Pinx1 (PIN2/TERF1 interacting, telomerase inhibitor 1) - Rat Genome Database

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Gene: Pinx1 (PIN2/TERF1 interacting, telomerase inhibitor 1) Rattus norvegicus
Analyze
Symbol: Pinx1
Name: PIN2/TERF1 interacting, telomerase inhibitor 1
RGD ID: 1566025
Description: Predicted to enable telomerase RNA binding activity and telomerase inhibitor activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of protein localization to nucleolus; and protein localization to organelle. Predicted to act upstream of or within telomere maintenance via telomerase. Predicted to be located in several cellular components, including chromosome; nucleoplasm; and spindle. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305963; PIN2-interacting protein 1; Pin2-interacting protein X1; PIN2/TERF1-interacting telomerase inhibitor 1; RGD1566025; similar to Pin2-interacting protein X1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81542,273,805 - 42,333,047 (+)NCBIGRCr8
mRatBN7.21538,097,896 - 38,157,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1538,097,886 - 38,157,140 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1539,955,508 - 40,014,259 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01541,106,199 - 41,164,948 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,558,617 - 39,617,496 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01547,211,682 - 47,270,343 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1547,211,583 - 47,270,317 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01550,970,703 - 51,029,737 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41543,124,973 - 43,184,374 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1537,779,927 - 37,838,591 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Pinx1Rathepatocellular carcinoma disease_progressionISOPINX1 (Homo sapiens)152977752associated with Chronic Hepatitis B and DNA:SNP::rs1469557(human)RGD 
Object Symbol
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Original Reference(s)
Pinx1RatNeurodevelopmental Disorders  ISOPINX1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pinx1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PINX1 mRNA]CTDPMID:31150632
Pinx1Rat1,2-dimethylhydrazine increases expressionISOPinx1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PINX1 mRNACTDPMID:22206623
Pinx1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PINX1 mRNACTDPMID:32145629
Pinx1Rat17beta-estradiol increases expressionISOPINX1 (Homo sapiens)6480464Estradiol results in increased expression of PINX1 mRNACTDPMID:31614463
Pinx1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPinx1 (Mus musculus)6480464AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PINX1 mRNA]CTDPMID:15034205
Pinx1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PINX1 mRNACTDPMID:33387578
Pinx1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPinx1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PINX1 mRNACTDPMID:15034205
Pinx1Ratarsenous acid decreases expressionISOPINX1 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of PINX1 mRNACTDPMID:22944098
Pinx1Ratatrazine decreases expressionISOPINX1 (Homo sapiens)6480464Atrazine results in decreased expression of PINX1 mRNACTDPMID:22378314
Pinx1Ratbenzo[a]pyrene multiple interactionsISOPinx1 (Mus musculus)6480464[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PINX1 mRNA and AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of PINX1 mRNA]CTDPMID:15034205 and PMID:27858113
Pinx1Ratbenzo[a]pyrene affects methylationISOPINX1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of PINX1 intronCTDPMID:30157460
Pinx1Ratbenzo[a]pyrene increases expressionISOPinx1 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of PINX1 mRNACTDPMID:15034205
Pinx1Ratbenzo[b]fluoranthene multiple interactionsISOPinx1 (Mus musculus)6480464[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PINX1 mRNACTDPMID:27858113
Pinx1Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of PINX1 mRNACTDPMID:25181051
Pinx1Ratbisphenol A multiple interactionsISOPINX1 (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in decreased methylation of PINX1 geneCTDPMID:31601247
Pinx1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of PINX1 mRNACTDPMID:32145629 and PMID:34947998
Pinx1Ratbisphenol F decreases expressionISOPinx1 (Mus musculus)6480464bisphenol F results in decreased expression of PINX1 mRNACTDPMID:38685157
Pinx1Ratbutanal increases expressionISOPINX1 (Homo sapiens)6480464butyraldehyde results in increased expression of PINX1 mRNACTDPMID:26079696
Pinx1Ratcadmium dichloride decreases expressionISOPINX1 (Homo sapiens)6480464Cadmium Chloride results in decreased expression of PINX1 mRNACTDPMID:38382870
Pinx1Ratcadmium dichloride increases expressionISOPINX1 (Homo sapiens)6480464Cadmium Chloride results in increased expression of PINX1 mRNACTDPMID:38568856

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Biological Process
1 to 18 of 18 rows

  
Object Symbol
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Original Reference(s)
Pinx1Ratmitotic metaphase chromosome alignment involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratmitotic metaphase chromosome alignment involved_inISOPINX1 (Homo sapiens)1624291 PMID:19393617RGDPMID:19393617
Pinx1Ratnegative regulation of G2/M transition of mitotic cell cycle involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratnegative regulation of G2/M transition of mitotic cell cycle involved_inISOPINX1 (Homo sapiens)1624291 PMID:11701125RGDPMID:11701125
Pinx1Ratnegative regulation of protein ubiquitination involved_inISOPINX1 (Homo sapiens)1624291 PMID:24415760RGDPMID:24415760
Pinx1Ratnegative regulation of protein ubiquitination involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratnegative regulation of telomere maintenance via telomerase involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratnegative regulation of telomere maintenance via telomerase involved_inISOPINX1 (Homo sapiens)1624291 PMID:11701125 and PMID:21119197RGDPMID:11701125 and PMID:21119197
Pinx1Ratpositive regulation of protein localization to nucleolus involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratpositive regulation of protein localization to nucleolus involved_inISOPINX1 (Homo sapiens)1624291 PMID:19265708RGDPMID:19265708
Pinx1Ratprotein localization to chromosome, telomeric region involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratprotein localization to chromosome, telomeric region involved_inISOPINX1 (Homo sapiens)1624291 PMID:22749911RGDPMID:22749911
Pinx1Ratprotein localization to nucleolus involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratprotein localization to nucleolus involved_inISOPINX1 (Homo sapiens)1624291 PMID:24415760RGDPMID:24415760
Pinx1Ratregulation of protein stability involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratregulation of protein stability involved_inISOPINX1 (Homo sapiens)1624291 PMID:24415760RGDPMID:24415760
Pinx1Rattelomere maintenance via telomerase acts_upstream_of_or_withinISOPINX1 (Homo sapiens)1624291 PMID:11701125RGDPMID:11701125
Pinx1Rattelomere maintenance via telomerase involved_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 16 of 16 rows

  
Object Symbol
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Reference
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Source
Original Reference(s)
Pinx1Ratchromosome, telomeric region located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratchromosome, telomeric region located_inISOPINX1 (Homo sapiens)1624291 PMID:11701125 more ...RGDPMID:11701125 more ...
Pinx1Ratkinetochore located_inISOPINX1 (Homo sapiens)1624291 PMID:19393617RGDPMID:19393617
Pinx1Ratkinetochore located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratmitochondrion located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratmitochondrion located_inISOPINX1 (Homo sapiens) and UniProtKB:Q96BK5-11624291 RGDGO_REF:0000052
Pinx1Ratnuclear chromosome located_inISOPINX1 (Homo sapiens)1624291 PMID:19393617RGDPMID:19393617
Pinx1Ratnuclear chromosome located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratnucleolus located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratnucleolus located_inISOPINX1 (Homo sapiens)1624291 PMID:11701125 more ...RGDPMID:11701125 more ...
Pinx1Ratnucleolus is_active_inIBAPANTHER:PTN000567695 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pinx1Ratnucleolus located_inISOPINX1 (Homo sapiens) and UniProtKB:Q96BK5-11624291 RGDGO_REF:0000052
Pinx1Ratnucleoplasm located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratnucleoplasm located_inISOPINX1 (Homo sapiens) and UniProtKB:Q96BK5-11624291 RGDGO_REF:0000052
Pinx1Ratspindle located_inISOPINX1 (Homo sapiens)1624291 PMID:19393617RGDPMID:19393617
Pinx1Ratspindle located_inIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function

  
Object Symbol
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Reference
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Original Reference(s)
Pinx1Ratprotein binding enablesISOPINX1 (Homo sapiens)1624291UniProtKB:O14746 more ...RGDPMID:11701125 more ...
Pinx1Ratprotein-containing complex binding enablesIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Ratprotein-containing complex binding enablesISOPINX1 (Homo sapiens)1624291ComplexPortal:CPX-152 PMID:18202258RGDPMID:18202258
Pinx1Rattelomerase inhibitor activity enablesIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Rattelomerase inhibitor activity enablesIBAPANTHER:PTN001139619 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pinx1Rattelomerase inhibitor activity enablesISOPINX1 (Homo sapiens)1624291 PMID:11701125 and PMID:21119197RGDPMID:11701125 and PMID:21119197
Pinx1Rattelomerase RNA binding enablesIEAUniProtKB:Q96BK5 and ensembl:ENSP000003189661600115GO_REF:0000107EnsemblGO_REF:0000107
Pinx1Rattelomerase RNA binding enablesISOPINX1 (Homo sapiens)1624291 PMID:15381700RGDPMID:15381700


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Association of PINX1 but not TEP1 Polymorphisms with Progression to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection. Sriprapun M, etal., Asian Pac J Cancer Prev. 2016;17(4):2019-25. doi: 10.7314/apjcp.2016.17.4.2019.
PMID:11701125   PMID:12477932   PMID:15381700   PMID:17624691   PMID:18202258   PMID:19265708   PMID:19393617   PMID:21119197   PMID:22749911   PMID:24415760   PMID:33819185  



Pinx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81542,273,805 - 42,333,047 (+)NCBIGRCr8
mRatBN7.21538,097,896 - 38,157,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1538,097,886 - 38,157,140 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1539,955,508 - 40,014,259 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01541,106,199 - 41,164,948 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,558,617 - 39,617,496 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01547,211,682 - 47,270,343 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1547,211,583 - 47,270,317 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01550,970,703 - 51,029,737 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41543,124,973 - 43,184,374 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1537,779,927 - 37,838,591 (+)NCBICelera
Cytogenetic Map15p12NCBI
PINX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38810,764,961 - 10,839,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl810,725,399 - 10,839,847 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl810,764,961 - 10,839,884 (-)EnsemblGRCh38hg38GRCh38
GRCh37810,622,471 - 10,697,385 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36810,660,294 - 10,734,709 (-)NCBINCBI36Build 36hg18NCBI36
Celera89,750,922 - 9,825,196 (-)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef89,553,144 - 9,627,372 (-)NCBIHuRef
CHM1_1810,688,381 - 10,762,380 (-)NCBICHM1_1
T2T-CHM13v2.088,899,172 - 8,974,128 (+)NCBIT2T-CHM13v2.0
Pinx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391464,097,728 - 64,157,311 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1464,097,813 - 64,157,308 (+)EnsemblGRCm39 Ensembl
GRCm381463,860,277 - 63,919,862 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1463,860,364 - 63,919,859 (+)EnsemblGRCm38mm10GRCm38
MGSCv371464,479,149 - 64,538,696 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361462,814,474 - 62,873,914 (+)NCBIMGSCv36mm8
Celera1461,637,517 - 61,696,912 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.34NCBI
Pinx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540352,284,166 - 52,362,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540352,284,378 - 52,361,924 (-)NCBIChiLan1.0ChiLan1.0
PINX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2727,220,919 - 27,297,382 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan183,253,071 - 3,329,606 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v088,366,819 - 8,443,359 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PINX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12527,090,244 - 27,182,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2527,021,704 - 27,181,968 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2527,746,795 - 27,839,000 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02527,245,097 - 27,337,408 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2527,244,824 - 27,336,999 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12527,199,192 - 27,291,630 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02527,093,374 - 27,185,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02527,247,284 - 27,339,666 (+)NCBIUU_Cfam_GSD_1.0
Pinx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049435,879,927 - 5,944,300 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366752,640,068 - 2,706,238 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366752,641,851 - 2,706,201 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PINX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1413,967,070 - 14,041,788 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11413,965,733 - 14,041,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21415,432,132 - 15,483,040 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PINX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.188,259,537 - 8,336,586 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl88,259,692 - 8,336,603 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605234,091,837 - 34,171,496 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pinx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475824,589,743 - 24,666,598 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475824,589,990 - 24,666,355 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pinx1
366 total Variants

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:51
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000016027
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 27 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat

1 to 10 of 27 rows
RH128783  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,156,801 - 38,157,021 (+)MAPPERmRatBN7.2
Rnor_6.01547,270,002 - 47,270,221NCBIRnor6.0
Rnor_5.01551,029,396 - 51,029,615UniSTSRnor5.0
RGSC_v3.41543,184,268 - 43,184,487UniSTSRGSC3.4
Celera1537,838,485 - 37,838,704UniSTS
Cytogenetic Map15p12UniSTS
RH132666  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,144,331 - 38,144,527 (+)MAPPERmRatBN7.2
Rnor_6.01547,258,112 - 47,258,307NCBIRnor6.0
Rnor_5.01551,017,506 - 51,017,701UniSTSRnor5.0
RGSC_v3.41543,171,798 - 43,171,993UniSTSRGSC3.4
Celera1537,826,007 - 37,826,202UniSTS
Cytogenetic Map15p12UniSTS
BQ195852  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,116,239 - 38,116,454 (+)MAPPERmRatBN7.2
Rnor_6.01547,229,722 - 47,229,936NCBIRnor6.0
Rnor_5.01550,989,116 - 50,989,330UniSTSRnor5.0
RGSC_v3.41543,143,541 - 43,143,755UniSTSRGSC3.4
Celera1537,798,008 - 37,798,222UniSTS
RH 3.4 Map15282.4UniSTS
Cytogenetic Map15p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000016027   ⟹   ENSRNOP00000016027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,097,886 - 38,157,130 (+)Ensembl
Rnor_6.0 Ensembl1547,211,583 - 47,270,317 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102140   ⟹   ENSRNOP00000085367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,098,756 - 38,157,140 (+)Ensembl
RefSeq Acc Id: NM_001083337   ⟹   NP_001076806
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,273,805 - 42,333,047 (+)NCBI
mRatBN7.21538,097,896 - 38,157,143 (+)NCBI
Rnor_6.01547,211,682 - 47,270,108 (+)NCBI
Rnor_5.01550,970,703 - 51,029,737 (+)NCBI
RGSC_v3.41543,124,973 - 43,184,374 (+)RGD
Celera1537,779,927 - 37,838,591 (+)RGD
Sequence:
RefSeq Acc Id: XM_006252181   ⟹   XP_006252243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,277,104 - 42,333,047 (+)NCBI
mRatBN7.21538,100,334 - 38,157,143 (+)NCBI
Rnor_6.01547,213,876 - 47,270,343 (+)NCBI
Rnor_5.01550,970,703 - 51,029,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093329   ⟹   XP_038949257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,277,104 - 42,292,661 (+)NCBI
mRatBN7.21538,100,334 - 38,116,756 (+)NCBI
RefSeq Acc Id: XM_039093331   ⟹   XP_038949259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,277,104 - 42,333,047 (+)NCBI
mRatBN7.21538,100,334 - 38,156,547 (+)NCBI
RefSeq Acc Id: XM_063274286   ⟹   XP_063130356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,273,814 - 42,292,661 (+)NCBI
RefSeq Acc Id: XR_010057820
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,277,104 - 42,332,518 (+)NCBI
RefSeq Acc Id: XR_010057821
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,277,104 - 42,332,518 (+)NCBI
RefSeq Acc Id: XR_010057822
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,273,814 - 42,332,518 (+)NCBI
RefSeq Acc Id: NP_001076806   ⟸   NM_001083337
- UniProtKB: A4L691 (UniProtKB/Swiss-Prot),   B0BMT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252243   ⟸   XM_006252181
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A1H3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016027   ⟸   ENSRNOT00000016027
RefSeq Acc Id: XP_038949259   ⟸   XM_039093331
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038949257   ⟸   XM_039093329
- Peptide Label: isoform X2
G-patch

Name Modeler Protein Id AA Range Protein Structure
AF-A4L691-F1-model_v2 AlphaFold A4L691 1-331 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699781
Promoter ID:EPDNEW_R10303
Type:initiation region
Name:Pinx1_1
Description:PIN2/TERF1 interacting, telomerase inhibitor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01547,211,575 - 47,211,635EPDNEW


1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-13403 BioCyc
Ensembl Genes ENSRNOG00000012012 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016027.6 UniProtKB/Swiss-Prot
  ENSRNOT00000102140.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9088212 IMAGE-MGC_LOAD
InterPro G_patch_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PINX1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:305963 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:187218 IMAGE-MGC_LOAD
NCBI Gene 305963 ENTREZGENE
PANTHER G PATCH DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIN2/TERF1-INTERACTING TELOMERASE INHIBITOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam G-patch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pinx1 PhenoGen
PROSITE G_PATCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012012 RatGTEx
SMART G_patch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A1H3 ENTREZGENE, UniProtKB/TrEMBL
  A4L691 ENTREZGENE
  B0BMT3 ENTREZGENE, UniProtKB/TrEMBL
  PINX1_RAT UniProtKB/Swiss-Prot
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Pinx1  PIN2/TERF1 interacting, telomerase inhibitor 1  Pinx1  PIN2-interacting protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Pinx1  PIN2-interacting protein 1  RGD1566025_predicted  similar to Pin2-interacting protein X1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1566025_predicted  similar to Pin2-interacting protein X1 (predicted)  LOC305963  similar to Pin2-interacting protein X1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC305963  similar to Pin2-interacting protein X1      Symbol and Name status set to provisional 70820 PROVISIONAL