Osgep (O-sialoglycoprotein endopeptidase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Osgep (O-sialoglycoprotein endopeptidase) Rattus norvegicus
Analyze
Symbol: Osgep
Name: O-sialoglycoprotein endopeptidase
RGD ID: 1308578
Description: Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 3. Orthologous to human OSGEP (O-sialoglycoprotein endopeptidase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC290028; N6-L-threonylcarbamoyladenine synthase; O-sialoglycoprotease; pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1; probable O-sialoglycoprotein endopeptidase; probable tRNA N6-adenosine threonylcarbamoyltransferase; probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep; Prsmg1/Gcpl1; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep; tRNA N6-adenosine threonylcarbamoyltransferase; tRNA threonylcarbamoyladenosine biosynthesis protein Osgep
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,610,694 - 26,618,113 (-)NCBIGRCr8
mRatBN7.21524,137,149 - 24,144,568 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,137,153 - 24,144,568 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,908,335 - 26,915,754 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,867,039 - 27,874,458 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,116,878 - 26,124,297 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,842,447 - 27,849,866 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,842,422 - 27,849,974 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,674,872 - 31,682,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,896,592 - 26,904,011 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,912,465 - 26,919,623 (-)NCBI
Celera1524,457,277 - 24,464,696 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRatGalloway-Mowat syndrome  ISOOSGEP (Homo sapiens)8554872ClinVar Annotator: match by term: Galloway-Mowat syndromeClinVarPMID:17897280 more ...
OsgepRatGalloway-Mowat syndrome 3  ISOOSGEP (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11519896 more ...
OsgepRatgenetic disease  ISOOSGEP (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:16199547 more ...
OsgepRatnephrotic syndrome  ISOOSGEP (Homo sapiens)8554872ClinVar Annotator: match by term: Nephrotic syndromeClinVarPMID:11519896 more ...
OsgepRatpurine nucleoside phosphorylase deficiency  ISOOSGEP (Homo sapiens)8554872ClinVar Annotator: match by term: Purine-nucleoside phosphorylase deficiencyClinVarPMID:24767876 and PMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRatGalloway-Mowat syndrome  ISOOSGEP (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28805828
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRatGalloway-Mowat syndrome 3  ISOOSGEP (Homo sapiens)7240710 OMIM 

1 to 20 of 52 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRat(-)-epigallocatechin 3-gallate multiple interactionsISOOSGEP (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of OSGEP mRNACTDPMID:22079256
OsgepRat(1->4)-beta-D-glucan multiple interactionsISOOsgep (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of OSGEP mRNACTDPMID:36331819
OsgepRat1,2-dimethylhydrazine multiple interactionsISOOsgep (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of OSGEP mRNACTDPMID:22206623
OsgepRat2,2',4,4'-Tetrabromodiphenyl ether increases expressionISOOSGEP (Homo sapiens)64804642 more ...CTDPMID:31675489
OsgepRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOOsgep (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of OSGEP mRNACTDPMID:21570461
OsgepRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of OSGEP mRNACTDPMID:33387578
OsgepRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOOSGEP (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of OSGEP mRNACTDPMID:28628672
OsgepRat4,4'-diaminodiphenylmethane increases expressionISOOsgep (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of OSGEP mRNACTDPMID:18648102
OsgepRat4-hydroxyphenyl retinamide decreases expressionISOOsgep (Mus musculus)6480464Fenretinide results in decreased expression of OSGEP mRNACTDPMID:28973697
OsgepRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of OSGEP mRNACTDPMID:16483693
OsgepRataristolochic acid A increases expressionISOOSGEP (Homo sapiens)6480464aristolochic acid I results in increased expression of OSGEP proteinCTDPMID:33212167
OsgepRatarsane affects methylationISOOSGEP (Homo sapiens)6480464Arsenic affects the methylation of OSGEP geneCTDPMID:25304211
OsgepRatarsenic atom affects methylationISOOSGEP (Homo sapiens)6480464Arsenic affects the methylation of OSGEP geneCTDPMID:25304211
OsgepRatarsenite(3-) multiple interactionsISOOSGEP (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to OSGEP mRNA]CTDPMID:32406909
OsgepRatatrazine decreases expressionISOOSGEP (Homo sapiens)6480464Atrazine results in decreased expression of OSGEP mRNACTDPMID:22378314
OsgepRatbisphenol A decreases expressionISOOSGEP (Homo sapiens)6480464bisphenol A results in decreased expression of OSGEP mRNA and bisphenol A results in decreased expression of OSGEP proteinCTDPMID:25047013 more ...
OsgepRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of OSGEP mRNACTDPMID:34947998
OsgepRatbisphenol A multiple interactionsISOOSGEP (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of OSGEP mRNACTDPMID:28628672
OsgepRatbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of OSGEP mRNACTDPMID:25181051
OsgepRatbutan-1-ol multiple interactionsISOOSGEP (Homo sapiens)6480464[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of OSGEP mRNACTDPMID:29432896

1 to 20 of 52 rows

Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRattRNA modification involved_inISOOSGEP (Homo sapiens)1624291 PMID:28805828RGDPMID:28805828
OsgepRattRNA modification involved_inIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRattRNA modification involved_inIEAARBA:ARBA000271661600115GO_REF:0000117UniProtGO_REF:0000117
OsgepRattRNA processing involved_inIEAUniProtKB-KW:KW-08191600115GO_REF:0000043UniProtGO_REF:0000043
OsgepRattRNA threonylcarbamoyladenosine metabolic process involved_inIEAARBA:ARBA000282421600115GO_REF:0000117UniProtGO_REF:0000117
OsgepRattRNA threonylcarbamoyladenosine modification involved_inISSUniProtKB:Q9NPF41600115GO_REF:0000024UniProtGO_REF:0000024
OsgepRattRNA threonylcarbamoyladenosine modification involved_inIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRattRNA threonylcarbamoyladenosine modification involved_inIEAInterPro:IPR0346801600115GO_REF:0000002InterProGO_REF:0000002
OsgepRattRNA threonylcarbamoyladenosine modification involved_inIEAUniRule:UR0001659061600115GO_REF:0000104UniProtGO_REF:0000104
OsgepRattRNA threonylcarbamoyladenosine modification involved_inISOOSGEP (Homo sapiens)1624291 PMID:28805828 and PMID:31481669RGDPMID:28805828 and PMID:31481669
1 to 10 of 10 rows

Cellular Component
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRatcytoplasm located_inISSUniProtKB:Q9NPF41600115GO_REF:0000024UniProtGO_REF:0000024
OsgepRatcytoplasm located_inIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRatcytoplasm located_inIEAUniRule:UR0001659061600115GO_REF:0000104UniProtGO_REF:0000104
OsgepRatcytoplasm is_active_inIBAPANTHER:PTN000200096 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
OsgepRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
OsgepRatcytoplasm located_inISOOSGEP (Homo sapiens)1624291 PMID:28805828RGDPMID:28805828
OsgepRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
OsgepRatcytosol located_inISOOSGEP (Homo sapiens)1624291 RGDGO_REF:0000052
OsgepRatcytosol located_inIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRatEKC/KEOPS complex part_ofIEAInterPro:IPR0346801600115GO_REF:0000002InterProGO_REF:0000002
OsgepRatEKC/KEOPS complex part_ofIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRatEKC/KEOPS complex part_ofIBAPANTHER:PTN000200096 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
OsgepRatEKC/KEOPS complex part_ofISOOSGEP (Homo sapiens)1624291 PMID:27903914 more ...RGDPMID:27903914 more ...
OsgepRatEKC/KEOPS complex part_ofISSUniProtKB:Q9NPF41600115GO_REF:0000024UniProtGO_REF:0000024
OsgepRatnucleoplasm located_inISOOSGEP (Homo sapiens)1624291 RGDGO_REF:0000052
OsgepRatnucleoplasm located_inIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
OsgepRatnucleus located_inIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
OsgepRatnucleus located_inISOOSGEP (Homo sapiens)1624291 PMID:27903914 and PMID:28805828RGDPMID:27903914 and PMID:28805828
1 to 20 of 21 rows

