Potefam1 (POTE ankyrin domain family member 1) - Rat Genome Database

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Gene: Potefam1 (POTE ankyrin domain family member 1) Rattus norvegicus
Analyze
Symbol: Potefam1
Name: POTE ankyrin domain family member 1
RGD ID: 1309783
Description: Predicted to be located in membrane. Orthologous to human ANKRD30A (ankyrin repeat domain 30A); INTERACTS WITH 2-palmitoylglycerol (ortholog); aflatoxin B1 (ortholog); amosite asbestos (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ankrd30a; ankyrin repeat domain 30A; ankyrin repeat domain-containing protein 26-like; ankyrin repeat domain-containing protein 62; LOC102555149; LOC295999; POTE ankyrin domain family member A; putative ankyrin repeat domain-containing protein 19; RGD1309783; similar to RIKEN cDNA 4930430A15; uncharacterized protein Ankrd30a; uncharacterized protein LOC102555149; uncharacterized protein LOC295999; uncharacterized protein Potefam1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83118,095,804 - 118,281,502 (-)NCBIGRCr8
mRatBN7.2397,641,258 - 97,826,965 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl397,641,261 - 97,826,949 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03102,293,156 - 102,430,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03108,893,500 - 109,029,915 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4396,751,664 - 96,793,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1396,497,191 - 96,690,381 (-)NCBI
Celera396,798,527 - 96,832,247 (-)NCBICelera
Celera396,740,636 - 96,785,992 (-)NCBICelera
Cytogenetic Map3q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Potefam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83118,095,804 - 118,281,502 (-)NCBIGRCr8
mRatBN7.2397,641,258 - 97,826,965 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl397,641,261 - 97,826,949 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03102,293,156 - 102,430,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03108,893,500 - 109,029,915 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4396,751,664 - 96,793,953 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1396,497,191 - 96,690,381 (-)NCBI
Celera396,798,527 - 96,832,247 (-)NCBICelera
Celera396,740,636 - 96,785,992 (-)NCBICelera
Cytogenetic Map3q34NCBI
ANKRD30A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381037,125,598 - 37,265,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1037,125,598 - 37,232,567 (+)EnsemblGRCh38hg38GRCh38
GRCh371037,414,526 - 37,521,495 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361037,454,791 - 37,561,501 (+)NCBINCBI36Build 36hg18NCBI36
Build 341037,454,790 - 37,793,655NCBI
Celera1037,180,898 - 37,292,246 (+)NCBICelera
Cytogenetic Map10p11.21NCBI
HuRef1037,134,948 - 37,229,175 (+)NCBIHuRef
CHM1_11037,415,489 - 37,521,465 (+)NCBICHM1_1
T2T-CHM13v2.01037,157,689 - 37,308,527 (+)NCBIT2T-CHM13v2.0
Potefam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392110,880,755 - 111,059,948 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2110,880,755 - 111,059,948 (-)EnsemblGRCm39 Ensembl
GRCm382111,050,410 - 111,229,603 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2111,134,114 - 111,152,936 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl2111,088,372 - 111,105,982 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl2111,162,061 - 111,229,602 (-)EnsemblGRCm38mm10GRCm38
MGSCv372111,033,411 - 111,069,757 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362110,994,093 - 111,030,437 (-)NCBIMGSCv36mm8
Celera2112,349,393 - 112,385,775 (-)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.75NCBI
Ankrd30a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955546798,445 - 890,288 (+)NCBIChiLan1.0ChiLan1.0
LOC100971897
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21723,264,246 - 23,313,043 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,956,841 - 9,005,638 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02193,572 - 141,501 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11037,800,725 - 37,918,835 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1037,800,725 - 37,884,355 (+)Ensemblpanpan1.1panPan2
LOC101971738
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721384,400,865 - 84,510,969 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366172,273,033 - 2,383,120 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103215727
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1936,843,594 - 36,857,290 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366697817,528 - 24,868 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Potefam1
801 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)396127817102200699Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat

Markers in Region
D3Rat70  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2397,782,964 - 97,783,166 (+)MAPPERmRatBN7.2
Rnor_6.03102,386,307 - 102,386,506NCBIRnor6.0
Rnor_5.03108,986,651 - 108,986,850UniSTSRnor5.0
RH 3.4 Map3781.39RGD
RH 3.4 Map3781.39UniSTS
RH 2.0 Map3522.3RGD
SHRSP x BN Map349.5398RGD
FHH x ACI Map357.25RGD
Cytogenetic Map3q34UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000107600   ⟹   ENSRNOP00000086476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl397,641,261 - 97,826,949 (-)Ensembl
RefSeq Acc Id: XM_039106462   ⟹   XP_038962390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83118,095,804 - 118,281,502 (-)NCBI
mRatBN7.2397,641,258 - 97,826,965 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038962390 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79772 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000086476
  ENSRNOP00000086476.1
Reference Protein Sequences
RefSeq Acc Id: XP_038962390   ⟸   XM_039106462
- UniProtKB: A0A8I6A697 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000086476   ⟸   ENSRNOT00000107600
Protein Domains
DUF3496

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309783 AgrOrtholog
BioCyc Gene G2FUF-48458 BioCyc
Ensembl Genes ENSRNOG00000064354 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000107600.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  DUF3496 UniProtKB/TrEMBL
NCBI Gene 295999 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN 36-RELATED UniProtKB/TrEMBL
  POTE ANKYRIN DOMAIN FAMILY, MEMBER G-LIKE UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  DUF3496 UniProtKB/TrEMBL
PhenoGen Potefam1 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000064354 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8I6A697 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-03 Potefam1  POTE ankyrin domain family member 1  Ankrd30a  ankyrin repeat domain 30A  Name and Symbol changed 629549 APPROVED
2022-03-03 Ankrd30a  ankyrin repeat domain 30A  Ankrd30a  ankyrin repeat domain 30A  Data merged from RGD:149736448 737654 PROVISIONAL
2021-08-09 Ankrd30a  ankyrin repeat domain 30A      Symbol and Name status set to provisional 45752 PROVISIONAL
2021-03-09 Ankrd30a  ankyrin repeat domain 30A  LOC102555149  ankyrin repeat domain-containing protein 26-like  Data merged from RGD:7546965 737654 PROVISIONAL
2016-03-01 Ankrd30a  ankyrin repeat domain 30A  RGD1309783  similar to RIKEN cDNA 4930430A15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102555149  ankyrin repeat domain-containing protein 26-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1309783  similar to RIKEN cDNA 4930430A15   RGD1309783_predicted  similar to RIKEN cDNA 4930430A15 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1309783_predicted  similar to RIKEN cDNA 4930430A15 (predicted)  LOC295999_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC295999_predicted  similar to RIKEN cDNA 4930430A15 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL