Ube3c (ubiquitin protein ligase E3C) - Rat Genome Database

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Gene: Ube3c (ubiquitin protein ligase E3C) Rattus norvegicus
Analyze
Symbol: Ube3c
Name: ubiquitin protein ligase E3C
RGD ID: 1559986
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein K29-linked ubiquitination; protein K48-linked ubiquitination; and ubiquitin-dependent protein catabolic process. Orthologous to human UBE3C (ubiquitin protein ligase E3C); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362294; RGD1559986; similar to ubiquitin protein ligase E3C; ubiquitin-protein ligase E3C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr846,323,831 - 6,425,085 (-)NCBIGRCr8
mRatBN7.245,648,932 - 5,749,922 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl45,648,690 - 5,750,011 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.042,505,912 - 2,606,710 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl42,505,909 - 2,606,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.042,558,670 - 2,659,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44889,640 - 991,900 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera44,569,408 - 4,670,465 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube3cRatautistic disorder  ISOUBE3C (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Ube3cRatholoprosencephaly 3  ISOUBE3C (Homo sapiens)8554872ClinVar Annotator: match by term: Holoprosencephaly 3ClinVarPMID:10631160 more ...
Ube3cRatNEURODEVELOPMENTAL DISORDER WITH ABSENT SPEECH AND MOVEMENT AND BEHAVIORAL ABNORMALITIES  ISOUBE3C (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorder with absent speech and movement and behavioral abnormalitiesClinVarPMID:25741868 and PMID:36401616
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube3cRatjuvenile rheumatoid arthritis  ISOUBE3C (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19565504
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube3cRatNEURODEVELOPMENTAL DISORDER WITH ABSENT SPEECH AND MOVEMENT AND BEHAVIORAL ABNORMALITIES  ISOUBE3C (Homo sapiens)7240710 OMIM 

1 to 20 of 69 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube3cRat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBE3C mRNA]CTDPMID:31150632
Ube3cRat(1->4)-beta-D-glucan multiple interactionsISOUbe3c (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UBE3C mRNACTDPMID:36331819
Ube3cRat1,2-dimethylhydrazine decreases expressionISOUbe3c (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of UBE3C mRNACTDPMID:22206623
Ube3cRat17alpha-ethynylestradiol increases expressionISOUbe3c (Mus musculus)6480464Ethinyl Estradiol results in increased expression of UBE3C mRNACTDPMID:17942748
Ube3cRat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of UBE3C mRNACTDPMID:29097150
Ube3cRat17alpha-ethynylestradiol multiple interactionsISOUbe3c (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE3C mRNACTDPMID:17942748
Ube3cRat17beta-estradiol increases expressionISOUBE3C (Homo sapiens)6480464Estradiol results in increased expression of UBE3C mRNACTDPMID:31614463
Ube3cRat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOUBE3C (Homo sapiens)64804642 more ...CTDPMID:31675489
Ube3cRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOUbe3c (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE3C mRNACTDPMID:17942748
Ube3cRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of UBE3C mRNACTDPMID:33387578
Ube3cRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUbe3c (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of UBE3C mRNACTDPMID:21570461
Ube3cRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of UBE3C mRNACTDPMID:22298810
Ube3cRat2,4,6-tribromophenol decreases expressionISOUBE3C (Homo sapiens)64804642 more ...CTDPMID:31675489
Ube3cRat2-hydroxypropanoic acid decreases expressionISOUBE3C (Homo sapiens)6480464Lactic Acid results in decreased expression of UBE3C mRNACTDPMID:30851411
Ube3cRat2-methylcholine affects expressionISOUBE3C (Homo sapiens)6480464beta-methylcholine affects the expression of UBE3C mRNACTDPMID:21179406
Ube3cRat3,3',5,5'-tetrabromobisphenol A decreases expressionISOUBE3C (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of UBE3C proteinCTDPMID:31675489
Ube3cRat4,4'-sulfonyldiphenol increases expressionISOUbe3c (Mus musculus)6480464bisphenol S results in increased expression of UBE3C mRNACTDPMID:39298647
Ube3cRat4,4'-sulfonyldiphenol decreases methylationISOUBE3C (Homo sapiens)6480464bisphenol S results in decreased methylation of UBE3C geneCTDPMID:31601247
Ube3cRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of UBE3C mRNACTDPMID:30047161
Ube3cRatacetylsalicylic acid affects response to substanceISOUBE3C (Homo sapiens)6480464UBE3C polymorphism affects the susceptibility to AspirinCTDPMID:20934631

1 to 20 of 69 rows

Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube3cRatprotein K29-linked ubiquitination involved_inISOUBE3C (Homo sapiens)1624291 PMID:11278995 more ...RGDPMID:11278995 more ...
Ube3cRatprotein K29-linked ubiquitination involved_inIEAUniProtKB:Q15386 and ensembl:ENSP000003091981600115GO_REF:0000107EnsemblGO_REF:0000107
Ube3cRatprotein K29-linked ubiquitination involved_inISOUBE3C (Homo sapiens) and UniProtKB:Q15386-31624291 PMID:33637724RGDPMID:33637724
Ube3cRatprotein K48-linked ubiquitination involved_inISOUBE3C (Homo sapiens) and UniProtKB:Q15386-31624291 PMID:33637724RGDPMID:33637724
Ube3cRatprotein K48-linked ubiquitination involved_inIEAUniProtKB:Q15386 and ensembl:ENSP000003091981600115GO_REF:0000107EnsemblGO_REF:0000107
Ube3cRatprotein K48-linked ubiquitination involved_inISOUBE3C (Homo sapiens)1624291 PMID:11278995 and PMID:32039437RGDPMID:11278995 and PMID:32039437
Ube3cRatprotein polyubiquitination involved_inISOUBE3C (Homo sapiens)1624291 PMID:11278995RGDPMID:11278995
Ube3cRatprotein polyubiquitination involved_inIEAInterPro:IPR0446111600115GO_REF:0000002InterProGO_REF:0000002
Ube3cRatprotein polyubiquitination involved_inIEAUniProtKB:Q15386 and ensembl:ENSP000003091981600115GO_REF:0000107EnsemblGO_REF:0000107
Ube3cRatprotein polyubiquitination involved_inIBAPANTHER:PTN000134458 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ube3cRatubiquitin-dependent protein catabolic process involved_inISOUBE3C (Homo sapiens) and UniProtKB:Q15386-31624291 PMID:33637724RGDPMID:33637724
Ube3cRatubiquitin-dependent protein catabolic process involved_inIBAPANTHER:PTN000134458 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 12 of 12 rows

Molecular Function

  

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ube3cRatubiquitin/proteasome degradation pathway  IEA 6907045 KEGGrno:04120

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11278995   PMID:31505169  



Ube3c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr846,323,831 - 6,425,085 (-)NCBIGRCr8
mRatBN7.245,648,932 - 5,749,922 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl45,648,690 - 5,750,011 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.042,505,912 - 2,606,710 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl42,505,909 - 2,606,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.042,558,670 - 2,659,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44889,640 - 991,900 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera44,569,408 - 4,670,465 (+)NCBICelera
Cytogenetic Map4q11NCBI
UBE3C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387157,138,926 - 157,269,370 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7157,138,926 - 157,269,370 (+)EnsemblGRCh38hg38GRCh38
GRCh377156,931,620 - 157,062,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367156,624,425 - 156,754,823 (+)NCBINCBI36Build 36hg18NCBI36
Build 347156,431,139 - 156,561,538NCBI
Celera7151,358,691 - 151,489,117 (+)NCBICelera
Cytogenetic Map7q36.3NCBI
HuRef7150,661,434 - 150,792,261 (+)NCBIHuRef
CHM1_17156,940,195 - 157,070,555 (+)NCBICHM1_1
T2T-CHM13v2.07158,326,736 - 158,457,202 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27156,160,941 - 156,291,386 (+)NCBI
Ube3c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39529,774,240 - 29,881,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl529,774,240 - 29,881,090 (+)EnsemblGRCm39 Ensembl
GRCm38529,569,242 - 29,676,077 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl529,569,242 - 29,676,092 (+)EnsemblGRCm38mm10GRCm38
MGSCv37529,895,782 - 30,002,617 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36529,900,029 - 30,006,864 (+)NCBIMGSCv36mm8
Celera527,085,025 - 27,191,855 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map515.12NCBI
Ube3c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955579127,533 - 207,522 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955579127,535 - 207,522 (+)NCBIChiLan1.0ChiLan1.0
UBE3C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26193,582,714 - 193,714,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1745,592,983 - 45,724,609 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07148,756,024 - 148,886,688 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17160,474,770 - 160,580,046 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7160,474,767 - 160,580,046 (+)Ensemblpanpan1.1panPan2
UBE3C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11619,590,115 - 19,716,664 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1619,589,172 - 19,777,260 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1620,165,614 - 20,284,646 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01621,320,824 - 21,447,476 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1621,320,338 - 21,447,456 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11619,689,672 - 19,816,144 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01620,271,842 - 20,398,679 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01620,324,371 - 20,451,051 (+)NCBIUU_Cfam_GSD_1.0
Ube3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051181,724,225 - 1,817,737 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936797452,597 - 529,631 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE3C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl181,542,163 - 1,653,982 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1181,542,454 - 1,654,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2181,571,168 - 1,621,715 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBE3C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121125,262,772 - 125,397,639 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21125,262,906 - 125,397,898 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607221,496,329 - 21,632,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube3c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248001,274,825 - 1,366,553 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248001,276,697 - 1,366,547 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Ube3c
268 total Variants

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:85
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000015232
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat

1 to 10 of 20 rows
RH125662  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.042,593,724 - 2,593,981NCBIRnor5.0
RGSC_v3.44956,825 - 957,081UniSTSRGSC3.4
Cytogenetic Map4q11UniSTS
RH137703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.245,696,517 - 5,696,693 (-)MAPPERmRatBN7.2
Rnor_6.042,558,720 - 2,558,895NCBIRnor6.0
Rnor_5.042,611,529 - 2,611,704UniSTSRnor5.0
RGSC_v3.44938,093 - 938,268UniSTSRGSC3.4
Celera44,622,475 - 4,622,650UniSTS
Cytogenetic Map4q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000015232   ⟹   ENSRNOP00000015232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl45,648,690 - 5,749,690 (-)Ensembl
Rnor_6.0 Ensembl42,527,434 - 2,606,655 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092756   ⟹   ENSRNOP00000076040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl45,648,690 - 5,750,011 (-)Ensembl
Rnor_6.0 Ensembl42,505,909 - 2,590,678 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092992   ⟹   ENSRNOP00000075978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl42,593,876 - 2,606,474 (+)Ensembl
RefSeq Acc Id: NM_001427087   ⟹   NP_001414016
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr846,323,831 - 6,424,845 (-)NCBI
RefSeq Acc Id: XM_039108546   ⟹   XP_038964474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr846,324,078 - 6,403,471 (-)NCBI
mRatBN7.245,649,946 - 5,728,335 (-)NCBI
RefSeq Acc Id: XR_005503372
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr846,325,719 - 6,425,085 (-)NCBI
mRatBN7.245,648,932 - 5,749,922 (-)NCBI
Protein RefSeqs NP_001414016 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964474 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86428 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015232
  ENSRNOP00000015232.8
  ENSRNOP00000076040.2
Ensembl Acc Id: ENSRNOP00000076040   ⟸   ENSRNOT00000092756
Ensembl Acc Id: ENSRNOP00000075978   ⟸   ENSRNOT00000092992
Ensembl Acc Id: ENSRNOP00000015232   ⟸   ENSRNOT00000015232
RefSeq Acc Id: XP_038964474   ⟸   XM_039108546
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001414016   ⟸   NM_001427087
- UniProtKB: D3ZHB7 (UniProtKB/TrEMBL),   A0A1B0GWW0 (UniProtKB/TrEMBL)
HECT

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHB7-F1-model_v2 AlphaFold D3ZHB7 1-936 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692773
Promoter ID:EPDNEW_R3297
Type:multiple initiation site
Name:Ube3c_1
Description:ubiquitin protein ligase E3C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3298  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.042,505,894 - 2,505,954EPDNEW
RGD ID:13692780
Promoter ID:EPDNEW_R3298
Type:initiation region
Name:Ube3c_2
Description:ubiquitin protein ligase E3C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3297  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.042,506,140 - 2,506,200EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46171 BioCyc
Ensembl Genes ENSRNOG00000010702 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015232 ENTREZGENE
  ENSRNOT00000015232.8 UniProtKB/TrEMBL
  ENSRNOT00000092756.2 UniProtKB/TrEMBL
Gene3D-CATH Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domains UniProtKB/TrEMBL
InterPro E3B/C UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
NCBI Gene 362294 ENTREZGENE
PANTHER PTHR45700 UniProtKB/TrEMBL
  UBIQUITIN-PROTEIN LIGASE E3C UniProtKB/TrEMBL
Pfam HECT UniProtKB/TrEMBL
PhenoGen Ube3c PhenoGen
PROSITE HECT UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010702 RatGTEx
SMART HECTc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP HECT UniProtKB/TrEMBL
UniProt A0A1B0GWW0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHB7 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Ube3c  ubiquitin protein ligase E3C  RGD1559986_predicted  similar to ubiquitin protein ligase E3C (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1559986_predicted  similar to ubiquitin protein ligase E3C (predicted)  LOC362294  similar to ubiquitin protein ligase E3C  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC362294  similar to ubiquitin protein ligase E3C      Symbol and Name status set to provisional 70820 PROVISIONAL