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OsgepRatacyltransferase activity enablesIEAUniProtKB-KW:KW-00121600115GO_REF:0000043UniProtGO_REF:0000043
OsgepRatacyltransferase activity, transferring groups other than amino-acyl groups enablesIEAUniRule:UR0001659061600115GO_REF:0000104UniProtGO_REF:0000104
OsgepRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
OsgepRatN(6)-L-threonylcarbamoyladenine synthase activity enablesISOOSGEP (Homo sapiens)1624291 PMID:28805828RGDPMID:28805828
OsgepRatN(6)-L-threonylcarbamoyladenine synthase activity enablesIEAEC:2.3.1.2341600115GO_REF:0000003UniProtGO_REF:0000003
OsgepRatN(6)-L-threonylcarbamoyladenine synthase activity enablesIEARHEA:370591600115GO_REF:0000116RHEAGO_REF:0000116
OsgepRatN(6)-L-threonylcarbamoyladenine synthase activity enablesIEAUniProtKB:Q9NPF4 and ensembl:ENSP000002065421600115GO_REF:0000107EnsemblGO_REF:0000107
OsgepRatprotein binding enablesISOOSGEP (Homo sapiens)1624291UniProtKB:O95817 more ...RGDPMID:23414517 more ...
OsgepRattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8086453   PMID:10631378   PMID:12477932   PMID:27903914   PMID:28805828  



Osgep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,610,694 - 26,618,113 (-)NCBIGRCr8
mRatBN7.21524,137,149 - 24,144,568 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,137,153 - 24,144,568 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,908,335 - 26,915,754 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,867,039 - 27,874,458 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,116,878 - 26,124,297 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,842,447 - 27,849,866 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,842,422 - 27,849,974 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,674,872 - 31,682,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,896,592 - 26,904,011 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,912,465 - 26,919,623 (-)NCBI
Celera1524,457,277 - 24,464,696 (-)NCBICelera
Cytogenetic Map15p14NCBI
OSGEP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,446,401 - 20,454,812 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,446,401 - 20,455,089 (-)EnsemblGRCh38hg38GRCh38
GRCh371420,914,560 - 20,922,971 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,985,056 - 19,993,038 (-)NCBINCBI36Build 36hg18NCBI36
Build 341419,985,055 - 19,993,038NCBI
Celera14776,357 - 784,417 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,036,962 - 1,044,886 (-)NCBIHuRef
CHM1_11420,916,587 - 20,924,647 (-)NCBICHM1_1
T2T-CHM13v2.01414,643,301 - 14,651,715 (-)NCBIT2T-CHM13v2.0
Osgep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,152,831 - 51,162,350 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,143,935 - 51,162,350 (-)EnsemblGRCm39 Ensembl
GRCm381450,915,374 - 50,924,893 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,906,478 - 50,924,893 (-)EnsemblGRCm38mm10GRCm38
MGSCv371451,535,049 - 51,544,568 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,837,325 - 49,846,844 (-)NCBIMGSCv36mm8
Celera1447,206,136 - 47,224,482 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.3NCBI
Osgep
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,265,401 - 1,273,299 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,266,191 - 1,273,093 (-)NCBIChiLan1.0ChiLan1.0
OSGEP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21521,956,556 - 21,964,635 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,173,043 - 21,181,122 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,321,599 - 1,329,604 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,373,836 - 19,381,888 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,373,836 - 19,381,888 (-)Ensemblpanpan1.1panPan2
OSGEP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,780,474 - 17,786,452 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,780,476 - 17,811,173 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,263,462 - 18,269,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,037,539 - 18,043,534 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,037,541 - 18,043,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,720,433 - 17,726,396 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,775,053 - 17,781,030 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,904,232 - 17,910,209 (-)NCBIUU_Cfam_GSD_1.0
Osgep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864077,678,727 - 77,685,347 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936877659,874 - 666,026 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936877659,881 - 666,169 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSGEP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,454,666 - 78,462,258 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,454,667 - 78,462,260 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,482,276 - 83,490,100 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OSGEP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12920,960,710 - 20,969,321 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2920,960,378 - 20,968,903 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,451,480 - 25,460,413 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osgep
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248254,714,993 - 4,721,884 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248254,715,133 - 4,721,884 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:92
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000012790
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat

1 to 10 of 25 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000012790   ⟹   ENSRNOP00000012789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1524,137,153 - 24,144,568 (-)Ensembl
Rnor_6.0 Ensembl1527,842,422 - 27,849,974 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097357   ⟹   ENSRNOP00000092779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1524,137,153 - 24,144,537 (-)Ensembl
RefSeq Acc Id: NM_001100510   ⟹   NP_001093980
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,610,694 - 26,618,113 (-)NCBI
mRatBN7.21524,137,149 - 24,144,568 (-)NCBI
Rnor_6.01527,842,447 - 27,849,866 (-)NCBI
Rnor_5.01531,674,872 - 31,682,291 (-)NCBI
RGSC_v3.41526,896,592 - 26,904,011 (-)RGD
Celera1524,457,277 - 24,464,696 (-)RGD
Sequence:
RefSeq Acc Id: XM_039093106   ⟹   XP_038949034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,610,694 - 26,618,037 (-)NCBI
mRatBN7.21524,137,149 - 24,144,553 (-)NCBI
RefSeq Acc Id: XM_063274101   ⟹   XP_063130171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,610,694 - 26,618,044 (-)NCBI
RefSeq Acc Id: XR_005493700
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,612,241 - 26,618,041 (-)NCBI
mRatBN7.21524,137,149 - 24,144,559 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001093980 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949034 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130171 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58593 (Get FASTA)   NCBI Sequence Viewer  
  BAA82123 (Get FASTA)   NCBI Sequence Viewer  
  EDL88424 (Get FASTA)   NCBI Sequence Viewer  
  EDL88425 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012789
  ENSRNOP00000012789.4
GenBank Protein Q9WVS2 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_001093980   ⟸   NM_001100510
- UniProtKB: B0BMW7 (UniProtKB/Swiss-Prot),   Q9WVS2 (UniProtKB/Swiss-Prot),   A0A8I6AEB6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012789   ⟸   ENSRNOT00000012790
RefSeq Acc Id: XP_038949034   ⟸   XM_039093106
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000092779   ⟸   ENSRNOT00000097357
RefSeq Acc Id: XP_063130171   ⟸   XM_063274101
- Peptide Label: isoform X1
Gcp-like

Name Modeler Protein Id AA Range Protein Structure
AF-Q9WVS2-F1-model_v2 AlphaFold Q9WVS2 1-335 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699624
Promoter ID:EPDNEW_R10146
Type:initiation region
Name:Osgep_1
Description:O-sialoglycoprotein endopeptidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01527,849,891 - 27,849,951EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14052 BioCyc
Ensembl Genes ENSRNOG00000009333 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012790 ENTREZGENE
  ENSRNOT00000012790.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126956 IMAGE-MGC_LOAD
  IMAGE:8362956 IMAGE-MGC_LOAD
InterPro ATPase_NBD UniProtKB/Swiss-Prot
  Gcp-like_dom UniProtKB/Swiss-Prot
  Kae1/OSGEP UniProtKB/Swiss-Prot
  KAE1/TsaD UniProtKB/Swiss-Prot
  Peptidase_M22_CS UniProtKB/Swiss-Prot
KEGG Report rno:290028 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187386 IMAGE-MGC_LOAD
  MGC:95102 IMAGE-MGC_LOAD
NCBI Gene 290028 ENTREZGENE
PANTHER PTHR11735 UniProtKB/Swiss-Prot
  PTHR11735:SF14 UniProtKB/Swiss-Prot
Pfam Peptidase_M22 UniProtKB/Swiss-Prot
PhenoGen Osgep PhenoGen
PRINTS OSIALOPTASE UniProtKB/Swiss-Prot
PROSITE GLYCOPROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009333 RatGTEx
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot
UniProt A0A8I6AEB6 ENTREZGENE, UniProtKB/TrEMBL
  A6KEC0_RAT UniProtKB/TrEMBL
  B0BMW7 ENTREZGENE
  OSGEP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B0BMW7 UniProtKB/Swiss-Prot
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Osgep  O-sialoglycoprotein endopeptidase  Osgep_predicted  O-sialoglycoprotein endopeptidase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Osgep_predicted  O-sialoglycoprotein endopeptidase (predicted)      Symbol and Name status set to approved 70820 APPROVED