Ufsp2 (UFM1-specific peptidase 2) - Rat Genome Database

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Gene: Ufsp2 (UFM1-specific peptidase 2) Rattus norvegicus
Analyze
Symbol: Ufsp2
Name: UFM1-specific peptidase 2
RGD ID: 1311161
Description: Predicted to enable deUFMylase activity. Predicted to be involved in several processes, including regulation of intracellular estrogen receptor signaling pathway; regulation of macromolecule metabolic process; and rescue of stalled ribosome. Predicted to be located in cytoplasm. Predicted to be active in endoplasmic reticulum and nucleus. Human ortholog(s) of this gene implicated in Beukes hip dysplasia and developmental and epileptic encephalopathy 106. Orthologous to human UFSP2 (UFM1 specific peptidase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361151; RGD1311161; similar to RIKEN cDNA 1810047C23; ufm1-specific protease 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81653,004,590 - 53,023,640 (-)NCBIGRCr8
mRatBN7.21646,272,016 - 46,291,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,272,016 - 46,291,059 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1651,673,351 - 51,692,467 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01655,042,523 - 55,061,333 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01650,312,726 - 50,331,842 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01649,465,958 - 49,484,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1649,465,968 - 49,484,985 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,192,524 - 49,211,689 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,552,474 - 49,571,471 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11649,552,551 - 49,571,546 (-)NCBI
Celera1644,270,417 - 44,289,211 (-)NCBICelera
Cytogenetic Map16q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 16 of 16 rows
Object Symbol
Species
Term
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Evidence
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Reference
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Original Reference(s)
Ufsp2Ratautistic disorder  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Ufsp2RatBeukes hip dysplasia  ISOUFSP2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:21228277 more ...
Ufsp2RatCerebral Visual Impairment and Intellectual Disability  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebral visual impairment and intellectual disabilityClinVarPMID:26350515
Ufsp2Ratdevelopmental and epileptic encephalopathy 1  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: X-Linked Infantile Spasm SyndromeClinVarPMID:25741868 more ...
Ufsp2Ratdevelopmental and epileptic encephalopathy 106  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy 106ClinVarPMID:25741868 more ...
Ufsp2Ratdevelopmental dysplasia of the hip  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental dysplasia of the hipClinVarPMID:25741868
Ufsp2Ratdilated cardiomyopathy  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary dilated cardiomyopathyClinVarPMID:28492532
Ufsp2Ratepilepsy  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: SeizuresClinVarPMID:25741868 more ...
Ufsp2Ratfocal epilepsy  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Focal-onset seizureClinVarPMID:25741868 more ...
Ufsp2Ratgeneralized epilepsy  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 more ...
Ufsp2RatHerpes Simplex Encephalitis 1  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Herpes simplex encephalitis more ...ClinVarPMID:15042513 more ...
Ufsp2Ratintellectual disability  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: intellectual disabilitiesClinVarPMID:25741868 more ...
Ufsp2Ratmicrocephaly  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: MicrocephalyClinVarPMID:25741868 more ...
Ufsp2RatNervous System Malformations  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Abnormality of the nervous systemClinVarPMID:25741868 more ...
Ufsp2Ratolivopontocerebellar atrophy  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Olivopontocerebellar hypoplasiaClinVarPMID:25741868 more ...
Ufsp2RatSPONDYLOEPIMETAPHYSEAL DYSPLASIA, DI ROCCO TYPE  ISOUFSP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Spondyloepimetaphyseal dysplasia and di rocco typeClinVarPMID:21228277 more ...
1 to 16 of 16 rows
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Original Reference(s)
Ufsp2RatBeukes hip dysplasia  ISOUFSP2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 

