Ptgr2 (prostaglandin reductase 2) - Rat Genome Database

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Gene: Ptgr2 (prostaglandin reductase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Ptgr2
Name: prostaglandin reductase 2
RGD ID: 12685037
Description: ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN lipid metabolic process (inferred); prostaglandin metabolic process (inferred); ASSOCIATED WITH intellectual disability (ortholog); primary ciliary dyskinesia 16 (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,903,412 - 28,945,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,123,304 - 3,166,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,123,405 - 3,165,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ptgr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,903,412 - 28,945,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,123,304 - 3,166,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,123,405 - 3,165,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,851,831 - 73,885,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,851,831 - 73,885,726 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,318,534 - 74,352,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,388,424 - 73,421,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 341473,388,426 - 73,421,915NCBI
Celera1454,355,472 - 54,389,115 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,485,578 - 54,519,224 (+)NCBIHuRef
CHM1_11474,258,185 - 74,291,756 (+)NCBICHM1_1
T2T-CHM13v2.01468,059,477 - 68,093,373 (+)NCBIT2T-CHM13v2.0
Ptgr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,332,011 - 84,362,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,332,006 - 84,362,606 (+)EnsemblGRCm39 Ensembl
GRCm381284,285,237 - 84,315,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,285,232 - 84,315,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,626,264 - 85,656,782 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361285,175,062 - 85,205,580 (+)NCBIMGSCv36mm8
Celera1285,740,324 - 85,770,857 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.14NCBI
Ptgr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,662,469 - 109,694,232 (+)NCBIGRCr8
mRatBN7.26103,931,367 - 103,963,113 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,931,409 - 103,963,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,093,166 - 104,124,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,392,251 - 104,423,987 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,761,828 - 103,793,565 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,999,832 - 108,031,645 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,999,846 - 108,031,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,514,752 - 117,546,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,349,172 - 108,380,867 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,352,627 - 108,384,321 (+)NCBI
Celera6101,759,837 - 101,791,510 (+)NCBICelera
Cytogenetic Map6q31NCBI
Ptgr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,515,017 - 1,549,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,519,767 - 1,549,998 (-)NCBIChiLan1.0ChiLan1.0
PTGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,941,609 - 74,981,970 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11474,158,124 - 74,191,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,410,939 - 54,444,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,266,484 - 73,299,378 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,266,502 - 73,299,378 (+)Ensemblpanpan1.1panPan2
PTGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,095,405 - 47,120,371 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,768,242 - 46,805,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,313,084 - 47,350,058 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl847,312,781 - 47,350,047 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,980,670 - 47,017,709 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,998,391 - 47,035,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,389,163 - 47,426,127 (+)NCBIUU_Cfam_GSD_1.0
PTGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,174,219 - 97,195,595 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,174,143 - 97,195,601 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,928,733 - 102,950,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,060,503 - 51,095,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2451,060,608 - 51,095,303 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605339,274,452 - 39,312,455 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptgr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473427,687,195 - 27,717,548 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473427,686,993 - 27,716,802 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000008582   ⟹   ENSSTOP00000007692
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364883,123,304 - 3,166,863 (+)Ensembl
RefSeq Acc Id: XM_005321216   ⟹   XP_005321273
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864028,903,412 - 28,945,615 (-)NCBI
SpeTri2.0NW_0049364883,123,405 - 3,165,556 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040275839   ⟹   XP_040131773
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864028,903,412 - 28,945,624 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005321273 (Get FASTA)   NCBI Sequence Viewer  
  XP_040131773 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000007692.3
GenBank Protein KAG3260720 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005321273   ⟸   XM_005321216
- Peptide Label: isoform X1
- UniProtKB: I3MBW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131773   ⟸   XM_040275839
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000007692   ⟸   ENSSTOT00000008582
Protein Domains
Alcohol dehydrogenase-like C-terminal   Oxidoreductase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008590 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008582.3 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro ADH_C UniProtKB/TrEMBL
  ADH_N_2 UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/TrEMBL
  MDR_fam UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  PTGR2 UniProtKB/TrEMBL
NCBI Gene Ptgr2 ENTREZGENE
PANTHER PROSTAGLANDIN REDUCTASE 2 UniProtKB/TrEMBL
  PTHR43205 UniProtKB/TrEMBL
Pfam ADH_N_2 UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt I3MBW5 ENTREZGENE, UniProtKB/TrEMBL