Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Apool | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of APOOL mRNA] | CTD | PMID:31150632 | Apool | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Apool (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of APOOL mRNA | CTD | PMID:36331819 | Apool | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Apool (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of APOOL mRNA | CTD | PMID:22206623 | Apool | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of APOOL mRNA | CTD | PMID:17101203 | Apool | Rat | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of APOOL protein | CTD | PMID:33236894 | Apool | Rat | aflatoxin B1 | decreases expression | ISO | Apool (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of APOOL mRNA | CTD | PMID:19770486 | Apool | Rat | aflatoxin B1 | decreases methylation | ISO | APOOL (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of APOOL gene | CTD | PMID:27153756 | Apool | Rat | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | aristolochic acid A | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of APOOL mRNA | CTD | PMID:33212167 | Apool | Rat | arsane | affects methylation | ISO | APOOL (Homo sapiens) | 6480464 | Arsenic affects the methylation of APOOL gene | CTD | PMID:25304211 | Apool | Rat | arsenic atom | affects methylation | ISO | APOOL (Homo sapiens) | 6480464 | Arsenic affects the methylation of APOOL gene | CTD | PMID:25304211 | Apool | Rat | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | benzo[a]pyrene | decreases methylation | ISO | APOOL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of APOOL 3' UTR | CTD | PMID:27901495 | Apool | Rat | benzo[a]pyrene | affects methylation | ISO | APOOL (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of APOOL promoter | CTD | PMID:27901495 | Apool | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Apool (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of APOOL mRNA | CTD | PMID:19850644 | Apool | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Apool (Mus musculus) | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of APOOL mRNA] | CTD | PMID:19850644 | Apool | Rat | bortezomib | increases expression | ISO | APOOL (Homo sapiens) | 6480464 | Bortezomib results in increased expression of APOOL mRNA | CTD | PMID:20977926 | Apool | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of APOOL mRNA | CTD | PMID:24136188 | Apool | Rat | caffeine | decreases phosphorylation | ISO | APOOL (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of APOOL protein | CTD | PMID:35688186 | Apool | Rat | cisplatin | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of APOOL mRNA | CTD | PMID:27594783 | Apool | Rat | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | copper(II) sulfate | increases expression | ISO | APOOL (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of APOOL mRNA | CTD | PMID:19549813 | Apool | Rat | cyclosporin A | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of APOOL mRNA | CTD | PMID:25562108 | Apool | Rat | Dibutyl phosphate | affects expression | ISO | APOOL (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of APOOL mRNA | CTD | PMID:37042841 | Apool | Rat | dicrotophos | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of APOOL mRNA | CTD | PMID:28302478 | Apool | Rat | doxorubicin | decreases expression | ISO | Apool (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of APOOL mRNA | CTD | PMID:26873546 | Apool | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of APOOL mRNA | CTD | PMID:24136188 | Apool | Rat | formaldehyde | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of APOOL mRNA | CTD | PMID:23649840 | Apool | Rat | glycidyl methacrylate | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | glycidyl methacrylate results in decreased expression of APOOL protein | CTD | PMID:36641056 | Apool | Rat | inulin | multiple interactions | ISO | Apool (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of APOOL mRNA | CTD | PMID:36331819 | Apool | Rat | isotretinoin | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of APOOL mRNA | CTD | PMID:20436886 | Apool | Rat | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | methidathion | decreases expression | ISO | Apool (Mus musculus) | 6480464 | methidathion results in decreased expression of APOOL mRNA | CTD | PMID:34813904 | Apool | Rat | methylmercury chloride | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of APOOL mRNA | CTD | PMID:28001369 | Apool | Rat | methylmercury chloride | increases expression | ISO | APOOL (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of APOOL mRNA | CTD | PMID:28001369 | Apool | Rat | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of APOOL mRNA | CTD | PMID:25729387 | Apool | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of APOOL mRNA | CTD | PMID:25729387 | Apool | Rat | paracetamol | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of APOOL mRNA | CTD | PMID:21420995 | Apool | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of APOOL mRNA | CTD | PMID:33387578 | Apool | Rat | PCB138 | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | Apool | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Apool (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of APOOL mRNA more ... | CTD | PMID:36331819 | Apool | Rat | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | temozolomide | increases expression | ISO | APOOL (Homo sapiens) | 6480464 | Temozolomide results in increased expression of APOOL mRNA | CTD | PMID:31758290 | Apool | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of APOOL mRNA] | CTD | PMID:31150632 | Apool | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of APOOL mRNA | CTD | PMID:31150632 | Apool | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of APOOL mRNA | CTD | PMID:19483382 | Apool | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of APOOL mRNA | CTD | PMID:34492290 | Apool | Rat | tolcapone | decreases expression | EXP | | 6480464 | tolcapone results in decreased expression of APOOL mRNA | CTD | PMID:24136188 | Apool | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of APOOL mRNA | CTD | PMID:25729387 | Apool | Rat | triphenyl phosphate | affects expression | ISO | APOOL (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of APOOL mRNA | CTD | PMID:37042841 | Apool | Rat | triptonide | decreases expression | ISO | Apool (Mus musculus) | 6480464 | triptonide results in decreased expression of APOOL mRNA | CTD | PMID:33045310 | Apool | Rat | valproic acid | decreases expression | ISO | APOOL (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of APOOL mRNA | CTD | PMID:23179753 | Apool | Rat | valproic acid | increases methylation | ISO | APOOL (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of APOOL gene | CTD | PMID:29154799 | Apool | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of APOOL mRNA | CTD | PMID:22615374 | |