Ptgr2 (prostaglandin reductase 2) - Rat Genome Database

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Gene: Ptgr2 (prostaglandin reductase 2) Rattus norvegicus
Analyze
Symbol: Ptgr2
Name: prostaglandin reductase 2
RGD ID: 1310518
Description: Predicted to enable 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be located in cytoplasm. Orthologous to human PTGR2 (prostaglandin reductase 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 15-oxoprostaglandin 13-reductase; LOC299194; MGC108784; PRG-2; Zadh1; zinc binding alcohol dehydrogenase, domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,662,469 - 109,694,232 (+)NCBIGRCr8
mRatBN7.26103,931,367 - 103,963,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,931,409 - 103,963,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,093,166 - 104,124,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,392,251 - 104,423,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,761,828 - 103,793,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,999,832 - 108,031,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,514,752 - 117,546,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,349,172 - 108,380,867 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,352,627 - 108,384,321 (+)NCBI
Celera6101,759,837 - 101,791,510 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptgr2Ratintellectual disability  ISOPTGR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and mildClinVar 
Ptgr2Ratprimary ciliary dyskinesia 16  ISOPTGR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary ciliary dyskinesia 16ClinVarPMID:21496787 and PMID:28492532

1 to 20 of 92 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptgr2Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PTGR2 mRNA]CTDPMID:31150632
Ptgr2Rat1,1-dichloroethene decreases expressionISOPtgr2 (Mus musculus)6480464vinylidene chloride results in decreased expression of PTGR2 mRNACTDPMID:26682919
Ptgr2Rat1,2-dimethylhydrazine decreases expressionISOPtgr2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PTGR2 mRNACTDPMID:22206623
Ptgr2Rat17alpha-ethynylestradiol multiple interactionsISOPtgr2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTGR2 mRNACTDPMID:17942748
Ptgr2Rat17beta-estradiol decreases expressionISOPtgr2 (Mus musculus)6480464Estradiol results in decreased expression of PTGR2 mRNACTDPMID:39298647
Ptgr2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPtgr2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PTGR2 mRNACTDPMID:15328365
Ptgr2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPtgr2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTGR2 mRNACTDPMID:17942748
Ptgr2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PTGR2 mRNACTDPMID:22808131
Ptgr2Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of PTGR2 mRNACTDPMID:21346803
Ptgr2Rat4-hydroxyphenyl retinamide decreases expressionISOPtgr2 (Mus musculus)6480464Fenretinide results in decreased expression of PTGR2 mRNACTDPMID:28973697
Ptgr2Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PTGR2 mRNACTDPMID:30047161
Ptgr2Ratacrylamide increases expressionISOPTGR2 (Homo sapiens)6480464Acrylamide results in increased expression of PTGR2 mRNACTDPMID:32763439
Ptgr2Rataflatoxin B1 increases methylationISOPTGR2 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PTGR2 intronCTDPMID:30157460
Ptgr2Rataflatoxin B1 increases expressionISOPTGR2 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of PTGR2 mRNACTDPMID:21632981
Ptgr2RatAflatoxin B2 alpha decreases methylationISOPTGR2 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of PTGR2 intronCTDPMID:30157460
Ptgr2Ratall-trans-retinoic acid decreases expressionISOPTGR2 (Homo sapiens)6480464Tretinoin results in decreased expression of PTGR2 mRNACTDPMID:33167477
Ptgr2Ratamitrole increases expressionEXP 6480464Amitrole results in increased expression of PTGR2 mRNACTDPMID:30047161
Ptgr2Ratarsane multiple interactionsISOPTGR2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PTGR2 mRNACTDPMID:39836092
Ptgr2Ratarsenic atom multiple interactionsISOPTGR2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PTGR2 mRNACTDPMID:39836092
Ptgr2Ratbenzo[a]pyrene increases expressionISOPTGR2 (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of PTGR2 mRNACTDPMID:20106945 and PMID:21632981

1 to 20 of 92 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptgr2Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Ptgr2Ratprostaglandin metabolic process involved_inISSUniProtKB:Q8N8N71600115GO_REF:0000024UniProtGO_REF:0000024
Ptgr2Ratprostaglandin metabolic process involved_inIBAPANTHER:PTN001707453 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ptgr2Ratprostaglandin metabolic process involved_inIEAInterPro:IPR0373991600115GO_REF:0000002InterProGO_REF:0000002
Ptgr2Ratprostaglandin metabolic process involved_inISOPTGR2 (Homo sapiens)1624291 PMID:19000823RGDPMID:19000823

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptgr2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Ptgr2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 11 of 11 rows

  
1 to 11 of 11 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:18614015   PMID:19000823   PMID:23376485  



Ptgr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,662,469 - 109,694,232 (+)NCBIGRCr8
mRatBN7.26103,931,367 - 103,963,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,931,409 - 103,963,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,093,166 - 104,124,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,392,251 - 104,423,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,761,828 - 103,793,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,999,832 - 108,031,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,514,752 - 117,546,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,349,172 - 108,380,867 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,352,627 - 108,384,321 (+)NCBI
Celera6101,759,837 - 101,791,510 (+)NCBICelera
Cytogenetic Map6q31NCBI
PTGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,851,831 - 73,885,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,851,831 - 73,885,726 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,318,534 - 74,352,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,388,424 - 73,421,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 341473,388,426 - 73,421,915NCBI
Celera1454,355,472 - 54,389,115 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,485,578 - 54,519,224 (+)NCBIHuRef
CHM1_11474,258,185 - 74,291,756 (+)NCBICHM1_1
T2T-CHM13v2.01468,059,477 - 68,093,373 (+)NCBIT2T-CHM13v2.0
Ptgr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,332,011 - 84,362,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,332,006 - 84,362,606 (+)EnsemblGRCm39 Ensembl
GRCm381284,285,237 - 84,315,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,285,232 - 84,315,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,626,264 - 85,656,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361285,175,062 - 85,205,580 (+)NCBIMGSCv36mm8
Celera1285,740,324 - 85,770,857 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.14NCBI
Ptgr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,515,017 - 1,549,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,519,767 - 1,549,998 (-)NCBIChiLan1.0ChiLan1.0
PTGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,941,609 - 74,981,970 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11474,158,124 - 74,191,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,410,939 - 54,444,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,266,484 - 73,299,378 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,266,502 - 73,299,378 (+)Ensemblpanpan1.1panPan2
PTGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,095,405 - 47,120,371 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,768,242 - 46,805,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,313,084 - 47,350,058 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl847,312,781 - 47,350,047 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,980,670 - 47,017,709 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,998,391 - 47,035,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,389,163 - 47,426,127 (+)NCBIUU_Cfam_GSD_1.0
Ptgr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,903,412 - 28,945,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,123,304 - 3,166,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,123,405 - 3,165,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,174,219 - 97,195,595 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,174,143 - 97,195,601 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,928,733 - 102,950,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,060,503 - 51,095,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2451,060,608 - 51,095,303 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605339,274,452 - 39,312,455 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptgr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473427,687,195 - 27,717,548 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473427,686,993 - 27,716,802 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Ptgr2
119 total Variants

Predicted Target Of
Summary Value
Count of predictions:703
Count of miRNA genes:265
Interacting mature miRNAs:322
Transcripts:ENSRNOT00000058095, ENSRNOT00000059073
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 34 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat

1 to 10 of 34 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000058095   ⟹   ENSRNOP00000054903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,931,423 - 103,963,111 (+)Ensembl
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000059073   ⟹   ENSRNOP00000055851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,931,409 - 103,958,273 (+)Ensembl
Rnor_6.0 Ensembl6108,009,251 - 108,029,859 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118264   ⟹   ENSRNOP00000080851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,931,409 - 103,963,079 (+)Ensembl
RefSeq Acc Id: NM_001015009   ⟹   NP_001015009
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
Rnor_6.06107,999,846 - 108,031,645 (+)NCBI
Rnor_5.06117,514,752 - 117,546,565 (-)NCBI
RGSC_v3.46108,349,172 - 108,380,867 (+)RGD
Celera6101,759,837 - 101,791,510 (+)RGD
Sequence:
RefSeq Acc Id: NM_001399426   ⟹   NP_001386355
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: NM_001399433   ⟹   NP_001386362
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: NR_174185
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: NR_174186
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,498 - 109,694,232 (+)NCBI
mRatBN7.26103,931,379 - 103,963,113 (+)NCBI
RefSeq Acc Id: XM_006240327   ⟹   XP_006240389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,469 - 109,694,156 (+)NCBI
mRatBN7.26103,931,367 - 103,963,113 (+)NCBI
Rnor_6.06107,999,835 - 108,031,645 (+)NCBI
Rnor_5.06117,514,752 - 117,546,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240329   ⟹   XP_006240391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,674,256 - 109,694,156 (+)NCBI
mRatBN7.26103,943,200 - 103,963,113 (+)NCBI
Rnor_6.06108,011,662 - 108,031,645 (+)NCBI
Rnor_5.06117,514,752 - 117,546,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112026   ⟹   XP_038967954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,496 - 109,684,476 (+)NCBI
mRatBN7.26103,931,402 - 103,953,433 (+)NCBI
RefSeq Acc Id: XM_063261733   ⟹   XP_063117803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,497 - 109,694,156 (+)NCBI
RefSeq Acc Id: XM_063261734   ⟹   XP_063117804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,497 - 109,694,156 (+)NCBI
RefSeq Acc Id: XM_063261735   ⟹   XP_063117805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,662,469 - 109,694,156 (+)NCBI
1 to 5 of 12 rows
1 to 5 of 12 rows
RefSeq Acc Id: NP_001015009   ⟸   NM_001015009
- Peptide Label: isoform 2
- UniProtKB: Q5BK81 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240389   ⟸   XM_006240327
- Peptide Label: isoform X1
- UniProtKB: Q5BK81 (UniProtKB/Swiss-Prot),   A6JDT8 (UniProtKB/TrEMBL),   A0A8L2QSN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240391   ⟸   XM_006240329
- Peptide Label: isoform X2
- UniProtKB: A6JDU5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054903   ⟸   ENSRNOT00000058095
Ensembl Acc Id: ENSRNOP00000055851   ⟸   ENSRNOT00000059073
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK81-F1-model_v2 AlphaFold Q5BK81 1-351 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694722
Promoter ID:EPDNEW_R5246
Type:initiation region
Name:Ptgr2_1
Description:prostaglandin reductase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06107,999,837 - 107,999,897EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-36828 BioCyc
Ensembl Genes ENSRNOG00000038166 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000058095 ENTREZGENE
  ENSRNOT00000058095.4 UniProtKB/Swiss-Prot
  ENSRNOT00000059073 ENTREZGENE
  ENSRNOT00000118264 ENTREZGENE
  ENSRNOT00000122406 ENTREZGENE
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/Swiss-Prot
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7189599 IMAGE-MGC_LOAD
InterPro ADH_C UniProtKB/Swiss-Prot
  ADH_N_2 UniProtKB/Swiss-Prot
  GroES-like_sf UniProtKB/Swiss-Prot
  MDR_fam UniProtKB/Swiss-Prot
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  PTGR2 UniProtKB/Swiss-Prot
KEGG Report rno:299194 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108784 IMAGE-MGC_LOAD
NCBI Gene 299194 ENTREZGENE
PANTHER PROSTAGLANDIN REDUCTASE 2 UniProtKB/Swiss-Prot
  PTHR43205 UniProtKB/Swiss-Prot
Pfam ADH_N_2 UniProtKB/Swiss-Prot
  ADH_zinc_N UniProtKB/Swiss-Prot
PhenoGen Ptgr2 PhenoGen
RatGTEx ENSRNOG00000038166 RatGTEx
Superfamily-SCOP SSF50129 UniProtKB/Swiss-Prot
  SSF51735 UniProtKB/Swiss-Prot
UniProt A0A8I6G545 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QSN3 ENTREZGENE, UniProtKB/TrEMBL
  A6JDT8 ENTREZGENE, UniProtKB/TrEMBL
  A6JDU4 ENTREZGENE, UniProtKB/TrEMBL
  A6JDU5 ENTREZGENE, UniProtKB/TrEMBL
  PTGR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Ptgr2  prostaglandin reductase 2  Zadh1  zinc binding alcohol dehydrogenase, domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Zadh1  zinc binding alcohol dehydrogenase, domain containing 1  Zadh1_predicted  zinc binding alcohol dehydrogenase, domain containing 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Zadh1_predicted  zinc binding alcohol dehydrogenase, domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED