Ppp4r1 (protein phosphatase 4, regulatory subunit 1)

Gene: Ppp4r1 (protein phosphatase 4, regulatory subunit 1) Rattus norvegicus

Analyze

Symbol:

Ppp4r1

Name:

protein phosphatase 4, regulatory subunit 1

RGD ID:

619798

Description:

Predicted to enable protein phosphatase regulator activity. Predicted to be active in cytoplasm. Orthologous to human PPP4R1 (protein phosphatase 4 regulatory subunit 1); INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Pp4r1; serine/threonine-protein phosphatase 4 regulatory subunit 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	112,836,950 - 112,897,490 (+)	NCBI		GRCr8
mRatBN7.2	9	105,391,271 - 105,450,626 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	105,391,412 - 105,450,633 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	113,798,599 - 113,859,120 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	118,905,997 - 118,969,026 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	117,264,559 - 117,324,969 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	113,515,312 - 113,573,308 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	113,534,326 - 113,573,307 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	113,066,545 - 113,105,528 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	104,572,704 - 104,611,601 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	104,782,185 - 104,821,080 (+)	NCBI
Celera	9	102,770,161 - 102,827,110 (+)	NCBI		Celera
Cytogenetic Map	9	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 18p deletion syndrome (ISO)

dystonia (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

3-chloropropane-1,2-diol (EXP)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amitrole (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

atrazine (ISO)

auramine O (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP,ISO)

caffeine (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

decabromodiphenyl ether (ISO)

diethylstilbestrol (ISO)

estriol (ISO)

ethanol (ISO)

flavonoids (EXP)

folic acid (ISO)

ivermectin (ISO)

kojic acid (ISO)

lead(0) (ISO)

methimazole (EXP)

N-nitrosodiethylamine (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

propiconazole (EXP)

Soman (EXP)

sulfadimethoxine (EXP)

tamoxifen (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IBA)

Molecular Function

protein binding (ISO)

protein phosphatase regulator activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8.	Cloning and characterization of a novel subunit of protein serine/threonine phosphatase 4 from mesangial cells.	Wada T, etal., J Am Soc Nephrol 2001 Dec;12(12):2601-8.

Additional References at PubMed

PMID:15489334

Genomics

Comparative Map Data

Ppp4r1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	112,836,950 - 112,897,490 (+)	NCBI		GRCr8
mRatBN7.2	9	105,391,271 - 105,450,626 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	105,391,412 - 105,450,633 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	113,798,599 - 113,859,120 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	118,905,997 - 118,969,026 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	117,264,559 - 117,324,969 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	113,515,312 - 113,573,308 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	113,534,326 - 113,573,307 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	113,066,545 - 113,105,528 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	104,572,704 - 104,611,601 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	104,782,185 - 104,821,080 (+)	NCBI
Celera	9	102,770,161 - 102,827,110 (+)	NCBI		Celera
Cytogenetic Map	9	q37	NCBI

PPP4R1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	9,546,794 - 9,617,199 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	9,546,791 - 9,615,240 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	9,546,792 - 9,614,557 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	9,536,792 - 9,604,600 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	9,536,841 - 9,604,567	NCBI
Celera	18	9,431,022 - 9,498,791 (-)	NCBI		Celera
Cytogenetic Map	18	p11.22	NCBI
HuRef	18	9,509,276 - 9,576,873 (-)	NCBI		HuRef
CHM1_1	18	9,546,520 - 9,614,326 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	9,710,190 - 9,781,391 (-)	NCBI		T2T-CHM13v2.0

Ppp4r1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	66,089,253 - 66,148,921 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	66,089,568 - 66,148,921 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	65,782,543 - 65,841,926 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	65,782,573 - 65,841,926 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	66,132,695 - 66,191,266 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	65,719,688 - 65,741,389 (+)	NCBI		MGSCv36	mm8
Celera	17	70,106,657 - 70,145,143 (+)	NCBI		Celera
Cytogenetic Map	17	E1.1	NCBI
cM Map	17	35.26	NCBI

Ppp4r1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	2,515,057 - 2,568,860 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	2,529,335 - 2,568,621 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPP4R1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	28,835,624 - 28,906,818 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	14,528,218 - 14,599,412 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	4,671,010 - 4,742,301 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	6,957,754 - 7,022,996 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	6,974,934 - 7,022,996 (+)	Ensembl	panpan1.1		panPan2

PPP4R1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	75,524,483 - 75,582,850 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	75,525,249 - 75,583,553 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	74,920,570 - 74,981,437 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	75,583,143 - 75,644,350 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	75,583,161 - 75,644,272 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	75,281,276 - 75,342,393 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	75,298,587 - 75,360,124 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	75,608,737 - 75,670,013 (-)	NCBI		UU_Cfam_GSD_1.0

Ppp4r1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	2,547,917 - 2,597,873 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936626	1,790,837 - 1,826,245 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936626	1,776,194 - 1,826,243 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP4R1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	98,462,855 - 98,544,477 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	98,462,833 - 98,539,649 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PPP4R1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	68,417,293 - 68,488,683 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	68,418,292 - 68,488,176 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	43,369,057 - 43,441,048 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp4r1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	18,150,135 - 18,206,898 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	18,150,135 - 18,206,835 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ppp4r1
228 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	511
Count of miRNA genes:	260
Interacting mature miRNAs:	316
Transcripts:	ENSRNOT00000066793
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat

Markers in Region

RH132764

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	105,450,790 - 105,450,983 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	113,573,473 - 113,573,665	NCBI	Rnor6.0
Rnor_5.0	9	113,105,693 - 113,105,885	UniSTS	Rnor5.0
RGSC_v3.4	9	104,611,766 - 104,611,958	UniSTS	RGSC3.4
Celera	9	102,827,275 - 102,827,467	UniSTS
Cytogenetic Map	9	q37	UniSTS

RH139106

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	105,450,826 - 105,450,983 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	113,573,509 - 113,573,665	NCBI	Rnor6.0
Rnor_5.0	9	113,105,729 - 113,105,885	UniSTS	Rnor5.0
RGSC_v3.4	9	104,611,802 - 104,611,958	UniSTS	RGSC3.4
Celera	9	102,827,311 - 102,827,467	UniSTS
Cytogenetic Map	9	q37	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	41	55	39	19	39	3	3	74	35	41	11	3
Low		2	2	2		2	5	8					5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_080907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010054562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF332004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000066793 ⟹ ENSRNOP00000061977

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	105,391,938 - 105,450,625 (+)	Ensembl
Rnor_6.0 Ensembl	9	113,534,326 - 113,573,307 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104139 ⟹ ENSRNOP00000090902

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	105,391,412 - 105,450,633 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111258 ⟹ ENSRNOP00000097964

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	105,408,035 - 105,450,633 (+)	Ensembl

RefSeq Acc Id:

NM_080907 ⟹ NP_543183

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,806 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,391,938 - 105,450,626 (+)	NCBI
Rnor_6.0	9	113,515,312 - 113,573,308 (+)	NCBI
Rnor_5.0	9	113,066,545 - 113,105,528 (+)	NCBI
RGSC_v3.4	9	104,572,704 - 104,611,601 (+)	RGD
Celera	9	102,770,161 - 102,827,110 (+)	RGD

Sequence:

show sequence

CGCCGGCCCGCGCGCGCCCACCGGCTCCCGGCTCGCGCGGCTCGCGGAGCGGGATCCCGGGAGA
CGAGGAGGCGGGGGCGAGCACAAGATGGCGGACCTCTCGCTGCTCCAGGAGGACCTGCCGGAGG
ACGCGGACGGACTTGGTGTGGATGACTACAGCTCAGAGTCTGATGTGATTATTATACCTTCAGC
CCTGGACTTCGTCTCACAAGATGAAATGTTGACACCCTTGGGGAGGCTGGACAAGTATGCTGCA
AGTGAGAACGTCTTTAACAGACAAATGGTGGCCCGGAGTTTGCTGGATACTCTGAGGGAAGTCT
GTGGTGAGGAGAGAGACTGCATTGCTGTCTTGGAAAGGATCAGCCGATTGGCTGATGACTCAGA
ACCAACCGTGAGAGCCGAGCTGATGGAACAGGTGCCGCACATCGCACTGTTTTGTCAAGAGAAC
CGACCTTCCATACCATATGCCTTTTCCAAGTACTTACTGCCAATCGTGGTTAGATACCTTGCAG
ACCAGAATAACCAGGTGAGGAAAACCAGCCAGGCAGCTTTGCTGGCTCTGCTGGAGCAGGAGCT
GATTGAGCGACTCGATGTGGAGACCAAGGTGTGCCCCGTCCTCATAGACTTGACTGCCCCAGAC
AGCAATGACGATGTGAAGACAGAGGCCGTGGCTATAATGTGCAAGATGGCCCCCATGGTTGGGA
AAGATATTACAGAGCGTCTCATCCTCCCTAGGTTTTGTGAGATGTGCTGTGACTGTAGAATGTT
TCACGTCCGAAAGGTCTGTGCTGCCAATTTTGGAGACATTTGCAGCGTAGTTGGCCAGCAAGCT
ACAGAAGAAATGCTGCTGCCCAGGTTCTTCCAGCTGTGTTCTGACAATGTGTGGGGCGTCCGGA
AGGCCTGTGCTGAGTGCTTCATGGCCGTCTCCTGCGCGACATGCCAAGAAATCCGACGGACAAA
GTTGTCAGCACTGTTTATTAACTTGATCAGTGATCCTTCACGTTGGGTTCGCCAAGCAGCCTTT
CAGTCCCTGGGGCCTTTCATATCCACATTTGCTAATCCATCAAGCTCGGGCCAGTGCTTCAAAG
ATGAGAGCAAAAGCTCAGAAGACAAAGACAGGATCAGAGACGATGGTGTTGTACAAGAAGAGCA
GAGCAGGCCAGAGGACGCACCTTCAGACCTCAGTGCCCCTCACTCCAGTGCCAGGCTGGACGGC
ACACTTGAAGGCTGTGCTGCCGAGACGCCTGGGGACTCTGCAGGTGACATGCGTGTTCCAGCGG
ACAGCTCCTTACTCTGTACTTTGTCCTCAGAGTCTCCTCAGGAAGCAGCTAGTGACGCTGAGAG
TGGTAAAAAGCACGATAACAACAGCAAGTCTGCGTCCCGGCCAGACGTTGGCACCAGCTCCCCA
GAGCCCACTCCCTTAGATCAGGAAATGTTCAACTCCTTCCATTTCTGGAGGACTCCTCTACCCC
AGATAGATCTTGATAAAGAGCTCCAACAGGACCCTGGGGAGAGGCCCAGCCCAGAGAGAACAGG
AGATGCACCTGCAGCCCCTGTACCAGGTTCTCCCAGTATCACCATGGCTACCCGGAAGGAACTA
GAAGAAATGATAGAAAACCTAGAGCCGCACATGGATGACCCGGATGTTAAAGCCCAGGTGGAAG
TGCTGTCGGCCGCCCTGCGCGCTTCTACCCTGGATGCTCACGACGAGGCTGGCGGTGCAGAGCA
GCGGAGTGAGCTGCAGGACGACGCAGTGGGTGCCGGCGGCGAGCTTCCAAACTGTAGCATCAGC
GAAGACACTTCTGAGCCTCTGGTCATCGCTGCTGAGGAGAATATGGAGGCCACTCCTGACTATA
TCCATGGAGGTGCGGATGTAGGCCCCGGTGGCGGTGGTGGCTTCAGCCCGGATGAAGAGAGGAG
ACCCAAAGTCCAGGATGTCGTACCACAAGCGTTACTAGACCAGTACCTGTCAATGACCGACCCT
TCTCGAGCACAGACAGTCGACACCGAGATCGCTAAGCACTGTGCATACAGTCTGCCGGGTGTGG
CTCTGACCCTTGGCAGACAGAACTGGCACTGCTTGAGAGAGACTTACGAGACCCTAGCGTCAGA
CATGCAGTGGAAAGTTCGAAGAACTCTGGCCTTCTCCATCCATGAGCTCGCGGTGATTCTCGGG
GACCAGCTGACAGCAGCAGACCTGGTTCCGATTTTTAATGGGTTTTTAAAAGATCTTGACGAAG
TCAGGATAGGTGTTCTCAAACACTTGCATGACTTTCTGAAGCTTCTTCATATTGATAAAAGAAG
AGAGTACCTTTATCAACTCCAGGAGTTTTTGGTGACAGACAACAGTAGAAATTGGCGGTTTCGA
GCTGAACTGGCAGAACAGCTGATTTTACTTCTAGAATTATATAGTCCCAGAGATGTTTATGATT
ACTTACGTCCCATTGCTCTGAATCTGTGTGCAGACAAAGTTTCTTCAGTCCGTTGGATTTCCTA
CAAGTTGGTCAGTGAGATGGTGAAGAAGCTACACATGGCGACGCCGCCAACGTTCGGAGTCGAG
CTCATCAATGAGCTGGTGGAGAACTTCGGCAGGTGTCCAAAGTGGTCGGGCCGGCAGGCCTTCG
TCTTCGTGTGCCAGACTGTCATTGAGGACGACTGCCTCCCCATGGACCAGTTTGCTGTGCACCT
GATGCCACATTTGCTGACCTTGGCAAATGACAGGGTTCCCAACGTTAGAGTGCTGCTTGCAAAA
ACCCTTCGACAGACTCTACTAGAGAAAGAATACTTCTTAGCCTCTGCCAGCTGTCATCAGGAGG
CCGTGGAGCAGACAATCATGGCCCTTCAGATGGATCGAGACAGTGACGTCAAGTACTTTGCAAG
CATCCACCCGTCCAGTACCAAACTCTCTGAAGACGCAATGAGTACAGCTTCCTCCACCTACTGA
CCCCTGACCCACGGTGTCCTTCCTGCATCCGCGAGAGCCTGGCCTCAGCCGCCTGCGCCACTCG
GGACAGCTGTGGTGGTGGGGCCTCCCTCCTGCCAGCTCATTCGCAGGTGCAAGTTGCCTACTCC
CATACCAGTGGTTTTAAGAGTCAAGAGAAAGTACAGTAAACACTATTATCTTATCTTGACTTAG
GGAAAGTAAACTCTCAGAGGATTATAATTGTCACCAAAGCCTTAACTCATTACTTCCTCTTCCT
GACTGAATGACTTGAATTGGCAGAGCATTTTCCCTTCGGGAAGGAGGAGGTTCCCAGAGACCTG
CGCTGCTTTCTCCTGGTTTTATTTAACGCTGGTAAATGGCATTCTTACCGCCGGAAGGTGGACA
CGCACCGGACAGGGAGGCCTGGGTATTAGCCCAAGCACTTGTCCCAGGTGCGAGTCTGCTCGGC
TCCTGGGCTGCCCTGCCCAGCCCTAAGTGTGAATAGTTCTTGGCGTGTATAAATGACAGGAGTT
TTTCCTCTCCTAAGGGCTTGATGTTAACACTAAGTAGAATCTGATTTTGACTCCTAATGCAGCA
CATTGCTGTACACATTTACAGAATGTTTGCAGACTCTCTCCCGACTCTTTTCATGCTGGTCATG
ACGTGAAGGGGACTTCTCAGCAGATATTGTGTCAGGTGTTCTTAACTTGATCATGGTCAGCTCT
GAGGTGCGACTTTCCTTCCCATGCTGCACACCCCTGTGGCCACGCTGGGGCATGCAGCCTTAAT
CATGCTGTTAGAACTGTTGTGGTACAAATTCCAAATAAAATTTATTAATAGGAAAAAAAAAAAA
AAAAAA

hide sequence

RefSeq Acc Id:

XM_039082977 ⟹ XP_038938905

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,852,947 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,408,011 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082978 ⟹ XP_038938906

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,869 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,391,956 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082979 ⟹ XP_038938907

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,839,134 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,392,266 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082980 ⟹ XP_038938908

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,758 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,391,884 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082981 ⟹ XP_038938909

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,852,946 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,408,010 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082982 ⟹ XP_038938910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,836,950 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,391,271 - 105,450,626 (+)	NCBI

RefSeq Acc Id:

XM_039082983 ⟹ XP_038938911

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,852,953 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,408,014 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082984 ⟹ XP_038938912

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,388 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,391,522 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_039082985 ⟹ XP_038938913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,852,949 - 112,897,490 (+)	NCBI
mRatBN7.2	9	105,408,012 - 105,449,805 (+)	NCBI

RefSeq Acc Id:

XM_063266612 ⟹ XP_063122682

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,557 - 112,879,255 (+)	NCBI

RefSeq Acc Id:

XR_010054561

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,555 - 112,889,173 (+)	NCBI

RefSeq Acc Id:

XR_010054562

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	112,838,556 - 112,887,500 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_543183	(Get FASTA)	NCBI Sequence Viewer
	XP_038938905	(Get FASTA)	NCBI Sequence Viewer
	XP_038938906	(Get FASTA)	NCBI Sequence Viewer
	XP_038938907	(Get FASTA)	NCBI Sequence Viewer
	XP_038938908	(Get FASTA)	NCBI Sequence Viewer
	XP_038938909	(Get FASTA)	NCBI Sequence Viewer
	XP_038938910	(Get FASTA)	NCBI Sequence Viewer
	XP_038938911	(Get FASTA)	NCBI Sequence Viewer
	XP_038938912	(Get FASTA)	NCBI Sequence Viewer
	XP_038938913	(Get FASTA)	NCBI Sequence Viewer
	XP_063122682	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH61726	(Get FASTA)	NCBI Sequence Viewer
	AAL37490	(Get FASTA)	NCBI Sequence Viewer
	EDL91809	(Get FASTA)	NCBI Sequence Viewer
	EDL91810	(Get FASTA)	NCBI Sequence Viewer
	EDL91811	(Get FASTA)	NCBI Sequence Viewer
	EDL91812	(Get FASTA)	NCBI Sequence Viewer
	EDL91813	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061977
	ENSRNOP00000061977.3
	ENSRNOP00000090902
	ENSRNOP00000090902.1
	ENSRNOP00000097964
	ENSRNOP00000097964.1
	ENSRNOP00055026418
GenBank Protein	Q8VI02	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_543183 ⟸ NM_080907

