PTGR2 (prostaglandin reductase 2) - Rat Genome Database

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Gene: PTGR2 (prostaglandin reductase 2) Sus scrofa
Analyze
Symbol: PTGR2
Name: prostaglandin reductase 2
RGD ID: 14235373
Description: ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN lipid metabolic process (inferred); prostaglandin metabolic process (inferred); ASSOCIATED WITH intellectual disability (ortholog); primary ciliary dyskinesia 16 (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Zinc binding alcohol dehydrogenase, domain containing 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,174,219 - 97,195,595 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,174,143 - 97,195,601 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,928,733 - 102,950,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PTGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,174,219 - 97,195,595 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,174,143 - 97,195,601 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,928,733 - 102,950,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,851,831 - 73,885,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,851,831 - 73,885,726 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,318,534 - 74,352,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,388,424 - 73,421,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 341473,388,426 - 73,421,915NCBI
Celera1454,355,472 - 54,389,115 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,485,578 - 54,519,224 (+)NCBIHuRef
CHM1_11474,258,185 - 74,291,756 (+)NCBICHM1_1
T2T-CHM13v2.01468,059,477 - 68,093,373 (+)NCBIT2T-CHM13v2.0
Ptgr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,332,011 - 84,362,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,332,006 - 84,362,606 (+)EnsemblGRCm39 Ensembl
GRCm381284,285,237 - 84,315,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,285,232 - 84,315,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,626,264 - 85,656,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361285,175,062 - 85,205,580 (+)NCBIMGSCv36mm8
Celera1285,740,324 - 85,770,857 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.14NCBI
Ptgr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,662,469 - 109,694,232 (+)NCBIGRCr8
mRatBN7.26103,931,367 - 103,963,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,931,409 - 103,963,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,093,166 - 104,124,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,392,251 - 104,423,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,761,828 - 103,793,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,999,832 - 108,031,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,514,752 - 117,546,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,349,172 - 108,380,867 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,352,627 - 108,384,321 (+)NCBI
Celera6101,759,837 - 101,791,510 (+)NCBICelera
Cytogenetic Map6q31NCBI
Ptgr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,515,017 - 1,549,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,519,767 - 1,549,998 (-)NCBIChiLan1.0ChiLan1.0
PTGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,941,609 - 74,981,970 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11474,158,124 - 74,191,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,410,939 - 54,444,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,266,484 - 73,299,378 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,266,502 - 73,299,378 (+)Ensemblpanpan1.1panPan2
PTGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,095,405 - 47,120,371 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,768,242 - 46,805,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,313,084 - 47,350,058 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl847,312,781 - 47,350,047 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,980,670 - 47,017,709 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,998,391 - 47,035,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,389,163 - 47,426,127 (+)NCBIUU_Cfam_GSD_1.0
Ptgr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,903,412 - 28,945,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,123,304 - 3,166,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,123,405 - 3,165,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,060,503 - 51,095,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2451,060,608 - 51,095,303 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605339,274,452 - 39,312,455 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptgr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473427,687,195 - 27,717,548 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473427,686,993 - 27,716,802 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PTGR2
772 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 1 5 14 12 23 3 6 2

