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Gene: Lsmem2 (leucine-rich single-pass membrane protein 2) Rattus norvegicus

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Symbol:

Lsmem2

Name:

leucine-rich single-pass membrane protein 2

RGD ID:

1589957

Description:

Predicted to be located in membrane. Orthologous to human LSMEM2 (leucine rich single-pass membrane protein 2); INTERACTS WITH acrylamide; alpha-Zearalanol; glyphosate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC689621; LOC689621

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,144,498 - 117,149,300 (-)	NCBI		GRCr8
mRatBN7.2	8	108,265,855 - 108,270,656 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,266,345 - 108,279,115 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	8	116,348,406 - 116,353,092 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,348,751 - 116,349,896 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	115,704,246 - 115,709,043 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	112,840,587 - 112,844,108 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	8	107,572,857 - 107,577,547 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lsmem2	Rat	Aicardi-Goutieres Syndrome 1		ISO	LSMEM2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Aicardi-Goutieres syndrome 1	ClinVar	PMID:16845398 and PMID:28492532
Lsmem2	Rat	developmental and epileptic encephalopathy		ISO	LSMEM2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental and epileptic encephalopathy	ClinVar	PMID:24358150 and PMID:28492532
Lsmem2	Rat	early infantile epileptic encephalopathy		ISO	LSMEM2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Early infantile epileptic encephalopathy	ClinVar	PMID:24358150 and PMID:28492532
Lsmem2	Rat	primary ciliary dyskinesia		ISO	LSMEM2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Primary ciliary dyskinesia	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lsmem2	Rat	17beta-estradiol	increases expression	ISO	LSMEM2 (Homo sapiens)	6480464	Estradiol results in increased expression of LSMEM2 mRNA	CTD	PMID:31614463
Lsmem2	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of LSMEM2 mRNA	CTD	PMID:28959563
Lsmem2	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] affects the expression of LSMEM2 mRNA	CTD	PMID:35163327
Lsmem2	Rat	aristolochic acid A	increases expression	ISO	LSMEM2 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of LSMEM2 mRNA	CTD	PMID:33212167
Lsmem2	Rat	beta-lapachone	increases expression	ISO	LSMEM2 (Homo sapiens)	6480464	beta-lapachone results in increased expression of LSMEM2 mRNA	CTD	PMID:38218311
Lsmem2	Rat	doxorubicin	increases expression	ISO	LSMEM2 (Homo sapiens)	6480464	Doxorubicin results in increased expression of LSMEM2 mRNA	CTD	PMID:29803840
Lsmem2	Rat	ethylparaben	decreases expression	ISO	LSMEM2 (Homo sapiens)	6480464	ethyl-p-hydroxybenzoate results in decreased expression of LSMEM2 mRNA	CTD	PMID:37690743
Lsmem2	Rat	glyphosate	increases methylation	EXP		6480464	Glyphosate results in increased methylation of LSMEM2 gene	CTD	PMID:31011160
Lsmem2	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] affects the expression of LSMEM2 mRNA	CTD	PMID:35163327
Lsmem2	Rat	sodium arsenite	increases expression	ISO	LSMEM2 (Homo sapiens)	6480464	sodium arsenite results in increased expression of LSMEM2 mRNA	CTD	PMID:38568856
Lsmem2	Rat	sodium arsenite	decreases expression	ISO	LSMEM2 (Homo sapiens)	6480464	sodium arsenite results in decreased expression of LSMEM2 mRNA	CTD	PMID:34032870
Lsmem2	Rat	sunitinib	decreases expression	ISO	LSMEM2 (Homo sapiens)	6480464	Sunitinib results in decreased expression of LSMEM2 mRNA	CTD	PMID:31533062
Lsmem2	Rat	valproic acid	increases methylation	ISO	LSMEM2 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of LSMEM2 gene	CTD	PMID:29154799

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lsmem2	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lsmem2	Rat	protein binding	enables	ISO	LSMEM2 (Homo sapiens)	1624291	UniProtKB:A2RU14 more ...	RGD	PMID:25416956 more ...

Lsmem2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,144,498 - 117,149,300 (-)	NCBI		GRCr8
mRatBN7.2	8	108,265,855 - 108,270,656 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,266,345 - 108,279,115 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	8	116,348,406 - 116,353,092 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,348,751 - 116,349,896 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	115,704,246 - 115,709,043 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	112,840,587 - 112,844,108 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	8	107,572,857 - 107,577,547 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

LSMEM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	50,277,907 - 50,288,114 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	50,279,087 - 50,288,114 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	50,316,518 - 50,325,545 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	50,291,522 - 50,300,549 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	50,289,343 - 50,298,377 (+)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	50,372,254 - 50,381,288 (+)	NCBI		HuRef
CHM1_1	3	50,268,801 - 50,277,851 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	50,307,257 - 50,317,471 (+)	NCBI		T2T-CHM13v2.0

Lsmem2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	107,469,825 - 107,475,189 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	107,469,829 - 107,474,274 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	107,592,626 - 107,597,990 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	107,592,630 - 107,597,075 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	107,495,398 - 107,499,406 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,451,168 - 107,455,176 (-)	NCBI		MGSCv36	mm8
Celera	9	107,201,848 - 107,205,857 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	58.28	NCBI

Lsmem2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	2,096,770 - 2,100,876 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	2,096,231 - 2,101,541 (+)	NCBI	ChiLan1.0	ChiLan1.0

LSMEM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	50,260,361 - 50,271,169 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	50,265,136 - 50,275,944 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	50,206,431 - 50,216,716 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	51,440,642 - 51,451,467 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	51,441,739 - 51,451,467 (+)	Ensembl	panpan1.1		panPan2

LSMEM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	39,053,152 - 39,058,467 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	39,053,950 - 39,054,717 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	38,974,188 - 38,979,081 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	39,409,187 - 39,414,087 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	39,409,985 - 39,410,752 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	38,777,009 - 38,781,902 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	39,180,520 - 39,185,405 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	39,460,589 - 39,465,481 (-)	NCBI		UU_Cfam_GSD_1.0

Lsmem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	65,058,277 - 65,064,970 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936529	1,819,848 - 1,825,472 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LSMEM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	32,753,199 - 32,757,034 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	32,752,515 - 32,757,042 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	35,928,407 - 35,935,562 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LSMEM2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	11,666,171 - 11,675,465 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666041	155,311,530 - 155,319,781 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lsmem2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	4,144,588 - 4,148,953 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Lsmem2
23 total Variants

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	73473045	118473045	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	69349194	112783834	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	71888757	116888757	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	71888757	116888757	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
631653	Bp125	Blood pressure QTL 125	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	66142385	111142385	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	70513503	118219066	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	102370617	108923645	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	89265192	114019816	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	71888757	116888757	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	71888757	116888757	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat

RH131906

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,271,751 - 108,271,957 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,353,880 - 116,354,085	NCBI	Rnor6.0
Rnor_5.0	8	115,710,139 - 115,710,344	UniSTS	Rnor5.0
RGSC_v3.4	8	112,845,518 - 112,845,723	UniSTS	RGSC3.4
Celera	8	107,578,335 - 107,578,540	UniSTS
RH 3.4 Map	8	1118.6	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH142073

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,271,226 - 108,271,420 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,353,355 - 116,353,548	NCBI	Rnor6.0
Rnor_5.0	8	115,709,614 - 115,709,807	UniSTS	Rnor5.0
RGSC_v3.4	8	112,844,993 - 112,845,186	UniSTS	RGSC3.4
Celera	8	107,577,810 - 107,578,003	UniSTS
RH 3.4 Map	8	1118.6	UniSTS
Cytogenetic Map	8	q32	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	109	54	53	22	25	22	6	181	97	89	45	58	31


RefSeq Transcripts	NM_001430399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001071401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002727102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006226561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC139927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000087306 ⟹ ENSRNOP00000075362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	108,266,664 - 108,267,783 (-)	Ensembl
Rnor_6.0 Ensembl	8	116,348,751 - 116,349,896 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094298 ⟹ ENSRNOP00000085522

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	108,266,345 - 108,279,115 (-)	Ensembl

RefSeq Acc Id:

XM_001071401 ⟹ XP_001071401

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,144,498 - 117,149,300 (-)	NCBI
mRatBN7.2	8	108,265,855 - 108,270,656 (-)	NCBI
Rnor_6.0	8	116,348,407 - 116,353,092 (-)	NCBI
Rnor_5.0	8	115,704,246 - 115,709,043 (-)	NCBI
RGSC_v3.4	8	112,840,587 - 112,844,108 (-)	RGD

Sequence:

show sequence

TTTCCCCATGGTTATAGTTTAATACTAGAAATAGCAGTTTCTAATCCCGGTCTGACCACTGTATGGGTGCCCTTGTAGAGCTGCCAGACCCTTGGCATTGGGCTCCAGTTGCACCCAGTCCACCACCC
CCAGTATCTGGTACTAGATGGTCACACAGTGGTGGGTGGTTGTCTCCAATTGCTGGGAGGAGATGGCTAGTCTGTGGGTAAAGGGTCTGAGAGAGAGGGATGGCTGAGCGGACCTGTGCAGGGTTCCT
TTGCTACCATGCTGCATGGTGCGTGCTGAGCATTGGGATGAAGGCTCCCAAGTCTGGGTGTGTATAAAGTTGGTGTGGTTTTCCGAGAAGTTCCTTCTGTCCATGTGCTAGCAGAGGCTTGCCCTTGG
CTGAGCCCCATCACTAAGTAGGTAGTTTAGGCCGGCCCATCCAGGTCACTCTGCCCCTTTTCATGGTTCAGAGCTGCCCTCTCTAAATATAGTTCAGGGAAAGTGAGCTCAGGCCTATTTCAAGACCA
GGTTGGGAGGCAGCCAGGCCTCTCCTAGAATCTGAAAGAAGCCACTGCTGCCTTTGTCCAGTTCTGCTACTGGGCACTCTCATTGGGCCTCTGACTACCTACCAACTGCCATGCCTGAGGAGATCCAA
GAAGATACTGTGTTGCCAATGCAGAACCAGAGGCACAGGCCAACACTGGCTCCTAACCACGTGCAGGAGGTGCATCTGCATCGAGTGGAGTCCATCAGTGACCTGCACAGTGGAGGCTCACTACGGCC
CTGTCTGGCTGAAGAGGCGCAGGCCTGGGAGGAGCTTCTGGGTGTCTTACCACCGTCACTGTGCACCCAAGCTGCTTGCAGCCCCATGTGTGGCCGTGGGGGGTTCCTTCTGCTATTGGCACTGCTAG
TGTTCACCTGCCTGGCACTAGCCATCGTAGCTGTCTACCTAAGTGTGCTGCAGAGTGAATCCCTGAGGGTGTTGGCACACACGCTGCGCACACAAGAGGAGACTCTGCTCAAATTGCGTCTGGCTAGC
CTCAGCCAGCTAAGAAGGCTCAACTCCAGTGAGGCTCGGGCACCCAGCTGAGATACCATCTGTATGTGAGACTGTGATGGGGGACAAAGGGACTTCTGGCAGGTCTCTGTTCTCCCACTGATGGCCTC
ATCTGCACTATTCCTTGGGGAGATTTCTTCACAAGCCTGACGTTCCTCCACAGCTGCCTGTCTCTCTTGACCGCTTCAGGCCAGGCCTGAGCAAAGCTCTTGGTGCCAAGGCCCTGCTGTGGTTAGCC
AAAGGTCAGAGGATGGAGCACCAGTCTTTTCCTGGTCCCCCGTCAGCACCCTCTGGTCACCCCCAGATAGGAAGTTCAGAAGTCTAGAAATAGCTGTCCCAGCTCAGCCACCCACTCTGCCAGGCCTC
CTAGCAGGGGGTCCAGCCTCAGCTCAGGCAAGCCAGGCTGAGTTGGGGAACTACATGTCCTGCCATGGAGGACAAAGGTGAGGTAGAGCTAGTCGGGGCCAACCTGGGGTGGCAGACGGAGGGAGGGC
AGGCACAAGACTCAGGAGAGAGAGGGGTTGGGGATTTAGCTCAGTGGTAGAGCACTTGCCTAGCAAGCGCAAGGCCCTGGG

hide sequence

RefSeq Acc Id:

XM_039082622 ⟹ XP_038938550

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,144,498 - 117,149,300 (-)	NCBI
mRatBN7.2	8	108,265,855 - 108,270,656 (-)	NCBI


Protein RefSeqs	NP_001417328	(Get FASTA)	NCBI Sequence Viewer
	XP_001071401	(Get FASTA)	NCBI Sequence Viewer
	XP_038938550	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075362
	ENSRNOP00000075362.2
	ENSRNOP00000085522.1
	ENSRNOP00000108614

RefSeq Acc Id:	XP_001071401 ⟸ XM_001071401
- Peptide Label:	isoform X2
- Sequence:	show sequence MPEEIQEDTVLPMQNQRHRPTLAPNHVQEVHLHRVESISDLHSGGSLRPCLAEEAQAWEELLGVLPPSLCTQAACSPMCGRGGFLLLLALLVFTCLALAIVAVYLSVLQSESLRVLAHTLRTQEETLL KLRLASLSQLRRLNSSEARAPS hide sequence

Ensembl Acc Id:

ENSRNOP00000075362 ⟸ ENSRNOT00000087306

RefSeq Acc Id:	XP_038938550 ⟸ XM_039082622
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2KAD9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085522 ⟸ ENSRNOT00000094298

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2KAD9-F1-model_v2	AlphaFold	A0A0G2KAD9	1-175	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-29186	BioCyc
Ensembl Genes	ENSRNOG00000052634	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000087306	ENTREZGENE
	ENSRNOT00000087306.2	UniProtKB/TrEMBL
	ENSRNOT00000094298.1	UniProtKB/TrEMBL
	ENSRNOT00000157156	ENTREZGENE
InterPro	DUF4714	UniProtKB/TrEMBL
KEGG Report	rno:689621	UniProtKB/TrEMBL
NCBI Gene	689621	ENTREZGENE
PANTHER	LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2	UniProtKB/TrEMBL
	PTHR37333	UniProtKB/TrEMBL
Pfam	DUF4714	UniProtKB/TrEMBL
PhenoGen	Lsmem2	PhenoGen
RatGTEx	ENSRNOG00000052634	RatGTEx
UniProt	A0A0G2KAD9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A425	ENTREZGENE, UniProtKB/TrEMBL
	A6I2Z0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-03-20	Lsmem2	leucine-rich single-pass membrane protein 2	LOC689621	hypothetical protein LOC689621	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC689621	hypothetical protein LOC689621	LOC686484	hypothetical protein LOC686484	Data merged from RGD:1597600	1643240	APPROVED
2006-11-20	LOC689621	hypothetical protein LOC689621			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC686484	hypothetical protein LOC686484			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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