- UniProtKB:

Q8VI02 (UniProtKB/Swiss-Prot), F1LRK9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADLSLLQEDLPEDADGLGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENVFNRQ
MVARSLLDTLREVCGEERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAF
SKYLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERLDVETKVCPVLIDLTAPDSNDDVKTE
AVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPR
FFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFIS
TFANPSSSGQCFKDESKSSEDKDRIRDDGVVQEEQSRPEDAPSDLSAPHSSARLDGTLEGCAAE
TPGDSAGDMRVPADSSLLCTLSSESPQEAASDAESGKKHDNNSKSASRPDVGTSSPEPTPLDQE
MFNSFHFWRTPLPQIDLDKELQQDPGERPSPERTGDAPAAPVPGSPSITMATRKELEEMIENLE
PHMDDPDVKAQVEVLSAALRASTLDAHDEAGGAEQRSELQDDAVGAGGELPNCSISEDTSEPLV
IAAEENMEATPDYIHGGADVGPGGGGGFSPDEERRPKVQDVVPQALLDQYLSMTDPSRAQTVDT
EIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADL
VPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLI
LLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHMATPPTFGVELINELVEN
FGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLE
KEYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPSSTKLSEDAMSTASSTY

hide sequence

RefSeq Acc Id:

ENSRNOP00000061977 ⟸ ENSRNOT00000066793

RefSeq Acc Id:	XP_038938910 ⟸ XM_039082982
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6ACS7 (UniProtKB/TrEMBL), A6JRC6 (UniProtKB/TrEMBL), A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938912 ⟸ XM_039082984
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6ACS7 (UniProtKB/TrEMBL), A6JRC6 (UniProtKB/TrEMBL), A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938908 ⟸ XM_039082980
- Peptide Label:	isoform X4
- UniProtKB:	F1LRK9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938906 ⟸ XM_039082978
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938907 ⟸ XM_039082979
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938909 ⟸ XM_039082981
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938905 ⟸ XM_039082977
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938913 ⟸ XM_039082985
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6ACS7 (UniProtKB/TrEMBL), A6JRC6 (UniProtKB/TrEMBL), A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938911 ⟸ XM_039082983
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6ACS7 (UniProtKB/TrEMBL), A6JRC6 (UniProtKB/TrEMBL), A0A8I6AX20 (UniProtKB/TrEMBL), A6JRC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000097964 ⟸ ENSRNOT00000111258

RefSeq Acc Id:

ENSRNOP00000090902 ⟸ ENSRNOT00000104139

RefSeq Acc Id:	XP_063122682 ⟸ XM_063266612
- Peptide Label:	isoform X7

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8VI02-F1-model_v2	AlphaFold	Q8VI02	1-951	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619798	AgrOrtholog
BioCyc Gene	G2FUF-26483	BioCyc
Ensembl Genes	ENSRNOG00000013733	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00055019100	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000066793	ENTREZGENE
	ENSRNOT00000066793.4	UniProtKB/TrEMBL
	ENSRNOT00000104139.1	UniProtKB/TrEMBL
	ENSRNOT00000111258.1	UniProtKB/TrEMBL
	ENSRNOT00055032616	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5598703	IMAGE-MGC_LOAD
InterPro	ARM-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HEAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HEAT_type_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:140943	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72329	IMAGE-MGC_LOAD
NCBI Gene	140943	ENTREZGENE
PANTHER	PTHR10648:SF8	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HEAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ppp4r1	PhenoGen
PROSITE	HEAT_REPEAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013733	RatGTEx
	ENSRNOG00055019100	RatGTEx
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6ACS7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AX20	ENTREZGENE, UniProtKB/TrEMBL
	A6JRC4	ENTREZGENE, UniProtKB/TrEMBL
	A6JRC5_RAT	UniProtKB/TrEMBL
	A6JRC6	ENTREZGENE, UniProtKB/TrEMBL
	A6JRC7_RAT	UniProtKB/TrEMBL
	A6JRC8_RAT	UniProtKB/TrEMBL
	F1LRK9	ENTREZGENE, UniProtKB/TrEMBL
	PP4R1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-02-26	Ppp4r1	protein phosphatase 4, regulatory subunit 1			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Ppp4r1	protein phosphatase 4, regulatory subunit 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar