Symbol:
Cnn2
Name:
calponin 2
RGD ID:
1589807
Description:
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to act upstream of or within several processes, including cellular response to mechanical stimulus; negative regulation of macrophage migration; and negative regulation of phagocytosis. Predicted to be located in stress fiber. Predicted to be active in actin cytoskeleton. Orthologous to human CNN2 (calponin 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
calponin-2; LOC690976; similar to Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CNN2 (calponin 2) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther, Treefam
Mus musculus (house mouse):
Cnn2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Cnn2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
CNN2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
CNN2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Cnn2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CNN2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
CNN2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Cnn2 (calponin 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
CNN2 (calponin 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Cnn2 (calponin 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
cnn2 (calponin 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
Chd64
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
SCP1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoInspector|SonicParanoid)
Caenorhabditis elegans (roundworm):
cpn-2
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
CG5023
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
cnn2
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 7 10,363,141 - 10,370,312 (-) NCBI GRCr8 mRatBN7.2 7 9,712,505 - 9,719,678 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 7 9,712,516 - 9,719,656 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 7 12,594,690 - 12,601,905 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 7 14,470,026 - 14,477,227 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 7 12,331,153 - 12,338,424 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 7 12,782,459 - 12,787,977 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 7 12,782,491 - 12,787,750 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 7 12,952,193 - 12,957,718 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 7 11,223,451 - 11,232,524 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 7 7,888,183 - 7,895,312 (-) NCBI Celera Cytogenetic Map 7 q11 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Cnn2 Rat (S)-nicotine multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Cnn2 Rat 1,2-dimethylhydrazine increases expression ISO Cnn2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of CNN2 mRNA CTD PMID:22206623 Cnn2 Rat 1,2-dimethylhydrazine multiple interactions ISO Cnn2 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CNN2 mRNA] CTD PMID:22206623 Cnn2 Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Cnn2 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Cnn2 Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Cnn2 Rat 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CNN2 mRNA CTD PMID:32741896 Cnn2 Rat 17beta-estradiol increases expression ISO CNN2 (Homo sapiens) 6480464 Estradiol results in increased expression of CNN2 mRNA CTD PMID:31614463 Cnn2 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CNN2 mRNA CTD PMID:32741896 Cnn2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Cnn2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CNN2 mRNA CTD PMID:21570461 Cnn2 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CNN2 mRNA CTD PMID:16054899 Cnn2 Rat 4,4'-sulfonyldiphenol increases expression ISO Cnn2 (Mus musculus) 6480464 bisphenol S results in increased expression of CNN2 mRNA CTD PMID:30951980 Cnn2 Rat 4-hydroxyphenyl retinamide increases expression ISO Cnn2 (Mus musculus) 6480464 Fenretinide results in increased expression of CNN2 mRNA CTD PMID:28973697 Cnn2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CNN2 mRNA CTD PMID:30047161 Cnn2 Rat acrylamide increases expression ISO CNN2 (Homo sapiens) 6480464 Acrylamide results in increased expression of CNN2 mRNA CTD PMID:32763439 Cnn2 Rat actinomycin D multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of CNN2 protein CTD PMID:38460933 Cnn2 Rat aflatoxin B1 decreases expression ISO Cnn2 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of CNN2 mRNA CTD PMID:19770486 Cnn2 Rat all-trans-retinoic acid increases expression ISO CNN2 (Homo sapiens) 6480464 Tretinoin results in increased expression of CNN2 mRNA CTD PMID:16012519 and PMID:33167477 Cnn2 Rat all-trans-retinoic acid multiple interactions ISO Cnn2 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of CNN2 mRNA CTD PMID:30951980 Cnn2 Rat alpha-Zearalanol increases expression EXP 6480464 Zeranol results in increased expression of CNN2 mRNA CTD PMID:35163327 Cnn2 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of CNN2 mRNA CTD PMID:30047161 Cnn2 Rat andrographolide multiple interactions ISO Cnn2 (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CNN2 mRNA CTD PMID:19737545 Cnn2 Rat benzo[a]pyrene decreases expression ISO Cnn2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of CNN2 mRNA CTD PMID:19770486 Cnn2 Rat benzo[a]pyrene increases expression ISO Cnn2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of CNN2 mRNA CTD PMID:22228805 and PMID:32417428 Cnn2 Rat beta-lapachone decreases expression ISO CNN2 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of CNN2 mRNA CTD PMID:38218311 Cnn2 Rat beta-naphthoflavone multiple interactions ISO Cnn2 (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CNN2 mRNA CTD PMID:19737545 Cnn2 Rat bis(2-ethylhexyl) phthalate decreases expression ISO CNN2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of CNN2 protein CTD PMID:31163220 Cnn2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CNN2 mRNA CTD PMID:25181051 Cnn2 Rat bisphenol A decreases expression ISO Cnn2 (Mus musculus) 6480464 bisphenol A results in decreased expression of CNN2 protein CTD PMID:35999755 Cnn2 Rat bisphenol A multiple interactions ISO CNN2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CNN2 gene CTD PMID:31601247 Cnn2 Rat bisphenol A increases expression ISO Cnn2 (Mus musculus) 6480464 bisphenol A results in increased expression of CNN2 mRNA CTD PMID:30951980 and PMID:32156529 Cnn2 Rat bisphenol A decreases expression ISO CNN2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of CNN2 mRNA and bisphenol A results in decreased expression of CNN2 protein CTD PMID:29275510 and PMID:37567409 Cnn2 Rat bisphenol AF increases expression ISO CNN2 (Homo sapiens) 6480464 bisphenol AF results in increased expression of CNN2 protein CTD PMID:34186270 Cnn2 Rat bisphenol F multiple interactions ISO Cnn2 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of CNN2 mRNA CTD PMID:30951980 Cnn2 Rat bisphenol F increases expression ISO CNN2 (Homo sapiens) 6480464 bisphenol F results in increased expression of CNN2 protein CTD PMID:34186270 Cnn2 Rat bisphenol F decreases expression ISO Cnn2 (Mus musculus) 6480464 bisphenol F results in decreased expression of CNN2 mRNA CTD PMID:38685157 Cnn2 Rat bisphenol F increases expression ISO Cnn2 (Mus musculus) 6480464 bisphenol F results in increased expression of CNN2 mRNA CTD PMID:30951980 Cnn2 Rat butanal increases expression ISO CNN2 (Homo sapiens) 6480464 butyraldehyde results in increased expression of CNN2 mRNA CTD PMID:26079696 Cnn2 Rat caffeine multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Cnn2 Rat calcipotriol multiple interactions ISO Cnn2 (Mus musculus) 6480464 calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA] and Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA]] CTD PMID:38992766 Cnn2 Rat calcitriol multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of CNN2 mRNA CTD PMID:21592394 Cnn2 Rat calcitriol increases expression ISO CNN2 (Homo sapiens) 6480464 Calcitriol results in increased expression of CNN2 mRNA CTD PMID:21592394 Cnn2 Rat chlorpyrifos increases expression ISO Cnn2 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of CNN2 mRNA CTD PMID:37019170 Cnn2 Rat chromium(6+) multiple interactions ISO CNN2 (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of CNN2 mRNA CTD PMID:38479592 Cnn2 Rat cisplatin increases expression ISO Cnn2 (Mus musculus) 6480464 Cisplatin results in increased expression of CNN2 mRNA CTD PMID:21151649 Cnn2 Rat clotrimazole increases expression EXP 6480464 Clotrimazole results in increased expression of CNN2 mRNA CTD PMID:30047161 Cnn2 Rat cobalt dichloride decreases expression ISO CNN2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of CNN2 mRNA CTD PMID:19320972 Cnn2 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of CNN2 mRNA CTD PMID:26577399 and PMID:27523638 Cnn2 Rat cyclosporin A increases expression ISO CNN2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of CNN2 mRNA CTD PMID:25562108 Cnn2 Rat dexamethasone multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CNN2 mRNA CTD PMID:16054899 Cnn2 Rat dextran sulfate decreases expression ISO Cnn2 (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of CNN2 protein CTD PMID:35999755 Cnn2 Rat diazinon increases methylation ISO CNN2 (Homo sapiens) 6480464 Diazinon results in increased methylation of CNN2 gene CTD PMID:22964155 Cnn2 Rat dibutyl phthalate increases expression ISO Cnn2 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of CNN2 mRNA CTD PMID:17361019 and PMID:21266533 Cnn2 Rat dicrotophos increases expression ISO CNN2 (Homo sapiens) 6480464 dicrotophos results in increased expression of CNN2 mRNA CTD PMID:28302478 Cnn2 Rat dioxygen affects expression ISO Cnn2 (Mus musculus) 6480464 Oxygen deficiency affects the expression of CNN2 mRNA CTD PMID:17193925 Cnn2 Rat doxorubicin increases expression ISO CNN2 (Homo sapiens) 6480464 Doxorubicin results in increased expression of CNN2 mRNA CTD PMID:29803840 Cnn2 Rat elemental selenium increases expression ISO CNN2 (Homo sapiens) 6480464 Selenium results in increased expression of CNN2 mRNA CTD PMID:19244175 Cnn2 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of CNN2 mRNA CTD PMID:29391264 Cnn2 Rat entinostat increases expression ISO CNN2 (Homo sapiens) 6480464 entinostat results in increased expression of CNN2 mRNA CTD PMID:32870474 Cnn2 Rat enzyme inhibitor multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CNN2 protein CTD PMID:23301498 Cnn2 Rat fenamidone increases expression ISO Cnn2 (Mus musculus) 6480464 fenamidone results in increased expression of CNN2 mRNA CTD PMID:27029645 Cnn2 Rat folic acid decreases expression ISO Cnn2 (Mus musculus) 6480464 Folic Acid results in decreased expression of CNN2 mRNA CTD PMID:25629700 Cnn2 Rat folic acid multiple interactions ISO Cnn2 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of CNN2 mRNA] CTD PMID:22206623 Cnn2 Rat fulvestrant multiple interactions ISO CNN2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CNN2 gene CTD PMID:31601247 Cnn2 Rat furfural multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of CNN2 protein CTD PMID:38598786 Cnn2 Rat genistein multiple interactions ISO CNN2 (Homo sapiens) 6480464 ESR2 promotes the reaction [Genistein results in decreased expression of CNN2 protein] CTD PMID:20884965 Cnn2 Rat genistein decreases expression ISO CNN2 (Homo sapiens) 6480464 Genistein results in decreased expression of CNN2 mRNA and Genistein results in decreased expression of CNN2 protein CTD PMID:20884965 and PMID:22228119 Cnn2 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of CNN2 mRNA CTD PMID:33387578 Cnn2 Rat glafenine increases expression EXP 6480464 Glafenine results in increased expression of CNN2 mRNA CTD PMID:24136188 Cnn2 Rat isobutanol multiple interactions ISO CNN2 (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CNN2 mRNA CTD PMID:29432896 Cnn2 Rat ivermectin decreases expression ISO CNN2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of CNN2 protein CTD PMID:32959892 Cnn2 Rat leflunomide decreases expression EXP 6480464 leflunomide results in decreased expression of CNN2 mRNA CTD PMID:24136188 Cnn2 Rat leflunomide increases expression ISO CNN2 (Homo sapiens) 6480464 leflunomide results in increased expression of CNN2 mRNA CTD PMID:28988120 Cnn2 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of CNN2 mRNA CTD PMID:30047161 Cnn2 Rat N-methyl-4-phenylpyridinium increases expression ISO CNN2 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CNN2 mRNA CTD PMID:24810058 and PMID:32870474 Cnn2 Rat niclosamide increases expression ISO CNN2 (Homo sapiens) 6480464 Niclosamide results in increased expression of CNN2 mRNA CTD PMID:36318118 Cnn2 Rat nicotine multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 Cnn2 Rat nitrates multiple interactions ISO Cnn2 (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of CNN2 mRNA CTD PMID:35964746 Cnn2 Rat Nutlin-3 multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of CNN2 protein CTD PMID:38460933 Cnn2 Rat paracetamol affects expression ISO Cnn2 (Mus musculus) 6480464 Acetaminophen affects the expression of CNN2 mRNA CTD PMID:17562736 Cnn2 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CNN2 mRNA CTD PMID:33387578 Cnn2 Rat perfluorooctanoic acid decreases expression ISO CNN2 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of CNN2 protein CTD PMID:26879310 Cnn2 Rat phenobarbital decreases expression ISO Cnn2 (Mus musculus) 6480464 Phenobarbital results in decreased expression of CNN2 mRNA CTD PMID:25270620 Cnn2 Rat phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CNN2 mRNA CTD PMID:30047161 Cnn2 Rat pirinixic acid decreases expression ISO Cnn2 (Mus musculus) 6480464 pirinixic acid results in decreased expression of CNN2 mRNA CTD PMID:17426115 Cnn2 Rat propanal increases expression ISO CNN2 (Homo sapiens) 6480464 propionaldehyde results in increased expression of CNN2 mRNA CTD PMID:26079696 Cnn2 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of CNN2 mRNA CTD PMID:28374803 Cnn2 Rat rotenone increases expression ISO Cnn2 (Mus musculus) 6480464 Rotenone results in increased expression of CNN2 mRNA CTD PMID:32937126 Cnn2 Rat rotenone increases expression ISO CNN2 (Homo sapiens) 6480464 Rotenone results in increased expression of CNN2 mRNA CTD PMID:29955902 and PMID:32870474 Cnn2 Rat SB 431542 multiple interactions ISO CNN2 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of CNN2 protein CTD PMID:37664457 Cnn2 Rat selenium atom increases expression ISO CNN2 (Homo sapiens) 6480464 Selenium results in increased expression of CNN2 mRNA CTD PMID:19244175 Cnn2 Rat silver atom decreases expression ISO Cnn2 (Mus musculus) 6480464 Silver results in decreased expression of CNN2 mRNA CTD PMID:27131904 Cnn2 Rat silver(0) decreases expression ISO Cnn2 (Mus musculus) 6480464 Silver results in decreased expression of CNN2 mRNA CTD PMID:27131904 Cnn2 Rat sodium chloride multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of CNN2 protein CTD PMID:38598786 Cnn2 Rat testosterone multiple interactions ISO CNN2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of CNN2 mRNA CTD PMID:21592394 Cnn2 Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CNN2 mRNA CTD PMID:32741896 Cnn2 Rat testosterone increases expression ISO CNN2 (Homo sapiens) 6480464 Testosterone results in increased expression of CNN2 mRNA CTD PMID:21592394 Cnn2 Rat tetrachloromethane increases expression ISO Cnn2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of CNN2 mRNA CTD PMID:31919559 and PMID:38992766 Cnn2 Rat tetrachloromethane multiple interactions ISO Cnn2 (Mus musculus) 6480464 calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA] more ... CTD PMID:38992766 Cnn2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CNN2 mRNA CTD PMID:34492290 Cnn2 Rat titanium dioxide decreases methylation ISO Cnn2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of CNN2 gene and titanium dioxide results in decreased methylation of CNN2 promoter alternative form CTD PMID:35295148 Cnn2 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of CNN2 mRNA CTD PMID:33387578 Cnn2 Rat triphenyl phosphate affects expression ISO CNN2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of CNN2 mRNA CTD PMID:37042841 Cnn2 Rat valproic acid increases methylation ISO CNN2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of CNN2 gene CTD PMID:29154799 Cnn2 Rat valproic acid increases expression ISO Cnn2 (Mus musculus) 6480464 Valproic Acid results in increased expression of CNN2 mRNA CTD PMID:19136453 and PMID:24896083 Cnn2 Rat valproic acid affects expression ISO Cnn2 (Mus musculus) 6480464 Valproic Acid affects the expression of CNN2 mRNA CTD PMID:17292431 Cnn2 Rat vancomycin decreases expression ISO Cnn2 (Mus musculus) 6480464 Vancomycin results in decreased expression of CNN2 mRNA CTD PMID:18930951 Cnn2 Rat verteporfin multiple interactions ISO Cnn2 (Mus musculus) 6480464 Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA]] and Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA] CTD PMID:38992766 Cnn2 Rat ziram increases expression ISO CNN2 (Homo sapiens) 6480464 Ziram results in increased expression of CNN2 mRNA CTD PMID:32870474
(S)-nicotine (ISO) 1,2-dimethylhydrazine (ISO) 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO) 17beta-estradiol (EXP,ISO) 17beta-estradiol 3-benzoate (EXP) 2,3,7,8-tetrachlorodibenzodioxine (ISO) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 6-propyl-2-thiouracil (EXP) acrylamide (ISO) actinomycin D (ISO) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) alpha-Zearalanol (EXP) amitrole (EXP) andrographolide (ISO) benzo[a]pyrene (ISO) beta-lapachone (ISO) beta-naphthoflavone (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) bisphenol F (ISO) butanal (ISO) caffeine (ISO) calcipotriol (ISO) calcitriol (ISO) chlorpyrifos (ISO) chromium(6+) (ISO) cisplatin (ISO) clotrimazole (EXP) cobalt dichloride (ISO) Cuprizon (EXP) cyclosporin A (ISO) dexamethasone (ISO) dextran sulfate (ISO) diazinon (ISO) dibutyl phthalate (ISO) dicrotophos (ISO) dioxygen (ISO) doxorubicin (ISO) elemental selenium (ISO) endosulfan (EXP) entinostat (ISO) enzyme inhibitor (ISO) fenamidone (ISO) folic acid (ISO) fulvestrant (ISO) furfural (ISO) genistein (ISO) gentamycin (EXP) glafenine (EXP) isobutanol (ISO) ivermectin (ISO) leflunomide (EXP,ISO) methimazole (EXP) N-methyl-4-phenylpyridinium (ISO) niclosamide (ISO) nicotine (ISO) nitrates (ISO) Nutlin-3 (ISO) paracetamol (EXP,ISO) perfluorooctanoic acid (ISO) phenobarbital (EXP,ISO) pirinixic acid (ISO) propanal (ISO) rotenone (EXP,ISO) SB 431542 (ISO) selenium atom (ISO) silver atom (ISO) silver(0) (ISO) sodium chloride (ISO) testosterone (EXP,ISO) tetrachloromethane (ISO) thioacetamide (EXP) titanium dioxide (ISO) trichloroethene (EXP) triphenyl phosphate (ISO) valproic acid (ISO) vancomycin (ISO) verteporfin (ISO) ziram (ISO)
Cnn2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 7 10,363,141 - 10,370,312 (-) NCBI GRCr8 mRatBN7.2 7 9,712,505 - 9,719,678 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 7 9,712,516 - 9,719,656 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 7 12,594,690 - 12,601,905 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 7 14,470,026 - 14,477,227 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 7 12,331,153 - 12,338,424 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 7 12,782,459 - 12,787,977 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 7 12,782,491 - 12,787,750 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 7 12,952,193 - 12,957,718 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 7 11,223,451 - 11,232,524 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 7 7,888,183 - 7,895,312 (-) NCBI Celera Cytogenetic Map 7 q11 NCBI
CNN2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 1,026,608 - 1,039,065 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 1,026,586 - 1,039,068 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 1,026,607 - 1,039,064 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 977,298 - 990,064 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 977,297 - 990,063 NCBI Celera 19 958,638 - 969,897 (+) NCBI Celera Cytogenetic Map 19 p13.3 NCBI HuRef 19 799,427 - 811,654 (+) NCBI HuRef CHM1_1 19 1,025,455 - 1,037,339 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 989,277 - 1,001,734 (+) NCBI T2T-CHM13v2.0
Cnn2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 10 79,824,434 - 79,831,234 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 10 79,824,418 - 79,831,896 (+) Ensembl GRCm39 Ensembl GRCm38 10 79,988,600 - 79,995,400 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 10 79,988,584 - 79,996,062 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 10 79,451,345 - 79,458,145 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 10 79,391,763 - 79,398,518 (+) NCBI MGSCv36 mm8 Celera 10 81,003,407 - 81,010,207 (+) NCBI Celera Cytogenetic Map 10 C1 NCBI cM Map 10 39.72 NCBI
Cnn2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955495 6,839,436 - 6,848,207 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955495 6,839,436 - 6,848,208 (-) NCBI ChiLan1.0 ChiLan1.0
CNN2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 5,356,334 - 5,373,918 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 4,595,936 - 4,610,232 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 10 40,502,394 - 40,504,543 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 1,005,670 - 1,015,133 (+) NCBI panpan1.1 PanPan1.1 panPan2
CNN2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 20 57,684,959 - 57,691,621 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 20 57,637,796 - 57,691,896 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 20 57,487,080 - 57,493,718 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 20 58,426,988 - 58,433,632 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 20 58,426,991 - 58,433,910 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 20 57,482,356 - 57,488,965 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 20 57,961,891 - 57,968,481 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 20 58,164,870 - 58,171,514 (-) NCBI UU_Cfam_GSD_1.0
Cnn2
CNN2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 2 77,375,983 - 77,385,571 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 2 77,376,020 - 77,385,594 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 2 77,612,076 - 77,621,630 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
CNN2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Vero_WHO_p1.0 NW_023666081 8,122,406 - 8,139,092 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Cnn2
.