Sequence


Ensembl Acc Id: ENSSSCT00000002615   ⟹   ENSSSCP00000002550
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl797,174,219 - 97,195,583 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000056698   ⟹   ENSSSCP00000042542
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl797,174,670 - 97,195,595 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000057994   ⟹   ENSSSCP00000043651
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl797,186,478 - 97,195,583 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000097702   ⟹   ENSSSCP00000079695
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl797,174,670 - 97,193,092 (+)Ensembl
RefSeq Acc Id: XM_001929074   ⟹   XP_001929109
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1797,174,182 - 97,195,601 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003128657   ⟹   XP_003128705
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1797,174,143 - 97,195,593 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005656387   ⟹   XP_005656444
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1797,174,184 - 97,195,313 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021099498   ⟹   XP_020955157
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1797,174,143 - 97,195,552 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003128705   ⟸   XM_003128657
- Peptide Label: isoform X1
- UniProtKB: A0A480YV73 (UniProtKB/TrEMBL),   A0A4X1TM83 (UniProtKB/TrEMBL),   A0A8D0QAL7 (UniProtKB/TrEMBL),   A0A8D1HLW3 (UniProtKB/TrEMBL),   A0A8D0LY49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020955157   ⟸   XM_021099498
- Peptide Label: isoform X2
- UniProtKB: F1S3H7 (UniProtKB/TrEMBL),   A0A8D0Y3Q1 (UniProtKB/TrEMBL),   A0A8D1KX92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_001929109   ⟸   XM_001929074
- Peptide Label: isoform X1
- UniProtKB: A0A480YV73 (UniProtKB/TrEMBL),   A0A4X1TM83 (UniProtKB/TrEMBL),   A0A8D0QAL7 (UniProtKB/TrEMBL),   A0A8D1HLW3 (UniProtKB/TrEMBL),   A0A8D0LY49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005656444   ⟸   XM_005656387
- Peptide Label: isoform X2
- UniProtKB: F1S3H7 (UniProtKB/TrEMBL),   A0A8D0Y3Q1 (UniProtKB/TrEMBL),   A0A8D1KX92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000002550   ⟸   ENSSSCT00000002615
Ensembl Acc Id: ENSSSCP00000043651   ⟸   ENSSSCT00000057994
Ensembl Acc Id: ENSSSCP00000079695   ⟸   ENSSSCT00000097702
Ensembl Acc Id: ENSSSCP00000042542   ⟸   ENSSSCT00000056698
Protein Domains
Alcohol dehydrogenase-like C-terminal   Oxidoreductase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002351 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015079814 UniProtKB/TrEMBL
  ENSSSCG00025014240 UniProtKB/TrEMBL
  ENSSSCG00030071192 UniProtKB/TrEMBL
  ENSSSCG00035061052 UniProtKB/TrEMBL
  ENSSSCG00040021295 UniProtKB/TrEMBL
  ENSSSCG00045016936 UniProtKB/TrEMBL
  ENSSSCG00050072263 UniProtKB/TrEMBL
  ENSSSCG00055022650 UniProtKB/TrEMBL
  ENSSSCG00060026591 UniProtKB/TrEMBL
  ENSSSCG00065061593 UniProtKB/TrEMBL
  ENSSSCG00070010083 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000002615 ENTREZGENE
  ENSSSCT00000002615.5 UniProtKB/TrEMBL
  ENSSSCT00000056698 ENTREZGENE
  ENSSSCT00000056698.3 UniProtKB/TrEMBL
  ENSSSCT00000057994.3 UniProtKB/TrEMBL
  ENSSSCT00000097702 ENTREZGENE
  ENSSSCT00000097702.1 UniProtKB/TrEMBL
  ENSSSCT00015108391.1 UniProtKB/TrEMBL
  ENSSSCT00015108414.1 UniProtKB/TrEMBL
  ENSSSCT00025018947.1 UniProtKB/TrEMBL
  ENSSSCT00025019025.1 UniProtKB/TrEMBL
  ENSSSCT00030099611.1 UniProtKB/TrEMBL
  ENSSSCT00030099646.1 UniProtKB/TrEMBL
  ENSSSCT00035081997.1 UniProtKB/TrEMBL
  ENSSSCT00035082003.1 UniProtKB/TrEMBL
  ENSSSCT00040028691.1 UniProtKB/TrEMBL
  ENSSSCT00045028789.1 UniProtKB/TrEMBL
  ENSSSCT00045028854.1 UniProtKB/TrEMBL
  ENSSSCT00050098638.1 UniProtKB/TrEMBL
  ENSSSCT00050098644.1 UniProtKB/TrEMBL
  ENSSSCT00055044494.1 UniProtKB/TrEMBL
  ENSSSCT00055044593.1 UniProtKB/TrEMBL
  ENSSSCT00055044685.1 UniProtKB/TrEMBL
  ENSSSCT00055044813.1 UniProtKB/TrEMBL
  ENSSSCT00060035995.1 UniProtKB/TrEMBL
  ENSSSCT00060036002.1 UniProtKB/TrEMBL
  ENSSSCT00065084407.1 UniProtKB/TrEMBL
  ENSSSCT00065084409.1 UniProtKB/TrEMBL
  ENSSSCT00065084412.1 UniProtKB/TrEMBL
  ENSSSCT00065084422.1 UniProtKB/TrEMBL
  ENSSSCT00070019613.1 UniProtKB/TrEMBL
  ENSSSCT00070019618.1 UniProtKB/TrEMBL
  ENSSSCT00070019622.1 UniProtKB/TrEMBL
  ENSSSCT00070019627.1 UniProtKB/TrEMBL
  ENSSSCT00070019645.1 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro ADH_C UniProtKB/TrEMBL
  ADH_N_2 UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/TrEMBL
  MDR_fam UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  PTGR2 UniProtKB/TrEMBL
KEGG Report ssc:100156930 UniProtKB/TrEMBL
NCBI Gene PTGR2 ENTREZGENE
PANTHER PROSTAGLANDIN REDUCTASE 2 UniProtKB/TrEMBL
  PTHR43205 UniProtKB/TrEMBL
Pfam ADH_N_2 UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A287AI29_PIG UniProtKB/TrEMBL
  A0A480YV73 ENTREZGENE
  A0A4X1TM83 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TMA9_PIG UniProtKB/TrEMBL
  A0A4X1TMG5_PIG UniProtKB/TrEMBL
  A0A8D0LY49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QAL7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Y3Q1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HLW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KX92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FN05_PIG UniProtKB/TrEMBL
  F1S3H7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480YV73 UniProtKB/TrEMBL