1 to 20 of 44 rows

  
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Original Reference(s)
Ufsp2Rat1,2-dimethylhydrazine decreases expressionISOUfsp2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of UFSP2 mRNACTDPMID:22206623
Ufsp2Rat1,2-dimethylhydrazine multiple interactionsISOUfsp2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UFSP2 mRNACTDPMID:22206623
Ufsp2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOUFSP2 (Homo sapiens)64804642 more ...CTDPMID:31675489
Ufsp2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of UFSP2 mRNACTDPMID:18796159 and PMID:33387578
Ufsp2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUfsp2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of UFSP2 mRNACTDPMID:21570461 and PMID:24680724
Ufsp2Rat2,4,6-tribromophenol decreases expressionISOUFSP2 (Homo sapiens)64804642 more ...CTDPMID:31675489
Ufsp2Rat2-hydroxypropanoic acid decreases expressionISOUFSP2 (Homo sapiens)6480464Lactic Acid results in decreased expression of UFSP2 mRNACTDPMID:30851411
Ufsp2Rat2-methylcholine affects expressionISOUFSP2 (Homo sapiens)6480464beta-methylcholine affects the expression of UFSP2 mRNACTDPMID:21179406
Ufsp2Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOUFSP2 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of UFSP2 proteinCTDPMID:31675489
Ufsp2Ratall-trans-retinoic acid decreases expressionISOUFSP2 (Homo sapiens)6480464Tretinoin results in decreased expression of UFSP2 mRNACTDPMID:33167477
Ufsp2Ratamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of UFSP2 mRNACTDPMID:30779732
Ufsp2Ratantirheumatic drug increases expressionISOUFSP2 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of UFSP2 mRNACTDPMID:24449571
Ufsp2Rataristolochic acid A decreases expressionISOUFSP2 (Homo sapiens)6480464aristolochic acid I results in decreased expression of UFSP2 mRNACTDPMID:33212167
Ufsp2Ratbenzo[a]pyrene multiple interactionsISOUfsp2 (Mus musculus)6480464AHR protein affects the reaction [Benzo(a)pyrene affects the expression of UFSP2 mRNA] and Benzo(a)pyrene promotes the reaction [AHR protein binds to UFSP2 promoter]CTDPMID:19654925 and PMID:22228805
Ufsp2Ratbenzo[a]pyrene increases methylationISOUFSP2 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of UFSP2 promoterCTDPMID:27901495
Ufsp2Ratbenzo[a]pyrene increases expressionISOUfsp2 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of UFSP2 mRNACTDPMID:22228805
Ufsp2Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of UFSP2 mRNACTDPMID:25181051
Ufsp2Ratbisphenol A decreases expressionISOUfsp2 (Mus musculus)6480464bisphenol A results in decreased expression of UFSP2 mRNACTDPMID:33221593
Ufsp2Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of UFSP2 mRNACTDPMID:30816183 more ...
Ufsp2Ratbisphenol AF increases expressionISOUFSP2 (Homo sapiens)6480464bisphenol AF results in increased expression of UFSP2 proteinCTDPMID:34186270

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Biological Process
1 to 17 of 17 rows

  
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Original Reference(s)
Ufsp2Ratnegative regulation of proteolysis involved in protein catabolic process involved_inISOUFSP2 (Homo sapiens)1624291 PMID:36543799RGDPMID:36543799
Ufsp2Ratnegative regulation of proteolysis involved in protein catabolic process involved_inIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratproteolysis involved_inISSUniProtKB:Q9NUQ71600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2Ratproteolysis involved_inIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratproteolysis involved_inIBAPANTHER:PTN008489070 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ufsp2Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2Ratproteolysis involved_inISOUFSP2 (Homo sapiens)1624291 PMID:25219498RGDPMID:25219498
Ufsp2Ratregulation of intracellular estrogen receptor signaling pathway involved_inISSUniProtKB:Q9NUQ71600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2Ratregulation of intracellular estrogen receptor signaling pathway involved_inIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratregulation of intracellular estrogen receptor signaling pathway involved_inISOUFSP2 (Homo sapiens)1624291 PMID:25219498RGDPMID:25219498
Ufsp2Ratregulation of type II interferon production involved_inISOUfsp2 (Mus musculus)1624291 PMID:33372156RGDPMID:33372156
Ufsp2Ratregulation of type II interferon production involved_inIEAUniProtKB:Q99K23 and ensembl:ENSMUSP000000340511600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratrescue of stalled ribosome involved_inISOUFSP2 (Homo sapiens)1624291 PMID:38383785RGDPMID:38383785
Ufsp2Ratrescue of stalled ribosome involved_inIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratribosome disassembly involved_inISOUFSP2 (Homo sapiens)1624291 PMID:38383785RGDPMID:38383785
Ufsp2Ratribosome disassembly involved_inIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratribosome disassembly involved_inISSUniProtKB:Q9NUQ71600115GO_REF:0000024UniProtGO_REF:0000024
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Cellular Component
1 to 19 of 19 rows

  
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Original Reference(s)
Ufsp2Ratcytoplasm located_inISOUfsp2 (Mus musculus)1624291 PMID:21228277RGDPMID:21228277
Ufsp2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Ufsp2Ratcytoplasm located_inIEAUniProtKB:Q99K23 and ensembl:ENSMUSP000000340511600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratcytoplasm located_inISSUniProtKB:Q99K231600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2Ratendoplasmic reticulum is_active_inISOUFSP2 (Homo sapiens)1624291 PMID:35926457RGDPMID:35926457
Ufsp2Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Ufsp2Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2Ratendoplasmic reticulum is_active_inIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratendoplasmic reticulum located_inISOUfsp2 (Mus musculus)1624291 PMID:21228277RGDPMID:21228277
Ufsp2Ratendoplasmic reticulum located_inIEAUniProtKB:Q99K23 and ensembl:ENSMUSP000000340511600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratendoplasmic reticulum located_inISSUniProtKB:Q99K231600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2Ratendoplasmic reticulum is_active_inIBAMGI:1913679 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ufsp2Ratnucleus located_inISSUniProtKB:Q99K231600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2Ratnucleus located_inIEAUniProtKB:Q99K23 and ensembl:ENSMUSP000000340511600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Ufsp2Ratnucleus located_inISOUfsp2 (Mus musculus)1624291 PMID:21228277RGDPMID:21228277
Ufsp2Ratnucleus is_active_inIBAMGI:1913679 and PANTHER:PTN0084890701600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function
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Original Reference(s)
Ufsp2Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2RatdeUFMylase activity enablesISOUFSP2 (Homo sapiens)1624291 PMID:25219498 more ...RGDPMID:25219498 more ...
Ufsp2RatdeUFMylase activity enablesIEAUniProtKB:Q9NUQ7 and ensembl:ENSP000002646891600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2RatdeUFMylase activity enablesISOUfsp2 (Mus musculus)1624291 PMID:17182609 more ...RGDPMID:17182609 more ...
Ufsp2RatdeUFMylase activity enablesISSUniProtKB:Q9NUQ71600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2RatdeUFMylase activity enablesIEAARBA:ARBA000450551600115GO_REF:0000117UniProtGO_REF:0000117
Ufsp2RatdeUFMylase activity enablesIBAMGI:1913679 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ufsp2RatdeUFMylase activity enablesIEAUniProtKB:Q99K23 and ensembl:ENSMUSP000000340511600115GO_REF:0000107EnsemblGO_REF:0000107
Ufsp2RatdeUFMylase activity enablesISSUniProtKB:Q99K231600115GO_REF:0000024UniProtGO_REF:0000024
Ufsp2Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Ufsp2Ratprotein binding enablesISOUFSP2 (Homo sapiens)1624291UniProtKB:P25800 more ...RGDPMID:25219498 and PMID:32296183
1 to 12 of 12 rows


#
Reference Title
Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:15489334   PMID:17182609   PMID:21228277   PMID:25219498  



