Pard6b (par-6 family cell polarity regulator beta) - Rat Genome Database

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Gene: Pard6b (par-6 family cell polarity regulator beta) Rattus norvegicus
Analyze
Symbol: Pard6b
Name: par-6 family cell polarity regulator beta
RGD ID: 1308205
Description: Predicted to be involved in several processes, including centrosome cycle; establishment or maintenance of cell polarity; and protein-containing complex assembly. Part of protein-containing complex. Orthologous to human PARD6B (par-6 family cell polarity regulator beta); PARTICIPATES IN protein kinase C (PKC) signaling pathway; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362279; par-6 (partitioning defective 6) homolog beta; par-6 (partitioning defective 6) homolog beta (C. elegans); partitioning defective 6 homolog beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Celera3155,366,567 - 155,386,818 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pard6bRatautism spectrum disorder  ISOPARD6B (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:35663546

1 to 20 of 86 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pard6bRat1,2-dimethylhydrazine decreases expressionISOPard6b (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PARD6B mRNACTDPMID:22206623
Pard6bRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPARD6B (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of PARD6B mRNACTDPMID:22298810
Pard6bRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PARD6B mRNACTDPMID:33387578
Pard6bRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPard6b (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PARD6B mRNACTDPMID:21570461
Pard6bRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of PARD6B mRNACTDPMID:21346803
Pard6bRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of PARD6B mRNACTDPMID:21346803
Pard6bRat2-hydroxypropanoic acid decreases expressionISOPARD6B (Homo sapiens)6480464Lactic Acid results in decreased expression of PARD6B mRNACTDPMID:30851411
Pard6bRat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of PARD6B proteinCTDPMID:34915118
Pard6bRat3-methylcholanthrene decreases expressionISOPard6b (Mus musculus)6480464Methylcholanthrene results in decreased expression of PARD6B mRNACTDPMID:20713471
Pard6bRat3-methylcholanthrene multiple interactionsISOPard6b (Mus musculus)6480464[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNACTDPMID:23519560
Pard6bRat4-hydroxyphenyl retinamide decreases expressionISOPard6b (Mus musculus)6480464Fenretinide results in decreased expression of PARD6B mRNACTDPMID:28973697
Pard6bRat4-hydroxyphenyl retinamide increases expressionISOPard6b (Mus musculus)6480464Fenretinide results in increased expression of PARD6B mRNACTDPMID:28973697
Pard6bRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PARD6B mRNACTDPMID:30047161
Pard6bRatacrolein multiple interactionsISOPARD6B (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PARD6B mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PARD6B mRNACTDPMID:32699268
Pard6bRatacrylamide increases expressionISOPARD6B (Homo sapiens)6480464Acrylamide results in increased expression of PARD6B mRNACTDPMID:32763439
Pard6bRataflatoxin B1 increases methylationISOPARD6B (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PARD6B geneCTDPMID:27153756
Pard6bRatall-trans-retinoic acid increases expressionISOPARD6B (Homo sapiens)6480464Tretinoin results in increased expression of PARD6B mRNACTDPMID:33167477
Pard6bRatalpha-pinene multiple interactionsISOPARD6B (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PARD6B mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PARD6B mRNACTDPMID:32699268
Pard6bRatamitrole increases expressionEXP 6480464Amitrole results in increased expression of PARD6B mRNACTDPMID:30047161
Pard6bRatamphetamine decreases expressionEXP 6480464Amphetamine results in decreased expression of PARD6B mRNACTDPMID:30779732

1 to 20 of 86 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pard6bRatcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Pard6bRatcentrosome cycle involved_inIBAPANTHER:PTN001019969 and UniProtKB:Q9NPB61600115GO_REF:0000033GO_CentralGO_REF:0000033
Pard6bRatestablishment or maintenance of cell polarity involved_inIBAPANTHER:PTN001019968 and UniProtKB:Q9NPB61600115GO_REF:0000033GO_CentralGO_REF:0000033
Pard6bRatprotein-containing complex assembly involved_inISOPARD6B (Homo sapiens)1624291 PMID:12545177RGDPMID:12545177
Pard6bRatprotein-containing complex assembly involved_inIEAUniProtKB:Q9BYG5 and ensembl:ENSP000003606721600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatregulation of cellular localization involved_inIBAMGI:1927223 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component
1 to 20 of 29 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pard6bRatanchoring junction located_inIEAUniProtKB-KW:KW-09651600115GO_REF:0000043UniProtGO_REF:0000043
Pard6bRatapical part of cell located_inISOPard6b (Mus musculus)1624291 PMID:15950600 and PMID:34166821RGDPMID:15950600 and PMID:34166821
Pard6bRatapical part of cell located_inIEAUniProtKB:Q9JK83 and ensembl:ENSMUSP000000526191600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatapical plasma membrane is_active_inIBAMGI:2135605 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pard6bRatapical plasma membrane located_inIEAUniProtKB:Q9JK83 and ensembl:ENSMUSP000000526191600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatapical plasma membrane located_inISOPard6b (Mus musculus)1624291 PMID:22333836RGDPMID:22333836
Pard6bRatbicellular tight junction located_inISOPARD6B (Homo sapiens)1624291 PMID:12545177RGDPMID:12545177
Pard6bRatbicellular tight junction located_inIEAUniProtKB:Q9BYG5 and ensembl:ENSP000003606721600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatbicellular tight junction located_inIEAUniProtKB-KW:KW-07961600115GO_REF:0000043UniProtGO_REF:0000043
Pard6bRatbicellular tight junction located_inIEAUniProtKB-SubCell:SL-02651600115GO_REF:0000044UniProtGO_REF:0000044
Pard6bRatbicellular tight junction located_inISOPard6b (Mus musculus)1624291 PMID:15950600RGDPMID:15950600
Pard6bRatbicellular tight junction located_inIEAUniProtKB:Q9JK83 and ensembl:ENSMUSP000000526191600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatcell cortex located_inISOPard6b (Mus musculus)1624291 PMID:15950600RGDPMID:15950600
Pard6bRatcell cortex is_active_inIBAMGI:1927223 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pard6bRatcell cortex located_inIEAUniProtKB:Q9JK83 and ensembl:ENSMUSP000000526191600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatcell junction located_inISOPARD6B (Homo sapiens) and UniProtKB:Q9BYG5-11624291 RGDGO_REF:0000052
Pard6bRatcell junction located_inIEAUniProtKB:Q9BYG5 and ensembl:ENSP000003606721600115GO_REF:0000107EnsemblGO_REF:0000107
Pard6bRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Pard6bRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Pard6bRatcytosol located_inISOPARD6B (Homo sapiens) and UniProtKB:Q9BYG5-11624291 RGDGO_REF:0000052
1 to 20 of 29 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pard6bRatprotein kinase C (PKC) signaling pathway   ISOPARD6B (Homo sapiens)5132275 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pard6bRatendocytosis pathway  IEA 6907045 KEGGrno:04144

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The PAR-aPKC system: lessons in polarity. Suzuki A and Ohno S, J Cell Sci. 2006 Mar 15;119(Pt 6):979-87.
7. Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Wong EW, etal., Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9657-62. Epub 2008 Jul 10.
PMID:12545177   PMID:15950600   PMID:19056867   PMID:19620967   PMID:22333836  



Pard6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Celera3155,366,567 - 155,386,818 (+)NCBICelera
Cytogenetic Map3q42NCBI
PARD6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382050,731,580 - 50,753,741 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2050,731,580 - 50,756,795 (+)EnsemblGRCh38hg38GRCh38
GRCh372049,348,117 - 49,370,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,781,488 - 48,803,685 (+)NCBINCBI36Build 36hg18NCBI36
Build 342048,781,730 - 48,800,432NCBI
Celera2046,052,360 - 46,074,607 (+)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2046,096,474 - 46,118,701 (+)NCBIHuRef
CHM1_12049,253,147 - 49,275,696 (+)NCBICHM1_1
T2T-CHM13v2.02052,501,886 - 52,524,081 (+)NCBIT2T-CHM13v2.0
Pard6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392167,922,924 - 167,943,123 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2167,922,924 - 167,943,123 (+)EnsemblGRCm39 Ensembl
GRCm382168,081,004 - 168,101,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2168,081,004 - 168,101,203 (+)EnsemblGRCm38mm10GRCm38
MGSCv372167,906,504 - 167,926,703 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362167,772,490 - 167,790,415 (+)NCBIMGSCv36mm8
Celera2174,023,444 - 174,043,724 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map288.24NCBI
Pard6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554457,625,303 - 7,638,654 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554457,625,303 - 7,638,652 (-)NCBIChiLan1.0ChiLan1.0
PARD6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,480,187 - 56,502,616 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,473,355 - 56,495,732 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02047,076,007 - 47,098,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12048,203,994 - 48,223,814 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2048,203,900 - 48,229,376 (+)Ensemblpanpan1.1panPan2
PARD6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12437,108,441 - 37,122,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,349,345 - 36,365,076 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02437,816,193 - 37,832,591 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,816,255 - 37,832,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12437,052,429 - 37,068,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,186,155 - 37,201,876 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,730,480 - 37,746,871 (+)NCBIUU_Cfam_GSD_1.0
Pard6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640188,500,105 - 188,519,486 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365143,953,753 - 3,966,312 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365143,953,748 - 3,967,871 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARD6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1752,195,041 - 52,213,843 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11752,195,360 - 52,211,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21758,650,703 - 58,651,538 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21758,583,393 - 58,588,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARD6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,218,514 - 13,239,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,215,929 - 13,237,421 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605061,648,766 - 61,668,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pard6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247904,939,592 - 4,960,531 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247904,939,753 - 4,960,432 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pard6b
100 total Variants

Predicted Target Of
Summary Value
Count of predictions:479
Count of miRNA genes:257
Interacting mature miRNAs:311
Transcripts:ENSRNOT00000014568
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 36 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat

1 to 10 of 36 rows
RH136841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23156,811,291 - 156,811,423 (+)MAPPERmRatBN7.2
Rnor_6.03164,843,067 - 164,843,198NCBIRnor6.0
Rnor_5.03170,989,931 - 170,990,062UniSTSRnor5.0
RGSC_v3.43159,251,427 - 159,251,558UniSTSRGSC3.4
Celera3155,386,490 - 155,386,621UniSTS
RH 3.4 Map31480.7UniSTS
Cytogenetic Map3q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


RefSeq Transcripts NM_001108609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000014568   ⟹   ENSRNOP00000014568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)Ensembl
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)Ensembl
RefSeq Acc Id: NM_001108609   ⟹   NP_001102079
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83177,209,429 - 177,230,509 (+)NCBI
mRatBN7.23156,790,540 - 156,811,620 (+)NCBI
Rnor_6.03164,822,111 - 164,843,395 (+)NCBI
Rnor_5.03170,968,975 - 170,990,259 (+)NCBI
RGSC_v3.43159,230,673 - 159,251,755 (+)RGD
Celera3155,366,567 - 155,386,818 (+)RGD
Sequence:
Protein RefSeqs NP_001102079 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96380 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014568
  ENSRNOP00000014568.4
RefSeq Acc Id: NP_001102079   ⟸   NM_001108609
- UniProtKB: D4A2F2 (UniProtKB/TrEMBL),   A6JXM9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014568   ⟸   ENSRNOT00000014568
PB1   PDZ

Name Modeler Protein Id AA Range Protein Structure
AF-D4A2F2-F1-model_v2 AlphaFold D4A2F2 1-372 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692696
Promoter ID:EPDNEW_R3221
Type:single initiation site
Name:Pard6b_1
Description:par-6 family cell polarity regulator beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03164,822,172 - 164,822,232EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46711 BioCyc
Ensembl Genes ENSRNOG00000010883 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014568 ENTREZGENE
  ENSRNOT00000014568.5 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro OPR_PB1 UniProtKB/TrEMBL
  PAR6_homolog UniProtKB/TrEMBL
  PB1-like UniProtKB/TrEMBL
  PB1_Par6 UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report rno:362279 UniProtKB/TrEMBL
NCBI Gene 362279 ENTREZGENE
PANTHER PAR-6-RELATED UniProtKB/TrEMBL
  PTHR14102:SF4 UniProtKB/TrEMBL
Pfam PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PhenoGen Pard6b PhenoGen
PROSITE PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010883 RatGTEx
SMART PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP CAD & PB1 domains UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
UniProt A6JXM9 ENTREZGENE, UniProtKB/TrEMBL
  D4A2F2 ENTREZGENE, UniProtKB/TrEMBL
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Pard6b  par-6 family cell polarity regulator beta  Pard6b  par-6 (partitioning defective 6) homolog beta (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pard6b  par-6 (partitioning defective 6) homolog beta (C. elegans)   Pard6b_predicted  par-6 (partitioning defective 6) homolog beta (C. elegans) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pard6b_predicted  par-6 (partitioning defective 6) homolog beta (C. elegans) (predicted)      Symbol and Name status set to approved 70820 APPROVED