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Gene: PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1) Homo sapiens
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Symbol: PINX1
Name: PIN2 (TERF1) interacting telomerase inhibitor 1
Description: Exhibits telomerase RNA binding activity and telomerase inhibitor activity. Involved in several processes, including chromosome organization; negative regulation of DNA biosynthetic process; and protein localization to organelle. Localizes to kinetochore; nuclear lumen; and spindle; INTERACTS WITH arsenous acid; atrazine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 67-11-3 protein; FLJ20565; Gno1; hepatocellular carcinoma-related putative tumor suppressor; liver-related putative tumor suppressor; LPTL; LPTS; MGC8850; PIN2 interacting protein 1; PIN2-interacting protein 1; pin2-interacting protein X1; PIN2/TERF1 interacting telomerase inhibitor 1; PIN2/TERF1 interacting, telomerase inhibitor 1; PIN2/TERF1-interacting telomerase inhibitor 1; protein 67-11-3; Pxr1; TRF1-interacting protein 1
Orthologs:
Mus musculus (house mouse) : Pinx1 (PIN2/TERF1 interacting, telomerase inhibitor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pinx1 (PIN2/TERF1 interacting, telomerase inhibitor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pinx1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Canis lupus familiaris (dog) : PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pinx1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Sus scrofa (pig) : PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Chlorocebus sabaeus (African green monkey) : PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
Heterocephalus glaber (naked mole-rat) : Pinx1 (PIN2 (TERF1) interacting telomerase inhibitor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl810,725,399 - 10,839,847 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl810,764,961 - 10,839,884 (-)EnsemblGRCh38hg38GRCh38
GRCh38810,764,961 - 10,839,899 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37810,622,473 - 10,697,394 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36810,660,294 - 10,734,709 (-)NCBINCBI36hg18NCBI36
Celera89,750,922 - 9,825,196 (-)NCBI
Cytogenetic Map8p23.1NCBI
HuRef89,553,144 - 9,627,372 (-)NCBIHuRef
CHM1_1810,687,968 - 10,762,490 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PINX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606271
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.