Agpat4 (1-acylglycerol-3-phosphate O-acyltransferase 4) - Rat Genome Database

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Gene: Agpat4 (1-acylglycerol-3-phosphate O-acyltransferase 4) Rattus norvegicus
Analyze
Symbol: Agpat4
Name: 1-acylglycerol-3-phosphate O-acyltransferase 4
RGD ID: 619916
Description: Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endomembrane system and mitochondrial outer membrane. Orthologous to human AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase delta); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta); 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); 1-AGP acyltransferase 4; 1-AGPAT 4; LPAAT-delta; lysophosphatidic acid acyltransferase delta; MGC93227
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2148,525,131 - 48,633,798 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl148,527,323 - 48,633,345 (-)Ensembl
Rnor_6.0148,716,094 - 48,826,292 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,719,633 - 48,825,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0150,929,133 - 51,035,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,986,809 - 43,096,390 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,989,754 - 43,099,335 (-)NCBI
Celera144,317,112 - 44,422,634 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:24333445   PMID:26417903  


Genomics

Comparative Map Data
Agpat4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2148,525,131 - 48,633,798 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl148,527,323 - 48,633,345 (-)Ensembl
Rnor_6.0148,716,094 - 48,826,292 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,719,633 - 48,825,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0150,929,133 - 51,035,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,986,809 - 43,096,390 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,989,754 - 43,099,335 (-)NCBI
Celera144,317,112 - 44,422,634 (-)NCBICelera
Cytogenetic Map1q11NCBI
AGPAT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386161,129,967 - 161,274,061 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6161,129,967 - 161,274,061 (-)EnsemblGRCh38hg38GRCh38
GRCh376161,550,999 - 161,695,093 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366161,471,047 - 161,615,097 (-)NCBINCBI36hg18NCBI36
Build 346161,527,517 - 161,665,448NCBI
Celera6162,280,457 - 162,424,409 (-)NCBI
Cytogenetic Map6q26NCBI
HuRef6159,006,418 - 159,150,408 (-)NCBIHuRef
CHM1_16161,813,702 - 161,957,597 (-)NCBICHM1_1
T2T-CHM13v2.06162,488,365 - 162,632,384 (-)NCBI
Agpat4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,337,372 - 12,438,536 (+)NCBIGRCm39mm39
GRCm39 Ensembl1712,337,591 - 12,438,532 (+)Ensembl
GRCm381712,118,485 - 12,219,649 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,118,704 - 12,219,645 (+)EnsemblGRCm38mm10GRCm38
MGSCv371712,312,150 - 12,412,506 (+)NCBIGRCm37mm9NCBIm37
MGSCv361711,962,642 - 12,062,998 (+)NCBImm8
Celera1712,147,922 - 12,252,652 (+)NCBICelera
Cytogenetic Map17A1NCBI
Agpat4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,050,619 - 20,132,893 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,050,619 - 20,132,893 (+)NCBIChiLan1.0ChiLan1.0
AGPAT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16164,085,970 - 164,229,696 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6164,092,522 - 164,229,696 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06159,075,360 - 159,219,887 (-)NCBIMhudiblu_PPA_v0panPan3
AGPAT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,709,437 - 49,837,848 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,709,741 - 49,837,091 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,552,643 - 50,680,914 (-)NCBI
ROS_Cfam_1.0149,894,606 - 50,022,389 (-)NCBI
ROS_Cfam_1.0 Ensembl149,894,612 - 50,023,044 (-)Ensembl
UMICH_Zoey_3.1149,776,903 - 49,904,869 (-)NCBI
UNSW_CanFamBas_1.0149,647,989 - 49,776,147 (-)NCBI
UU_Cfam_GSD_1.0150,264,213 - 50,392,536 (-)NCBI
Agpat4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,730,179 - 144,826,056 (-)NCBI
SpeTri2.0NW_00493648911,982,488 - 12,078,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGPAT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl16,772,506 - 6,883,555 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.116,761,734 - 6,883,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218,330,534 - 8,440,346 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGPAT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11388,634,100 - 88,782,371 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1388,640,548 - 88,781,702 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604060,965,050 - 61,111,779 (-)NCBIVero_WHO_p1.0
Agpat4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248552,046,014 - 2,161,398 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248552,046,000 - 2,185,729 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH135066  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2148,527,410 - 48,527,604 (+)MAPPERmRatBN7.2
Rnor_6.0148,719,721 - 48,719,914NCBIRnor6.0
Rnor_5.0151,035,217 - 51,035,410UniSTSRnor5.0
RGSC_v3.4142,986,898 - 42,987,091UniSTSRGSC3.4
Celera144,317,201 - 44,317,394UniSTS
RH 3.4 Map1572.9UniSTS
Cytogenetic Map1q11UniSTS
BF415643  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2148,584,748 - 48,584,917 (+)MAPPERmRatBN7.2
Rnor_6.0148,776,921 - 48,777,089NCBIRnor6.0
Rnor_5.0150,978,455 - 50,978,623UniSTSRnor5.0
RGSC_v3.4143,045,145 - 43,045,313UniSTSRGSC3.4
Celera144,374,346 - 44,374,514UniSTS
RH 3.4 Map1586.7UniSTS
Cytogenetic Map1q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:55
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000024213
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 33 18 6 12 6 74 32 40 11
Low 10 39 35 7 35 8 11 3 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024213   ⟹   ENSRNOP00000024213
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl148,527,325 - 48,633,238 (-)Ensembl
Rnor_6.0 Ensembl148,719,633 - 48,825,364 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082958   ⟹   ENSRNOP00000069883
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl148,527,323 - 48,633,345 (-)Ensembl
Rnor_6.0 Ensembl148,719,942 - 48,797,631 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117069   ⟹   ENSRNOP00000094231
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl148,527,325 - 48,633,238 (-)Ensembl
RefSeq Acc Id: NM_133406   ⟹   NP_596897
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2148,527,322 - 48,633,223 (-)NCBI
Rnor_6.0148,719,632 - 48,825,378 (-)NCBI
Rnor_5.0150,929,133 - 51,035,499 (+)NCBI
RGSC_v3.4142,986,809 - 43,096,390 (-)RGD
Celera144,317,112 - 44,422,634 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227856   ⟹   XP_006227918
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2148,525,131 - 48,605,505 (-)NCBI
Rnor_6.0148,716,094 - 48,798,471 (-)NCBI
Rnor_5.0150,929,133 - 51,035,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227857   ⟹   XP_006227919
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2148,525,131 - 48,633,798 (-)NCBI
Rnor_6.0148,716,094 - 48,826,292 (-)NCBI
Rnor_5.0150,929,133 - 51,035,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085185   ⟹   XP_038941113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2148,525,131 - 48,605,498 (-)NCBI
RefSeq Acc Id: XM_039085215   ⟹   XP_038941143
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2148,525,131 - 48,633,415 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_596897   ⟸   NM_133406
- UniProtKB: Q924S1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006227919   ⟸   XM_006227857
- Peptide Label: isoform X2
- UniProtKB: Q924S1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006227918   ⟸   XM_006227856
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JWH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069883   ⟸   ENSRNOT00000082958
RefSeq Acc Id: ENSRNOP00000024213   ⟸   ENSRNOT00000024213
RefSeq Acc Id: XP_038941143   ⟸   XM_039085215
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941113   ⟸   XM_039085185
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000094231   ⟸   ENSRNOT00000117069
Protein Domains
PlsC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q924S1-F1-model_v2 AlphaFold Q924S1 1-378 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689623
Promoter ID:EPDNEW_R148
Type:initiation region
Name:Agpat4_1
Description:1-acylglycerol-3-phosphate O-acyltransferase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0148,825,331 - 48,825,391EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619916 AgrOrtholog
BioCyc Gene G2FUF-61557 BioCyc
BioCyc Pathway PWY-5667 [CDP-diacylglycerol biosynthesis I] BioCyc
  PWY-7411 [phosphatidate biosynthesis (yeast)] BioCyc
  PWY-7417 [phospholipid remodeling (phosphatidate, yeast)] BioCyc
  PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY-8053 [anandamide biosynthesis II] BioCyc
  TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000017731 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024213 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000069883 ENTREZGENE
  ENSRNOP00000069883.1 UniProtKB/TrEMBL
  ENSRNOP00000094231.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024213 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000082958 ENTREZGENE
  ENSRNOT00000082958.2 UniProtKB/TrEMBL
  ENSRNOT00000117069.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7191675 IMAGE-MGC_LOAD
InterPro Acyltransf_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plipid/glycerol_acylTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:170919 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93227 IMAGE-MGC_LOAD
NCBI Gene 170919 ENTREZGENE
Pfam Acyltransf_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Agpat4 PhenoGen
SMART PlsC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JWH4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALQ9_RAT UniProtKB/TrEMBL
  PLCD_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-13 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4  Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)    1-acylglycerol-3-phosphate O-acyltransferase 4  Name updated 1299863 APPROVED
2004-12-14 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 4    1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta)  Name updated 1299863 APPROVED
2002-08-07 Agpat4  1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function converts lysophosphatidic acid (lpa) into phosphatidic acid by incorporating acyl moiety at the 2 position 724707