CNN2 (calponin 2) - Rat Genome Database

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Gene: CNN2 (calponin 2) Chlorocebus sabaeus
Analyze
Symbol: CNN2
Name: calponin 2
RGD ID: 18590905
Description: ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calmodulin binding (inferred); INVOLVED IN cellular response to mechanical stimulus (ortholog); establishment of localization in cell (ortholog); hemopoiesis (ortholog); ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); cyclic hematopoiesis (ortholog); Peutz-Jeghers syndrome (ortholog); FOUND IN stress fiber (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calponin-2; LOC103247818; uncharacterized LOC103247818
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660818,122,406 - 8,139,092 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CNN2Green Monkeycerebral creatine deficiency syndrome  ISOCNN2 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebral creatine deficiency syndromeClinVarPMID:28492532
CNN2Green Monkeycyclic hematopoiesis  ISOCNN2 (Homo sapiens)8554872ClinVar Annotator: match by term: Cyclical neutropeniaClinVarPMID:28492532
CNN2Green MonkeyPeutz-Jeghers syndrome  ISOCNN2 (Homo sapiens)8554872ClinVar Annotator: match by term: Peutz-Jeghers syndromeClinVarPMID:14970844 more ...
CNN2Green MonkeyPulmonary Atresia  ISOCNN2 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary artery atresiaClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CNN2Green Monkeyrenal cell carcinoma  ISOCNN2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15108329


Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CNN2Green Monkeyactin filament organization involved_inIEAPANTHER:PTN009209734150520179 TreeGrafterGO_REF:0000118
CNN2Green Monkeyactomyosin structure organization involved_inIEAInterPro:IPR001997150520179 InterProGO_REF:0000002
CNN2Green Monkeycellular response to mechanical stimulus acts_upstream_of_or_withinISOCNN2 (Homo sapiens)9068941 PMID:16236705MGIPMID:16236705
CNN2Green Monkeyestablishment of localization in cell acts_upstream_ofISOMGI:38204229068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeyhemopoiesis acts_upstream_of_or_withinISOMGI:38204239068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeymacrophage migration acts_upstream_ofISOMGI:38204229068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeynegative regulation of macrophage migration acts_upstream_of_or_withinISOMGI:38204229068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeynegative regulation of phagocytosis acts_upstream_of_or_withinISOMGI:38204229068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeyphagocytosis acts_upstream_ofISOMGI:38204229068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeypositive regulation of gene expression acts_upstream_of_or_withinISOMGI:38204239068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeyregulation of actin filament-based process acts_upstream_of_or_withinISOCNN2 (Homo sapiens)9068941 PMID:16236705MGIPMID:16236705
CNN2Green Monkeyregulation of leukocyte proliferation acts_upstream_of_or_withinISOMGI:3820421 more ...9068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeyregulation of mononuclear cell proliferation acts_upstream_of_or_withinISOMGI:3820421 more ...9068941 PMID:18617524MGIPMID:18617524
CNN2Green Monkeywound healing acts_upstream_of_or_withinISOMGI:38204239068941 PMID:18617524MGIPMID:18617524
1 to 14 of 14 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CNN2Green Monkeyactin cytoskeleton located_inIEAPANTHER:PTN009209734150520179 TreeGrafterGO_REF:0000118
CNN2Green Monkeyfocal adhesion located_inIEAPANTHER:PTN009209734150520179 TreeGrafterGO_REF:0000118
CNN2Green Monkeystress fiber located_inISOCNN2 (Homo sapiens)9068941 PMID:16236705MGIPMID:16236705

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CNN2Green Monkeyactin binding enablesIEAInterPro:IPR001997150520179 InterProGO_REF:0000002
CNN2Green Monkeyactin binding enablesIEAUniProtKB-KW:KW-0009150520179 UniProtGO_REF:0000043
CNN2Green Monkeyactin filament binding enablesIEAPANTHER:PTN009209734150520179 TreeGrafterGO_REF:0000118
CNN2Green Monkeycalmodulin binding enablesIEAUniProtKB-KW:KW-0112150520179 UniProtGO_REF:0000043

PMID:22301074  



CNN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660818,122,406 - 8,139,092 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CNN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,026,608 - 1,039,065 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,026,586 - 1,039,068 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,026,607 - 1,039,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619977,298 - 990,064 (+)NCBINCBI36Build 36hg18NCBI36
Build 3419977,297 - 990,063NCBI
Celera19958,638 - 969,897 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19799,427 - 811,654 (+)NCBIHuRef
CHM1_1191,025,455 - 1,037,339 (+)NCBICHM1_1
T2T-CHM13v2.019989,277 - 1,001,734 (+)NCBIT2T-CHM13v2.0
Cnn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,824,434 - 79,831,234 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,824,418 - 79,831,896 (+)EnsemblGRCm39 Ensembl
GRCm381079,988,600 - 79,995,400 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,988,584 - 79,996,062 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,451,345 - 79,458,145 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,391,763 - 79,398,518 (+)NCBIMGSCv36mm8
Celera1081,003,407 - 81,010,207 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Cnn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,363,141 - 10,370,312 (-)NCBIGRCr8
mRatBN7.279,712,505 - 9,719,678 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,712,516 - 9,719,656 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,594,690 - 12,601,905 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,470,026 - 14,477,227 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,331,153 - 12,338,424 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,782,459 - 12,787,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,782,491 - 12,787,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,952,193 - 12,957,718 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,223,451 - 11,232,524 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera77,888,183 - 7,895,312 (-)NCBICelera
Cytogenetic Map7q11NCBI
Cnn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,839,436 - 6,848,207 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,839,436 - 6,848,208 (-)NCBIChiLan1.0ChiLan1.0
CNN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,356,334 - 5,373,918 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,595,936 - 4,610,232 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01040,502,394 - 40,504,543 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1191,005,670 - 1,015,133 (+)NCBIpanpan1.1PanPan1.1panPan2
CNN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,684,959 - 57,691,621 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,637,796 - 57,691,896 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,487,080 - 57,493,718 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,426,988 - 58,433,632 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,426,991 - 58,433,910 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,482,356 - 57,488,965 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,961,891 - 57,968,481 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,164,870 - 58,171,514 (-)NCBIUU_Cfam_GSD_1.0
Cnn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,375,132 - 217,380,885 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588453,876 - 460,015 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588453,908 - 459,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,375,983 - 77,385,571 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,376,020 - 77,385,594 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,612,076 - 77,621,630 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cnn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,593,116 - 7,601,680 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,594,995 - 7,601,639 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.
RefSeq Transcripts XM_037994560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_037994560   ⟹   XP_037850488
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660818,122,406 - 8,139,092 (-)NCBI
Protein RefSeqs XP_037850488 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_037850488   ⟸   XM_037994560
- UniProtKB: A0A0D9SC47 (UniProtKB/TrEMBL)



Database
Acc Id
Source(s)
NCBI Gene LOC103247818 ENTREZGENE
UniProt A0A0D9SC47 ENTREZGENE


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 CNN2  calponin 2  LOC103247818  uncharacterized LOC103247818  Symbol and/or name change 5135510 APPROVED