Cimip1 (ciliary microtubule inner protein 1) - Rat Genome Database

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Gene: Cimip1 (ciliary microtubule inner protein 1) Rattus norvegicus
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Symbol: Cimip1
Name: ciliary microtubule inner protein 1
RGD ID: 1589960
Description: Predicted to be located in cilium. Orthologous to human CIMIP1 (ciliary microtubule inner protein 1); INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog); methotrexate (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C3h20orf85; hypothetical protein LOC689618; LOC689618; similar to human chromosome 20 open reading frame 85; similar to Protein C20orf85 homolog; uncharacterized protein C20orf85 homolog; uncharacterized protein LOC689618
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83182,733,242 - 182,740,733 (+)NCBIGRCr8
mRatBN7.23162,315,542 - 162,322,456 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3162,315,622 - 162,322,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3166,114,698 - 166,121,529 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03174,618,539 - 174,625,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03172,355,492 - 172,362,323 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03171,597,319 - 171,604,094 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3171,597,241 - 171,604,143 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03177,658,756 - 177,665,531 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43164,407,395 - 164,414,314 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3161,501,291 - 161,508,086 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cimip1Ratbenzo[a]pyrene increases methylationISOCIMIP1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of CIMIP1 5' UTR and Benzo(a)pyrene results in increased methylation of CIMIP1 promoterCTDPMID:27901495
Cimip1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of CIMIP1 mRNACTDPMID:25181051
Cimip1Ratmethotrexate increases expressionISOCIMIP1 (Homo sapiens)6480464Methotrexate results in increased expression of CIMIP1 mRNACTDPMID:24449571


Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cimip1Ratcilium located_inISOCIMIP1 (Homo sapiens)1624291 PMID:25786037RGDPMID:25786037
Cimip1Ratcilium located_inIEAUniProtKB:Q9H1P6 and ensembl:ENSP000003602101600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cimip1Ratprotein binding enablesISOCIMIP1 (Homo sapiens)1624291UniProtKB:O14936-4 more ...RGDPMID:32296183


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


Cimip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83182,733,242 - 182,740,733 (+)NCBIGRCr8
mRatBN7.23162,315,542 - 162,322,456 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3162,315,622 - 162,322,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3166,114,698 - 166,121,529 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03174,618,539 - 174,625,370 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03172,355,492 - 172,362,323 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03171,597,319 - 171,604,094 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3171,597,241 - 171,604,143 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03177,658,756 - 177,665,531 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43164,407,395 - 164,414,314 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3161,501,291 - 161,508,086 (+)NCBICelera
Cytogenetic Map3q42NCBI
CIMIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382058,150,902 - 58,161,150 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2058,150,902 - 58,161,150 (+)EnsemblGRCh38hg38GRCh38
GRCh372056,725,958 - 56,736,206 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362056,159,389 - 56,169,592 (+)NCBINCBI36Build 36hg18NCBI36
Build 342056,159,388 - 56,169,587NCBI
Celera2053,466,441 - 53,476,642 (+)NCBICelera
Cytogenetic Map20q13.32NCBI
HuRef2053,508,254 - 53,518,458 (+)NCBIHuRef
CHM1_12056,627,541 - 56,637,743 (+)NCBICHM1_1
T2T-CHM13v2.02059,930,302 - 59,940,549 (+)NCBIT2T-CHM13v2.0
Cimip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392173,364,385 - 173,370,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2173,364,379 - 173,370,294 (+)EnsemblGRCm39 Ensembl
GRCm382173,522,592 - 173,528,502 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2173,522,586 - 173,528,501 (+)EnsemblGRCm38mm10GRCm38
MGSCv372173,348,093 - 173,354,003 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362173,165,537 - 173,171,440 (+)NCBIMGSCv36mm8
Celera2179,488,998 - 179,495,238 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map296.88NCBI
Cimip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554451,357,173 - 1,370,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554451,360,659 - 1,370,748 (-)NCBIChiLan1.0ChiLan1.0
CIMIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22163,900,612 - 63,919,664 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12063,893,731 - 63,909,576 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02054,494,076 - 54,504,703 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12055,770,571 - 55,780,802 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2055,770,571 - 55,783,620 (+)Ensemblpanpan1.1panPan2
CIMIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12442,960,156 - 42,968,514 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2442,960,214 - 42,969,258 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2442,207,018 - 42,228,510 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02443,825,900 - 43,847,428 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2443,825,958 - 43,838,373 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12442,928,414 - 42,936,741 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02443,049,479 - 43,071,004 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02443,707,868 - 43,729,373 (+)NCBIUU_Cfam_GSD_1.0
Cimip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640182,541,774 - 182,548,910 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936530757,396 - 764,198 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936530757,396 - 764,198 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CIMIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1758,373,175 - 58,383,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11758,373,168 - 58,383,135 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21765,584,607 - 65,594,592 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CIMIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.125,971,913 - 5,982,108 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl25,971,474 - 5,982,161 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605054,026,368 - 54,036,563 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cimip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474124,482,358 - 24,489,495 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474124,482,338 - 24,489,508 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Cimip1
46 total Variants

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:48
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000029558
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 27 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat

1 to 10 of 27 rows
RH141945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23162,322,269 - 162,322,419 (+)MAPPERmRatBN7.2
Rnor_6.03171,603,909 - 171,604,058NCBIRnor6.0
Rnor_5.03177,665,346 - 177,665,495UniSTSRnor5.0
RGSC_v3.43164,414,129 - 164,414,278UniSTSRGSC3.4
Celera3161,507,901 - 161,508,050UniSTS
RH 3.4 Map31496.9UniSTS
Cytogenetic Map3q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 5 1 19 15 12 5 10 5 33 16 15 2 37 7



Ensembl Acc Id: ENSRNOT00000029558   ⟹   ENSRNOP00000030660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3162,315,622 - 162,322,455 (+)Ensembl
Rnor_6.0 Ensembl3171,597,241 - 171,604,143 (+)Ensembl
RefSeq Acc Id: NM_001109542   ⟹   NP_001103012
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83182,733,901 - 182,740,732 (+)NCBI
mRatBN7.23162,315,622 - 162,322,455 (+)NCBI
Rnor_6.03171,597,319 - 171,604,094 (+)NCBI
Rnor_5.03177,658,756 - 177,665,531 (+)NCBI
RGSC_v3.43164,407,395 - 164,414,314 (+)RGD
Celera3161,501,291 - 161,508,086 (+)RGD
Sequence:
RefSeq Acc Id: XM_063284577   ⟹   XP_063140647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83182,733,242 - 182,740,733 (+)NCBI
Protein RefSeqs NP_001103012 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140647 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL85112 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030660
  ENSRNOP00000030660.2
RefSeq Acc Id: NP_001103012   ⟸   NM_001109542
- UniProtKB: D4A8H6 (UniProtKB/TrEMBL),   A6KL04 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030660   ⟸   ENSRNOT00000029558
RefSeq Acc Id: XP_063140647   ⟸   XM_063284577
- Peptide Label: isoform X1
- UniProtKB: A6KL04 (UniProtKB/TrEMBL),   D4A8H6 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-D4A8H6-F1-model_v2 AlphaFold D4A8H6 1-135 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692714
Promoter ID:EPDNEW_R3239
Type:initiation region
Name:LOC689618_1
Description:similar to Protein C20orf85 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03171,597,303 - 171,597,363EPDNEW


1 to 14 of 14 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46489 BioCyc
Ensembl Genes ENSRNOG00000028533 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029558 ENTREZGENE
  ENSRNOT00000029558.4 UniProtKB/TrEMBL
InterPro Uncharacterised_C20orf85 UniProtKB/TrEMBL
KEGG Report rno:689618 UniProtKB/TrEMBL
NCBI Gene 689618 ENTREZGENE
PANTHER CHROMOSOME 20 ORF85 FAMILY MEMBER UniProtKB/TrEMBL
  RCG40914 UniProtKB/TrEMBL
Pfam LLC1 UniProtKB/TrEMBL
PhenoGen Cimip1 PhenoGen
RatGTEx ENSRNOG00000028533 RatGTEx
UniProt A6KL04 ENTREZGENE, UniProtKB/TrEMBL
  D4A8H6 ENTREZGENE, UniProtKB/TrEMBL
1 to 14 of 14 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-05 Cimip1  ciliary microtubule inner protein 1  C3h20orf85  similar to human chromosome 20 open reading frame 85  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-08-02 C3h20orf85  similar to human chromosome 20 open reading frame 85  LOC689618  similar to Protein C20orf85 homolog  Name and Symbol changed 629549 APPROVED
2008-01-09 LOC689618  similar to Protein C20orf85 homolog  LOC679098  similar to Protein C20orf85 homolog  Data merged from RGD:1593029 1643240 APPROVED
2006-11-20 LOC689618  similar to Protein C20orf85 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC679098  similar to Protein C20orf85 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL