Tmod2 (tropomodulin 2) - Rat Genome Database

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Gene: Tmod2 (tropomodulin 2) Rattus norvegicus
Analyze
Symbol: Tmod2
Name: tropomodulin 2
RGD ID: 61948
Description: Enables actin binding activity and tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Predicted to act upstream of or within learning or memory; neuron-neuron synaptic transmission; and positive regulation of G protein-coupled receptor signaling pathway. Located in growth cone. Orthologous to human TMOD2 (tropomodulin 2); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: N-Tmod; neuronal tropomodulin; tropomodulin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8885,197,222 - 85,250,627 (-)NCBIGRCr8
mRatBN7.2876,316,736 - 76,366,003 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl876,325,667 - 76,365,720 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx881,833,194 - 81,859,701 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0880,098,086 - 80,124,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0877,932,534 - 77,959,043 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,505,947 - 82,547,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,506,934 - 82,533,689 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0882,108,631 - 82,148,859 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,392,806 - 80,419,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,411,859 - 80,438,369 (-)NCBI
Celera876,115,302 - 76,142,235 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmod2RatBloom syndrome  ISOTMOD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:28492532
Tmod2Ratcolorectal cancer  ISOTMOD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532
Tmod2Ratdevelopmental and epileptic encephalopathy 13  ISOTMOD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 13ClinVar 
Tmod2Ratparaplegia  ISOTMOD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:21620353 more ...

1 to 20 of 93 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmod2Rat(+)-lariciresinol decreases expressionISOTMOD2 (Homo sapiens)6480464lariciresinol results in decreased expression of TMOD2 proteinCTDPMID:27417256
Tmod2Rat(-)-lariciresinol decreases expressionISOTMOD2 (Homo sapiens)6480464lariciresinol results in decreased expression of TMOD2 proteinCTDPMID:27417256
Tmod2Rat1,2-dichloroethane decreases expressionISOTmod2 (Mus musculus)6480464ethylene dichloride results in decreased expression of TMOD2 mRNACTDPMID:28960355
Tmod2Rat1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expressionEXP 6480464chlorcyclizine results in decreased expression of TMOD2 mRNACTDPMID:21058326
Tmod2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of TMOD2 mRNACTDPMID:29097150
Tmod2Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of TMOD2 mRNACTDPMID:20068009
Tmod2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTmod2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TMOD2 mRNACTDPMID:21570461
Tmod2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of TMOD2 mRNACTDPMID:33387578
Tmod2Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Tmod2Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expressionISOTmod2 (Mus musculus)64804642 more ...CTDPMID:18550172
Tmod2Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expressionISOTmod2 (Mus musculus)64804642 more ...CTDPMID:18550172
Tmod2Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOTmod2 (Mus musculus)6480464tetrabromobisphenol A results in decreased expression of TMOD2 mRNACTDPMID:25172293
Tmod2Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOTMOD2 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TMOD2 mRNACTDPMID:28628672
Tmod2Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of TMOD2 mRNACTDPMID:30047161
Tmod2Ratacrylamide decreases expressionISOTMOD2 (Homo sapiens)6480464Acrylamide results in decreased expression of TMOD2 mRNACTDPMID:32763439
Tmod2Ratactinomycin D increases expressionISOTMOD2 (Homo sapiens)6480464Dactinomycin results in increased expression of TMOD2 mRNACTDPMID:38460933
Tmod2Ratactinomycin D multiple interactionsISOTMOD2 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased expression of TMOD2 mRNACTDPMID:38460933
Tmod2Rataflatoxin B1 decreases methylationISOTMOD2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of TMOD2 geneCTDPMID:27153756
Tmod2Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of TMOD2 mRNACTDPMID:16483693
Tmod2Ratbenzo[a]pyrene increases expressionISOTMOD2 (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of TMOD2 mRNACTDPMID:22316170

1 to 20 of 93 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmod2Ratactin filament organization involved_inIBAMGI:2135672 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmod2Ratactin filament organization  TAS 61770 RGD 
Tmod2Ratlearning or memory acts_upstream_of_or_withinISOTmod2 (Mus musculus)1624291MGI:2664502 PMID:12799133RGDPMID:12799133
Tmod2Ratmuscle contraction involved_inIBAMGI:98775 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmod2Ratmyofibril assembly involved_inIBAMGI:2135672 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmod2Ratneuron-neuron synaptic transmission acts_upstream_of_or_withinISOTmod2 (Mus musculus)1624291MGI:2664500 more ...RGDPMID:12799133
Tmod2Ratpointed-end actin filament capping involved_inIEAInterPro:IPR0049341600115GO_REF:0000002InterProGO_REF:0000002
Tmod2Ratpositive regulation of G protein-coupled receptor signaling pathway acts_upstream_of_or_withinISOTmod2 (Mus musculus)1624291MGI:2664500 PMID:12799133RGDPMID:12799133

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmod2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Tmod2Ratcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044
Tmod2Ratcytoskeleton is_active_inIBAMGI:1355285 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmod2Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Tmod2Ratgrowth cone  IDA 61770 RGD 
Tmod2Ratmyofibril is_active_inIBAFB:FBgn0082582 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmod2Ratstriated muscle thin filament is_active_inIBAMGI:1355285 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmod2Ratsynapse located_inIEAGO:00072701600115GO_REF:0000108GOCGO_REF:0000108

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmod2Ratactin binding enablesIEAUniProtKB-KW:KW-00091600115GO_REF:0000043UniProtGO_REF:0000043
Tmod2Ratactin binding  IDA 61770 RGD 
Tmod2Ratprotein binding enablesISOTMOD2 (Homo sapiens)1624291UniProtKB:A0A6Q8PF08 and PMID:32814053RGDPMID:32814053
Tmod2Rattropomyosin binding enablesIEAInterPro:IPR0049341600115GO_REF:0000002InterProGO_REF:0000002
Tmod2Rattropomyosin binding  IDA 61770 RGD 
Tmod2Rattropomyosin binding enablesIBAMGI:1355285 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
7. N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. Watakabe A, etal., J Cell Sci 1996 Sep;109 ( Pt 9)(2):2299-310.
PMID:12799133   PMID:20131911   PMID:22871113   PMID:24625528   PMID:27126680   PMID:29476059   PMID:30301754  



Tmod2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8885,197,222 - 85,250,627 (-)NCBIGRCr8
mRatBN7.2876,316,736 - 76,366,003 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl876,325,667 - 76,365,720 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx881,833,194 - 81,859,701 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0880,098,086 - 80,124,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0877,932,534 - 77,959,043 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,505,947 - 82,547,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,506,934 - 82,533,689 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0882,108,631 - 82,148,859 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,392,806 - 80,419,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,411,859 - 80,438,369 (-)NCBI
Celera876,115,302 - 76,142,235 (-)NCBICelera
Cytogenetic Map8q24NCBI
TMOD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381551,751,597 - 51,816,363 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1551,751,597 - 51,816,363 (+)EnsemblGRCh38hg38GRCh38
GRCh371552,043,794 - 52,108,560 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361549,831,102 - 49,889,635 (+)NCBINCBI36Build 36hg18NCBI36
Build 341549,831,101 - 49,889,634NCBI
Celera1528,937,177 - 29,001,954 (+)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1528,874,266 - 28,939,046 (+)NCBIHuRef
CHM1_11552,161,794 - 52,226,629 (+)NCBICHM1_1
T2T-CHM13v2.01549,559,103 - 49,623,854 (+)NCBIT2T-CHM13v2.0
Tmod2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39975,472,903 - 75,518,620 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl975,472,903 - 75,518,607 (-)EnsemblGRCm39 Ensembl
GRCm38975,565,621 - 75,611,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl975,565,621 - 75,611,325 (-)EnsemblGRCm38mm10GRCm38
MGSCv37975,413,428 - 75,459,132 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36975,351,530 - 75,397,234 (-)NCBIMGSCv36mm8
Celera972,726,546 - 72,775,171 (-)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.31NCBI
Tmod2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554092,808,543 - 2,842,844 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554092,801,173 - 2,842,717 (-)NCBIChiLan1.0ChiLan1.0
TMOD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21640,985,905 - 41,053,274 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11545,166,348 - 45,233,756 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01530,690,641 - 30,757,960 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11549,035,929 - 49,087,467 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1549,035,929 - 49,079,570 (+)Ensemblpanpan1.1panPan2
TMOD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13017,425,216 - 17,501,484 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3017,455,987 - 17,592,580 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3017,351,455 - 17,420,147 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03017,571,419 - 17,646,819 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3017,588,331 - 17,740,756 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13017,492,670 - 17,561,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03017,611,072 - 17,686,398 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03017,717,590 - 17,785,938 (+)NCBIUU_Cfam_GSD_1.0
Tmod2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864095,742,038 - 95,794,177 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647113,602,732 - 13,729,228 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647113,602,769 - 13,636,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMOD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1119,956,588 - 120,009,372 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11119,956,583 - 120,009,372 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21133,216,996 - 133,269,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMOD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12631,560,112 - 31,624,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2631,568,024 - 31,624,905 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048109,589,912 - 109,655,378 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmod2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247318,583,352 - 8,605,826 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247318,575,955 - 8,612,553 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Tmod2
202 total Variants

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:27
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000014124
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 57 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat

1 to 10 of 57 rows
AW535177  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2876,325,756 - 76,325,912 (+)MAPPERmRatBN7.2
Rnor_6.0882,507,145 - 82,507,300NCBIRnor6.0
Rnor_5.0882,109,829 - 82,109,984UniSTSRnor5.0
RGSC_v3.4880,392,896 - 80,393,051UniSTSRGSC3.4
Celera876,115,392 - 76,115,547UniSTS
RH 3.4 Map8925.69UniSTS
Cytogenetic Map8q24UniSTS
RH138018  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2876,344,654 - 76,344,827 (+)MAPPERmRatBN7.2
Rnor_6.0882,526,081 - 82,526,253NCBIRnor6.0
Rnor_5.0882,127,490 - 82,127,662UniSTSRnor5.0
RGSC_v3.4880,411,717 - 80,411,889UniSTSRGSC3.4
Celera876,134,637 - 76,134,809UniSTS
RH 3.4 Map8925.59UniSTS
Cytogenetic Map8q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 76 75 44 25 44 6 203 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000014124   ⟹   ENSRNOP00000014124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl876,325,667 - 76,352,253 (-)Ensembl
Rnor_6.0 Ensembl882,506,934 - 82,533,689 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118239   ⟹   ENSRNOP00000079258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl876,327,796 - 76,365,720 (-)Ensembl
RefSeq Acc Id: NM_031613   ⟹   NP_113801
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8885,206,153 - 85,232,736 (-)NCBI
mRatBN7.2876,325,667 - 76,352,253 (-)NCBI
Rnor_6.0882,507,055 - 82,533,679 (-)NCBI
Rnor_5.0882,108,631 - 82,148,859 (-)NCBI
RGSC_v3.4880,392,806 - 80,419,315 (-)RGD
Celera876,115,302 - 76,142,235 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243407   ⟹   XP_006243469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8885,197,222 - 85,250,627 (-)NCBI
mRatBN7.2876,316,736 - 76,366,003 (-)NCBI
Rnor_6.0882,505,947 - 82,547,450 (-)NCBI
Rnor_5.0882,108,631 - 82,148,859 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243408   ⟹   XP_006243470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8885,197,222 - 85,233,300 (-)NCBI
mRatBN7.2876,316,736 - 76,352,805 (-)NCBI
Rnor_6.0882,505,947 - 82,537,445 (-)NCBI
Rnor_5.0882,108,631 - 82,148,859 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766331   ⟹   XP_008764553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8885,197,222 - 85,245,899 (-)NCBI
mRatBN7.2876,316,736 - 76,365,405 (-)NCBI
Rnor_6.0882,505,947 - 82,546,679 (-)NCBI
Sequence:
RefSeq Acc Id: NP_113801   ⟸   NM_031613
- UniProtKB: P70566 (UniProtKB/Swiss-Prot),   A6I1E0 (UniProtKB/TrEMBL),   A0A8I5ZMG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243469   ⟸   XM_006243407
- Peptide Label: isoform X1
- UniProtKB: P70566 (UniProtKB/Swiss-Prot),   A6I1E0 (UniProtKB/TrEMBL),   A0A8I5ZMG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243470   ⟸   XM_006243408
- Peptide Label: isoform X1
- UniProtKB: P70566 (UniProtKB/Swiss-Prot),   A6I1E0 (UniProtKB/TrEMBL),   A0A8I5ZMG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764553   ⟸   XM_008766331
- Peptide Label: isoform X1
- UniProtKB: P70566 (UniProtKB/Swiss-Prot),   A6I1E0 (UniProtKB/TrEMBL),   A0A8I5ZMG0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014124   ⟸   ENSRNOT00000014124

Name Modeler Protein Id AA Range Protein Structure
AF-P70566-F1-model_v2 AlphaFold P70566 1-351 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29812 BioCyc
Ensembl Genes ENSRNOG00000010447 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014124 ENTREZGENE
  ENSRNOT00000014124.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot
InterPro LRR_dom_sf UniProtKB/Swiss-Prot
  TMOD UniProtKB/Swiss-Prot
KEGG Report rno:58814 UniProtKB/Swiss-Prot
NCBI Gene 58814 ENTREZGENE
PANTHER PTHR10901 UniProtKB/Swiss-Prot
  PTHR10901:SF15 UniProtKB/Swiss-Prot
Pfam Tropomodulin UniProtKB/Swiss-Prot
PhenoGen Tmod2 PhenoGen
RatGTEx ENSRNOG00000010447 RatGTEx
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot
TIGR TC223086
UniProt A0A8I5ZMG0 ENTREZGENE, UniProtKB/TrEMBL
  A6I1E0 ENTREZGENE, UniProtKB/TrEMBL
  A6I1E3_RAT UniProtKB/TrEMBL
  A6I1E4_RAT UniProtKB/TrEMBL
  P70566 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Tmod2  tropomodulin 2       Name updated 70584 APPROVED

Note Type Note Reference
gene_expression mRNA and protein expressed predominantly in brain 61770
gene_physical_interaction protein binds to the neuron-specific isoform of tropomyosin (Tmbr3) 61770