Diras3 (DIRAS family GTPase 3) - Rat Genome Database

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Gene: Diras3 (DIRAS family GTPase 3) Rattus norvegicus
Analyze
Symbol: Diras3
Name: DIRAS family GTPase 3
RGD ID: 1565168
Description: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be located in endomembrane system. Predicted to be active in plasma membrane. Orthologous to human DIRAS3 (DIRAS family GTPase 3); INTERACTS WITH alpha-Zearalanol; Cuprizon; doxorubicin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DIRAS family, GTP-binding RAS-like 3; LOC366733; ras-related protein Rap-2a-like; RGD1565168; similar to RAP2A, member of RAS oncogene family
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,346,157 - 136,347,371 (-)NCBIGRCr8
mRatBN7.26130,524,972 - 130,526,186 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,524,742 - 130,530,825 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06135,938,345 - 135,940,205 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,938,935 - 135,939,534 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,475,515 - 144,477,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,245,520 - 136,247,072 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6128,080,876 - 128,082,770 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Diras3Ratintellectual disability  ISODIRAS3 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and severeClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Diras3Rathepatocellular carcinoma  ISODIRAS3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560

1 to 20 of 47 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Diras3Rat17beta-estradiol affects expressionISODIRAS3 (Homo sapiens)6480464Estradiol affects the expression of DIRAS3 mRNACTDPMID:20106945
Diras3Rat17beta-estradiol increases expressionISODIRAS3 (Homo sapiens)6480464Estradiol results in increased expression of DIRAS3 mRNACTDPMID:36828454
Diras3Rat2-palmitoylglycerol increases expressionISODIRAS3 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of DIRAS3 mRNACTDPMID:37199045
Diras3Rataflatoxin B1 affects expressionISODIRAS3 (Homo sapiens)6480464Aflatoxin B1 affects the expression of DIRAS3 proteinCTDPMID:20106945
Diras3Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of DIRAS3 mRNACTDPMID:35163327
Diras3RatArchazolid B decreases expressionISODIRAS3 (Homo sapiens)6480464archazolid B results in decreased expression of DIRAS3 mRNACTDPMID:25218289
Diras3Rataristolochic acid A decreases expressionISODIRAS3 (Homo sapiens)6480464aristolochic acid I results in decreased expression of DIRAS3 mRNACTDPMID:33212167
Diras3Ratarsenite(3-) increases methylationISODIRAS3 (Homo sapiens)6480464arsenite results in increased methylation of DIRAS3 promoterCTDPMID:23974009
Diras3Ratarsenous acid decreases expressionISODIRAS3 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of DIRAS3 mRNACTDPMID:26705709
Diras3Ratbenzo[a]pyrene decreases methylationISODIRAS3 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of DIRAS3 exonCTDPMID:27901495
Diras3Ratbenzo[a]pyrene decreases expressionISODIRAS3 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of DIRAS3 mRNACTDPMID:32234424
Diras3Ratbenzo[a]pyrene affects methylationISODIRAS3 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of DIRAS3 5' UTR and Benzo(a)pyrene affects the methylation of DIRAS3 promoterCTDPMID:27901495
Diras3Ratbisphenol A increases expressionISODIRAS3 (Homo sapiens)6480464bisphenol A results in increased expression of DIRAS3 mRNACTDPMID:27685785 and PMID:36828454
Diras3Ratbutanal decreases expressionISODIRAS3 (Homo sapiens)6480464butyraldehyde results in decreased expression of DIRAS3 mRNACTDPMID:26079696
Diras3RatCGP 52608 multiple interactionsISODIRAS3 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to DIRAS3 gene]CTDPMID:28238834
Diras3RatCuprizon decreases expressionEXP 6480464Cuprizone results in decreased expression of DIRAS3 mRNACTDPMID:26577399 and PMID:27523638
Diras3Ratcyclosporin A decreases expressionISODIRAS3 (Homo sapiens)6480464Cyclosporine results in decreased expression of DIRAS3 mRNACTDPMID:20106945
Diras3Ratdiarsenic trioxide decreases expressionISODIRAS3 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of DIRAS3 mRNACTDPMID:26705709
Diras3Ratdorsomorphin multiple interactionsISODIRAS3 (Homo sapiens)6480464[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...CTDPMID:27188386
Diras3Ratdoxorubicin decreases expressionEXP 6480464Doxorubicin results in decreased expression of DIRAS3 mRNACTDPMID:32289291

1 to 20 of 47 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Diras3Ratnegative regulation of cell migration involved_inIBAMGI:1919315 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Diras3RatRap protein signal transduction involved_inIBAMGI:1919315 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Diras3Ratsignal transduction involved_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Diras3Ratendomembrane system located_inIEAUniProtKB-SubCell:SL-01471600115GO_REF:0000044UniProtGO_REF:0000044
Diras3Ratmembrane located_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002
Diras3Ratplasma membrane is_active_inIBACGD:CAL0000184093 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Diras3RatGDP binding enablesIBAPANTHER:PTN000631348 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Diras3RatGTP binding enablesIBAMGI:108053 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Diras3RatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
Diras3RatGTP binding enablesIEAInterPro:IPR001806 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Diras3RatGTPase activity enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
Diras3RatGTPase activity enablesIBACGD:CAL0000181665 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Diras3Ratprotein binding enablesISODIRAS3 (Homo sapiens)1624291UniProtKB:P40763 more ...RGDPMID:21643014 and PMID:32296183


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:27903964  



Diras3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,346,157 - 136,347,371 (-)NCBIGRCr8
mRatBN7.26130,524,972 - 130,526,186 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,524,742 - 130,530,825 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06135,938,345 - 135,940,205 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,938,935 - 135,939,534 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,475,515 - 144,477,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,245,520 - 136,247,072 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6128,080,876 - 128,082,770 (-)NCBICelera
Cytogenetic Map6q32NCBI
DIRAS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38168,045,962 - 68,050,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl168,045,886 - 68,051,717 (-)EnsemblGRCh38hg38GRCh38
GRCh37168,511,645 - 68,516,310 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36168,284,233 - 68,289,048 (-)NCBINCBI36Build 36hg18NCBI36
Build 34168,223,667 - 68,228,481NCBI
Celera166,802,348 - 66,807,163 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef166,621,747 - 66,626,564 (-)NCBIHuRef
CHM1_1168,627,001 - 68,631,820 (-)NCBICHM1_1
T2T-CHM13v2.0167,923,423 - 67,928,086 (-)NCBIT2T-CHM13v2.0
Gm266
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,451,043 - 111,452,257 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,451,043 - 111,452,257 (-)EnsemblGRCm39 Ensembl
GRCm3812111,484,609 - 111,485,823 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,484,609 - 111,485,823 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712112,722,820 - 112,724,034 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,932,419 - 111,933,604 (-)NCBIMGSCv36mm8
Celera12112,674,808 - 112,676,022 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.01NCBI
DIRAS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21158,813,884 - 158,825,676 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11157,979,647 - 157,985,477 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0167,283,556 - 67,288,561 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1169,239,462 - 69,244,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl169,240,117 - 69,240,806 (-)Ensemblpanpan1.1panPan2
LOC480441
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,032,087 - 71,033,379 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,544,283 - 70,545,574 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0871,309,047 - 71,310,337 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1870,972,635 - 70,973,926 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0871,037,280 - 71,038,571 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,437,437 - 71,438,728 (-)NCBIUU_Cfam_GSD_1.0
Diras3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505880,798,207 - 80,800,867 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365913,688,774 - 3,691,342 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIRAS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6144,576,342 - 144,578,818 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16144,576,342 - 144,578,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26133,865,007 - 133,867,486 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DIRAS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12065,060,391 - 65,065,165 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2065,063,822 - 65,064,511 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603352,548,119 - 52,553,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Diras3
5 total Variants

1 to 10 of 207 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 Xp22.33-q28(chrX:10701-156003242)x3 copy number gain See cases [RCV000133911] ChrX:10701..156003242 [GRCh38]
ChrX:60701..155232907 [GRCh37]
ChrX:701..154886101 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic|likely pathogenic|conflicting data from submitters
GRCh38/hg38 Xp22.33-q28(chrX:3092486-155699618)x2 copy number gain See cases [RCV000050889] ChrX:3092486..155699618 [GRCh38]
ChrX:3010527..154929279 [GRCh37]
ChrX:3020527..154582473 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:20140-155699618)x3 copy number gain See cases [RCV000050810] ChrX:20140..155699618 [GRCh38]
ChrX:70140..154929279 [GRCh37]
ChrX:10140..154582473 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:20140-155699618)x1 copy number loss See cases [RCV000050811] ChrX:20140..155699618 [GRCh38]
ChrX:70140..154929279 [GRCh37]
ChrX:10140..154582473 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10679-156013167)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050385]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050385]|See cases [RCV000050385] ChrX:10679..156013167 [GRCh38]
ChrX:60679..155242832 [GRCh37]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10679-156013167)x1 copy number loss Global developmental delay [RCV000050386]|See cases [RCV000050386] ChrX:10679..156013167 [GRCh38]
ChrX:60679..155242832 [GRCh37]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10679-156022206)x3 copy number gain See cases [RCV000050697] ChrX:10679..156022206 [GRCh38]
ChrX:60679..155251871 [GRCh37]
ChrX:679..154905065 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 Xp22.33-q28(chrX:10679-156022206)x1 copy number loss See cases [RCV000050699] ChrX:10679..156022206 [GRCh38]
ChrX:60679..155251871 [GRCh37]
ChrX:679..154905065 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 Xp11.21-q28(chrX:57372584-155996431)x1 copy number loss See cases [RCV000051665] ChrX:57372584..155996431 [GRCh38]
ChrX:57399017..155226096 [GRCh37]
ChrX:57415742..154879290 [NCBI36]
ChrX:Xp11.21-q28		 pathogenic
GRCh38/hg38 Xq11.1-28(chrX:63279794-155939524)x1 copy number loss See cases [RCV000051666] ChrX:63279794..155939524 [GRCh38]
ChrX:62499671..155169188 [GRCh37]
ChrX:62416396..154822382 [NCBI36]
ChrX:Xq11.1-28		 pathogenic
1 to 10 of 207 rows

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:49
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000052237
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat

1 to 10 of 21 rows
RH133322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26130,525,110 - 130,525,325 (+)MAPPERmRatBN7.2
Rnor_6.06135,938,484 - 135,938,698NCBIRnor6.0
Rnor_5.06144,477,022 - 144,477,236UniSTSRnor5.0
RGSC_v3.46136,245,661 - 136,245,875UniSTSRGSC3.4
Celera6128,081,015 - 128,081,229UniSTS
RH 3.4 Map6782.4UniSTS
Cytogenetic Map6q32UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 107 90 89 58 25 58 6 217 97 87 45 60 31


RefSeq Transcripts NM_001408755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000052237   ⟹   ENSRNOP00000049780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6135,938,935 - 135,939,534 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117627   ⟹   ENSRNOP00000088755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6130,524,742 - 130,530,825 (-)Ensembl
RefSeq Acc Id: NM_001408755   ⟹   NP_001395684
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86136,346,157 - 136,347,371 (-)NCBI
mRatBN7.26130,524,972 - 130,526,186 (-)NCBI
Protein RefSeqs NP_001395684 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088755
  ENSRNOP00000088755.1
Ensembl Acc Id: ENSRNOP00000049780   ⟸   ENSRNOT00000052237
Ensembl Acc Id: ENSRNOP00000088755   ⟸   ENSRNOT00000117627
RefSeq Acc Id: NP_001395684   ⟸   NM_001408755
- UniProtKB: A0A8I6GGJ6 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-F1LX77-F1-model_v2 AlphaFold F1LX77 1-200 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694846
Promoter ID:EPDNEW_R5365
Type:single initiation site
Name:Diras3_1
Description:DIRAS family GTPase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06135,939,559 - 135,939,619EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-35846 BioCyc
Ensembl Genes ENSRNOG00000033736 Ensembl
  ENSRNOG00000068695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000117627 ENTREZGENE
  ENSRNOT00000117627.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
NCBI Gene 366733 ENTREZGENE
PANTHER PTHR24070 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PhenoGen Diras3 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033736 RatGTEx
  ENSRNOG00000068695 RatGTEx
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6GGJ6 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Diras3  DIRAS family GTPase 3  Diras3  DIRAS family GTPase 3  Data merged from RGD:149736355 737654 PROVISIONAL
2021-08-09 Diras3  DIRAS family GTPase 3      Symbol and Name status set to provisional 45752 PROVISIONAL
2016-05-11 Diras3  DIRAS family GTPase 3  Diras3  DIRAS family, GTP-binding RAS-like 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-28 Diras3  DIRAS family, GTP-binding RAS-like 3  RGD1565168  similar to RAP2A, member of RAS oncogene family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565168  similar to RAP2A, member of RAS oncogene family   RGD1565168_predicted  similar to RAP2A, member of RAS oncogene family (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565168_predicted  similar to RAP2A, member of RAS oncogene family (predicted)  LOC366733  similar to RAP2A, member of RAS oncogene family  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC366733  similar to RAP2A, member of RAS oncogene family      Symbol and Name status set to provisional 70820 PROVISIONAL