Predicted Target Of
Count of predictions: 106 Count of miRNA genes: 88 Interacting mature miRNAs: 93 Transcripts: ENSRNOT00000065093 Prediction methods: Microtar, Rnahybrid Result types: miRGate_prediction
61410 Bw19 Body weight QTL 19 6.2 0.001 body mass (VT:0001259) body weight (CMO:0000012) 7 1 44782185 Rat 1300176 Hrtrt10 Heart rate QTL 10 3.19 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 7 664270 26029351 Rat 9590102 Sffal5 Serum free fatty acids level QTL 5 8.62 0.001 blood free fatty acid amount (VT:0001553) plasma free fatty acids level (CMO:0000546) 7 5329019 50329019 Rat 1643004 Pain2 Pain QTL 2 1 mechanical nociception trait (VT:0002734) self mutilation severity score (CMO:0002145) 7 9462246 98011544 Rat 631503 Bp102 Blood pressure QTL 102 1.9 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 7 1 44822433 Rat 634336 Anxrr17 Anxiety related response QTL 17 3.66 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 7 924703 115097879 Rat 10755438 Coatc9 Coat color QTL 9 0 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 7 3529280 48529280 Rat 9590142 Scort5 Serum corticosterone level QTL 5 24.4 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 7 1 31962314 Rat 2298547 Neuinf5 Neuroinflammation QTL 5 3.7 nervous system integrity trait (VT:0010566) spinal cord Cd74 protein level (CMO:0002131) 7 9462246 58265113 Rat 10059592 Kidm45 Kidney mass QTL 45 3.95 0.025 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 7 7573985 52573985 Rat 2317047 Wbc4 White blood cell count QTL 4 0.01 leukocyte quantity (VT:0000217) white blood cell count (CMO:0000027) 7 1 35342956 Rat 10755440 Coatc10 Coat color QTL 10 0 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 7 7496499 52496499 Rat 2298550 Neuinf6 Neuroinflammation QTL 6 3.3 nervous system integrity trait (VT:0010566) spinal cord RT1-B protein level (CMO:0002132) 7 1 27829089 Rat 724560 Plsm3 Polydactyly-luxate syndrome (PLS) morphotypes QTL 3 0.0003 tibia length (VT:0004357) tibia length (CMO:0000450) 7 1 34000259 Rat 7411566 Bw136 Body weight QTL 136 10.4 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 7 1 31962314 Rat
RH127486
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 7 9,712,644 - 9,712,846 (+) MAPPER mRatBN7.2 Rnor_6.0 7 12,763,622 - 12,763,823 NCBI Rnor6.0 Rnor_5.0 7 12,933,344 - 12,933,545 UniSTS Rnor5.0 RGSC_v3.4 7 11,225,323 - 11,225,524 UniSTS RGSC3.4 Celera 7 7,888,321 - 7,888,522 UniSTS RH 3.4 Map 7 25.2 UniSTS Cytogenetic Map 7 q11 UniSTS
RH131872
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 7 9,720,615 - 9,720,813 (-) MAPPER mRatBN7.2 Rnor_6.0 7 12,781,358 - 12,781,555 NCBI Rnor6.0 Rnor_5.0 7 12,951,080 - 12,951,277 UniSTS Rnor5.0 Celera 7 7,896,219 - 7,896,416 UniSTS RH 3.4 Map 7 25.6 UniSTS Cytogenetic Map 7 q11 UniSTS
RH139166
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 7 9,713,029 - 9,713,169 (+) MAPPER mRatBN7.2 Rnor_6.0 7 12,764,007 - 12,764,146 NCBI Rnor6.0 Rnor_5.0 7 12,933,729 - 12,933,868 UniSTS Rnor5.0 RGSC_v3.4 7 11,225,708 - 11,225,847 UniSTS RGSC3.4 Celera 7 7,888,706 - 7,888,845 UniSTS Cytogenetic Map 7 q11 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000065093 ⟹ ENSRNOP00000063042
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 7 9,712,516 - 9,719,656 (-) Ensembl Rnor_6.0 Ensembl 7 12,782,491 - 12,787,750 (+) Ensembl
RefSeq Acc Id:
NM_001399010 ⟹ NP_001385939
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 7 10,363,141 - 10,370,312 (-) NCBI mRatBN7.2 7 9,712,505 - 9,719,678 (-) NCBI
Ensembl Acc Id:
ENSRNOP00000063042 ⟸ ENSRNOT00000065093
RefSeq Acc Id:
NP_001385939 ⟸ NM_001399010
RGD ID: 13695052 Promoter ID: EPDNEW_R5574 Type: initiation region Name: Cnn2_1 Description: calponin 2 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 7 12,782,489 - 12,782,549 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2013-11-22
Cnn2
calponin 2
LOC690976
similar to Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2006-11-20
LOC690976
similar to Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Symbol and Name status set to provisional
70820 PROVISIONAL