Ufsp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81653,004,590 - 53,023,640 (-)NCBIGRCr8
mRatBN7.21646,272,016 - 46,291,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,272,016 - 46,291,059 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1651,673,351 - 51,692,467 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01655,042,523 - 55,061,333 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01650,312,726 - 50,331,842 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01649,465,958 - 49,484,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1649,465,968 - 49,484,985 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,192,524 - 49,211,689 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,552,474 - 49,571,471 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11649,552,551 - 49,571,546 (-)NCBI
Celera1644,270,417 - 44,289,211 (-)NCBICelera
Cytogenetic Map16q11NCBI
UFSP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384185,399,537 - 185,425,964 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4185,399,537 - 185,425,979 (-)EnsemblGRCh38hg38GRCh38
GRCh374186,320,691 - 186,347,118 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364186,558,437 - 186,584,062 (-)NCBINCBI36Build 36hg18NCBI36
Celera4183,646,881 - 183,673,344 (-)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4182,074,147 - 182,100,608 (-)NCBIHuRef
CHM1_14186,297,123 - 186,323,567 (-)NCBICHM1_1
T2T-CHM13v2.04188,742,869 - 188,769,306 (-)NCBIT2T-CHM13v2.0
Ufsp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39846,428,551 - 46,449,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl846,428,565 - 46,449,995 (+)EnsemblGRCm39 Ensembl
GRCm38845,975,515 - 45,996,958 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl845,975,528 - 45,996,958 (+)EnsemblGRCm38mm10GRCm38
MGSCv37847,060,893 - 47,082,214 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36847,474,350 - 47,495,677 (+)NCBIMGSCv36mm8
Celera848,658,421 - 48,679,785 (+)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map825.96NCBI
Ufsp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540323,634,924 - 23,655,429 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540323,634,967 - 23,655,429 (+)NCBIChiLan1.0ChiLan1.0
UFSP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23183,135,368 - 183,161,258 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14183,483,721 - 183,509,626 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04177,562,642 - 177,589,312 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,779,242 - 189,805,572 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4189,779,242 - 189,805,572 (-)Ensemblpanpan1.1panPan2
UFSP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,208,741 - 45,230,041 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,208,863 - 45,229,996 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1645,696,365 - 45,717,679 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01647,424,777 - 47,446,091 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1647,424,825 - 47,446,091 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11645,392,610 - 45,413,913 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01646,005,444 - 46,026,743 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,136,811 - 46,158,137 (+)NCBIUU_Cfam_GSD_1.0
Ufsp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,164,685 - 34,184,002 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,925,982 - 3,948,450 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,926,046 - 3,945,575 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UFSP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1546,448,904 - 46,470,572 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11546,448,918 - 46,470,616 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21553,234,748 - 53,252,218 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UFSP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17131,352,140 - 131,375,558 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7131,350,251 - 131,375,549 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037111,613,032 - 111,637,249 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ufsp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476916,254,446 - 16,281,025 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476916,254,446 - 16,281,099 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ufsp2
121 total Variants

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:62
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000016723
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
631833Sach2Saccharin preference QTL 240.01consumption behavior trait (VT:0002069)calculated saccharin drink intake rate (CMO:0001613)164302484250166018Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat

1 to 10 of 20 rows
RH137983  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21646,272,101 - 46,273,449 (+)MAPPERmRatBN7.2
Rnor_6.01649,466,044 - 49,467,391NCBIRnor6.0
Rnor_5.01649,192,610 - 49,193,957UniSTSRnor5.0
RGSC_v3.41649,552,555 - 49,553,902UniSTSRGSC3.4
Celera1644,270,498 - 44,271,845UniSTS
RH 3.4 Map16457.2UniSTS
Cytogenetic Map16q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000016723   ⟹   ENSRNOP00000016723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1646,272,023 - 46,291,059 (-)Ensembl
Rnor_6.0 Ensembl1649,465,968 - 49,484,985 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113258   ⟹   ENSRNOP00000096031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1646,272,016 - 46,287,454 (-)Ensembl
RefSeq Acc Id: NM_001014142   ⟹   NP_001014164
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81653,004,595 - 53,023,592 (-)NCBI
mRatBN7.21646,272,021 - 46,291,022 (-)NCBI
Rnor_6.01649,465,963 - 49,484,960 (-)NCBI
Rnor_5.01649,192,524 - 49,211,689 (-)NCBI
RGSC_v3.41649,552,474 - 49,571,471 (-)RGD
Celera1644,270,417 - 44,289,211 (-)RGD
Sequence:
RefSeq Acc Id: XM_006253159   ⟹   XP_006253221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81653,004,590 - 53,019,327 (-)NCBI
mRatBN7.21646,272,016 - 46,291,037 (-)NCBI
Rnor_6.01649,465,958 - 49,484,975 (-)NCBI
Rnor_5.01649,192,524 - 49,211,689 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771265   ⟹   XP_008769487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81653,004,590 - 53,023,567 (-)NCBI
mRatBN7.21646,272,016 - 46,290,920 (-)NCBI
Rnor_6.01649,465,958 - 49,484,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094640   ⟹   XP_038950568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81653,004,590 - 53,023,640 (-)NCBI
mRatBN7.21646,272,016 - 46,291,080 (-)NCBI
RefSeq Acc Id: XM_063275518   ⟹   XP_063131588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81653,004,590 - 53,023,503 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001014164 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253221 (Get FASTA)   NCBI Sequence Viewer  
  XP_008769487 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950568 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131588 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83771 (Get FASTA)   NCBI Sequence Viewer  
  EDL78868 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016723
  ENSRNOP00000016723.4
GenBank Protein Q5XIB4 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_001014164   ⟸   NM_001014142
- UniProtKB: Q5XIB4 (UniProtKB/Swiss-Prot),   A6JPQ2 (UniProtKB/TrEMBL),   A0A8I6AQ70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253221   ⟸   XM_006253159
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQ70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769487   ⟸   XM_008771265
- Peptide Label: isoform X1
- UniProtKB: Q5XIB4 (UniProtKB/Swiss-Prot),   A6JPQ2 (UniProtKB/TrEMBL),   A0A8I6AQ70 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016723   ⟸   ENSRNOT00000016723
RefSeq Acc Id: XP_038950568   ⟸   XM_039094640
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AQ70 (UniProtKB/TrEMBL)
Ubiquitin-fold modifier 1 specific protease 2-like   UfSP1/2/DUB catalytic

Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIB4-F1-model_v2 AlphaFold Q5XIB4 1-461 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700104
Promoter ID:EPDNEW_R10627
Type:initiation region
Name:Ufsp2_1
Description:UFM1-specific peptidase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01649,484,982 - 49,485,042EPDNEW


1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-11331 BioCyc
Ensembl Genes ENSRNOG00000012087 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016723 ENTREZGENE
  ENSRNOT00000016723.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.70.130 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7193395 IMAGE-MGC_LOAD
InterPro Peptidase_C78_UfSP1/2 UniProtKB/Swiss-Prot
  UfSP2-like_N UniProtKB/Swiss-Prot
KEGG Report rno:361151 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94722 IMAGE-MGC_LOAD
NCBI Gene 361151 ENTREZGENE
PANTHER UFM1-SPECIFIC PROTEASE 2 UniProtKB/Swiss-Prot
  UFM1-SPECIFIC PROTEASE 2 UniProtKB/Swiss-Prot
Pfam Peptidase_C78 UniProtKB/Swiss-Prot
  UfSP2_N UniProtKB/Swiss-Prot
PhenoGen Ufsp2 PhenoGen
RatGTEx ENSRNOG00000012087 RatGTEx
UniProt A0A8I6AQ70 ENTREZGENE, UniProtKB/TrEMBL
  A6JPQ2 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIB4 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-31 Ufsp2  UFM1-specific peptidase 2  RGD1311161  similar to RIKEN cDNA 1810047C23  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311161  similar to RIKEN cDNA 1810047C23  RGD1311161_predicted  similar to RIKEN cDNA 1810047C23 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311161_predicted  similar to RIKEN cDNA 1810047C23 (predicted)  LOC361151_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361151_predicted  similar to RIKEN cDNA 1810047C23 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL