Fcsk (fucose kinase) - Rat Genome Database

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Gene: Fcsk (fucose kinase) Rattus norvegicus
Analyze
Symbol: Fcsk
Name: fucose kinase
RGD ID: 1307000
Description: Predicted to enable fucokinase activity. Involved in response to dopamine. Orthologous to human FCSK (fucose kinase); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH 2,6-dinitrotoluene; acrylamide; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fucokinase; Fuk; L-fucose kinase; LOC307848
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,743,746 - 55,783,873 (-)NCBIGRCr8
mRatBN7.21938,849,130 - 38,874,497 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,854,762 - 38,874,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,659,229 - 45,678,857 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,312,597 - 46,332,215 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,623,549 - 48,643,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,338,146 - 43,357,826 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,338,166 - 43,357,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01954,149,422 - 54,190,885 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,803,644 - 40,823,587 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,808,531 - 40,863,816 (-)NCBI
Celera1938,247,827 - 38,267,268 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRatautosomal dominant dyskeratosis congenita 6  ISOFCSK (Homo sapiens)8554872ClinVar Annotator: match by term: Dyskeratosis congenita and autosomal dominant 6ClinVarPMID:28492532
FcskRatCharcot-Marie-Tooth disease type 2  ISOFCSK (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 2ClinVarPMID:28492532
FcskRatChromosome 16q12 Duplication Syndrome  ISOFCSK (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 16q12 duplication syndromeClinVarPMID:25741868
FcskRatcongenital disorder of glycosylation type IIj  ISOFCSK (Homo sapiens)8554872ClinVar Annotator: match by term: COG4-CDGClinVarPMID:19494034
FcskRatCongenital Disorder of Glycosylation with Defective Fucosylation  ISOFCSK (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation with defective fucosylationClinVarPMID:28492532
FcskRatCongenital Disorder of Glycosylation with Defective Fucosylation 2  ISOFCSK (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
FcskRatNeurodevelopmental Disorders  ISOFCSK (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868 and PMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRatCongenital Disorder of Glycosylation with Defective Fucosylation 2  ISOFCSK (Homo sapiens)7240710 OMIM 

1 to 20 of 38 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOFcsk (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of FCSK mRNACTDPMID:21570461
FcskRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of FCSK mRNACTDPMID:21346803
FcskRat4,4'-sulfonyldiphenol affects methylationISOFcsk (Mus musculus)6480464bisphenol S affects the methylation of FCSK geneCTDPMID:31683443
FcskRatacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of FCSK mRNACTDPMID:28959563
FcskRatacrylamide decreases expressionISOFCSK (Homo sapiens)6480464Acrylamide results in decreased expression of FCSK mRNACTDPMID:32763439
FcskRataflatoxin B1 increases expressionISOFcsk (Mus musculus)6480464Aflatoxin B1 results in increased expression of FCSK mRNACTDPMID:19770486
FcskRatamosite asbestos increases methylationISOFCSK (Homo sapiens)6480464Asbestos and Amosite results in increased methylation of FCSK promoterCTDPMID:29626692
FcskRatamphetamine decreases expressionEXP 6480464Amphetamine results in decreased expression of FCSK mRNACTDPMID:30779732
FcskRataristolochic acid A increases expressionISOFCSK (Homo sapiens)6480464aristolochic acid I results in increased expression of FCSK mRNACTDPMID:33212167
FcskRatAroclor 1254 increases expressionISOFcsk (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of FCSK mRNACTDPMID:23650126
FcskRatarsane affects methylationISOFCSK (Homo sapiens)6480464Arsenic affects the methylation of FCSK geneCTDPMID:25304211
FcskRatarsenic atom affects methylationISOFCSK (Homo sapiens)6480464Arsenic affects the methylation of FCSK geneCTDPMID:25304211
FcskRatAzoxymethane multiple interactionsISOFcsk (Mus musculus)6480464[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FCSK mRNACTDPMID:29950665
FcskRatbenzo[a]pyrene increases expressionISOFcsk (Mus musculus)6480464Benzo(a)pyrene results in increased expression of FCSK mRNACTDPMID:22228805
FcskRatbis(2-ethylhexyl) phthalate increases expressionISOFcsk (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of FUK mRNACTDPMID:34319233
FcskRatbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of FCSK mRNACTDPMID:25181051
FcskRatbisphenol A multiple interactionsISOFCSK (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in decreased methylation of FCSK geneCTDPMID:31601247
FcskRatcaffeine increases expressionEXP 6480464Caffeine results in increased expression of FCSK mRNACTDPMID:20864626
FcskRatcopper(II) sulfate decreases expressionISOFCSK (Homo sapiens)6480464Copper Sulfate results in decreased expression of FCSK mRNACTDPMID:19549813
FcskRatdextran sulfate multiple interactionsISOFcsk (Mus musculus)6480464[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FCSK mRNACTDPMID:29950665

1 to 20 of 38 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRatcarbohydrate phosphorylation involved_inISOFcsk (Mus musculus)1624291 PMID:14686921RGDPMID:14686921
FcskRatGDP-L-fucose biosynthetic process involved_inIEAARBA:ARBA000290321600115GO_REF:0000117UniProtGO_REF:0000117
FcskRatGDP-L-fucose salvage involved_inISOFCSK (Homo sapiens)1624291 PMID:30503518RGDPMID:30503518
FcskRatGDP-L-fucose salvage involved_inIBAMGI:1916071 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
FcskRatGDP-L-fucose salvage involved_inISOFcsk (Mus musculus)1624291 PMID:14686921RGDPMID:14686921
FcskRatresponse to dopamine  IEP 13673881 RGD 

Molecular Function
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
FcskRatATP binding enablesIEAInterPro:IPR0062041600115GO_REF:0000002InterProGO_REF:0000002
FcskRatfucokinase activity enablesISOFCSK (Homo sapiens)1624291 PMID:30503518RGDPMID:30503518
FcskRatfucokinase activity enablesIBAMGI:1916071 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
FcskRatfucokinase activity enablesISOFcsk (Mus musculus)1624291 PMID:14686921 and PMID:15694600RGDPMID:14686921 and PMID:15694600
FcskRatkinase activity enablesIEAARBA:ARBA000262851600115GO_REF:0000117UniProtGO_REF:0000117
FcskRatkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
FcskRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
FcskRatphosphotransferase activity, alcohol group as acceptor enablesIEAARBA:ARBA000262651600115GO_REF:0000117UniProtGO_REF:0000117
FcskRatprotein binding enablesISOFCSK (Homo sapiens)1624291UniProtKB:O43711 more ...RGDPMID:32296183
FcskRattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
FcskRattransferase activity, transferring phosphorus-containing groups enablesIEAARBA:ARBA000262611600115GO_REF:0000117UniProtGO_REF:0000117
FcskRattransferase activity, transferring phosphorus-containing groups enablesIEAInterPro:IPR0128871600115GO_REF:0000002InterProGO_REF:0000002
1 to 13 of 13 rows

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRatfructose and mannose metabolic pathway  ISOFCSK (Homo sapiens)10402751 SMPDBSMP:00064
FcskRatfructosuria pathway  ISOFCSK (Homo sapiens)10402751 SMPDBSMP:00561
FcskRathereditary fructose intolerance syndrome pathway  ISOFCSK (Homo sapiens)10402751 SMPDBSMP:00725

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
FcskRatamino sugar metabolic pathway  IEA 6907045 KEGGrno:00520
FcskRatfructose and mannose metabolic pathway  IEA 6907045 KEGGrno:00051
FcskRatnucleotide sugar metabolic pathway  IEA 6907045 KEGGrno:00520

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Dopamine stimulated L-fucose incorporation into brain proteins is related to an increase in fucokinase activity. Jork R, etal., Biomed Biochim Acta. 1984;43(3):261-70.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:14686921   PMID:30503518  



Fcsk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,743,746 - 55,783,873 (-)NCBIGRCr8
mRatBN7.21938,849,130 - 38,874,497 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,854,762 - 38,874,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,659,229 - 45,678,857 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,312,597 - 46,332,215 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,623,549 - 48,643,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,338,146 - 43,357,826 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,338,166 - 43,357,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01954,149,422 - 54,190,885 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,803,644 - 40,823,587 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,808,531 - 40,863,816 (-)NCBI
Celera1938,247,827 - 38,267,268 (-)NCBICelera
Cytogenetic Map19q12NCBI
FCSK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381670,454,595 - 70,480,274 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1670,454,595 - 70,480,274 (+)EnsemblGRCh38hg38GRCh38
GRCh371670,488,498 - 70,514,177 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361669,045,999 - 69,071,678 (+)NCBINCBI36Build 36hg18NCBI36
Build 341669,045,998 - 69,071,677NCBI
Celera1655,014,116 - 55,039,795 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1656,320,614 - 56,346,293 (+)NCBIHuRef
CHM1_11671,895,869 - 71,921,551 (+)NCBICHM1_1
T2T-CHM13v2.01676,265,623 - 76,291,305 (+)NCBIT2T-CHM13v2.0
Fcsk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398111,609,088 - 111,629,120 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8111,609,088 - 111,629,120 (-)EnsemblGRCm39 Ensembl
GRCm388110,882,456 - 110,902,488 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,882,456 - 110,902,488 (-)EnsemblGRCm38mm10GRCm38
MGSCv378113,406,363 - 113,426,359 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,769,140 - 113,789,136 (-)NCBIMGSCv36mm8
Celera8115,106,085 - 115,126,168 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.79NCBI
Fcsk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554843,263,795 - 3,278,078 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554843,259,165 - 3,278,621 (+)NCBIChiLan1.0ChiLan1.0
FCSK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21883,682,691 - 83,709,163 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11689,612,075 - 89,637,908 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01654,534,064 - 54,559,894 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11670,294,061 - 70,318,493 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1670,294,061 - 70,318,493 (+)Ensemblpanpan1.1panPan2
FCSK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1576,442,597 - 76,463,165 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl576,443,411 - 76,462,771 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha576,403,883 - 76,424,449 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0576,879,027 - 76,899,580 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl576,879,210 - 76,951,921 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1576,705,672 - 76,721,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0576,524,033 - 76,544,592 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,016,091 - 77,036,654 (+)NCBIUU_Cfam_GSD_1.0
Fcsk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934936,452,464 - 36,472,476 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647523,116,646 - 23,136,604 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647523,116,638 - 23,136,635 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCSK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl613,471,833 - 13,506,419 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1613,471,771 - 13,492,581 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FCSK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1553,606,693 - 53,634,749 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl553,615,958 - 53,637,550 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604716,402,617 - 16,430,934 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcsk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,694,660 - 12,714,574 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,695,007 - 12,715,173 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Fcsk
170 total Variants

1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat

1 to 10 of 18 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000084739   ⟹   ENSRNOP00000069893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,854,762 - 38,874,418 (-)Ensembl
Rnor_6.0 Ensembl1943,338,171 - 43,357,822 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091720   ⟹   ENSRNOP00000069496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,854,762 - 38,874,418 (-)Ensembl
Rnor_6.0 Ensembl1943,338,166 - 43,357,505 (+)Ensembl
RefSeq Acc Id: NM_001395146   ⟹   NP_001382075
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,764,133 - 55,783,788 (-)NCBI
mRatBN7.21938,854,762 - 38,874,416 (-)NCBI
RefSeq Acc Id: XM_039097766   ⟹   XP_038953694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,743,746 - 55,783,873 (-)NCBI
mRatBN7.21938,849,130 - 38,874,497 (-)NCBI
RefSeq Acc Id: XM_039097768   ⟹   XP_038953696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,764,149 - 55,774,834 (-)NCBI
mRatBN7.21938,854,772 - 38,865,450 (-)NCBI
Protein RefSeqs NP_001382075 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953694 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953696 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92551 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069496
  ENSRNOP00000069496.1
  ENSRNOP00000069893.2
  ENSRNOP00000101537
Ensembl Acc Id: ENSRNOP00000069893   ⟸   ENSRNOT00000084739
Ensembl Acc Id: ENSRNOP00000069496   ⟸   ENSRNOT00000091720
RefSeq Acc Id: XP_038953694   ⟸   XM_039097766
- Peptide Label: isoform X1
- UniProtKB: A6IZ73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953696   ⟸   XM_039097768
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001382075   ⟸   NM_001395146
- UniProtKB: A0A0G2JVI4 (UniProtKB/TrEMBL),   A6IZ73 (UniProtKB/TrEMBL)
Fucose pyrophosphorylase   GHMP kinase C-terminal   GHMP kinase N-terminal

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVI4-F1-model_v2 AlphaFold A0A0G2JVI4 1-1090 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701144
Promoter ID:EPDNEW_R11668
Type:single initiation site
Name:Fuk_1
Description:fucokinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01943,338,174 - 43,338,234EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-5672 BioCyc
BioCyc Pathway PWY-6 [GDP-L-fucose biosynthesis II (from L-fucose)] BioCyc
BioCyc Pathway Image PWY-6 BioCyc
Ensembl Genes ENSRNOG00000059453 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084739.2 UniProtKB/TrEMBL
  ENSRNOT00000091720 ENTREZGENE
  ENSRNOT00000091720.2 UniProtKB/TrEMBL
  ENSRNOT00000138498 ENTREZGENE
Gene3D-CATH 3.30.230.120 UniProtKB/TrEMBL
InterPro Fucokinase UniProtKB/TrEMBL
  GHMP_kinase UniProtKB/TrEMBL
  GHMP_Kinase-Related UniProtKB/TrEMBL
  GHMP_kinase_C_dom UniProtKB/TrEMBL
  GHMP_kinase_C_sf UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
NCBI Gene 307848 ENTREZGENE
PANTHER L-FUCOSE KINASE UniProtKB/TrEMBL
  L-FUCOSE KINASE UniProtKB/TrEMBL
Pfam Fucokinase UniProtKB/TrEMBL
  GHMP_kinases_C UniProtKB/TrEMBL
  GHMP_kinases_N UniProtKB/TrEMBL
PhenoGen Fcsk PhenoGen
PRINTS MEVGALKINASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059453 RatGTEx
Superfamily-SCOP Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
  SSF55060 UniProtKB/TrEMBL
UniProt A0A0G2JVI4 ENTREZGENE, UniProtKB/TrEMBL
  A6IZ73 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDZ7_RAT UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Fcsk  fucose kinase  Fuk  fucokinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fuk  fucokinase   Fuk_predicted  fucokinase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fuk_predicted  fucokinase (predicted)      Symbol and Name status set to approved 70820 APPROVED