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218,330,534 - 8,440,346 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGPAT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11388,634,100 - 88,782,371 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1388,640,548 - 88,781,702 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604060,965,050 - 61,111,779 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agpat4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248552,046,014 - 2,161,398 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248552,046,000 - 2,185,729 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Agpat4
537 total Variants

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:55
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000024213
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat

1 to 10 of 45 rows
RH135066  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2148,527,410 - 48,527,604 (+)MAPPERmRatBN7.2
Rnor_6.0148,719,721 - 48,719,914NCBIRnor6.0
Rnor_5.0151,035,217 - 51,035,410UniSTSRnor5.0
RGSC_v3.4142,986,898 - 42,987,091UniSTSRGSC3.4
Celera144,317,201 - 44,317,394UniSTS
RH 3.4 Map1572.9UniSTS
Cytogenetic Map1q11UniSTS
BF415643  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2148,584,748 - 48,584,917 (+)MAPPERmRatBN7.2
Rnor_6.0148,776,921 - 48,777,089NCBIRnor6.0
Rnor_5.0150,978,455 - 50,978,623UniSTSRnor5.0
RGSC_v3.4143,045,145 - 43,045,313UniSTSRGSC3.4
Celera144,374,346 - 44,374,514UniSTS
RH 3.4 Map1586.7UniSTS
Cytogenetic Map1q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024213   ⟹   ENSRNOP00000024213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl148,527,325 - 48,633,238 (-)Ensembl
Rnor_6.0 Ensembl148,719,633 - 48,825,364 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082958   ⟹   ENSRNOP00000069883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl148,527,323 - 48,633,345 (-)Ensembl
Rnor_6.0 Ensembl148,719,942 - 48,797,631 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117069   ⟹   ENSRNOP00000094231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl148,527,325 - 48,633,238 (-)Ensembl
RefSeq Acc Id: NM_133406   ⟹   NP_596897
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8151,075,081 - 51,180,971 (-)NCBI
mRatBN7.2148,527,322 - 48,633,223 (-)NCBI
Rnor_6.0148,719,632 - 48,825,378 (-)NCBI
Rnor_5.0150,929,133 - 51,035,499 (+)NCBI
RGSC_v3.4142,986,809 - 43,096,390 (-)RGD
Celera144,317,112 - 44,422,634 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227856   ⟹   XP_006227918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8151,075,081 - 51,154,717 (-)NCBI
mRatBN7.2148,525,131 - 48,605,505 (-)NCBI
Rnor_6.0148,716,094 - 48,798,471 (-)NCBI
Rnor_5.0150,929,133 - 51,035,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227857   ⟹   XP_006227919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8151,075,081 - 51,181,548 (-)NCBI
mRatBN7.2148,525,131 - 48,633,798 (-)NCBI
Rnor_6.0148,716,094 - 48,826,292 (-)NCBI
Rnor_5.0150,929,133 - 51,035,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063272836   ⟹   XP_063128906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8151,075,081 - 51,148,291 (-)NCBI
1 to 12 of 12 rows
Protein RefSeqs NP_596897 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227918 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227919 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128906 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86992 (Get FASTA)   NCBI Sequence Viewer  
  BAB62290 (Get FASTA)   NCBI Sequence Viewer  
  EDL83076 (Get FASTA)   NCBI Sequence Viewer  
  EDL83077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024213
  ENSRNOP00000024213.2
  ENSRNOP00000069883
GenBank Protein Q924S1 (Get FASTA)   NCBI Sequence Viewer  
1 to 12 of 12 rows
RefSeq Acc Id: NP_596897   ⟸   NM_133406
- UniProtKB: Q924S1 (UniProtKB/Swiss-Prot),   A6KJY8 (UniProtKB/TrEMBL),   A0A8I6ALQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227919   ⟸   XM_006227857
- Peptide Label: isoform X2
- UniProtKB: Q924S1 (UniProtKB/Swiss-Prot),   A6KJY8 (UniProtKB/TrEMBL),   A0A8I6ALQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227918   ⟸   XM_006227856
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JWH4 (UniProtKB/TrEMBL),   A0A8I6ALQ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069883   ⟸   ENSRNOT00000082958
Ensembl Acc Id: ENSRNOP00000024213   ⟸   ENSRNOT00000024213
Phospholipid/glycerol acyltransferase

Name Modeler Protein Id AA Range Protein Structure
AF-Q924S1-F1-model_v2 AlphaFold Q924S1 1-378 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13689623
Promoter ID:EPDNEW_R148
Type:initiation region
Name:Agpat4_1
Description:1-acylglycerol-3-phosphate O-acyltransferase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0148,825,331 - 48,825,391EPDNEW


1 to 35 of 35 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-61557 BioCyc
BioCyc Pathway PWY-5667 [CDP-diacylglycerol biosynthesis I] BioCyc
  PWY-7411 [phosphatidate biosynthesis (yeast)] BioCyc
  PWY-7417 [phospholipid remodeling (phosphatidate, yeast)] BioCyc
  PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY-8053 [anandamide biosynthesis II] BioCyc
  TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-5667 BioCyc
  PWY-7411 BioCyc
  PWY-7417 BioCyc
  PWY-7782 BioCyc
  PWY-8053 BioCyc
  TRIGLSYN-PWY BioCyc
Ensembl Genes ENSRNOG00000017731 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024213 ENTREZGENE
  ENSRNOT00000024213.5 UniProtKB/Swiss-Prot
  ENSRNOT00000082958 ENTREZGENE
IMAGE_CLONE IMAGE:7191675 IMAGE-MGC_LOAD
InterPro Acyltransf_C UniProtKB/Swiss-Prot
  Plipid/glycerol_acylTrfase UniProtKB/Swiss-Prot
KEGG Report rno:170919 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93227 IMAGE-MGC_LOAD
NCBI Gene 170919 ENTREZGENE
PANTHER 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DELTA UniProtKB/Swiss-Prot
  1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED UniProtKB/Swiss-Prot
Pfam Acyltransf_C UniProtKB/Swiss-Prot
  Acyltransferase UniProtKB/Swiss-Prot
PhenoGen Agpat4 PhenoGen
RatGTEx ENSRNOG00000017731 RatGTEx
SMART PlsC UniProtKB/Swiss-Prot
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/Swiss-Prot
UniProt A0A0G2JWH4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALQ9 ENTREZGENE, UniProtKB/TrEMBL
  A6KJY8 ENTREZGENE, UniProtKB/TrEMBL
  PLCD_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 35 of 35 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-13 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4  Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)    1-acylglycerol-3-phosphate O-acyltransferase 4  Name updated 1299863 APPROVED
2004-12-14 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4    1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta)  Name updated 1299863 APPROVED
2002-08-07 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta)      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_function converts lysophosphatidic acid (lpa) into phosphatidic acid by incorporating acyl moiety at the 2 position 724707