Olr765 (olfactory receptor 765) - Rat Genome Database

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Gene: Olr765 (olfactory receptor 765) Rattus norvegicus
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Symbol: Olr765 (Ensembl: Or4f4a)
Name: olfactory receptor 765 (Ensembl:olfactory receptor family 4 subfamily F member 4A)
RGD ID: 1334032
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR4F17 (olfactory receptor family 4 subfamily F member 17); INTERACTS WITH bisphenol A; 2-palmitoylglycerol (ortholog); aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: olfactory receptor 4F4; olfactory receptor 765 (predicted); olfactory receptor gene Olr765; olfactory receptor Olr765; Olr765_predicted
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83118,573,260 - 118,575,527 (+)NCBIGRCr8
mRatBN7.2398,118,744 - 98,121,011 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl398,097,957 - 98,101,421 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl398,117,901 - 98,121,398 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.03102,722,070 - 102,724,337 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3102,723,402 - 102,724,337 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03109,318,406 - 109,320,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4397,102,313 - 97,104,580 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera397,122,095 - 97,124,362 (+)NCBICelera
Cytogenetic Map3q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Olr765Rat2-palmitoylglycerol increases expressionISOOR4F17 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of OR4F17 mRNACTDPMID:37199045
Olr765Rataflatoxin B1 decreases methylationISOOR4F17 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of OR4F17 geneCTDPMID:27153756
Olr765Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of OR4F17 mRNACTDPMID:25181051
Olr765Ratniclosamide decreases expressionISOOR4F17 (Homo sapiens)6480464Niclosamide results in decreased expression of OR4F17 mRNACTDPMID:36318118


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Olr765Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Olr765Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Olr765RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Olr765RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Olr765RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Olr765Ratsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Olr765Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Olr765Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Olr765Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Olr765Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Olr765Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Olr765Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Olr765RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Olr765RatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Olr765Ratolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Olr765Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Olr765Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


Olr765
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83118,573,260 - 118,575,527 (+)NCBIGRCr8
mRatBN7.2398,118,744 - 98,121,011 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl398,097,957 - 98,101,421 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl398,117,901 - 98,121,398 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.03102,722,070 - 102,724,337 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3102,723,402 - 102,724,337 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03109,318,406 - 109,320,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4397,102,313 - 97,104,580 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera397,122,095 - 97,124,362 (+)NCBICelera
Cytogenetic Map3q34NCBI
OR4F17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819107,104 - 113,156 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19107,104 - 117,102 (+)EnsemblGRCh38hg38GRCh38
GRCh3719107,104 - 113,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361961,679 - 62,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 341961,678 - 62,596NCBI
Cytogenetic Map19p13.3NCBI
CHM1_119110,433 - 111,350 (+)NCBICHM1_1
T2T-CHM13v2.01958,109 - 64,470 (+)NCBIT2T-CHM13v2.0
Or4f17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392111,357,649 - 111,358,587 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2111,355,548 - 111,363,624 (+)EnsemblGRCm39 Ensembl
GRCm382111,527,304 - 111,528,242 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2111,525,203 - 111,533,279 (+)EnsemblGRCm38mm10GRCm38
MGSCv372111,357,822 - 111,368,399 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362111,318,504 - 111,337,309 (+)NCBIMGSCv36mm8
Celera2112,673,875 - 112,684,451 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.75NCBI

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Variants in Olr765
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:19
Count of miRNA genes:19
Interacting mature miRNAs:19
Transcripts:ENSRNOT00000040298
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat

1 to 10 of 39 rows





RefSeq Transcripts XM_006224642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000040298   ⟹   ENSRNOP00000050284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl398,097,957 - 98,101,421 (+)Ensembl
Rnor_6.0 Ensembl3102,723,402 - 102,724,337 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089603   ⟹   ENSRNOP00000075150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl398,117,901 - 98,121,398 (+)Ensembl
RefSeq Acc Id: XM_006234700   ⟹   XP_006234762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83118,573,260 - 118,575,527 (+)NCBI
mRatBN7.2398,118,744 - 98,121,011 (+)NCBI
Rnor_6.03102,722,070 - 102,724,337 (+)NCBI
Rnor_5.03109,318,406 - 109,320,673 (+)NCBI
Sequence:
Protein RefSeqs XP_006234762 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075150.2
RefSeq Acc Id: XP_006234762   ⟸   XM_006234700
- UniProtKB: A0A0G2K9V9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050284   ⟸   ENSRNOT00000040298
Ensembl Acc Id: ENSRNOP00000075150   ⟸   ENSRNOT00000089603
Name Modeler Protein Id AA Range Protein Structure
AF-F1LT92-F1-model_v2 AlphaFold F1LT92 1-311 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-48438 BioCyc
Ensembl Genes ENSRNOG00000046942 Ensembl
  ENSRNOG00000055449 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089603.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
NCBI Gene Olr765 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Olr765 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046942 RatGTEx
  ENSRNOG00000055449 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0G2K9V9 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Olr765  olfactory receptor 765   Olr765_predicted  olfactory receptor 765 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr765_predicted  olfactory receptor 765 (predicted)      Symbol and Name status set to approved 70820 APPROVED