Gm266 (predicted gene 266) - Rat Genome Database

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Gene: Gm266 (predicted gene 266) Mus musculus
Analyze
Symbol: Gm266
Name: predicted gene 266
RGD ID: 1619015
MGI Page MGI
Description: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC212539; uncharacterized protein LOC212539
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,451,043 - 111,452,257 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,451,043 - 111,452,257 (-)EnsemblGRCm39 Ensembl
GRCm3812111,484,609 - 111,485,823 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,484,609 - 111,485,823 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712112,722,820 - 112,724,034 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,932,419 - 111,933,604 (-)NCBIMGSCv36mm8
Celera12112,674,808 - 112,676,022 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:19501082   PMID:21873635  


Genomics

Comparative Map Data
Gm266
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,451,043 - 111,452,257 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,451,043 - 111,452,257 (-)EnsemblGRCm39 Ensembl
GRCm3812111,484,609 - 111,485,823 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,484,609 - 111,485,823 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712112,722,820 - 112,724,034 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,932,419 - 111,933,604 (-)NCBIMGSCv36mm8
Celera12112,674,808 - 112,676,022 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.01NCBI
DIRAS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38168,045,962 - 68,050,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl168,045,886 - 68,051,717 (-)EnsemblGRCh38hg38GRCh38
GRCh37168,511,645 - 68,516,310 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36168,284,233 - 68,289,048 (-)NCBINCBI36Build 36hg18NCBI36
Build 34168,223,667 - 68,228,481NCBI
Celera166,802,348 - 66,807,163 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef166,621,747 - 66,626,564 (-)NCBIHuRef
CHM1_1168,627,001 - 68,631,820 (-)NCBICHM1_1
T2T-CHM13v2.0167,923,423 - 67,928,086 (-)NCBIT2T-CHM13v2.0
Diras3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,346,157 - 136,347,371 (-)NCBIGRCr8
mRatBN7.26130,524,972 - 130,526,186 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,524,742 - 130,530,825 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06135,938,345 - 135,940,205 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,938,935 - 135,939,534 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,475,515 - 144,477,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,245,520 - 136,247,072 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6128,080,876 - 128,082,770 (-)NCBICelera
Cytogenetic Map6q32NCBI
DIRAS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21158,813,884 - 158,825,676 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11157,979,647 - 157,985,477 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0167,283,556 - 67,288,561 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1169,239,462 - 69,244,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl169,240,117 - 69,240,806 (-)Ensemblpanpan1.1panPan2
LOC480441
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,032,087 - 71,033,379 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,544,283 - 70,545,574 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0871,309,047 - 71,310,337 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1870,972,635 - 70,973,926 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0871,037,280 - 71,038,571 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,437,437 - 71,438,728 (-)NCBIUU_Cfam_GSD_1.0
Diras3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505880,798,207 - 80,800,867 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365913,688,774 - 3,691,342 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIRAS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6144,576,342 - 144,578,818 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16144,576,342 - 144,578,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26133,865,007 - 133,867,486 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DIRAS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12065,060,391 - 65,065,165 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2065,063,822 - 65,064,511 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603352,548,119 - 52,553,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Gm266
34 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:203
Count of miRNA genes:168
Interacting mature miRNAs:187
Transcripts:ENSMUST00000010673
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
39128213Lwq23_mliver weight QTL 10 (mouse)1280956708113383533Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
4141297Plyid_mPolymeric IgA dominance (mouse)Not determined109183385115885122Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80956708113383533Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286396075114831653Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
13524842Ppiq10a_mprepulse inhibition QTL 10a (mouse)1277512220111512220Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80956708113383533Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
27226793Feml10_mfemur length 10, 5 week (mouse)1268346774113363620Mouse
1558957Igan4_mIgA nephropathy 4 (mouse)Not determined12109750025119024949Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80956708113383533Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1280989143114989143Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000010673   ⟹   ENSMUSP00000010673
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12111,451,043 - 111,452,257 (-)Ensembl
GRCm38.p6 Ensembl12111,484,609 - 111,485,823 (-)Ensembl
RefSeq Acc Id: NM_001033248   ⟹   NP_001028420
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912111,451,043 - 111,452,257 (-)NCBI
GRCm3812111,484,609 - 111,485,823 (-)ENTREZGENE
MGSCv3712112,722,820 - 112,724,034 (-)RGD
Celera12112,674,808 - 112,676,022 (-)RGD
cM Map12 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001028420 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI45737 (Get FASTA)   NCBI Sequence Viewer  
  AAI45763 (Get FASTA)   NCBI Sequence Viewer  
  BAE38750 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000010673
  ENSMUSP00000010673.6
RefSeq Acc Id: NP_001028420   ⟸   NM_001033248
- UniProtKB: A6H634 (UniProtKB/TrEMBL),   Q3TLP2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000010673   ⟸   ENSMUST00000010673

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6H634-F1-model_v2 AlphaFold A6H634 1-200 view protein structure

Promoters
RGD ID:8679328
Promoter ID:EPDNEW_M17695
Type:multiple initiation site
Name:Gm266_1
Description:Mus musculus predicted gene 266 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3812111,485,796 - 111,485,856EPDNEW
RGD ID:6822979
Promoter ID:MM_KWN:12829
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NM_001033248
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612112,723,741 - 112,724,292 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685112 AgrOrtholog
Ensembl Genes ENSMUSG00000010529 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000010673 ENTREZGENE
  ENSMUST00000010673.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras UniProtKB/TrEMBL
KEGG Report mmu:212539 UniProtKB/TrEMBL
MGD MGI:2685112 ENTREZGENE
NCBI Gene 212539 ENTREZGENE
PANTHER GENE MODEL 266, (NCBI) UniProtKB/TrEMBL
  PTHR24070 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PhenoGen Gm266 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A6H634 ENTREZGENE, UniProtKB/TrEMBL
  Q3TLP2 ENTREZGENE, UniProtKB/TrEMBL