Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tcf25 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tcf25 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TCF25 mRNA | CTD | PMID:22206623 | Tcf25 | Rat | 17beta-estradiol | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of TCF25 mRNA | CTD | PMID:16474171 | Tcf25 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tcf25 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TCF25 mRNA | CTD | PMID:21570461 and PMID:24058054 | Tcf25 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TCF25 mRNA | CTD | PMID:33387578 | Tcf25 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tcf25 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to TCF25 promoter] | CTD | PMID:19654925 | Tcf25 | Rat | 2-methylcholine | affects expression | ISO | TCF25 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of TCF25 mRNA | CTD | PMID:21179406 | Tcf25 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Tcf25 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of TCF25 mRNA | CTD | PMID:20188158 | Tcf25 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TCF25 mRNA more ... | CTD | PMID:28628672 | Tcf25 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of TCF25 mRNA | CTD | PMID:28628672 | Tcf25 | Rat | acrolein | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TCF25 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TCF25 mRNA | CTD | PMID:32699268 | Tcf25 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of TCF25 mRNA | CTD | PMID:28959563 | Tcf25 | Rat | aflatoxin B1 | decreases methylation | ISO | TCF25 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TCF25 intron | CTD | PMID:30157460 | Tcf25 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | TCF25 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of TCF25 intron | CTD | PMID:30157460 | Tcf25 | Rat | alpha-pinene | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TCF25 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TCF25 mRNA | CTD | PMID:32699268 | Tcf25 | Rat | Aroclor 1254 | decreases expression | ISO | Tcf25 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TCF25 mRNA | CTD | PMID:23650126 | Tcf25 | Rat | benzo[e]pyrene | decreases methylation | ISO | TCF25 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of TCF25 intron | CTD | PMID:30157460 | Tcf25 | Rat | bisphenol A | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TCF25 mRNA | CTD | PMID:16474171 | Tcf25 | Rat | bisphenol A | increases expression | ISO | TCF25 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TCF25 mRNA | CTD | PMID:33670352 | Tcf25 | Rat | bisphenol A | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TCF25 mRNA | CTD | PMID:28628672 | Tcf25 | Rat | bisphenol A | affects methylation | ISO | Tcf25 (Mus musculus) | 6480464 | bisphenol A affects the methylation of TCF25 promoter | CTD | PMID:27334623 | Tcf25 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TCF25 mRNA | CTD | PMID:30816183 | Tcf25 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TCF25 mRNA | CTD | PMID:25181051 | Tcf25 | Rat | bisphenol F | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of TCF25 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TCF25 mRNA | CTD | PMID:28628672 and PMID:31601247 | Tcf25 | Rat | cadmium atom | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TCF25 mRNA | CTD | PMID:35301059 | Tcf25 | Rat | cadmium dichloride | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TCF25 mRNA | CTD | PMID:35301059 | Tcf25 | Rat | CGP 52608 | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NULP1 gene] | CTD | PMID:28238834 | Tcf25 | Rat | coumarin | decreases phosphorylation | ISO | TCF25 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of TCF25 protein | CTD | PMID:35688186 | Tcf25 | Rat | cytarabine | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of TCF25 mRNA | CTD | PMID:21198554 | Tcf25 | Rat | dexamethasone | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TCF25 mRNA more ... | CTD | PMID:28628672 | Tcf25 | Rat | Dibutyl phosphate | affects expression | ISO | TCF25 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TCF25 mRNA | CTD | PMID:37042841 | Tcf25 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of TCF25 mRNA | CTD | PMID:24893172 | Tcf25 | Rat | dorsomorphin | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TCF25 mRNA | CTD | PMID:27188386 | Tcf25 | Rat | ethanol | multiple interactions | ISO | Tcf25 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of TCF25 mRNA | CTD | PMID:30319688 | Tcf25 | Rat | folic acid | multiple interactions | ISO | Tcf25 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TCF25 mRNA | CTD | PMID:22206623 | Tcf25 | Rat | fulvestrant | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of TCF25 gene | CTD | PMID:31601247 | Tcf25 | Rat | genistein | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Genistein results in decreased expression of TCF25 mRNA | CTD | PMID:16474171 | Tcf25 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TCF25 mRNA | CTD | PMID:33387578 | Tcf25 | Rat | geraniol | increases expression | ISO | TCF25 (Homo sapiens) | 6480464 | geraniol results in increased expression of TCF25 mRNA | CTD | PMID:27683099 | Tcf25 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of TCF25 mRNA | CTD | PMID:24136188 | Tcf25 | Rat | hydrogen cyanide | decreases expression | ISO | Tcf25 (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of TCF25 mRNA | CTD | PMID:33914522 | Tcf25 | Rat | indometacin | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TCF25 mRNA more ... | CTD | PMID:28628672 | Tcf25 | Rat | ivermectin | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TCF25 protein | CTD | PMID:32959892 | Tcf25 | Rat | methapyrilene | decreases methylation | ISO | TCF25 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of TCF25 intron | CTD | PMID:30157460 | Tcf25 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TCF25 gene | CTD | PMID:35440735 | Tcf25 | Rat | methylmercury chloride | increases expression | ISO | TCF25 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TCF25 mRNA | CTD | PMID:28001369 | Tcf25 | Rat | methylmercury chloride | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of TCF25 mRNA | CTD | PMID:28001369 | Tcf25 | Rat | nickel sulfate | increases expression | ISO | TCF25 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of TCF25 mRNA | CTD | PMID:22714537 | Tcf25 | Rat | ozone | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TCF25 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | Tcf25 | Rat | p-chloromercuribenzoic acid | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of TCF25 mRNA | CTD | PMID:26272509 | Tcf25 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TCF25 mRNA | CTD | PMID:27188386 | Tcf25 | Rat | phenobarbital | affects expression | ISO | Tcf25 (Mus musculus) | 6480464 | Phenobarbital affects the expression of TCF25 mRNA | CTD | PMID:23091169 | Tcf25 | Rat | potassium cyanide | increases expression | ISO | Tcf25 (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of TCF25 mRNA | CTD | PMID:33914522 | Tcf25 | Rat | progesterone | affects expression | ISO | Tcf25 (Mus musculus) | 6480464 | Progesterone affects the expression of TCF25 mRNA | CTD | PMID:17251523 | Tcf25 | Rat | propiconazole | decreases expression | ISO | Tcf25 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TCF25 mRNA | CTD | PMID:21278054 | Tcf25 | Rat | SB 431542 | multiple interactions | ISO | TCF25 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TCF25 mRNA | CTD | PMID:27188386 | Tcf25 | Rat | silicon dioxide | increases expression | ISO | Tcf25 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of TCF25 mRNA | CTD | PMID:19073995 | Tcf25 | Rat | silicon dioxide | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of TCF25 mRNA | CTD | PMID:25351596 | Tcf25 | Rat | sodium arsenite | increases expression | ISO | Tcf25 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of TCF25 mRNA | CTD | PMID:32068019 | Tcf25 | Rat | testosterone enanthate | affects expression | ISO | TCF25 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of TCF25 mRNA | CTD | PMID:17440010 | Tcf25 | Rat | tetrodotoxin | increases expression | ISO | Tcf25 (Mus musculus) | 6480464 | Tetrodotoxin results in increased expression of TCF25 mRNA | CTD | PMID:26436198 | Tcf25 | Rat | thapsigargin | increases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of TCF25 mRNA | CTD | PMID:22378314 | Tcf25 | Rat | triphenyl phosphate | affects expression | ISO | TCF25 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TCF25 mRNA | CTD | PMID:37042841 | Tcf25 | Rat | tunicamycin | increases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of TCF25 mRNA | CTD | PMID:22378314 | Tcf25 | Rat | valproic acid | decreases expression | ISO | TCF25 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TCF25 mRNA | CTD | PMID:29154799 | Tcf25 | Rat | valproic acid | increases methylation | ISO | TCF25 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TCF25 gene | CTD | PMID:29154799 | Tcf25 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of TCF25 mRNA | CTD | PMID:19015723 | |